KR101441688B1 - Liquid cleaner composition - Google Patents

Abstract

The present invention relates to a composition comprising (A) 5 to 20% by weight of an alkyl glycoside, (B) 10 to 30% by weight of a hydroxycarboxylic acid type chelating agent, and (C) 1 to 10% by weight of a polycarboxylic acid type chelating agent. Wherein the weight ratio of (A) / (B) is 0.2 to 1, and the weight ratio of (B) / (C) is 1 to 10.

Description

[0001] LIQUID DETERGENT COMPOSITION [0002]

The present invention relates to a liquid detergent composition and a method for removing stains from medical care.

Heretofore, a heavy liquid detergent for medical use has been developed with an emphasis on decontamination of contamination such as mud, sebum, and oil, and so-called stain contamination such as manure or juice has not been sufficiently decontaminated. Typically, bleaching agents based on oxidative bleaching are used for such stain contamination, and general consumers have used the so-called general liquid detergent and bleaching agent separately to remove contamination.

On the other hand, there is a product group called liquid medical detergent for infants, and the safety such as no bleaching, no moon, and unmanned is put on the whole in order to wash infant diaper, medicine, bedding, etc., This was a product group with high cleanliness and stain contamination. Most of these liquid medical detergents for babies are generally weakly alkaline or alkaline detergents based on fatty acid soap and polyoxyethylene alkyl ether.

JP-A 2002-138364 discloses a cleaning method of a diaper using an alkaline cleaning liquid containing a water-soluble chelating agent and a bleaching agent under specific conditions of a high-mix chelating agent, a high alkaline pH 10 or higher, and a temperature of 50 ° C or higher.

Further, JP-A5-239493 and JP-A-6-299191 disclose that a liquid detergent composition using an alkyl glycoside (alkyl polysaccharide surfactant) is excellent in detergency and is excellent in reduction of medical damage and improvement of storage stability of a product Is valid. JP-A4-292697 also discloses a detergent composition containing alkyl polyglycoxides and other specific nonionic surface active agents.

The present invention relates to a composition comprising (A) 5 to 20% by weight of an alkyl glycoside, (B) 10 to 30% by weight of a hydroxycarboxylic acid type chelating agent, and (C) 1 to 10% by weight of a polycarboxylic acid type chelating agent. (A) / (B) weight ratio of 0.2 to 1, and (B) / (C) weight ratio of 1 to 10.

The present invention relates to a method of stain decontamination of medical care which brings the medical liquid into contact with the liquid detergent composition and to the use of the liquid detergent composition for medical purposes.

Although the method of JP-A 2002-138364 is suitable as a cleaning method for business, it is difficult to say that this method is suitable as a method to be carried out simply and routinely in ordinary households. Further, in the conventional medical liquid medical detergent for babies, improvement is required in terms of occurrence of slippery and skin irritation when the undiluted solution is in the hands, stiffness of medical treatment due to cumulative cleaning, and the like. In this regard, JP-A5-239493 and JP-A-6-299191 disclose a liquid detergent composition that can reduce medical damage and improve the storage stability of a product. In addition to this effect, , Further improvement is required in that excellent washing power is obtained also against stain contamination caused by feces and urine. JP-A4-292697 does not mention that a liquid detergent composition has a transparent appearance and a stable composition is obtained.

Generally, it is effective to add a large amount of a chelating agent in order to select a high cleaning power against stain contamination, such as contamination or juice contamination originating from faeces such as feces, urine, etc. Conventionally, A composition containing an active agent has not been found.

INDUSTRIAL APPLICABILITY The present invention provides a detergent composition which exhibits excellent detergency against stain contamination originating from stain contamination, particularly stool such as faeces and urine, and has no slippery or skin roughness when the undiluted solution is in the hand, And a liquid detergent composition excellent in stability.

The inventors of the present invention have found that a detergent composition using an alkylglycoside, a hydroxycarboxylic acid type chelating agent and a polycarboxylic acid type chelating agent in a specific amount in a specified ratio exhibits excellent cleaning power against stain contamination and is a storage-stable composition.

