KR102304659B1 - A kit for measuring blood viscosity - Google Patents

Abstract

The present invention relates to a kit for measuring blood viscosity, and more particularly, comprising an upper sample holder coupled to an upper plate of a rheometer and a lower sample holder coupled to a lower plate of the rheometer, wherein blood is transferred to the upper sample holder and It relates to a kit for measuring blood viscosity, characterized in that after measuring the viscosity of blood by placing it in close contact between the lower sample holders, the kit for measuring blood viscosity is detached from the rheometer and used for a single use.
The present invention can provide a kit for measuring blood viscosity that can be used simply and safely without contaminating the upper plate and lower plate of the rheometer when measuring blood viscosity.
In addition, the present invention provides a kit for measuring blood viscosity that can improve the accuracy and reliability of blood viscosity analysis by manufacturing an upper sample holder and a lower sample holder excellent in transparency, heat resistance, chemical resistance and surface flatness by injection molding a polymer composition. can provide

Description

A kit for measuring blood viscosity

The present invention relates to a kit for measuring blood viscosity, and more particularly, comprising an upper sample holder coupled to an upper plate of a rheometer and a lower sample holder coupled to a lower plate of the rheometer, wherein blood is transferred to the upper sample holder and It relates to a kit for measuring blood viscosity, characterized in that after measuring the viscosity of blood by placing it in close contact between the lower sample holders, the kit for measuring blood viscosity is detached from the rheometer and used for a single use.

A rheometer is a generic term for devices that measure the rheological properties of pastes, gels, liquids, etc., and various properties such as viscosity, viscoelasticity, plasticity, yield stress, and stress relaxation behavior of fluids can be analyzed through the rheometer.

These rheometers can be used in various industries such as polymers, ceramics, food, paints, coatings, cosmetics, etc., and are largely classified into rotational rheometers and capillary rheometers.

After loading the sample between two plates, the rotational rheometer deforms the sample by applying a rotational shear stress to the sample when torque is applied to the upper or lower plate. At this time, various information can be obtained by measuring the behavior of the sample. .

The capillary rheometer applies a force to the sample under high pressure to discharge the sample through the die, and at this time, the pressure drop of the sample can be measured to measure the behavior of the fluid.

Rotational rheometer is 1 ~ 10 s ^- In contrast to observe the behavior of the fluid at low shear rate of ¹ is desired, capillary rheometer may be analyzed at least 100 s ^-1 high shear rates.

Meanwhile, for blood analysis, blood is placed between the upper and lower plates of the rheometer and then the rheometer is operated to measure the viscosity. can cause

In addition, it is cumbersome to wash the contact surface of the upper plate and the lower plate every time measurement is performed, and the contact surface is rather contaminated by washing, which may affect subsequent viscosity analysis.

Therefore, there is a need for a kit for measuring blood viscosity that can be used simply without contaminating the upper and lower plates of the rheometer when measuring blood viscosity.

Korean Patent No. 10-0877494

An object of the present invention is to provide a kit for measuring blood viscosity that can be used simply and safely without contaminating the upper plate and lower plate of the rheometer when measuring blood viscosity. It is a reality that blood is exposed to limitations in measuring by conventional techniques due to its low viscosity, and the present invention is to solve this problem.

In addition, the present invention includes an upper sample holder coupled to the upper plate of the rheometer and a lower sample holder coupled to the lower plate of the rheometer, so that the blood is placed in close contact between the upper sample holder and the lower sample holder to increase the viscosity of the blood. An object of the present invention is to provide a kit for measuring blood viscosity, characterized in that the kit for measuring blood viscosity is detached from the rheometer and used for a single use after measuring .

In addition, the present invention provides a kit for measuring blood viscosity that can improve the accuracy and reliability of blood viscosity analysis by manufacturing an upper sample holder and a lower sample holder excellent in transparency, heat resistance, chemical resistance and surface flatness by injection molding a polymer composition. intended to provide

In order to achieve the above object, the present invention uses the LAOS (Large Amplitude Oscillatory Shear) method, which is the latest rheological technology, to measure the stable viscosity of a material having a low viscosity in the operation of a rheometer to overcome the limitations of the existing technology. aim to overcome.

The present invention provides an upper sample holder coupled to the upper plate of the rheometer; and a lower sample holder coupled to the lower plate of the rheometer;

In order to measure the viscosity of blood, the upper sample holder is coupled to the upper plate of the rheometer, the lower sample holder is coupled to the lower plate of the rheometer, and the blood is placed in close contact between the upper sample holder and the lower sample holder. , It provides a kit for measuring blood viscosity, characterized in that the kit for measuring blood viscosity is detached from the rheometer and used for a single use after measuring the viscosity of blood.

