KR101351467B1 - Mixed-type Personal Care Product for Skin or Hair - Google Patents

Abstract

The present invention relates to a personal care product that imparts cosmetic conditioning effects such as softness, moistness, smoothness, and elasticity to hair or skin, wherein each product comprises a non-aqueous part containing no water and an aqueous part containing water. It is a product of the form that separates and stores the part of, and mixes immediately before use, the non-aqueous part is characterized in that it comprises a conditioning component having a functional group capable of covalently bonded to protein residues on the hair and / or skin surface do. The skin or hair personal care product of the present invention prevents the functional group activity of the conditioning component from deteriorating, and not only has excellent stability over time, but also semi-permanently maintains the conditioning effect on hair and skin.

Personal Care, Conditioning, Non-Aqueous, Aqueous, Mixed, Covalent, Functional

Description

Mixed-type Personal Care Product for Skin or Hair}

The present invention relates to a personal care product that provides cosmetic conditioning effects such as softness, moistness, smoothness, and elasticity to hair or skin, and more particularly, a personal care product that can impart semi-permanent conditioning effect to skin or hair. It is about.

A skin or hair personal care product is a product that provides a cosmetically beneficial condition for hair or skin such as softness, moistness, smoothness, elasticity, etc., and may further include functions such as cleansing and washing. Various methods for increasing the conditioning effect of personal care products have been studied steadily, but even if the conditioning effect is excellent, it is mostly one-time.

Therefore, studies are being actively conducted to keep the conditioning effect on the skin or hair not only one-time but semipermanently.

Japanese Laid-Open Patent Publication No. 2004-182731 discloses a cosmetic containing a conditioning component having a functional group which makes a covalent bond with the hair or skin surface, and Japanese Laid-Open Patent Publication No. 2001-513804 discloses a method of reducing disulfide bonds in hair. The following article discloses a product for covalently fixing a conditioning active compound. Korean Patent Publication No. 10-2006-0035343 discloses that a polyethylene glycol derivative, a conditioning component, is covalently bonded to cystine or an amine of hair, thereby enclosing the surface of the hair with a polymer layer, thereby increasing the thickness of the entire hair and having positive properties of the polymer. It is disclosed to semi-permanent hair coating composition is not a one-time delivery to the hair.

However, in the case of a conditioning component comprising a functional group capable of covalent bonding with skin and / or hair, it is necessary to control the moisture to maintain the activity of the functional group. That is, when the personal care composition containing the conditioning component including a functional group capable of covalent bonding with the skin and / or hair includes water, the functional group reaction activity of the conditioning component decreases with time, and thus, Constraints are applied. In addition, due to the water contained in the personal care composition must be kept in a container at all times airtight, there is inconvenience in carrying and using.

Therefore, the technical problem to be achieved by the present invention is to provide a personal care product for skin or hair that not only has excellent stability over time, but also lasts forever.

In order to achieve the above technical problem, the present invention is separated into a non-aqueous part and an aqueous part, the product used by mixing immediately before use, the non-aqueous part functional group capable of covalently bonded to protein residues on the hair or skin surface It provides a personal care product for skin or hair comprising a conditioning ingredient having a.

Preferably, the present invention provides a personal care product for skin or hair, characterized in that the conditioning component is a copolymer comprising an ethylene glycol monomer unit and a propylene glycol monomer unit in the personal care product, more preferably, It provides a personal care product for skin or hair, characterized in that the conditioning component has a hydroxysuccinimidyl ester as a functional group capable of covalently bonding with a protein residue.

Preferably, the present invention provides a skin or skin characterized in that the conditioning component comprises at least two, more preferably four or six functional groups capable of covalently binding to protein residues on the hair or skin surface. Provides a personal care product for hair.

Preferably, the present invention provides a personal care product for skin or hair, characterized in that the aqueous part of the personal care product comprises a material having a functional group capable of covalently bonding with the functional component of the conditioning component contained in the non-aqueous part, More preferably, the material having a functional group capable of covalent bonding with the functional group of the conditioning component included in the non-aqueous part is a copolymer for skin or hair, characterized in that the copolymer comprising an ethylene glycol monomer unit and a propylene glycol monomer unit having an amine group. Provide care products.

