KR101012068B1 - Nanoporous carbon material comprising magnetic nanoparticles in nanopore and method for producing same - Google Patents

Abstract

Disclosed are the preparation of nanoporous carbon materials comprising nanoparticles having regularly arranged nanometer pores and showing magnetic properties in the pores and their application as adsorbents. The organic material precursor is used as a substance, and the nanoparticle precursor is a magnetic nanoparticle precursor. The transition metal compound is used to produce a carbon material containing nanoparticles having magnetic properties in the pores with a large surface area, nanometer-sized pores, and a regular pore arrangement. It was synthesized in the reaction vessel and showed excellent ability for adsorption of ibuprofen drug.

Nanoporous Carbon, Magnetic Materials, Nanoparticles, Synthesis, Ibuprofen, Adsorption, Pores

Description

Nanoporous carbon with magnetic nanoparticles in nanopores and one-pot manufacturing method of the materials

The present invention relates to a nanoporous carbon material comprising nanoparticles having nanometer-sized pores regularly arranged and magnetic in the pores, and a method of manufacturing the same.

More specifically, the use of terpolymers as templates, organic precursors as materials to form pore walls, and transition metal compounds as magnetic nanoparticle precursors, large surface area, nanometer size pores and regular pore arrangement The present invention relates to a technique for synthesizing a carbon material including nanoparticles having magnetic properties in pores in a single reaction vessel, which provides excellent ability for adsorption of ibuprofen drug.

Carbon materials with regular arrays and uniformly sized nanopores have high surface area (approximately 600 m 2 / g or more), high thermal stability, chemical inertness, hydrophobic surface, and stable hydrolysis resistance compared to silica, resulting in high applicability. ( B ) R. Ryoo, SH Joo and S. Jun, J. Phys . Chem . B , 1999, 103, 7743. (b) R. Ryoo, SH Joo, M. Kruk and M. Jaroniec, Adv . Mater . , 2001, 13, 677. (c) S. Jun, SH Joo, R. Ryoo, M. Kruk, M. Jaroniec, Z. Liu, T. Ohsuna and O. Terasaki, J. Am . Chem . Soc ., 2000, 122, 10712. ( d) SH Joo, SJ Choi, I. Oh, J. Kwak, Z. Liu, O. Terasaki and R. Ryoo, Nature, 2001, 412, 169. (e) SB Yoon , JY Kim and J.-S. Yu, Chem . Commun . , 2002, 1536. (f) A. Vinu, V. Murugesan, O. Tangermann and M. Hartmann, Chem . Mater ., 2004, 16, 3056. ).

Recently, it has shown high application potential in areas such as shape or size selective separation, chromatographic separation, catalysts, nanoscale reaction vessels, energy storage, capacitors, and biomedical devices ((a) K. Lu and DDL Chung, Carbon , 1997, 35, 427. (b) M. Hartmann, A. Vinu, G. Chandrasekar, Chem . Mater . 2005, 17, 829. (c) SH Joo, SJ Choi, I. Oh, J. Kwak, Z. Liu, O. Terasaki and R. Ryoo, Nature , 2001, 412, 169. (d) A. Vinu, C. Streb, V. Murugesan and M. Hartmann, J. Phys . Chem . B , 2003, 103, 7743. (e) A. Vinu, V. Murugesan and M. Hartmann, J. Phys . Chem . B , 2003, 108, 7323.).

These nanoporous carbon materials have been synthesized by many researchers. First, the nanoporous silica material used as a template is synthesized, and then various organic compounds (such as sucrose, perperyl alcohol, ethylene, acenaphthalene, phenol-formaldehyde, etc.) are filled in the nanopore, followed by carbonization. Prepared by removing silica using hydrofluoric acid or strong base solution ((a) R. Ryoo, SH Joo and S. Jun, J. Phys . Chem . B , 1999, 103, 7743. (b) S. Jun, SH Joo, R. Ryoo, M. Kruk, M. Jaroniec, Z. Liu, T. Ohsuna and O. Terasaki, J. Am . Chem . Soc . , 2000, 122, 10712. (c) J.-S. Lee, SH Joo and R. Ryoo, J. Am . Chem . Soc . , 2002, 124, 1156. (d) SH Joo, SJ Choi, I. Oh, J. Kwak, Z. Liu, O. Terasaki and R .. Ryoo, Nature, 2001, 412, 169. (e) W.-H. Zhang, C. Liang, H. Sun, Z. Shen, Y. Guan, P. Ying and C. Li, Adv. Mater, 2002, 14, 1776. (f) T.-W. Kim, I.-S. Park and R. Ryoo, Angew. Chem., Int. Ed., 2003, 42, 4375. (g) J. Lee, S. Yoon, T. Hyeon, SM Oh and KB Kim, Chem. Commun . , 1999, 2177.).

