KR101229785B1 - Box for Sample Tube - Google Patents

Abstract

The present invention relates to a sample tube box in which an electronic tag is introduced to a sample tube box in which a sample tube used in the medical industry is stored, so that information related to the sample tube and the sample can be efficiently and integratedly managed.
The present invention is characterized in that it is configured by installing an electronic tag on one side of the box body of the sample tube box including a box body that is stored in the sample tube is stored inside the sample tube, the lid is opened and closed.

Description

Box for Sample Tube

The present invention relates to a sample tube box, and more particularly, an electronic tag is introduced into a sample tube box that stores a sample tube in which a sample used in the medical industry is stored, so that information related to the sample can be efficiently and integratedly managed. It relates to a sample tube box.

The medical sector, which is recognized as the next growth engine, can be summarized as personalized medicine, linkage of biomedical industry, popularization of U-Health, globalization of medical service and the spread of consumerism. In particular, in order to solve the challenges of human life and prolonged life, attention is focused on the treatment of intractable diseases, the development of new drugs, and the development of bio-artificial organs. In order to proceed efficiently, they are closely connected with the biomedical industry and information technology. .

New drug development consists of a research phase, a preclinical / clinical / production process development phase, approval and certification of candidate clinically completed candidates, and production and marketing of approved new drugs. Among them, preclinical and clinical stages are used to verify the effects or side effects of new drugs, which require long periods of time, many samples, and high costs. In particular, the acquisition of customized human samples (cells) for medical research and clinical trials has become a significant factor in the duration and cost.

Recognizing the importance of the above-mentioned human samples (hereinafter referred to as "samples"), domestic medical institutions and research institutes have organized tissue banks in each university hospital since the early 1990s to store samples for various cases. Since numerous samples are managed manually, it is impossible to systematically manage or link medical information.

In the conventional sample management system, the sample management method is as follows: A sample collected from a human body is placed in a sample container or a tube (hereinafter referred to as a "sample tube"), and then 50 to 100 sample tubes are usually prescribed. After storing in the sample tube box, store the sample tube box in a low or cryogenic storage facility. At this time, in order to distinguish the stored sample from other samples, write the control number or symbol (hereinafter referred to as "symbol") directly on the sample tube and the sample tube box, or attach it by recording it on the label. These sample information are managed by a database via a symbol.

In particular, when the sample tube box stored in the low temperature cold storage device or cryogenic freezing storage device is taken out, steam or frost occurs on the surface of the sample tube box due to temperature difference. Therefore, it is necessary to clean the surface to check the sign. This process is not only complicated, but the sign is erased or the label is separated from the sample tube box. In addition, when the contents are discolored or discolored when stored for a long time, it often becomes difficult to confirm the contents of the information.

In addition, in order to take out a sample tube box containing a desired sample tube from a storage device (for example, a low temperature refrigerator) containing a plurality of sample tube boxes, there was an inconvenience of having to take out the sample tube box inside.

In addition, since the marking on the sample tube box and storing the information according to this mark on a computer are all performed manually, there is a problem that the information of the sample stored in the sample tube box and the information of the computer do not match.

The present invention has been developed to solve the problems of the prior art, it is possible to prevent the information related to the stored sample tube is incorrectly input or damaged marks, and can provide more accurate information related to the sample tube An object of the present invention is to provide a sample tube box having a sample information label.

The present invention for achieving the above object relates to a tube storage box for providing a more accurate sample information to avoid damage to the information related to the sample tube, a plurality of sample tubes are stored therein There is a receiving space, characterized in that consisting of a box body provided with an electronic tag for storing information about the plurality of receiving sample tubes, and a box lid provided to be opened and closed on the box body.

In the sample tube box, a plurality of sample tubes are stored and stored, and an electronic tag installed in the sample tube box is read by a predetermined reader whenever necessary. In order to close the reader more easily to the electronic tag in this process and to prevent signal confusion with the electronic tag of the adjacent sample tube box, the electronic tag is preferably installed at the front center of the box body. The front of the box body means any one of the walls that are vertical when the sample tube box is stored or moved.

According to the present invention, the electronic tag is mounted on the box body in various ways to prevent the electronic tag from being damaged by moisture or falling off from the sample tube box during storage or use. For example, in the process of manufacturing the box body, there is a method of directly embedding the electronic tag on the wall surface of the box body, forming a tag installation groove on the front wall of the tube body and inserting the electronic tag therein. At this time, it is preferable to cover and heat seal the cover so that the electronic tag is not separated from the installation groove or the like, or to apply a sealing material such as a liquid epoxy resin.

On the other hand, the sample tube accommodated in the sample tube box as described above is in the form of a rod, can be tilted during storage / movement, in order to prevent this additionally installed support means for vertically supporting the sample tube inside the box body Good to do.