Hereinafter, the personal care product for skin or hair of the present invention will be described in more detail.

The present invention is separated into a non-aqueous part containing no water and an aqueous part containing water, which is used to mix immediately before use, wherein the non-aqueous parts can be covalently bonded to protein residues on the hair or skin surface It provides a skin or hair personal care product comprising a conditioning component having a functional group.

The conditioning component of hair or skin used in the personal care product of the present invention has a functional group capable of covalently binding to protein residues on the surface of the hair or skin. As disclosed in Korean Patent Laid-Open Publication No. 10-2006-0035343, hair or skin proteins have reactive residues such as thiol, hydroxyl, carboxyl, amine, and the like. Residues of these proteins may form covalent bonds with the functional groups of the conditioning component.

Such functional groups that can covalently bond with protein residues on the skin or hair surface included in the conditioning component include carbonate, aldehyde, propionaldehyde, butylaldehyde, and nitrophenyl carbonate. , Aziridine, isocyanate, thiocyanate, epoxide, tresylate, succinimide, hydroxysuccinimidyl ester, already Imidazole, oxycarbonylamidazole, imine, thiol, maleimide, vinylsulfone, ethyleneimine, thioether, acryl Functional group represented by acrylonitrile, acrylic acid or methacrylic ester, disulfide, ketone, RX ( R is any one selected from the group consisting of alkyl, aryl, aralkyl, ring and unsaturated ring, X is I, Br or Cl). An example of the reaction between a protein residue and a polymer having a functional group is illustrated in Schemes 1-12 of Korean Patent Application Publication No. 10-2006-0035343, which is incorporated herein by reference.

Preferably, such functional groups are included in two or more, more preferably four or six, plural in the conditioning component, and two or more kinds of functional groups may be included. For example, two, four or six hydroxysuccimidyl ester functional groups described below may be included in the conditioning component.

As such a conditioning component, a copolymer including an ethylene glycol monomer unit and a propylene glycol monomer unit is particularly preferable, and such conditioning component may be usefully used to impart a continuous moisturizing effect and oiliness to hair or skin. In the case of polyethylene glycol composed only of ethylene glycol monomer units, it has an excellent moisturizing effect but is poor in imparting oily feeling that shows a conditioning effect. The conditioning component in which the propylene glycol monomer unit is introduced into the polymer together with the ethylene glycol monomer unit can provide a moisturizing effect and oiliness at the same time. Copolymers comprising propylene glycol monomer units and ethylene glycol monomer units can be in block, crossover, graft, dendrimer, multibranched, or combinations thereof, so long as the purpose of imparting a moisturizing effect and oiliness is not impaired. Other monomers can be further copolymerized. The average molecular weight of the propylene glycol monomer unit and the ethylene glycol monomer unit in the copolymer is preferably 200 to 200,000, but is not limited thereto. The copolymer has a functional group capable of covalent bonding with protein residues on the surface of hair or skin.

In addition, when the conditioning component which is a copolymer comprising the ethylene glycol monomer unit and the propylene glycol monomer unit contained in the non-aqueous part of the present invention has a hydroxysuccimidyl ester functional group, the aqueous part of the product of the present invention is the hydroxysuccinate. Including a copolymer having a functional group that selectively reacts with a midyl ester functional group, more preferably an ethylene glycol monomer unit having an amine function and a propylene glycol monomer unit, forms a network structure on the hair and skin surface. As a result, stronger covalent bonds are formed and the effects can be sustained. In addition, by adjusting the composition, concentration and reaction conditions between the two conditioning components contained in the non-aqueous part and the aqueous part, respectively, it is possible to adjust the crosslinking point of the network structure so as to be convenient for use as a personal care product.