In an embodiment of the present invention, the upper sample holder and the lower sample holder are manufactured by injection molding a polymer composition.

In one embodiment of the present invention, the polymer composition is characterized in that it comprises a thermoplastic resin, an antibacterial agent and a heat stabilizer.

In one embodiment of the present invention, the polymer composition is characterized in that it contains 1 to 10 parts by weight of the antibacterial agent and 1 to 5 parts by weight of the heat stabilizer with respect to 100 parts by weight of the thermoplastic resin.

In one embodiment of the present invention, the polymer composition is characterized in that it further comprises 1 to 10 parts by weight of a polyester polyol based on 100 parts by weight of the thermoplastic resin.

The present invention also provides a rheometer for measuring blood viscosity to which the kit for measuring blood viscosity is attached.

In one embodiment of the present invention, the rheometer employs a parallel plate and measures the viscosity of blood by increasing the strain using an operation of reciprocating rotation (oscillation).

The present invention can provide a kit for measuring blood viscosity that can be used simply and safely without contaminating the upper plate and lower plate of the rheometer when measuring blood viscosity.

In addition, the present invention includes an upper sample holder coupled to the upper plate of the rheometer and a lower sample holder coupled to the lower plate of the rheometer, so that the blood is placed in close contact between the upper sample holder and the lower sample holder to increase the viscosity of the blood. It is possible to provide a kit for measuring blood viscosity, characterized in that the kit for measuring blood viscosity is detached from the rheometer and used for a single use after measuring .

In addition, the present invention provides a kit for measuring blood viscosity that can improve the accuracy and reliability of blood viscosity analysis by manufacturing an upper sample holder and a lower sample holder excellent in transparency, heat resistance, chemical resistance and surface flatness by injection molding a polymer composition. can provide

1 shows a kit for measuring blood viscosity according to an embodiment of the present invention: (a) an upper sample holder, (b) a lower sample holder.
2 shows an example in which a kit for measuring blood viscosity according to an embodiment of the present invention is mounted on a rheometer.

Hereinafter, the present invention will be described in detail based on the drawings and examples. Terms, drawings, examples, etc. used in the present invention are merely exemplified to explain the present invention in more detail and help those of ordinary skill in the art to understand, and the scope of the present invention should not be construed as being limited thereto. .

Technical terms and scientific terms used in the present invention represent meanings commonly understood by those of ordinary skill in the art to which this invention belongs, unless otherwise defined.

The present invention provides an upper sample holder 100 coupled to the upper plate 10 of the rheometer; and a lower sample holder 200 coupled to the lower plate 20 of the rheometer; relates to a kit for measuring blood viscosity including ( FIG. 1 ).

In the present invention, for measuring the viscosity of blood 300, the upper sample holder 100 is coupled to the lower surface of the upper plate 10 of the rheometer, and the lower sample holder 200 is connected to the upper surface of the lower plate 20 of the rheometer. binds to (FIG. 2).

After placing the blood 300 in close contact between the upper sample holder 100 and the lower sample holder 200, a rheometer is operated to analyze the blood behavior.

After analyzing the viscosity and behavior of blood, the kit for measuring blood viscosity may be detached from the rheometer and used for one-time use.

The upper sample holder may include a coupling part 110 on an upper surface thereof, and the coupling part 110 is coupled to the lower surface of the upper plate of the rheometer, so that the upper sample holder may be mounted on the lower surface of the upper plate.

The coupling part may be an adhesive part, and the adhesive part formed on the upper surface of the upper sample holder may be coupled to the lower surface of the upper plate of the rheometer, so that the upper sample holder may be mounted on the lower surface of the upper plate.

Alternatively, the upper sample holder includes a groove or protrusion as the coupling portion 110 on the edge of the upper surface, and the groove or protrusion is coupled with the protrusion or groove formed in the corresponding portion of the lower surface of the upper plate of the rheometer, whereby the upper sample holder is It may be mounted on the lower surface of the upper plate.

The lower sample holder may include a coupling part 210 on a lower surface thereof, and the coupling part 210 is coupled to the upper surface of the lower plate of the rheometer, so that the lower sample holder may be mounted on the upper surface of the lower plate.