Also some researchers (Zhao et al ., Liang et al . S. Tanaka et al.) Use a double copolymer or a terpolymer as a template and do not use nanoporous silica materials and use a phenol-formaldehide precursor, Nanoporous carbon materials were synthesized by organo-organic self-assembly using synol-formaldehide or phloroglucinol-formaldehide followed by carbonization of the material ((a ) Y. Meng, D. Gu, F. Zhang, Y. Shi, H. Yang, Z. Li, C. Yu, B. Tu and D. Zhao, Angew . Chem . Int . Ed . , 2005, 44, 7053. (b) Y. Huang, H. Cai, T. Yu, X. Sun, B. Tu and D. Zhao, Chemistry-An Asian Journal, 2007, 2, 1282. (c) Y. Wan, Y. Shi and D. Zhao, Chem . Mater . , 2008, 20, 932. (d) S. Tanaka, Y. Katayama, MP Tate, HW Hillhouse and Y. Miyake, J. Mater . Chem . , 2007, 17, 3639 (e) C. Liang and S. Dai, J. Am . Chem . Soc ., 2006, 128, 5316.).

The nanopore array structure of the nanoporous carbon material synthesized by these various researchers has various structures of cube ( Ia3d , Im3m , Fm3m , Fd3m ) and cube ( p6mm ).

Catalytic sites in the nanoporous carbon material can be made by incorporation of transition metal compounds. In particular, nanoporous carbon materials containing magnetic materials such as Co, Ni, and Fe compounds are very useful because they can be easily separated using magnetic force after use as a heterogeneous catalyst or adsorbent in a solution. ((a) A.-H. Lu, W. Schmidt, N. Matoussevitch, H. B, B. Spliethoff, B. Tesche, E. Bill, W. Kiefer and F. Sch, Angew . Chem ., Int . Ed . , 2004, 43, 4303. (b) J. Lee, S. Jin, Y. Hwang, J.-G. Park, HM Park and T. Hyeon, Carbon , 2005, 43, 2536. (c) SM Holmes, PL Roberts and JM Newton, Chem . Commun . , 2005, 1912.)

Recently, several researchers have synthesized nanoporous carbon compounds containing magnetic transition metal compounds. Tartaj et al . is Fe ₃ O ₄ / γ-Fe ₂ O ₃ , CoFe ₂ O ₄ , LiCoPO ₄ , NiFe ₂ O ₄ , NiO, Cr ₂ O ₃ , and MnFe ₂ O ₄ Ball-shaped nanoporous carbon materials were prepared, including (a) AB Fuertes and P. Tartaj, Small, 2007, 3 (2), 275. (b) AB Fuertes, M. Sevilla, T. Valdand P . Tartaj, Chem. Mater., 2007, 19, 5418. (c) AB Fuertes, T. Vald, M. Sevilla and P. Tartaj, J. Phys. Chem. C 2008, 112, 3648.). And Ryoo et al. And Hyeon et al. Describe the pore arrangement of the hexagonal structure including Fe ₃ O ₄ / α-Fe, Co / CoO, Ni / NiO, Fe / Fe ₂ O ₃ , and Fe ₂ SiO ₄ . Eggplants synthesized nanoporous carbon materials ((a) J. Lee, S. Jin, Y. Hwang, J.-G. Park, HM Park and T. Hyeon, Carbon , 2005, 43, 2536. (b) I Park, M. Choi, T.-W. Kim and R. Ryoo, J. Mater . Chem . , 2006, 16, 3409.)

However, in order to synthesize nanoporous carbon materials containing such magnetic nanoparticles, they first synthesized nanoporous silica having nanopores or nanoporous materials having a hexagonal pore array structure, and then used the nanoporous silica materials as templates. The carbon source organic material and the transition metal compound source magnetic material were filled and carbonized in the nanopore. In addition, a nanoporous carbon material including magnetic particles was prepared by removing silica, which was used as a template, using a fluoric acid solution or a strong base solution. These carbon compounds contain nanoparticles of two or more complex compounds. In particular, iron compounds are present in the form of complex compounds such as Fe ₃ O ₄ / α-Fe ₂ O ₃ , Fe ₃ O ₄ / α-Fe, Fe / Fe ₂ O _3, and the like. In addition, the Fe ₂ SiO ₄ composite compound was formed as an additive material by nanoporous silica used as a template in the preparation of nanoporous carbon compounds containing magnetic iron oxide. In addition, in order to synthesize the nanoporous carbon compound including the magnetic nanoparticles, by using a fluoric acid or a strong base solution in the manufacturing process may cause serious environmental problems due to the waste liquid after use.