According to the present invention, it is possible to provide a liquid detergent composition which is hypoallergenic, excellent in appearance and excellent in stability without remarkable relief of irritation and damage to skin, hair or cloth, excellent in detergency and no stiffness due to cumulative cleaning / RTI > The liquid detergent composition of the present invention is excellent in cleansing property against infectious diseases, diaper, bedding, etc., that is, against stain contamination. To a liquid detergent composition particularly suitable for medical use, and a medical stain removing method.

≪ Component (A) >

As the component (A), an alkyl glycoside represented by the following general formula (I) is preferable.

R^One(OR²)_pG_q (I)

(Wherein R ¹ represents an alkyl or alkenyl group having 8 to 18 carbon atoms in the linear or branched chain or an alkyl (having 2 to 12 carbon atoms) phenyl group, R ² represents an alkylene group having 2 to 4 carbon atoms, G represents Is a residue derived from a reducing sugar (sugar) having 5 to 6 carbon atoms, and p has an average value of 0 to 5. q has an average value of 1 to 10.]

In the general formula (I), R ¹ preferably has 9 to 14 carbon atoms in terms of solubility, foaming property and cleaning property. In addition, R ² preferably has 2 to 3 carbon atoms in terms of water solubility and the like. The value of p regulates the water solubility and crystallinity, and the larger the value of p, the higher the water solubility and the lower the crystallinity. The preferred range is 0 to 2, particularly 0. and q is preferably in the range of 1 to 4. q is preferably selected in consideration of the physical properties derived from the hydrophobic group of R < ^{1 &} gt ;. For example, when R < ^{1 >} is a hydrophobic group having an average carbon number of 9 to 11, q is in the range of 1 to 1.4, It is preferable to select q = 1.2 to 4.0. The average degree of polymerization of sugar q can be determined by proton NMR. The binding mode of this oligosaccharide is any one of 1-2, 1-3, 1-4 or 1-6 linkage, α- or β-pyranoside linkage or furanoside linkage, or a combination thereof. G in the general formula (I) is determined by the monosaccharide or polysaccharide as a raw material. Examples of the monosaccharide include glucose, fructose, galactose, xylose, mannose, ricinose, arabinose and the like Examples of polysaccharides include maltose, xylobiose, isomaltose, cellobiose, gentivius, lactose, sucrose, nigerose, trranose, raffinose, gentianose, These may be used singly or in combination of two or more. Of these, glucose, fructose and the like are preferred as the monosaccharide raw material and maltose and sucrose as the polysaccharide raw material in terms of availability and low cost.

The liquid detergent composition of the present invention contains 5 to 20% by weight, preferably 5 to 15% by weight, more preferably 5 to 10% by weight of the component (A) from the viewpoint of detergency and hypoallergenicness.

≪ Component (B) >

The hydroxycarboxylic acid type chelating agent is a chelating agent having a hydroxy group and a carboxylic acid. Examples of the component (B) include citric acid, gluconic acid, malic acid, peptonic acid, lactic acid, tartaric acid, and hydroxyacetic acid (glycolic acid). These may be salts, and examples thereof include alkali metal salts such as sodium salts and potassium salts, alkanolamine salts, and aliphatic amine salts. Preferably, it is citric acid, gluconic acid, malic acid and tartaric acid, more preferably citric acid.

The liquid detergent composition of the present invention contains 10 to 30% by weight, preferably 10 to 25% by weight, more preferably 15 to 25% by weight of the component (B) from the viewpoints of washing power and stability. The content of the component (B) is not a salt but a content as an acid.

In the liquid detergent composition of the present invention, the weight ratio of the component (A) to the component (B) is from 0.2 to 1, preferably from 0.33 to 1.0, in terms of cleaning power, hypoallergenic property, appearance, 1, and more preferably 0.33 to 0.7.

The liquid detergent composition of the present invention further contains (C) a polycarboxylic acid type chelating agent (hereinafter referred to as component (C)).

As the component (C), a polycarboxylic acid polymer and / or a salt thereof are preferable. Specifically, one or two or more selected from polyacrylic acid and its salt, polymaleic acid and its salt, and acrylic acid-maleic acid copolymer and its salt are preferable. The salt may be a part or all, and the salt is preferably an alkali metal salt such as sodium or potassium, or an organic amine salt.