In addition, an electronic tag may be installed in the sample tube stored inside the tube sample tube box. That is, the sample tube box according to the present invention has a receiving space therein, the sample including a tube body provided with an electronic tag for storing information about the received sample, and a lid provided to be opened and closed on the tube body. It is preferable that the tube is accommodated. At this time, the location of the electronic tag installed in the sample tube is preferably the bottom center of the sample tube. In order to more easily recognize the electronic tag installed on the bottom of the sample tube, the bottom of the sample tube is preferably exposed to the outside. Accordingly, the bottom surface of the sample tube is exposed to the outside on the bottom of the box body. The through hole can be formed as much as possible.

The present invention, by using an electronic tag rather than an identification means such as a label that is easy to be damaged in order to identify a sample tube box in which a sample tube for storing a medical sample or the like is stored, the information of the sample is damaged by the damage of the identification means. The problem of misreading can be solved.

In addition, by reading the electronic tag with a tag reader to organize and manage the information of the sample tube stored in the sample tube box, not only can you manage accurate sample information corresponding to the sample stored in the sample tube, but also compute it according to the sample information. This has the effect of eliminating the hassle of typing on the device.

In addition, by managing the information about the sample information and the sample tube box by the electronic system through the electronic tag, it is possible to quickly and accurately check the sample history and provide it to the researcher, thereby drastically reducing the research period and cost of the medical / bio field. Will be.

1 is an exploded perspective view showing an example of a sample tube box according to the present invention;
Figure 2 is a partial cross-sectional perspective view showing an enlarged portion of the sample tube box shown in FIG.
3 is an exploded perspective view showing another example of a sample tube box according to the present invention;
4a to 6 is a perspective view showing another example of the installation structure for installing the electronic tag in the sample tube box of the present invention,
7A and 7B are sectional views showing a part of a sample tube box in which sample tubes are stored.

Hereinafter, the present invention will be described in more detail with reference to the accompanying drawings and examples. However, the drawings and the embodiments are only illustrative of the contents and scope of the technical idea of the present invention, and the technical scope of the present invention is not limited or changed. In addition, it will be apparent to those skilled in the art that various modifications and changes can be made within the scope of the present invention based on these examples.

The sample tube box 1 of the present invention, as shown in Figures 1 and 3, to more easily and accurately manage the information of the sample tube stored therein, the sample tube 10 is stored the sample Is composed of a box body 11 is stored, and the lid 12 is installed on the open side of the box body 11, the information about the sample tube 10 is stored on one side of the box body (11) Characterized in that the stored electronic tag (2) is installed.

As described above, the sample tube box 1 according to the present invention is a box in which the sample tube 10 in which the sample is stored is stored, and the sample tube box should be stored at a low temperature or cryogenic temperature (below -80 ° C). 1) should be made of a material that can withstand cryogenic temperatures (below -80 ℃). In addition, the horizontal section of the sample tube box (1) can be various, such as square or polygonal or round or oval, and can be produced in various sizes depending on the size or number of the sample tube 10 to be stored. In the open end (upper part) of the sample tube box 1, the lid 12 is provided to be opened and closed.

The box body 11 of the sample tube box 1 according to the present invention is provided with an electronic tag 2 as a means for storing various information about the sample tube 10 to be stored. The information stored in the electronic tag 2 may be a unique identification code consisting of numbers or letters or a history related to a sample. That is, all information related to the sample, such as the type of sample, the time of collection, the place of collection, the retention period can be stored.

When the electronic tag 2 is installed on the lid 12, when the lid 12 is changed, the electronic tag 2 has different information from the sample tube 10 stored in the box body 11, which may cause an error in the sample information. Therefore, the electronic tag 2 is preferably installed in the box body 11 as shown in Figs.

The sample tube box 1 is typically stored inside a freezer, such as a freezer. In order to easily recognize the electronic tag 2 even in the state stored in the freezing device, the side wall of the sample tube box 1 exposed to the outside in the open state of the freezing device, in particular, the front of the sample tube box 1. It is preferable to provide the electronic tag 2 in the installation.

There may be various methods of mounting / installing the electronic tag 2 on the box body 11. Some preferred examples thereof will be described with reference to the accompanying drawings.

2 illustrates an example in which the electronic tag 2 is integrally embedded in the center of the side wall of the box body 11. This configuration is made by injecting the electronic tag 2 and the box body 11 integrally in the process of manufacturing the box body 11 of the sample tube box 1, the electronic tag 2 is not exposed to the outside Waterproofness can be increased. However, the electronic tag 2 installed in this way may not be separated from the box body 11 and may be damaged by the high temperature applied during the injection process of the box body 11.

4A to 6, the tag mounting groove 111 is formed on the outer surface of the side wall of the box body 11, and the tag 2 is provided with the electronic tag 2. In this case, in order to prevent the electronic tag 2 from being separated from the installation groove 111, it is preferable to install the cover 3 or to apply the sealing material 4.