Conditioning ingredients of the hair or skin used in the personal care products of the present invention can be used as long as they can impart a cosmetically beneficial conditioning effect to the hair or skin. Such conditioning effects include washing, trimming, protection, Blocking, moisturizing, dyeing, coloring, discoloration, restriction, deodorization, antiseptic, cooling, hair removal, hair growth, hair loss prevention, wool, anti-inflammatory, reverb, aroma, whitening, anti-aging, wrinkle improvement, convergence, relaxation, shrinkage, sebum control, Keratin exfoliation, antiseptic, anti-inflammatory, ginseng, deodorant, antihistamine, anti-seborrhea, blood circulation promotion, UV protection, skin metabolism promotion. Such cosmetically beneficial conditioning ingredients include oily or oily materials such as silicones, fats and oils, waxes, hydrocarbons, higher fatty acids, higher alcohols and ester oils; Surfactants used for the purpose of emulsion solubilization; Polymer compounds used for moisturizing, thickening, and film formation; Ultraviolet absorber; Antioxidants; Metal ion sequestrants; Color materials such as dyes and pigments; Medicines such as vitamins, animal and plant extracts, hormones, enzymes, amino acids, peptides, proteins and the like; Spices; Dye derivatives; Sunscreen ingredients; sugars; antiseptic; Or components in a combination thereof .

The skin or hair personal care product of the present invention preferably contains 0.01 wt% to 90 wt% of the active substance having a functional group covalently bound to the protein residues of the hair or skin, relative to the total weight of the product.

The non-aqueous part of the personal care product of the present invention is in a form not in direct contact with water, and in the case of a solid tablet, capsule or powder, an active substance, a disintegrant, which can covalently bond with hair and / or skin, Foaming agents, binders, excipients, other auxiliary ingredients and the like.

In the personal care product of the present invention, a form dissolved or suspended in a liquid except for water, which is one of several forms of non-aqueous parts, has the viscosity of an active substance capable of covalently binding to hair and / or skin and a solvent and a stock solution except water. It is composed of a thickening component for control, and other auxiliary components, and the solvent used in this case may be a polyol such as ethylene glycol, propylene glycol, butylene glycol, glycerin, ethanol, and the like, which can be mixed with water, but is not limited thereto. It is not.

The other of the various forms of non-aqueous parts of the personal care products of the present invention is a water insoluble support; And a non-flowable carrier including a conditioning component of the non-aqueous part and supported on a water-insoluble support. As a method of supporting the powder, the conditioning component may be dissolved or dispersed in a liquid such as water and then sprayed onto the support to be dried, or a known supporting method such as printing, splashing, dipping or coating may be used. The non-flowable carrier supported on may be present in various non-flowable phases such as powder and film.

 The water-insoluble support may be in the form of a sheet or a patch and may be used as long as it can support a non-flowable carrier containing a conditioning component of hair or skin, for example, paper, fabric, nonwoven fabric, foam, Cotton and the like, but is not limited thereto.

The non-aqueous part of the present invention mainly cleans not only the conditioning component, but also other components that do not impair the object of the present invention as necessary, for example, anionic surfactants or fatty acid soap components in order to impart detergency to a personal care product. It can be added further as a component.

The personal care product of the present invention includes an aqueous part used as a solvent for dissolving the non-aqueous part immediately before use, and preferably, the aqueous part includes a functional group that selectively reacts with a functional group of the conditioning component included in the non-aqueous part. Material, water, acid to adjust pH, base ingredient, thickening ingredient to adjust viscosity of stock solution, conditioning ingredient effective to hair and skin and catalyst, chelate ingredient, preservative, fragrance, fragrance or oily conditioning ingredient to increase reactivity It may contain conventional ingredients that can be included in water-soluble preparations for use in the skin and / or hair, such as surfactants for dissolving or solubilizing.

Additives that may be added to the non-aqueous parts and the aqueous parts of the personal care products of the present invention include, in addition to the cleaning components described above, fixative polymers, thickeners, anionic, nonionic, cationic or amphoteric surfactants, perfumes, preservatives, Sunscreen. Protein, vitamins, provitamins, anionic, nonionic, cationic or amphoteric polymers, mineral, vegetable or synthetic oils, ceramides, pseudoceramides, linear or cyclic, modified or unmodified Nonvolatile silicones, pH regulators, oxidants. Components applicable to hair or skin, such as reducing agents, inhibitors, and catalysts, can be added within a range not impairing the object of the present invention.