The weight average molecular weight of the polyacrylic acid and its salt is preferably 1,000 to 20,000, particularly preferably 2,000 to 15,000.

The weight average molecular weight of the polymaleic acid and its salt is preferably 500 to 10,000, particularly preferably 500 to 5,000.

The acrylic acid-maleic acid copolymer and its salt are copolymers or other water-soluble salts thereof with other monomers copolymerizable with maleic anhydride, and preferably have a structure represented by the following general formula (II).

Wherein R ³ , R ⁴ , R ⁵ and R ⁶ represent a hydrogen atom, an alkyl or alkoxy group having 1 to 5 carbon atoms, a phenyl group or a carboxyl group, M is a hydrogen atom, an alkali metal or an organic amine, x / y (molar ratio) = 1/10 to 10/1, and the average molecular weight is 1,000 to 100,000.

In the general formula (II), x / y (molar ratio) is 1/10 to 10/1, preferably 3/7 to 7/3. The weight average molecular weight of the acrylic acid-maleic acid copolymer represented by the formula (II) and its salt is 1,000 to 100,000, preferably 1,000 to 20,000.

The weight average molecular weight of the polycarboxylic acid polymer is measured by a gel permeation chromatography method (GPC method) using polyethylene glycol having a known molecular weight as a standard material.

The liquid detergent composition of the present invention preferably contains the component (C) in an amount of from 1 to 10% by weight, more preferably from 2 to 9% by weight, and still more preferably from 4 to 8% by weight, from the viewpoints of washing power and stability .

In the liquid detergent composition of the present invention, the weight ratio of the component (B) and the component (C) is preferably 1 to 10, more preferably 1 to 10, in terms of the cleaning power and stability To 5, and more preferably 1 to 3.

<Other components>

The liquid detergent composition of the present invention is a liquid detergent composition which comprises (D) a polyhydric alcohol other than the component (A) [hereinafter referred to as component (D)], and (E) (E) / (D) is preferably from 0.05 to 0.25, and more preferably from 0.1 to 0.25.

By using the component (D) and the component (E), it is possible to adjust the pH of the liquid cleaning force and reduce the slippery while maintaining the cleaning power.

The component (D) is preferably a polyhydric alcohol having 3 to 20 carbon atoms, more preferably 3 to 6 carbon atoms. The number of hydroxyl groups is preferably 3 to 8, more preferably 3 to 6. The content of the component (D) in the composition is preferably from 1 to 30% by weight, more preferably from 3 to 28% by weight, still more preferably from 5 to 15% by weight, from the viewpoints of cleaning performance, And particularly preferably 7 to 13% by weight.

Examples of the component (D) include aliphatic triols such as alkanetriols such as glycerin, trimethylol propane, trimethylol ethane and hexanetriol, aliphatic polyols such as pentaerythritol, sorbitol, mannitol, sorbitan , Diglycerin and dipentaerythritol, and their intramolecular or intermolecular dehydrates of alkanetriol, and saccharides such as sucrose, glucose, mannose, fructose and methyl glucoside. Preferred are ethylene glycol, propylene glycol, glycerin, sorbitol, mannitol, and glucose.

The content of the component (E) in the composition is preferably 0.05 to 2% by weight, more preferably 0.1 to 1.5% by weight, still more preferably 0.15 to 1% by weight, and particularly preferably 0.2 to 0.8% And most preferably 0.2 to 0.4% by weight. Examples of the component (E) include at least one compound selected from boric acid, borax and borate. Examples of the borate include sodium borate, potassium borate, ammonium borate, sodium tetraborate, potassium tetraborate and ammonium tetraborate.

Examples of optional components that can be incorporated into the liquid detergent composition of the present invention include polyethylene glycol [excluded as component (D)], re-pollution inhibitor such as carboxymethyl cellulose; Enzymes such as protease, amylase, lipase, and cellulase; Enzyme stabilizers such as calcium chloride; Lower alcohols such as ethanol; Lower alkylbenzenesulfonic acid salts such as benzenesulfonic acid salt and p-toluenesulfonic acid salt; Glycols such as propylene glycol; Solubilizing agents such as benzoic acid salts and urea; antioxidants such as t-butylhydroxytoluene and distyrylated cresol; And other antibacterial agents. It is preferable that the composition of the present invention does not contain a fluorescent dye, a bluing agent, a perfume, and a phosphate as a builder, but it may be blended if necessary.

