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KR102440312B9 - 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도 - Google Patents

온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Info

Publication number
KR102440312B9
KR102440312B9 KR1020200109618A KR20200109618A KR102440312B9 KR 102440312 B9 KR102440312 B9 KR 102440312B9 KR 1020200109618 A KR1020200109618 A KR 1020200109618A KR 20200109618 A KR20200109618 A KR 20200109618A KR 102440312 B9 KR102440312 B9 KR 102440312B9
Authority
KR
South Korea
Prior art keywords
fgf7
polypeptide
temperature stability
improved temperature
improved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020200109618A
Other languages
English (en)
Other versions
KR20220028520A (ko
KR102440312B1 (ko
Inventor
이정현
임형순
안영준
이경원
정예은
차기원
이원규
Original Assignee
한국해양과학기술원
재단법인 오송첨단의료산업진흥재단
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Publication date
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Priority to KR1020200109618A priority Critical patent/KR102440312B1/ko
Publication of KR20220028520A publication Critical patent/KR20220028520A/ko
Application granted granted Critical
Publication of KR102440312B1 publication Critical patent/KR102440312B1/ko
Publication of KR102440312B9 publication Critical patent/KR102440312B9/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020200109618A 2020-08-28 2020-08-28 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도 Active KR102440312B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020200109618A KR102440312B1 (ko) 2020-08-28 2020-08-28 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020200109618A KR102440312B1 (ko) 2020-08-28 2020-08-28 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Publications (3)

Publication Number Publication Date
KR20220028520A KR20220028520A (ko) 2022-03-08
KR102440312B1 KR102440312B1 (ko) 2022-09-05
KR102440312B9 true KR102440312B9 (ko) 2023-03-23

Family

ID=80813523

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020200109618A Active KR102440312B1 (ko) 2020-08-28 2020-08-28 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Country Status (1)

Country Link
KR (1) KR102440312B1 (ko)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE237633T1 (de) * 1994-10-13 2003-05-15 Amgen Inc Analogen des keratinozytenwachstumfaktors
US6077692A (en) * 1995-02-14 2000-06-20 Human Genome Sciences, Inc. Keratinocyte growth factor-2
DK0950100T3 (da) * 1996-08-13 2004-06-07 Human Genome Sciences Inc Keratinocytvækstfaktor-2- (KGF-2- eller fibroblastvækstfaktor-12-, FGF-12-) mutanter
WO1999055861A2 (en) * 1998-04-28 1999-11-04 Eisai Co., Ltd. Fibroblast growth factor mutein compositions and methods of use therefor
WO2001072957A2 (en) * 2000-03-31 2001-10-04 Nobuyuki Itoh Fibroblast growth factor-like molecules and uses thereof
US20040009481A1 (en) * 2001-06-11 2004-01-15 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of human prostate cancer
KR100484653B1 (ko) * 2004-05-06 2005-04-20 주식회사 대웅 원핵세포에서 활성형의 가용성 단백질을 제조하는 방법 및 이를 위한 폴리시스트론 벡터
WO2007008708A2 (en) * 2005-07-08 2007-01-18 Ohio University Methods of predicting hyp-glycosylation sites for proteins expressed and secreted in plant cells, and related methods and products
KR101930916B1 (ko) * 2009-11-30 2018-12-19 티슈 테라피스 리미티드 피브로넥틴:성장 인자 키메라
ITRM20120404A1 (it) * 2012-08-09 2014-02-10 Univ Roma Uso del kgf nel trattamento di disturbi della menopausa
KR102015116B1 (ko) * 2018-05-04 2019-10-21 (주)메디톡스 표적 단백질을 코딩하는 폴리뉴클레오티드를 포함하는 재조합 미생물로부터 유래한 세포외 소낭 및 그의 용도
CN109402130A (zh) * 2018-11-23 2019-03-01 成都中医药大学附属医院 一种重组人角质细胞生长因子-1及其制备方法和用途
CN110339345B (zh) * 2019-07-30 2022-11-29 重庆派金生物科技有限公司 一种重组人截短型角质细胞生长因子-1滴眼液及其制备方法和应用

Also Published As

Publication number Publication date
KR20220028520A (ko) 2022-03-08
KR102440312B1 (ko) 2022-09-05

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KR102440312B9 (ko) 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

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