Ibuprofene is a nonsteroidal drug that is widely used to treat anti-stimulants, analgesics and arthritis. And because the biological half-life of this drug is two hours, continuous or controlled drug delivery is required. On the other hand, a therapeutically appropriate concentration of ibuprofen in the blood is 50 mg / L. If the concentration in the blood is more than 250 mg / L is rather toxic. Therefore, in such a situation, the necessity of removing with an adsorbent may be required. Therefore, many researchers have studied the adsorption of ibuprofen using a silica-based material having a large surface area and nanopores. The silica-based nanoporous material used here is Mcm-41, AlMcm-41, SBA-15, SBA-15 modified functional organic material, nanoporous silica porous ball, nanoporous nanoporous modified functional organic material Silica, SBA-3, SBA-1, Mcm-48 and LP-Ia3d ((a) G. Cavallaro, P. Pierro, FS Palumbo, F. Testa, L. Pasqua, R. Aiello and R. Aiello, Drug Deliv . 2004, 11, 41. (b) M. Vallet-Regi, A. Ramila, RP del Real and J. Perez-Pariente, Chem . Mater . , 2001, 13, 308. (c) Izquierdo-Barba, A. Martinez, AL Doadrio, J. Perez-Pariente and M. Vallet-Regi, Eur . J. Pharm . Sci. , 2005, 26, 365. (d) B. Munoz, A. Ramila, J. Perez-Pariente, I. Diaz and M. Vallet-Regi, Chem. Mater . (E) SW Song, K. Hidajat and S. Kawi, Langmuir , 2005, 21, 9568. (f) J. Andersson, J. Rosenholm, S. Areva and M. Linden, Chem . Mater . , 2004, 16, 4160. (g) YF Zhu, JL Shi, HR Chen, WH Shen and XP Dong, Turret Mat , 2005, 84, 218. (h) YF Zhu, JL Shi, WH Shen, HR Chen, XP Dong and ML Luan, Nanotechnology , 2005, 16, 2633.). The maximum adsorption of ibuprofen for these nanoporous materials has been reported to range from as low as 2.9 wt% to as high as 96.9 wt%. However, as described above, silica-based nanoporous materials have lower hydrolysis resistance to water and lower thermal and mechanical stability than carbon-based nanoporous materials. Carbon materials are also harmless enough to be used as oral abserbents to adsorb toxic or inorganic compounds (M. Melillo, VM Gun'ko, SR Tennison, LI Mikhalovska, GJ Phillips, JG Davies, AW Lloyd, OP Kozynchenko, DJ Malik, M, Streat and SV Mikhalosky, Langmuir , 2004, 20, 2837.). Melillo et al. Studied the adsorption of ibuprofen using activated carbon. The maximum adsorption amount of this material was 99.0 wt%. However, this activated carbon material does not have a regular array of pores and does not contain magnetic nanoparticles that allow easy separation using magnetic forces in solution.

It is an object of the present invention to provide nanoporous carbon materials having a large surface area, nanometer-sized pores and a regular pore arrangement, comprising a single kind of magnetic nanoparticles in the pores.

Another object of the present invention is to use a nano-porous carbon containing a magnetic nanoparticles prepared by using an organic material as a structure forming template, using an organic precursor as a material forming a pore wall, and using a transition metal compound as a precursor for preparing magnetic nanoparticles It is to provide a method for producing a material.

In addition, another object of the present invention is to prepare a nanoporous carbon material by using a mixed solution of a solution for preparing a nanoporous carbon material and a transition metal compound of various concentrations for the preparation of magnetic nanoparticles, and at the same time in a pore simultaneously with various contents of magnetic nanoparticles. It provides a method for producing a nanoporous carbon material comprising a.

In addition, another object of the present invention is to include a magnetic nanoparticles having various sizes in the pore at the same time to prepare a nanoporous carbon material by using a mixed solution of a solution for producing a nanoporous carbon material and a transition metal compound for the production of magnetic nanoparticles To provide a method for producing a nanoporous carbon material.

In addition, another object of the present invention is to prepare a nanoporous carbon material using a mixed solution of a solution for producing a nanoporous carbon material and a transition metal compound for the preparation of magnetic nanoparticles having various surface areas including magnetic nanoparticles in pores To provide a method for producing a nanoporous carbon material.

Another object of the present invention is to provide a nanoporous carbon material comprising magnetic nanoparticles separable by magnetic force in a solution using a mixed solution of a solution for preparing nanoporous carbon material and a transition metal compound for producing magnetic nanoparticles. It is to provide a manufacturing method.

In addition, another object of the present invention is to provide an environment-friendly manufacturing method that does not use acids or strong bases in the production of nanoporous carbon material containing magnetic nanoparticles.

In addition, another object of the present invention using a mixture solution of the transition metal compound for the preparation of nanoporous carbon material and the preparation of the magnetic nanoparticles, at the same time as the nanoporous carbon forming process to prepare the magnetic nanoparticles in the pores To simplify and to provide a manufacturing method that can reduce the waste liquid treatment cost by not using an acid or strong base to remove the silica.

It is another object of the present invention to provide a method for preparing nanoporous carbon material comprising magnetic nanoparticles as a high performance drug adsorbent.

It is another object of the present invention to provide a method for preparing a nanoporous carbon material comprising magnetic nanoparticles separable by magnetic force in a solution and adsorbing a drug.

The above technical problem is to use a terpolymer copolymer as a template, an organic precursor as a material constituting a pore wall, and a nanoparticle precursor having magnetic properties, using a compound in the transition metal, This can be achieved by synthesizing a nanoporous carbon material comprising nanoparticles with a regular pore arrangement and magnetizing in the pores in a single reaction vessel and using this material for adsorption of ibuprofen drug.