The liquid detergent composition of the present invention is preferably a transparent composition, particularly a transparent aqueous solution, from the viewpoints of easiness of identification by appearance and beauty of appearance. Here, transparency means that the transparency is uniform and no turbidity when observed with the naked eye, but when a measuring instrument is used, the transmittance is usually 90% or more, preferably 95% or more, more preferably 98% or more . The transmittance was measured using a quartz cell with a "U-2000A Spectrophotometer" (spectrophotometer, manufactured by HITACHI) and measuring the transmittance of purified water at 600 nm as 100%. Normally, observation or measurement is performed at 20 □. The liquid detergent composition of the present invention preferably maintains a transparent state in the entire range of 0 to 40 占. The composition of the present invention contains 5 to 20% by weight of the component (A) and 10 to 30% by weight of the component (B), and the weight ratio of (A) / (B) is 0.2 to 1, It is necessary because it brings high cleaning performance. The content of the component (A) is preferably from 5 to 15% by weight, more preferably from 5 to 10% by weight, the content of the component (B) is from 10 to 25% by weight, And the weight ratio of (A) / (B) is 0.33 to 1, more preferably 0.33 to 0.7.

The liquid detergent composition of the present invention contains water of components (A), (B), (C) and (F).

The content of the component (F) is preferably 30 to 80% by weight, and more preferably 30 to 60% by weight. (B) / (F)) of the hydroxycarboxylic acid type chelating agent (B) and water (F) is preferably 10/90 to 35/65, more preferably 15/85 to 30 / 70 is more preferable.

The liquid detergent composition of the present invention has a pH (20 ° C) of 7.6 to 9, more preferably 7.6 to 8.5, and particularly preferably 7.7 to 8 in terms of hypoallergenic properties.

The liquid detergent composition of the present invention preferably has a pH (20 DEG C) elevated by water dilution from the viewpoint of detergency, and the pH (20 DEG C) at a dilution of 1,000 times with water (20 DEG C). The difference in pH (20 캜) between the stock solution and the 1000-fold dilution is preferably 0.1 to 2.0, more preferably 0.3 to 1.5.

(PH at use temperature, preferably pH at 20 占 폚) at the time of use (dilution with water at 200 to 5000 times, particularly at 1000 times dilution or 3000 times dilution with volume) Is more than 8.5 and less than 10, and more preferably 9 or more and less than 10, in particular, as an aqueous solution. The pH at the time of use may be attained by the dilution with water or may be attained by appropriately adjusting the pH, whichever may be, but it is preferable that the above range is attained by dilution with water .

The cleaning liquid preferably contains 0.001 to 0.1% by weight, more preferably 0.0015 to 0.05% by weight of the component (A), 0.002 to 0.5% by weight, more preferably 0.003 to 0.1% by weight of the component (B) ) Component in an amount of 0.0002 to 0.05% by weight, more preferably 0.0003 to 0.03% by weight, and the pH is preferably achieved in a diluted solution of that concentration.

The method of adjusting the liquid detergent composition of the present invention is not particularly limited. For example, the components (A) and (C) to (E) may be mixed and then the component (B) may be added and finally adjusted to a desired pH with an alkaline agent such as KOH or NaOH. Purified water is added as a diluent of components (A) and (C) or added at the end so that the total amount is 100 parts. In order to adjust the liquid detergent composition of the present invention to a desired viscosity, a solvent such as propylene glycol may be added.

The liquid detergent composition of the present invention is highly suitable for fiber products and is particularly suitable for medical use. It is also suitable for cleaning baby products. Examples of infant textile products include medical care, diapers, bedding, and the like.

When the liquid detergent composition of the present invention is used, it can be used not only for cleaning using a conventional washing machine but also for immersion cleaning using a base, a bucket, or the like. In case of pollution such as manure unevenness, it is particularly effective to wash with a washing machine after soaking for 2 to 3 hours.