The personal care product according to the present invention is applied to hair or skin by moistening before use, wherein the functional group of the conditioning ingredient reacts with the hair or skin to impart a semi-permanent conditioning effect. Thus, the conditioning ingredients combined with hair or skin do not fall off during normal cleaning due to shampoos, detergents, soaps and the like and can remain attached to hair and skin almost permanently.

Hereinafter, the present invention will be described in more detail with reference to examples. However, embodiments according to the present invention may be modified in many different forms, and the scope of the present invention should not be construed as being limited by the embodiments described below. Embodiments of the invention are provided to more fully describe the present invention to those skilled in the art.

≪ Preparation of Examples and Comparative Examples >

To prepare a non-aqueous personal care composition in the composition and content shown in Table 1. In the case of Example 1, the raw materials shown in Table 1 were mixed in a powder state, and tablets of 20 mm in diameter, 4 mm in thickness, and 2.5 g in weight were made using a tableting machine, and in Example 2, these compositions were simply mixed in powder form. Prepared. In the case of Examples 3 to 5, the mixture was mixed with the indicated composition and stirred for 10 minutes to prepare a liquid phase, and Example 6 was first added PEG / PPG copolymer derivative to butylene glycol and stirred for 10 minutes, followed by sheet into the liquid phase. It was prepared by loading on. The sheet used in Example 6 was prepared in the form of a nonwoven fabric.

In the case of Comparative Example 1, the mixture was prepared by stirring with water for 10 minutes, and in Comparative Example 2, it was prepared by supporting it on a sheet.

Raw material name Example Comparative Example One 2 3 4 5 6 One 2 water 90 90 PEG-400 90 glycerin 90 Butylene Glycol (1,3-BG) 90 90 4-PEG / PPG (800/200) Block Copolymer-hydroxysuccinimidyl ester 10 100 10 10 10 10 10 10 NaHC0 ₃ 50 - - - - - - - Citric acid 20 - - - - - - - Sorbitol granules 20 - - - - - - - Formulation refine powder Liquid Liquid Liquid Sheet Liquid Sheet

In Table 1, PEG / PPG (800/200) represents copolymers having an average molecular weight of 800 and 200, respectively, of an ethylene glycol monomer unit and a propylene glycol monomer unit.

<Evaluation of Examples and Comparative Examples>

Example 1-6 and Comparative Example 1-2 prepared by the above production method was stored for 25 days at 25 degrees Celsius 55% relative humidity state for one week and in the aqueous solution prepared in the composition of Table 2 in the case of Example 1 10 For example, Example 2, 2.5g of powder, Example 3-5 and 50g for Comparative Example 1 was added to 50g of the following Table 2 aqueous solution of pH 9 and Example 6 and Comparative Example 2 the sheet of Table 2 50 g of an aqueous solution was used as it was. In each case, treatment was performed on the hair skein to evaluate the moisturizing persistence to evaluate whether the activity of the reactor reacting to the hair and the skin was decreased.

Raw material Content (% by weight) water Input to 100 4-PEG / PPG (800/200) Block Copolymer-Amine One Sodium Phosphate Dibasic 0.4 Polyquaternium-10 0.5 PEG 400 1.0 Hydrolyzed Wheat Protein 1.0 Methylchloroisothiazolinone Methylisothiazolinone 0.01

Moisturizing Duration Evaluation

For the personal care products of Examples 1-6 and Comparative Examples 1-2, the hair holding force of 20 cm in length and 10 g in weight was measured while the hair was dried after shampooing. The hairdresser prepared first was washed with 5% sodium lauroyl sulfate solution and dried. Example 1-6 and Comparative Example 1-2 product was treated with a hairtress for 10 minutes and then washed in running water. This was washed, rinsed, and dried five times with 10% sodium lauroyl sulfate solution and dried with a towel to add a weight of tress and water to a total of about 13 g. Put this hairtress on the scale at 25 degrees Celsius, 55% relative humidity and measure the weight change after 12 hours as moisturizing rate (%) = ((later weight-initial weight) / initial weight) × 100 to check the moisturizing effect. The results are shown in Table 3 below.