4a and 4b is that the cover 3 is detachably installed in the tag installation groove 111, Figure 5 is fused after installing the cover 3 in the tag installation groove 111, Figure 6 is a tag The example which apply | coated the sealing material 5 to the installation groove 111 is respectively shown.

As shown in FIGS. 4A and 5, the tag installation groove 111 is formed in an inwardly hollow shape on the outer surface of the side wall of the box body 11, or as shown in FIGS. 4B and 6. It can be made fine in the downward direction from an upper end. In addition, the lid 3 which blocks the tag installation groove 111 may be detachably installed as shown in FIGS. 4A and 4B, or may be fused to the main body 11 as shown in FIG. 5.

 When the cover 3 is detachably installed, as shown in FIGS. 4A and 4B, the cover fixing groove 112 is formed on the side wall of the tag installation groove 111, and the locking step 3a is disposed on the cover 3. ) So that the locking step 3a of the cover 3 is fitted into the cover fixing groove 112 to be fixed. The cover 3 is elastic, and the locking jaw 3a formed at one end of the cover is inserted into the cover fixing groove 112, and then the locking jaw 3a of the other end is inserted into the cover fixing groove 112 facing the cover by elasticity. (3) is unfolded to block the tag installation groove (111).

When the cover 3 is installed, as shown in FIG. 5, the electronic tag 2 may be inserted into the tag installation groove 111, and the cover 3 may be inserted into the installation groove 111 and then fused. .

In the case of applying the sealant 4 to the tag installation groove 111, as shown in FIG. 6, the sealant 4 is coated to an extent that can sufficiently cover the electronic tag 2, and then cured. As the sealant 4, a resin having a property of curing when exposed to the air, such as a liquid epoxy resin, may be used.

In the sample tube box 1 of the present invention configured as described above, a plurality of sample tubes 10 are stored / stored at regular intervals. At this time, it is preferable to be able to distinguish the inner sample tube 10 in the state accommodated in the sample tube box (1). Therefore, an electronic tag (not shown) may also be installed in the sample tube 10. In this case, it is preferable to install the electronic tag in the center of the bottom of the sample tube 10 in order to minimize interference between adjacent electronic tags.

As described above, in order to more easily detect the electronic tag of the sample tube 10 from the outside in the state in which the sample tube 10 having the electronic tag is installed in the sample tube box 1, It is preferable that the sample tube box 1 be configured so that the bottom portion is exposed to the outside. That is, as shown in Fig. 2, 7a and 7b, it is preferable to form a through hole 11a on the bottom surface of the box body 11 so that the lower end of the sample tube 10 is exposed to the outside. The electronic tag on the bottom surface of the sample tube 10 is exposed through the through-hole 11a to easily and accurately detect the electronic tag from the outside.

In addition, in order to prevent the sample tube 10 accommodated in the sample tube box 10 from tilting or falling, it is preferable to further install a supporting means for supporting the sample tube 10 inside the box body 11. For example, as illustrated in FIGS. 1 and 2, a plurality of tube through holes 13a are formed at regular intervals, and are configured in the shape of a perforated plate 13 that can be detached from the box body 11, or FIG. As shown in Fig. 3, a plurality of plates may be woven in the form of a lattice plate 4 in which the tube insertion grooves 14a are formed.

In the case of the perforated plate 13 as shown in FIGS. 1 and 2, the plate body portion must be kept at a distance from the bottom surface of the sample tube box 11 to support the middle portion of the sample tube 10. have. Therefore, the two edges of the perforated plate 13 which face each other are bent downward to form a support wing so that the distance between the bottom of the main body 11 and the perforated plate 13 is maintained by the support wing or the sample tube box 11. A support jaw (not shown) was formed on the inner wall of the perforated plate 13 so that it could be supported no longer falling down.

As shown in FIG. 3, when the supporting means is constituted by the grating plate 14, each plate constituting the grating plate 14 is perpendicular to the bottom of the sample tube box 11, and its height is greater than or equal to a predetermined height. By constructing, the sample tube 10 is supported not to be inclined by the plate.

In the sample tube box 1 according to the present invention as described above, RFID (Radio-Frequency IDentification) may be used as the electronic tag (2). Usually, RFID is composed of an IC chip on which various kinds of information are recorded, and an antenna for transmitting and receiving information with the outside. That is, the information transmitted through the antenna can be read by a reading means (hereinafter, referred to as a "tag reader"), and the sample information stored in the electronic tag 2 itself or the sample information corresponding thereto is separately a computer equipment such as a computer. (Hereinafter referred to as " computer ").