(Medical stain decontamination method)

The method of decontamination of stains according to the present invention comprises (A) 5 to 20% by weight of an alkyl glycoside, (B) 10 to 30% by weight of a hydroxycarboxylic acid type chelating agent, and (C) a polycarboxylic acid type chelating agent (A) / (B) weight ratio of from 0.2 to 1 and (B) / (C) weight ratio of from 1 to 10, , Stool, and urine.

In order to remove contaminants, the liquid detergent composition of the present invention is preferably diluted (by volume) to 200 to 5000 times, more preferably 1000 to 3000 times, by using water such as tap water used in ordinary households desirable.

The pH at the time of contact is preferably more than pH 8.5 and less than 10, and the temperature at the time of contact is preferably 5 to 45 ° C, more preferably 10 to 35 ° C (liquid temperature) , It may be soaked for 2 to 3 hours or washed with a washing machine.

According to the present invention, it is possible to provide a liquid detergent composition which is hypoallergenic, excellent in appearance and excellent in stability without remarkable relief of irritation and damage to skin, hair or cloth, excellent in detergency and no stiffness due to cumulative cleaning / RTI &gt;

The following examples illustrate the practice of the present invention. The examples are illustrative of the present invention and are not intended to limit the present invention.

The liquid detergent composition of Table 1 was prepared and evaluated for cleaning properties (stain contamination, general contamination), texture of the undiluted solution, stiffness of the cleaning towel, storage stability, and appearance by the following methods. The results are shown in Table 1. The amount of each component in Table 1 is a net conversion value.

&Lt; Preparation of liquid detergent composition of Example 1 >

25 parts by weight of Myrod 12 (40% by weight aqueous solution), 20 parts by weight of oligomer D (40% by weight aqueous solution), 7.5 parts by weight of sorbitol, 1.5 parts by weight of boric acid and 3 parts by weight of propylene glycol, , 23.7 parts by weight of KOH (48 wt% aqueous solution) was added to adjust the pH of the stock solution to 9.0, and finally 3.3 parts by weight of purified water was added so that the total amount was 100 parts by weight. All adjustments of the mixing formulation were carried out at room temperature. Examples 2 to 6 and Comparative Examples 1 to 13 were conducted in the same manner.

(1) cleanliness

ㆍ Cleanliness 1 (stain contamination)

, And 0.4 mL of a 0.06% by weight chloroform solution of baryvin (manufactured by Wako Pure Chemical Industries, Ltd.), which is a major component of the bile pigment, was added to cotton buds (8 cm x 8 cm) to prepare stain stains. Respectively.

The liquid detergent composition shown in Table 1 was diluted 1000 times with 4 times light water (0.5 mL / 500 mL hard water, pH is shown in Table 1) Thereafter, water was rinsed with tap water. The reflectance of the non-lilvin-contaminated cloth before and after the cleaning was measured (measurement wavelength: 460 nm), and the cleaning rate was calculated by the following equation, and the average of the four cleaning ratios was evaluated by the following criteria.

Regarding cleaning property 1 (stain contamination), in the evaluation by the above method, it was judged that the cleaning rate of 40% or more was very good.

ㆍ Cleanliness 2 (general pollution)

EMPA 101 (carbon black / olive oil), manufactured by Swiss Federal Laboratories for Materials Testing and Research, The liquid detergent composition shown in Table 1 was diluted 3000 times with a 4-degree light water reactor (0.33 mL / 1 L water hardness), and the above-mentioned general contaminated contaminated cloths were cleaned with a cleaning tester at 85 rpm, a cleaning time of 10 minutes, By rinsing with water for 5 minutes. The cleaning rate (average of four sheets) was calculated in the same manner as the cleaning property 1, by measuring the reflectance of the general contaminated cloth before and after cleaning (measurement wavelength: 460 nm). Regarding cleaning property 2 (general contamination), in the evaluation by the above method, it was judged that the cleaning rate was 8% or more.

(2) Evaluation of texture of raw liquid

The liquid of the liquid detergent composition was applied to the fingertip, and after 30 seconds, it was rinsed with water. Sensory evaluation was carried out by five panelists on the slip of the fingertips, stimulation and the like.

○: All of the five people immediately felt slippery and did not feel any irritation.

[Delta]: There was a feeling that the long sticking remained for one or two people. Or stimulation.