The coupling part may be an adhesive part, and the adhesive part formed on the lower surface of the lower sample holder may be coupled to the upper surface of the lower plate of the rheometer, so that the lower sample holder may be mounted on the upper surface of the lower plate.

Alternatively, the lower sample holder includes a groove or protrusion as the coupling portion 210 on the edge of the lower surface, and the groove or protrusion is coupled with the protrusion or groove formed in the corresponding portion of the upper surface of the lower plate of the rheometer, whereby the lower sample holder is It may be mounted on the upper surface of the lower plate.

At this time, the lower sample holder may include a blood receiving part 220 capable of accommodating the blood flowing down when the rheometer is operated on the edge of the upper surface, and receiving the blood discharged outside when the viscosity is measured in the blood receiving part 220 By doing so, contamination of the rheometer can be prevented.

In order to analyze blood using a rheometer, blood is placed between the upper plate and the lower plate of the rheometer, and then the viscosity is measured by operating the rheometer.

At this time, the upper plate and the lower plate come into contact with blood, and these contact surfaces are contaminated with blood, which may cause an error when measuring the viscosity of other samples later.

In order to prevent this, the contact surface of the upper plate and the lower plate must be washed before or after measuring the viscosity of the blood. This cleaning process takes time and money, and rather the contact surface is contaminated by washing, which affects the viscosity analysis later. may give

The kit for measuring blood viscosity of the present invention includes an upper sample holder coupled to the upper plate of the rheometer and a lower sample holder coupled to the lower plate of the rheometer, so that the upper and lower plates of the rheometer are measured when measuring blood viscosity. It is simple and safe to use without contamination.

In the present invention, after measuring the viscosity of blood by placing the blood in close contact between the upper sample holder and the lower sample holder, the blood viscosity measuring kit can be detached from the rheometer and used for one time use.

In addition, the present invention can improve the accuracy and reliability of blood viscosity analysis by injection molding a polymer composition to manufacture an upper sample holder and a lower sample holder having excellent transparency, heat resistance, chemical resistance and surface flatness.

The upper sample holder and the lower sample holder of the present invention may be manufactured by injection molding a polymer composition.

The polymer composition may include a thermoplastic resin, an antibacterial agent, and a heat stabilizer.

The polymer composition may include 1 to 10 parts by weight of an antibacterial agent and 1 to 5 parts by weight of a heat stabilizer based on 100 parts by weight of the thermoplastic resin.

Examples of the thermoplastic resin include acrylic resins such as polymethyl methacrylate, polyethyl methacrylate, polymethyl acrylate, polyethyl acrylate, and acrylic copolymer; polystyrene; polycarbonate; polyesters such as polyethylene terephthalate and polybutylene terephthalate; polyamide; Acrylonitrile-butadiene-styrene (ABS) and the like can be used without limitation.

For example, as the thermoplastic resin, an acrylic resin and polystyrene may be used at the same time, in which case the weight ratio of the acrylic resin and polystyrene is preferably 70 to 90:10 to 30, and when the weight ratio satisfies the above numerical range, transparency, heat resistance, and Surface flatness can be maximized.

The antibacterial agent is used to impart antibacterial action, sterilization action, etc., and zinc oxide, silica, alumina, zeolite, bentonite, silver powder, silver ion antibacterial agent powder, zinc powder, copper powder, etc. may be used.

The antimicrobial agent is preferably used in an amount of 1 to 10 parts by weight based on 100 parts by weight of the thermoplastic resin, and when the content is less than 1 part by weight, the antimicrobial improvement is insignificant, and when the content exceeds 10 parts by weight, transparency and heat resistance are rather reduced. .

The heat stabilizer is used to improve weather resistance, heat resistance and durability, and phenol antioxidants, alkylated monophenols, alkylthiomethylphenols, hydroquinones, alkylated hydroquinones, hydroxybenzyl, triazines, etc. may be used without limitation.

The content of the heat stabilizer is preferably 1 to 5 parts by weight based on 100 parts by weight of the thermoplastic resin, and when the content is less than 1 part by weight, weather resistance, heat resistance and durability are deteriorated, and when it exceeds 5 parts by weight, transparency and workability are rather reduced. .

In addition, the polymer composition may further include a polyester polyol, and the polyester polyol includes a plurality of hydroxyl groups in a molecule, thereby improving the bonding strength of the composition.

Polyester polyols can be prepared by polymerizing glycol components such as ethylene glycol, propylene glycol, butanediol, 3-methylpentanediol, hexanediol, and bisoxymethylcyclohexane with acid components such as adipic acid, terephthalic acid, and isophthalic acid. .