On the other hand, it is possible to build a medical sample management system for managing / utilizing the sample tube and the samples stored in the sample tube box 1 according to the present invention. The management system includes an electronic tag installed in the sample tube 10, the sample tube box 1 in which the sample tube 10 is stored, and the sample tube box 1 and / or the sample tube 10. It may include a tag reader (not shown) to recognize, and a sample information management device (not shown) for storing and managing the information of the electronic tag recognized by the tag reader.

At this time, the sample tube box (1) tag reader is a portable type is preferably manufactured to transmit and receive information remotely. Using this, even if the sample tube box 1 is stored in a freezing device such as a freezer or the like, a list of sample tubes 10 stored in the sample tube box 1 may be input or output, and a desired sample may be used. When the sample tube box 1 in which the tube 10 is stored is found, the marker provided on the sample tube 10 may be directly checked or the desired sample tube may be found by reading an electronic tag.

Of course, the sample tube box 1 is taken out and placed in another sample recognizer (not shown), and then the information of all the sample tubes 10 stored in the sample tube box 1 is collected by using a tag reader provided in the sample recognizer. You can also output

When the electronic tag of the sample tube box 1 or the sample tube 10 is RFID, the tag reader is configured with an RFID reader.

In addition, the sample information management device constituting the medical sample management system is preferably provided with a database for storing the sample information, as well as a program for managing the sample. The sample management program inputs and outputs the information of the stored sample tube or tube case and the samples stored in them, manages the access of the sample, and manages information about the environment of the cryogenic tank in which the sample is stored.

The present invention can be applied not only to the medical field, but also to the aerospace, defense, agricultural and marine products frozen distribution, natural resource development. In other words, when the sample is a medical history, the sample may be used as a material for medical research, and the history and history of the human sample may be determined. In other words, the site of human sample, sickness, medication record, and various test results are very clinically important factors and must be grasped to have value as a research sample for customized treatment.

The technology of the present invention can create new value through the convergence of medical, bio, and information technology.

By utilizing the ubiquitous network infrastructure for U-Health, the combination of medical and telematics is expected to create new value of medical information provision connected with Order Communication System (OCS), Electronic Medical Record (EMR), Picture Archiving and Communication System (PACS), etc. Can be.

In addition, it can be expected to have a ripple effect to similar industries by combining it with a special environment called cryogenic temperature.

By removing human cryogenic samples from cryogenic devices (less than -80 ℃) and recognizing them within seconds, it is easy to manage samples, and beyond the medical and new drug development, aerospace, defense, agricultural and fishery frozen distribution, and natural resource development. It can be applied to.

Moreover, the period and cost of medical / bio research can be drastically reduced.

New therapies and new drug development require long research periods with significant capital and cost. Especially in the clinical field, obtaining customized samples for many test materials and specific diseases is very important in terms of time and cost. Therefore, when the present invention is utilized nationwide, it will provide a breakthrough in acquiring samples required for research by sharing human sample information stored in medical institutions or research institutes, and thus will play a significant role in reducing the economics and duration of research.

In addition, the transparent management of human samples used in medical research can solve the fundamental problems of research quality and bioethics. In most medical studies, medical significance is measured by counting the number of clinically used samples and the number of effective samples. However, the strict management of these samples is not possible, and calculations based on the morality of the researcher are problematic for many distrusts and economics of the research results. The present invention can manage the access and flow of the sample to end the above problems and to control the objective data on the results of the research, such a sample management for the research may be able to end the expenditure for the results of the study worldwide. It is expected.

1: Sample tube box
11: box body 111: tag mounting groove 112: cover fixing groove
12: lid
13: perforated plate 13a: tube through hole
14: plate 14a: tube insertion groove
2: Electronic Tag
3: cover 3a: locking jaw
4: sealing material
10: sample tube

Claims (7)

There is an accommodating space for accommodating a plurality of sample tubes in which the sample is stored,
A box body provided with an electronic tag for storing information on the plurality of receiving sample tubes;
In the sample tube box comprising a box lid installed to open and close the box body,
Inside the box body is provided with a support means for vertically supporting the sample tube to be stored,
Sample tube box, characterized in that the through-hole is formed on the bottom of the box body to expose the bottom of the sample tube to be stored to the outside.
The method of claim 1,
The electronic tag is a sample tube box, characterized in that installed in the front center of the box body.
The method of claim 1,
The electronic tag is a sample tube box, characterized in that embedded in the center of the front wall of the box body.
The method of claim 1,
The electronic tag is inserted into the tag installation groove formed on the outer surface of the front wall of the box body sample tube box, characterized in that the cover is fused or filled with a sealing material.
delete delete The method according to any one of claims 1 to 4,
The sample tube, there is a receiving space for receiving a sample therein,
A tube body provided with an electronic tag for storing information on a received sample;
Sample tube box, characterized in that the sample tube consisting of a lid installed to open and close the tube body.

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