X: There was a feeling that the slipperiness remained long for three or more persons. Or stimulation.

(3) Stiffness evaluation

Ten towels were cumulatively washed 10 times by a washing machine, and the flexibility of the towels after washing was evaluated by sensory evaluation using five panelists. Washing in a washing machine was carried out by 10 mL of the liquid detergent composition dissolved in 30 L of tap water, washing 10 times at a liquid temperature of 20 캜, and rinsing 3 times for 1 cycle. Further, the pH of the liquid detergent composition of the examples at both this dilution concentration and temperature was more than 8.5 and less than 10.

○: All five persons did not particularly feel stiffness.

△: 1 to 2 people felt stiffness.

X: More than three persons felt stiffness.

(4) Storage stability

90 g of the liquid detergent composition shown in Table 1 was put into a sample bottle (100 mL) made of glass, and the lid was closed and stored at 0 캜 and 40 캜 for 3 weeks, and the presence or absence of clouding, separation and precipitation was visually observed at 20 캜 . The evaluation criteria are as follows.

?: No whitening, separation, and precipitation occurred, and the appearance was transparent

?: No separation and precipitation occurred but cloudy, and the appearance was opaque

X: At least one of separation and precipitation occurred

(5) Appearance

90 g of the liquid detergent composition shown in Table 1 was put into a sample bottle (100 mL) made of glass, and the lid was closed and allowed to stand at 20 캜 for one day, and the presence or absence of clouding, separation and precipitation was visually observed at 20 캜 . The evaluation criteria are as follows.

○: No whitening, separation and precipitation occurred, and the appearance was transparent

[Delta]: Although neither separation nor sedimentation occurs, it is opaque and appearance is opaque

X: At least one of separation and precipitation occurred

* 1 Maidol 12, manufactured by Cao Corporation

* 2 Maidol 10, manufactured by Kao Corporation

* 3 on Margen 120, manufactured by Cao Corporation

* 4E Maru 270J, manufactured by Cao Corporation

* 5 Oligomer D, manufactured by Kao Corporation, weight average molecular weight: about 8,000

* 6 Poise 521, manufactured by Kao Corporation, weight average molecular weight: about 10000

Claims (8)

(C) a polycarboxylic acid type chelating agent in an amount of 1 to 10% by weight, (D) a compound having a carbon number of 1 to 10, (A) / (B) weight ratio is 0.2 to 1, and the weight ratio of the polyhydric alcohol is 3 to 20, the polyhydric alcohol having 3 to 8 hydroxyl groups is 1 to 30 wt%, and the water (F) (B) / (C) a weight ratio of from 1 to 10. The method according to claim 1, (E) a liquid detergent composition containing boric acid and / or a salt thereof capable of reacting with the polyhydric alcohol (D) and having a weight ratio of (E) / (D) of 0.05 to 0.25, Wherein the component (E) is at least one selected from the group consisting of boric acid, borax, sodium borate, potassium borate, ammonium borate, sodium tetraborate, potassium tetraborate and ammonium tetraborate. 3. The method according to claim 1 or 2, Wherein the component (A) is an alkyl glycoside represented by the following general formula (I). R^One(OR²)_pG_q (I) (Wherein R ¹ represents an alkyl or alkenyl group having 8 to 18 carbon atoms in the linear or branched chain or an alkyl (having 2 to 12 carbon atoms) phenyl group, R ² represents an alkylene group having 2 to 4 carbon atoms, G represents Is a residue derived from a reducing sugar (sugar) having 5 to 6 carbon atoms, and p has an average value of 0 to 5. q has an average value of 1 to 10.] 3. The method according to claim 1 or 2, Wherein the pH of the stock solution (20 DEG C) is 7.6 to 9.0. 3. The method according to claim 1 or 2, Wherein the pH (20 占 폚) at 1000 times dilution is higher than the pH (20 占 폚) of the stock solution and the pH (20 占 폚) at 1000 times dilution is more than 8.5 and less than 10. 3. The method according to claim 1 or 2, Transparent liquid detergent composition. A method for removing stains on a medical care, wherein the liquid detergent composition according to claim 1 or 2 is in contact with medical treatment (clothes). Use of the liquid detergent composition according to claims 1 or 2 for medical use (for clothing).