Preferably, the nanoporous carbon material including the nanoparticles having magnetic properties in the pores may be prepared by using an organic-organic self-assembly method using the organic material as a material forming the structure forming template and the pore wall of the organic material.

Preferably, the nano-containing nanoparticles stand magnetism in the pore pore carbon material {poly (ethylene oxide), poly terpolymer as structure-forming template (propylene oxide) - poly (ethylene oxide), poly (ethylene oxide) block -poly (propylene oxide) - block - poly (ethylene oxide)) or poly (propylene oxide) poly (ethylene oxide) -poly (propylene oxide) poly (propylene oxide) - block - poly (ethylene oxide) - block -poly ( propylene oxide)}, or two won copolymer {poly (ethylene oxide), poly (styrene), poly (ethylene oxide) - block -poly (styrene), poly (4-vinylpyridine), poly (styrene), poly (4- vinylpyridine) polystyrene} may be selected.

Preferably, the carbonaceous material comprising nanoparticles that are magnetic in the pores is phenol-formaldehide, resocinol-formaldehide or phloglogue as the leading organic source of the carbon pore wall. It may be one selected from the group of phloroglucinol-formaldehide.

Preferably, phenol-formaldehide, the leading organic material of the carbon pore wall, is prepared using precursors of phenol and formaldehyde and has a molecular weight of about 500 g / mol.

Preferably, the carbon material comprising the nanoparticles magnetic in the pores is prepared in one reaction vessel using a mixture of a solution for synthesizing the nanoporous carbon material and a transition metal compound solution for producing the magnetic nanoparticles. It may be.

Preferably, the nanoporous carbon material including the nanoparticles having magnetic properties in the pores may have a pore array having a hexagonal structure, a cube structure, or a disordered structure.

Preferably, the nanoporous carbon material including nanoparticles exhibiting magnetism in the pores may have various pore sizes.

Preferably, the various pore sizes may be selected from 23.2 mm 3, 26.3 mm 3, and 36.0 mm 3, respectively.

Preferably, the nanoporous carbon material comprising nanoparticles magnetic in the pores may be of various surface areas.

Preferably, the various surface areas may be selected from 339.2 m 2 / g, 635.4 m 2 / g, and 605.5 m 2 / g.

Preferably, the nanoporous carbon material including the nanoparticles exhibiting magnetism in the pores may be one having magnetic nanoparticles of various sizes.

Preferably, the magnetic nanoparticles of various sizes may be selected from those having a size between at least 4.2 nm and at most 20.9 nm.

Preferably, the nanoporous carbon material including the nanoparticles having magnetic properties in the pores may have magnetic nanoparticles of various contents.

Preferably, the magnetic nanoparticles of various contents may be selected from a metal atom content of at least 0.5wt% to at most 2.5wt%.

Preferably, the magnetic nanoparticles included in the pores of the nanoporous carbon material may be prepared using various transition metal compounds.

Preferably, the various transition metal compounds are Fe (CH ₃ COO) ₂ , Fe (NO ₃ ) ₃ , FeCl ₂ , FeCl ₃ , FeBr ₂ , FeBr ₃ , Ni (CH ₃ COO) ₂ , Fe (NO ₃ ) ₂ , It may be selected from NiCl ₂ , NiBr ₂ , NiI ₂ , Co (CH ₃ COO) ₂ , Co (NO ₃ ) ₂ , CoCl ₂ , CoSO ₄ .

Preferably, the high-performance drug adsorbent may be a nanoporous carbon material including magnetic nanoparticles.

Preferably, it may be to use a nanoporous carbon material comprising magnetic nanoparticles for high performance drug adsorbent and separable by magnetic force in solution.

In addition, the technical problem of the present invention is that the nanoporous carbon material having magnetic nanoparticles in the nanopore by using the synthesis method in the reaction vessel prepared above, and the high-performance drug adsorption capacity using the material is X-ray scattering, X-ray diffraction, nitrogen isothermal adsorption / It may be achieved through desorption, transmission electron microscopy, X-ray photoelectron spectroscopy, susceptibility, ultraviolet / visible spectroscopy, and photography.

As described in detail above, the present invention uses a terpolymer copolymer as a template, an organic precursor as a material forming a pore wall, and a large surface area (635.4 m 2 / g), a synthesis method using organic-organic self-assembly in a reaction vessel made of carbon material containing nanometer-sized pores and nanoparticles having a regular pore arrangement and magnetic particles in pores. This material was used to demonstrate a good capacity (995 mg / g) for adsorption of ibuprofen drug.

In addition, the manufacture of nanoporous carbon containing magnetic nanoparticles does not include the removal of silica molds, so the waste solution of acids or strong bases is not discharged, thus reducing the cost of manufacturing nanoporous carbon materials containing magnetic nanoparticles by an eco-friendly and simple manufacturing process. You can also expect the effect.