It is preferable that the weight average molecular weight of the polyester polyol is 1,000 to 10,000 g/mol. When the weight average molecular weight satisfies the above numerical range, heat resistance, durability and weather resistance of the composition can be maximized.

The content of the polyester polyol is preferably 1 to 10 parts by weight based on 100 parts by weight of the thermoplastic resin. When the content is less than 1 part by weight, the effect of addition is insignificant, and when it exceeds 10 parts by weight, heat resistance and workability are rather deteriorated.

The composition may further include molybdenum disulfide, and the molybdenum disulfide may improve surface flatness, abrasion resistance and scratch resistance by imparting self-lubricating properties.

The molybdenum disulfide is preferably 1 to 5 parts by weight based on 100 parts by weight of the thermoplastic resin. When the content is less than 1 part by weight, the effect of addition is insignificant, and when it exceeds 5 parts by weight, transparency and heat resistance are rather deteriorated.

In addition, the composition may further include a silane coupling agent. Since blood contains a large amount of water, a silane coupling agent may be used to improve wettability between the blood and the upper and lower sample holders.

The silane coupling agent has an organic functional group capable of bonding with an organic compound and a hydrolyzing group capable of reacting with an inorganic material, and can improve durability, weather resistance, heat resistance, etc. by improving interfacial adhesion of the composition.

The silane coupling agent includes an alkyl group-containing silane coupling agent, an amino group-containing silane coupling agent, an epoxy group-containing silane coupling agent, an acrylate group-containing silane coupling agent, an isocyanate group-containing silane coupling agent, a mercapto group-containing silane coupling agent, and a fluorine group-containing silane A coupling agent, a vinyl group-containing silane coupling agent, etc. are used.

In particular, it is preferable to use a silane coupling agent mixture composed of 60 to 80 wt% of an acrylate group-containing silane coupling agent and 20 to 40 wt% of an epoxy group-containing silane coupling agent.

Acrylate group-containing silane coupling agents include 3-methacryloxypropylmethyldimethoxysilane, 3-methacryloxypropyltrimethoxysilane, 3-methacryloxypropylmethyldiethoxysilane, and 3-methacryloxypropyltriethane. oxysilane, 3-acryloxypropyltrimethoxysilane, methacryloxymethyltriethoxysilane, methacryloxymethyltrimethoxysilane, and the like.

Epoxy group-containing silane coupling agents include 2-glycidoxyethylmethyldimethoxysilane, 2-glycidoxyethylmethyldiethoxysilane, 3-glycidoxypropylmethyldimethoxysilane, 3-glycidoxypropylmethyldiethoxysilane glycidoxy C _1-4 alkyl C _1-4 alkyl C _1-4 alkoxysilane such as; _{Glycidoxy C 1} such as 2-glycidoxyethyltrimethoxysilane, 2-glycidoxyethyltriethoxysilane, 3-glycidoxypropyltrimethoxysilane, and 3-glycidoxypropyltriethoxysilane _-4 alkyl C _1-4 alkoxysilane; 2-(3,4-epoxycyclohexyl)ethylmethyldimethoxysilane, 2-(3,4-epoxycyclohexyl)ethylmethyldiethoxysilane, 3-(3,4-epoxycyclohexyl)propylmethyldimethoxysilane _{Epoxy C 3-10} cycloalkyl C _1-4 alkyl C _1-4 alkyl C _1-4 alkoxysilane such as , 3-(3,4-epoxycyclohexyl)propylmethyldiethoxysilane; 2-(3,4-epoxycyclohexyl)ethyltrimethoxysilane, 2-(3,4-epoxycyclohexyl)ethyltriethoxysilane, 3-(3,4-epoxycyclohexyl)propyltrimethoxysilane _{and epoxy C 3-10} cycloalkyl C _1-4 alkyl C _1-4 alkoxysilane such as , 3-(3,4-epoxycyclohexyl)propyltriethoxysilane.

The content of the silane coupling agent is preferably 1 to 10 parts by weight based on 100 parts by weight of the thermoplastic resin. When the content is less than 1 part by weight, the effect of addition is insignificant. The interfacial adhesive properties and heat resistance are lowered.

In addition, the composition may further include a copolymer of an acrylate group-containing silane coupling agent and an acrylic acid monomer.

A plurality of carboxyl groups included in the copolymer may improve heat resistance and surface flatness of the composition.