Initial weight Weight later Later Weight-Initial Weight Moisturizing rate (%) Example 1 10.00 10.30 0.30 3.00 Example 2 10.00 10.34 0.34 3.40 Example 3 10.00 10.18 0.18 1.80 Example 4 10.00 10.24 0.24 2.40 Example 5 10.00 10.23 0.23 2.30 Example 6 10.00 10.17 0.17 1.70 Comparative Example 1 10.00 10.03 0.03 0.30 Comparative Example 2 10.00 10.05 0.05 0.50

As shown in Table 3, the hair treated with the product of Examples 1-6 stored in a dried state or in a form not in contact with moisture was treated with the product of Comparative Example 1-2 stored in direct contact with moisture. It was evaluated to have excellent moisturizing power compared to hair. The difference in the moisturizing rate of the products according to the embodiment is determined by the degree of moisture indirectly contacted depending on the formulation. As a result, the product of Example 1-6 was confirmed that a strong bond is formed to maintain a continuous moisturizing power even in the cleaning.

As described above, the skin or hair personal care product according to the present invention does not include water because the non-aqueous part does not include water, thereby covalently binding to protein residues on the hair or skin surface to give the hair or skin a continuous and good conditioning effect. It is possible to prevent the deterioration of the functional groups contained in the components, so that the stability over time is excellent, and the conditioning effect on the hair and the skin can be permanently maintained. In particular, when a copolymer including an ethylene glycol monomer unit and a propylene glycol monomer unit is used as a conditioning component, more preferably, when the copolymer has a hydroxysuccimidyl ester functional group, it can give a good moisturizing effect and oiliness at the same time. Can be.

Claims (9)

It is divided into non-aqueous parts and water-based parts, and is mixed and used just before use. The non-aqueous part includes a conditioning component having a functional group capable of covalently binding to protein residues on the hair or skin surface, The protein residue on the hair or skin surface is any one selected from the group consisting of thiol, hydroxyl, carboxyl and amine, The functional group capable of covalently binding to a protein residue on the hair or skin surface is carbonate, aldehyde, propionaldehyde, butylaldehyde, nitrophenyl carbonate, aziridine , Isocyanate, thiocyanate, epoxide, tresylate, succinimide, hydroxysuccinimidyl ester, imidazole, oxy Oxycarbonylamidazole, imine, thiol, maleimide, vinylsulfone, ethyleneimine, thioether, acrylonitrile, Functional groups represented by acrylic acid or methacrylic esters, disulfides, ketones and RX (R is alkyl, aryl, aralkyl, ring And any one selected from the group consisting of an unsaturated ring, X is characterized in that at least one selected from the group consisting of I, Br or Cl Im) Personal care products for skin or hair. The personal care product for skin or hair according to claim 1, wherein the conditioning component is a copolymer comprising an ethylene glycol monomer unit and a propylene glycol monomer unit. The method of claim 1, wherein the conditioning component is an oil or oil raw material which is silicone, oils, waxes, hydrocarbons, higher fatty acids, higher alcohols or ester oils; Surfactants for emulsifying solubilization; High molecular compounds used for the purpose of moisturizing, thickening or forming a film or themselves as powders; Ultraviolet absorber; Antioxidants; Metal ion sequestrants; Colorants which are dyes or pigments; Medicines that are vitamins, animal or plant extracts, hormones, enzymes, amino acids, peptides or proteins; Spices; Dye derivatives; Sunscreen ingredients; sugars; And preservatives, any one or more selected from the group consisting of skin or hair personal care products. delete delete The method of claim 1, wherein the non-aqueous part is a skin, characterized in that any one selected from the group consisting of tablets, capsules, powders, solutions, suspensions, gels and formulations supported on a water-insoluble support Personal care products for hair. The personal care product for skin or hair according to claim 1, wherein the conditioning component comprises two or more functional groups capable of covalently binding to protein residues on the hair or skin surface. The personal care product for skin or hair according to claim 1, wherein the aqueous part comprises a copolymer comprising an ethylene glycol monomer unit having an amine group and a propylene glycol monomer unit. delete