In the present invention, a terpolymer is used as a template, an organic precursor is used as a material for forming a pore wall, and a transition surface metal compound is used as a nanoparticle precursor with magnetic properties. Nanoporous carbon materials containing a single type of magnetic nanoparticles in pores were synthesized. Thus, it is more resistant to water than silica material and contains magnetic nanoparticles so that they can be easily separated by magnetic force in solution. The nanoporous carbon material containing the magnetic nanoparticles showed higher adsorption capacity (99.5 wt%) for the ibuprofen drug than the nanoporous silica material. In addition, when synthesizing the nanoporous carbon material including the magnetic nanoparticles, a reaction solution for synthesizing the nanoporous carbon material and a metal compound for forming the magnetic nanoparticles are mixed, and then a nanoporous carbon material is prepared by a carbonization process. In the process, nanoporous carbon material is formed and at the same time, a kind of magnetic nanoparticle is formed in the nanopore. Therefore, it is easier and more efficient because it synthesizes nanoporous silica material, uses this material as a template, fills the organic material in the pores, and undergoes a much simpler manufacturing process than carbonizing nanoporous carbon including magnetic nanoparticles through carbonization. In addition, when synthesizing nanoporous carbon containing magnetic nanoparticles using nanoporous silica material as a template, it is essential to use fluoric acid or strong base solution to remove silica that was used as a template in the last step. One waste liquid is discharged. However, since the present invention does not go through such a process, it can be said to be a method for producing nanoporous carbon materials including much more environmentally friendly magnetic nanoparticles.

An example of a manufacturing process through an organic-organic self-assembly method of nanoporous carbon material having a very high surface area, regular pores of nanometer size and including magnetic nanoparticles is schematically illustrated in FIG. Although the case where the phenol-aldehyde organic oligomer is used as a carbon source which is a wall material is shown, it is a thing of course not limited to this.

As shown in FIG. 1, nanoporous carbon materials comprising magnetic nanoparticles are organic (eg, phenol-aldehydes) as carbon porewall formation precursors, block copolymers as templates, and transferred to magnetic inorganic sources. Nanoporous carbon materials are formed by a self-assembly process and a carbonization process with a mixed solution containing a metal compound.

Phenol-formaldehide, risocinol-formaldehide or phloroglucinol-formaldehide may be used as a leading organic material source of the carbon pore wall. Preferably phenol-formaldehide can be applied, the molecular weight of which is preferably about 500 m 2 / g.

In addition, an example of the block copolymer that may be used as a template ternary copolymer {poly (ethylene oxide) poly (propylene oxide) poly (ethylene oxide), poly (ethylene oxide) - block -poly (propylene oxide) - block -poly ( ethylene oxide), hereinafter PEO-PPO-PEO terpolymer) or poly (propylene oxide) poly (ethylene oxide) -poly (propylene oxide) poly (propylene oxide) - block -poly (ethylene oxide) - block -poly (propylene oxide), hereinafter PPO-PEO-PPO terpolymer} or, binary copolymer {poly (ethylene oxide), poly (styrene), poly (ethylene oxide) - block -poly (styrene), less than two won PS-PEO copolymer , Poly (4-vinylpyridine) poly (styrene), poly (4-vinylpyridine) polystyrene, hereinafter P4VP-PS binary copolymer} and the like, and preferably, poly (ethylene oxide) poly (propylene oxide) poly (ethylene oxide) ), poly (ethylene oxide) - block -poly (propylene oxide) - block -poly (ethyl ene oxide).

And the magnetic nanoparticle inorganic source is Fe (CH ₃ COO) ₂ , Fe (NO ₃ ) ₃ , FeCl ₂ , FeCl ₃ , FeBr ₂ , FeBr ₃ , Ni (CH ₃ COO) ₂ , Fe (NO ₃ ) ₂ , NiCl ₂ , NiBr ₂ , NiI ₂ , Co (CH ₃ COO) ₂ , Co (NO ₃ ) ₂ , CoCl ₂ , CoSO _4, and the like, and preferably Fe (NO ₃ ) ₂ may be applied.

As such, the formation of nanoporous carbon materials containing magnetic nanoparticles having a regular and constant pore size and high surface area (about 600 m 2 / g or more) may be performed by mixing a magnetic inorganic source with a reaction solution for forming nanoporous carbon. It is carried out by self-assembly of the organic template material and the pore wall forming organic material through the vaporization process, and the polymerization reaction at 100 ℃.

Carbonization of the nanostructured template / polymer / metal ion composite material obtained through such a heating reaction at a temperature of 600 ° C. or higher under nitrogen or argon gas results in a nanoporous carbon material containing regular pore arrangement, high surface area, and magnetic nanoparticles. Are manufactured.

The surface area of the nanoporous carbon material including the magnetic nanoparticles has a value of 635.4 m 2 / g to 339.2 m 2 / g and the size of the regularly arranged pores is 36.0 mm 2 to 23.3 mm 3. Preferred surface areas and pore sizes are 635 m 2 / g and 36.0 mm 3, respectively.

The size of the nano magnetic particles in the nanoporous carbon material has a value of 4.2 nm to 20.9 nm and the preferred size of the nano magnetic particles is 10.2 nm.