The acrylate group-containing silane coupling agent is 3-methacryloxypropylmethyldimethoxysilane, 3-methacryloxypropyltrimethoxysilane, 3-methacryloxypropylmethyldiethoxysilane, 3-methacryloxypropyltri ethoxysilane, 3-acryloxypropyltrimethoxysilane, methacryloxymethyltriethoxysilane, and methacryloxymethyltrimethoxysilane.

The acrylic acid monomer is acrylic acid, methacrylic acid, methyl acrylic acid, ethyl acrylic acid, butyl acrylic acid, 2-ethyl hexyl acrylic acid, decyl acrylic acid, methyl methacrylic acid, ethyl methacrylic acid, butyl methacrylic acid, 2-ethyl hexyl methacrylic acid , and decyl methacrylic acid.

The weight ratio of the acrylate group-containing silane coupling agent and the acrylic acid monomer is preferably 10 to 30:70 to 90, and when the weight ratio is less than 10:90, the bonding strength of the composition is reduced, and when it exceeds 30:70, the heat resistance is reduced. .

The content of the copolymer of the acrylate group-containing silane coupling agent and the acrylic acid monomer is preferably 1 to 10 parts by weight based on 100 parts by weight of the thermoplastic resin, and when the content of the copolymer is less than 1 part by weight, the effect of addition is insignificant, When it exceeds 10 parts by weight, workability is deteriorated.

The composition may further include an anti-wear agent to improve abrasion resistance.

A fatty acid ester of sorbitan is used as the antiwear agent, and sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan monooleate, and the like may be used.

The anti-wear agent includes a polar portion and a non-polar portion, the polar portion is adsorbed to the polymer surface, the non-polar portion is composed of a long chain serves to reduce friction of the composition and prevent wear.

The content of the anti-wear agent is preferably 1 to 5 parts by weight based on 100 parts by weight of the thermoplastic resin. When the content is less than 1 part by weight, the effect of addition is insignificant, and when the content exceeds 5 parts by weight, heat resistance may be reduced.

The antiwear agent may further include a fatty acid ester of polyoxyethylene sorbitan.

As the fatty acid ester of polyoxyethylene sorbitan, polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, etc. may be used without limitation. have.

When the fatty acid ester of sorbitan and the fatty acid ester of polyoxyethylene sorbitan are simultaneously used as the abrasion resistance agent, the weight ratio of the fatty acid ester of sorbitan and the fatty acid ester of polyoxyethylene sorbitan is preferably 60 to 80: 20 to 40. . When the above range is satisfied, the abrasion resistance and heat resistance of the composition may be maximized.

In addition, the composition may further include a copolymer of aromatic methacrylate and alkyl methacrylate, and the copolymer preferably has a weight average molecular weight of 5,000 to 30,000 g/mol.

The weight ratio of the aromatic methacrylate and the alkyl methacrylate is preferably 10-50:50-90, and when the weight ratio satisfies the numerical range, heat resistance, transparency, and surface flatness of the composition can be maximized.

The alkyl methacrylate may include methyl methacrylate, ethyl methacrylate, n-propyl methacrylate, isopropyl methacrylate, n-butyl methacrylate, isobutyl methacrylate, and the like.

As the aromatic methacrylate, phenyl methacrylate, naphthyl methacrylate, benzyl methacrylate, and the like may be used.

The content of the copolymer is preferably 1 to 5 parts by weight based on 100 parts by weight of the thermoplastic resin. When the content is less than 1 part by weight, the effect of addition is insignificant, and when the content exceeds 5 parts by weight, heat resistance may be lowered. .

The present invention also relates to a rheometer for measuring blood viscosity to which the kit for measuring blood viscosity is attached.

The rheometer employs a parallel plate and can measure the viscosity of blood by increasing the strain using an operation of reciprocating rotation (oscillation).

Hereinafter, the present invention will be described in detail through Examples and Comparative Examples. The following examples are only exemplified for the practice of the present invention, and the content of the present invention is not limited by the following examples.

(Example 1)

A polymer composition was prepared by mixing 100 parts by weight of polymethyl methacrylate, 5 parts by weight of zeolite, and 3 parts by weight of hydroquinone.

The polymer composition was put into a twin-screw extruder and processed at 230° C. to prepare pellets.

The prepared pellets were put into an injection machine at 230° C. to prepare a sample holder.

(Example 2)

A sample holder was prepared in the same manner as in Example 1, except that 0.5 parts by weight of zeolite was used.

(Example 3)

A sample holder was prepared in the same manner as in Example 1, except that 15 parts by weight of zeolite was used.