The nanoporous carbon material including the magnetic nanoparticles formed as described above may have pore arrangements of various cubes ( Im3m , Fd3m , Ia3a ) and hexagonal ( p6mm ) structures, as shown in FIG. 2.

The excellent adsorption capacity and usefulness of the nanoporous carbon material including the magnetic nanoparticles to the drug is achieved through a stirring method on a solution using an ibuprofene drug, as schematically shown in FIG. 3.

At this time, the solution for dissolving ibuprofen may be alcohol, hexane, DMSO, DMF, or DMA, and preferably hexane can be applied.

The structure and properties of the nanoporous carbon material having magnetic nanoparticles in the nanopore using the synthesis method in a single reaction vessel prepared above, and the high-performance drug adsorption capacity using the material are X-ray scattering, X-ray diffraction, nitrogen isothermal adsorption / desorption , Transmission electron microscopy, X-ray photoelectron spectroscopy, susceptibility, ultraviolet / visible spectroscopy, and photography.

Hereinafter, the present invention will be described in detail with reference to Examples, but the present invention is not limited to these Examples.

Example 1

Phenol-aldehyde Oligomer  Preparation of Organic Source

Figure 4 is a flow chart showing the manufacturing process of the phenol-aldehyde oligomer which is the leading material of the carbon constituting the pore wall of the nanoporous carbon material according to an embodiment of the present invention.

Referring to the manufacturing process of the phenol-aldehyde oligomers, first, 0.61 g of phenol and 1.05 g of 37% formaldehyde solution are mixed with 0.13 g of 20 wt% sodium hydroxide (step S41). And it heats for 1 hour at 70-75 degreeC, stirring (step S42). Then, after cooling to room temperature (step S43), the solution is neutralized to pH = 7 with 0.6 M hydrochloric acid solution (step S44). Water is then removed under vacuum (step S45), and the resulting phenol-aldehyde oligomer material is prepared to 20wt% in ethanol solution (step S46).

Preparation of Nanoporous Carbon Materials with Magnetic Nanoparticles Using a Single Reaction Vessel and Organic-Organic Self-Assembly Method

5 is a flowchart illustrating a process of preparing a nanoporous carbon material including magnetic nanoparticles according to an exemplary embodiment of the present invention.

First, 1 g of terpolymer (PEO ₁₀₆ PPO ₇₀ PEO ₁₀₆ ) is dissolved in 20 g of ethanol (step S51). Then, three solutions containing 0.1447 g, 0.0724 g, and 0.3618 g of Fe (NO ₃ ) ₃ , respectively, were prepared in this solution (step S52). To each of these three solutions is added 5 g of a 20 wt% phenol-aldehyde oligomer (molecular weight of about 500 g / mol) ethanol solution (step S53). The reaction solution is dispersed in an organic container (step S54). Then, the mixture is sufficiently dried at room temperature and then heated at 100 ° C. for 24 hours to polymerize (step S55). The sample is collected and carbonized at 600 ° C., 700 ° C., and 900 ° C. under nitrogen or argon to obtain a nanoporous carbon material including magnetic nanoparticles (step S56).

Adsorption of Ibuprofen Using Nanoporous Carbon Materials with Magnetic Nanoparticles

6 is a flow chart showing the adsorption process of ibuprofen drug using a nanoporous carbon material including magnetic nanoparticles according to an embodiment of the present invention.

Firstly, seven different concentrations of the O ibuprofen hexane solution ^{4.7 × 10 -3 M, 9.4 ×} 10 -3 M, 1.89 × 10 -2 M, 3.75 × 10 -2 M, 7.5 × 10 -2 M, 1.0 × 10 - ¹ M and 1.5 x 10 ^-1 M are prepared in 5 ml portions (step S61). A nanoporous carbon material containing 0.02 g of magnetic nanoparticles is then added to the ibuprofen hexane solution, each having seven different concentrations (step S62). After stirring for 12 hours at room temperature, it is filtered (step S63). The solution is determined by using ultraviolet / visible spectroscopy to determine the amount of ibuprofen adsorbed and the solid material is dried at 40 ° C. for 12 hours (step S64).

Identification and evaluation of the product

The nanopore array structure of the nanoporous carbon material including the magnetic nanoparticles was confirmed using a low angle X-ray scattering pattern. As shown in FIG. 7, in the low angle X-ray scattering pattern of the nanoporous carbon material (0.5 wt% Fe-FDU-15) containing 0.5 wt% Fe, the sample before carbonization has a relatively low peak intensity. This is because the distinction between the pore walls and the pores is not clear because there is a terpolymer (PEO ₁₀₆ PPO ₇₀ PEO ₁₀₆ ) used as the template material in the pores in the nano structured mold / polymer composite. This is because the density of the polymer (phenol-aldehyde polymer) constituting the pore wall is low. However, they show peaks (100), (110), (200), and (210), which are typical X-ray scattering patterns showing very regular pore arrays ( p6mm ). The d -spacing value of this material was 139.9 mm 3. After carbonizing the nano structured template / polymer composite at 600 ° C., the intensity of the peaks increased significantly. And the X-ray scattering pattern shows a typical and very regular cubic array of p6mm . The d -spacing value of this material was 99.7 mm 3, which was reduced by 40.2 mm 3 compared to before carbonization. This result is caused by shrinkage of the nanopore walls as they are carbonized at high temperatures. As the carbonization temperature increased to 900 ° C, the intensity of the peak decreased slightly. This is because the pore structure slightly collapses at high temperatures. X-ray scattering patterns, however, show that nanoporous carbon materials, including magnetic nanoparticles, still maintain the pore arrangement of a typical, highly regular hexagonal structure ( p6mm ). The d -spacing value of this material is 95.2 kPa. As carbonized at a high temperature of 900 ° C., the d -spacing value further decreased.

In the low angle X-ray scattering pattern of nanoporous carbon material (1wt% Fe-FDU-15) containing 1wt% Fe, the X-ray scattering pattern before and after carbonization is also typical and very regular hexagonal structure ( p6mm ) pores Show an array However, after carbonization at a high temperature of 900 ° C., the nanoporous structure collapsed. D of the carbonized sample at 600 ℃ and 700 ℃ - distance value d larger than 0.5wt% Fe-FDU-15 sample carbonized by 103.0Å - has a distance value.

In the low angle X-ray scattering pattern of the nanoporous carbon material (1 wt% Fe-FDU-15) containing 2.5 wt% Fe, an X-ray scattering pattern showing the pore arrangement of the hexagonal structure for the sample before carbonization is shown. As the Fe content increases to 2.5 wt%, the X-ray scattering pattern shows two peaks of (100) and (110). This shows that the pore ordering is lower than that of 0.5 wt% Fe-FDU-15 and 1 wt% Fe-FDU-15 samples. The d -spacing value of this material was 134.2 mm 3. After carbonization at 600 ° C. and 700 ° C., the intensity of the peak increases and shows a regular hexagonal pore arrangement. The d -spacing value of these materials was 95.2 Å. However, the sample after carbonization at a high temperature of 900 ° C. collapsed the nanoporous structure.

The analysis of low angle X-ray scattering patterns for three samples, 0.5wt% Fe-FDU-15, 1wt% Fe-FDU-15, 2.5wt% Fe-FDU-15, showed that 1wt% Fe-FDU-15 For samples carbonized at 600 ° C and 700 ° C, they have the highest d -spacing value (103.0 Å) and the highest peak intensity, indicating the highest degree of nanopore array.

FIG. 8 shows X-ray diffraction patterns at elevations before and after carbonization for 0.5 wt% Fe-FDU-15, 1 wt% Fe-FDU-15, and 2.5 wt% Fe-FDU-15 samples. Before carbonization, all three samples do not show characteristic peaks. Characterized peaks indicated by red dots appear after carbonization of a sample containing 0.5 wt% Fe (0.5 wt% Fe-FDU-15) at 600 ° C. These peaks indicate the formation of magnetite (Fe ₃ O ₄ ), a magnetic iron oxide. At this time, the size of the magnetite was 4.2nm as shown in FIG. As the carbonization temperature is increased to 900 ℃ intensity of the peak to mean the formation of a magnetite (Fe ₃ O ₄₎ it is increased and magnetite (Fe ₃ O ₄₎ The size of the particles was increased by 14.9 ㎚.

Characteristic peaks indicating the formation of magnetite (Fe ₃ O ₄ ) particles appeared after carbonization of a sample containing 0.5 wt% Fe (0.5 wt% Fe-FDU-15) at 600 ° C. The size of this nanoparticle was 6.1 nm. After carbonization at 700 ° C., the size of the magnetite (Fe ₃ O ₄ ) particles was 10.2 nm. After carbonization at 900 ° C, various kinds of iron compounds such as magnetite, maghemite, iron carbide, and iron oxide (FeO) were formed in the nanoporous carbon. Among these, the size of the magnetite (Fe ₃ O ₄ ) particles was 27.8 nm.

As the Fe content (2.5 wt% Fe-FDU-15) increased to 2.5 wt%, the size of the magnetite (Fe ₃ O ₄ ) particles after carbonization at 600 ° C., 700 ° C., and 900 ° C. was 12.5 nm, 18.6 nm. , 20.9 nm. After carbonization, all samples produced magnetite (Fe ₃ O ₄ ) and iron carbide.

Therefore, as a result of analyzing the elevation X-ray diffraction pattern, as the carbonization temperature increases, the size of the magnetite (Fe ₃ O ₄ ) particles increases and other iron compounds (maghemite, iron carbide, and iron oxide (FeO)) are simultaneously formed. . As the Fe content was increased, the size of the magnetite (Fe ₃ O ₄ ) particles increased and other iron compounds were simultaneously formed.