(Example 4)

A sample holder was prepared in the same manner as in Example 1, except that 80 parts by weight of polymethyl methacrylate and 20 parts by weight of polystyrene were used instead of 100 parts by weight of polymethyl methacrylate.

(Example 5)

A polyester polyol having a weight average molecular weight of 5,000 g/mol was prepared by polymerization of ethylene glycol and terephthalic acid.

A sample holder was prepared in the same manner as in Example 1, except that 5 parts by weight of the polyester polyol was additionally used.

(Example 6)

A sample holder was prepared in the same manner as in Example 1, except that 3 parts by weight of molybdenum disulfide was additionally used.

(Example 7)

A sample holder was prepared in the same manner as in Example 6, except that 2 parts by weight of 3-methacryloxypropyltrimethoxysilane and 1 part by weight of 3-glycidoxypropyltrimethoxysilane were additionally used.

(Example 8)

A sample holder was prepared in the same manner as in Example 7, except that 5 parts by weight of a copolymer of 3-methacryloxypropyltrimethoxysilane and acrylic acid was additionally used.

(Comparative Example 1)

A sample holder was prepared in the same manner as in Example 1, except that hydroquinone was not used.

The characteristics of the sample holders prepared in Examples and Comparative Examples were measured, and the results are shown in Table 1 below.

For heat resistance, the yellowing degree of the sample holder was visually observed after heating the sample holder in a hot-air circulation heating furnace maintained at 80° C., and marked as excellent, excellent, average, and poor.

For chemical resistance, the sample holder was immersed in 10% by weight of sulfuric acid at room temperature for 2 days, and then the state of the sample holder was observed and marked as excellent, good, average, and poor.

The coefficient of friction was calculated by measuring the tangential friction force generated during normal load and rotation at room temperature using a roller-and-disk tester.

Transmittance was evaluated according to ASTM D 1003 for a specimen having a thickness of 3 mm.

division Example comparative example One 2 3 4 5 6 7 8 One heat resistance Great commonly commonly eminence Great eminence eminence eminence error chemical resistance Great commonly commonly Great eminence eminence eminence eminence error coefficient of friction 0.36 0.40 0.41 0.33 0.34 0.26 0.28 0.29 0.42 transmittance
(%) 90.6 91.8 89.2 91.3 89.8 89.6 88.3 87.6 93.5

From the results of Table 1, it can be confirmed that the compositions of Examples 1 to 8 are excellent in heat resistance, chemical resistance, surface flatness and transmittance. In particular, Examples 1, 4 to 8 have the most excellent properties.

On the other hand, it can be seen that the composition of Comparative Example 1 has inferior properties compared to the Example.

10: upper plate 20: lower plate
100: upper sample holder 110: coupling part
200: lower sample holder 210: coupling portion
220: blood receptor 300: blood

Claims (7)

an upper sample holder coupled to the upper plate of the rheometer; and
In a kit for measuring blood viscosity comprising a; a lower sample holder coupled to the lower plate of the rheometer,
coupling the upper sample holder to the upper plate of the rheometer for measuring the viscosity of blood;
coupling the lower sample holder to the lower plate of the rheometer;
The blood is placed in close contact between the upper sample holder and the lower sample holder,
The lower sample holder includes a blood receiving part accommodating the blood flowing down when the rheometer is operated on the edge of the upper surface, and the blood receiving part accommodates the blood discharged outside when measuring the viscosity, thereby preventing contamination of the rheometer,
The upper sample holder and the lower sample holder are manufactured by injection molding a polymer composition,
The polymer composition includes a thermoplastic resin, an antibacterial agent and a heat stabilizer,
The polymer composition comprises 1 to 10 parts by weight of an antibacterial agent and 1 to 5 parts by weight of a heat stabilizer based on 100 parts by weight of the thermoplastic resin,
A kit for measuring blood viscosity, characterized in that after measuring the viscosity of blood, the kit for measuring blood viscosity is detached from the rheometer and used for a single use.
delete delete delete According to claim 1,
The polymer composition is a kit for measuring blood viscosity, characterized in that it further comprises 1 to 10 parts by weight of a polyester polyol based on 100 parts by weight of the thermoplastic resin.
A rheometer for measuring blood viscosity to which the kit for measuring blood viscosity of claim 1 is attached.
7. The method of claim 6,
A rheometer for measuring blood viscosity, characterized in that it measures the viscosity of blood by increasing the strain by employing a parallel plate and using an oscillation motion.

Images