FIG. 10 shows 0.5 wt% (0.5 wt% Fe-FDU-15 (700)) and 1 wt% (1 wt% Fe-FDU-15) of Fe-free nanoporous carbon (FDU-15 (700)) and Fe, respectively. (700)), a nitrogen adsorption / desorption isotherm curve for nanoporous carbon carbonized at 700 ° C of a sample containing 2.5 wt% (2.5 wt% Fe-FDU-15 (700)). All samples show the nitrogen adsorption / desorption isotherm shape as they show nanopores. And, Figure 11 shows the nanopore size distribution. All samples show very narrow pore distribution. This indicates that all samples have nanopores of very uniform size. In addition, as shown in Figure 12, except that 0.5wt% Fe-FDU-15 (700) sample shows that the pore size decreases from 36.0 Å to 26.3 따라 as the Fe content increases. In the case of the 1 wt% Fe-FDU-15 (700) sample, it has a pore size similar to that of the sample containing no Fe (FDU-15 (700)). In addition, as the Fe content was increased to 2.5wt%, the BET surface area decreased from 635.4㎡ / g to 339.2㎡ / g. The 1 wt% Fe-FDU-15 (700) sample had the highest BET surface area (635.4 m 2 / g).

In conclusion, the nanoporous carbon material (1wt% Fe-FDU-15 (700) containing 1wt% Fe and carbonized at 700 ° C from the results of X-ray scattering pattern, X-ray diffraction pattern, nitrogen adsorption / desorption isotherm and pore distribution ) Has the largest surface area and pore size, and has pure magnetite (Fe ₃ O ₄ ) nanoparticles of 10.2 nm size with highly regular hexagonal pore arrays.

FIG. 13 is a transmission electron micrograph of a nanoporous carbon material (1 wt% Fe-FDU-15 (700)) containing 1 wt% Fe and carbonized at 700 ° C. FIG. Figure 13 (a) is a transmission electron micrograph, viewed perpendicular to the nanopore array direction, Figure 13 (b) is a transmission electron micrograph, viewed parallel to the nanopore array direction. And the black dots are magnetic nanoparticles. From these transmission electron micrographs, it can be seen that the nanoporous carbon material including the magnetic substance has a very regular hexagonal pore array structure and the magnetite (Fe ₃ O ₄ ) magnetic nanoparticles are very well dispersed.

FIG. 14 is an X-ray photoelectron spectrum of a nanoporous carbon material (1 wt% Fe-FDU-15 (700)) containing 1 wt% Fe and carbonized at 700 ° C. FIG. The two peaks at 711.4 eV and 724.8 eV are due to Fe in the magnetite (Fe ₃ O ₄ ) material. This proves that the iron oxide in 1 wt% Fe-FDU-15 (700) is pure magnetite (Fe ₃ O ₄ ). This result is consistent with the results showing only the magnetite (Fe ₃ O ₄ ) peak in the high-angle X-ray diffraction pattern of FIG. 8.

FIG. 15 shows the magnetization of a nanoporous carbon material (1 wt% Fe-FDU-15 (700)) containing 1 wt% Fe and carbonized at 700 ° C. FIG. The saturation magnetization (M _s ) value is 7.7. The ratio of residual magnetism to saturated magnetism is 0.04, which is very low. This indicates that the magnetic material (magnetite (Fe ₃ O ₄ )) contained in the nanoporous carbon has ferromagnetic properties.

FIG. 16 shows the amount of ibuprofen adsorbed to the adsorbent versus the amount of ibuprofen added using nanoporous carbon material (1wt% Fe-FDU-15 (700)) containing 1 wt% Fe and carbonized at 700 ° C. This graph shows the amount. The amount of added ibuprofen was added from 1.12 × 10 ⁻³ mol to 3.75 mol for 1 g of adsorbent. As the amount of added ibuprofen increased, the amount of ibuprofen relative to the adsorbent increased. Since the amount of added ibuprofen was 1.12 × 10 ⁻³ mol or more, the amount of ibuprofen adsorbed on the adsorbent was almost constant. The maximum amount of ibuprofen adsorbed on 1 g of the adsorbent was 995 mg. The inset shows that a 1wt% Fe-FDU-15 (700) material containing magnetite (Fe ₃ O ₄ ) magnetic material adsorbed with ibuprofen can be separated by dragging with a magnet in the ibuprofen solution. Shows.

FIG. 17 shows a low angle X-ray scattering pattern of pure 1 wt% Fe-FDU-15 (700) and 1 wt% Fe-FDU-15 (700) adsorbed with various amounts of ibuprofen. The intensity of the peak decreases as the amount of ibuprofen adsorbed using 7.5 × 10 ⁻² M of ibuprofen solution increases to 4.8 × 10 ⁻³ mol / g. This is a result of the distinction between the pore wall and the pores as the ibuprofen is adsorbed in the nanopore. And 1.0 × 10 ^-1 to M and 1.5 × 10 ^-1 M ah amount of adsorbed O ibuprofen using the ibuprofen solution, 4.9 × 10 ^-3 mol / g and ^{5.0 × 10 -3 mol / g,} 7.5 × 10 - ^It is almost similar to the amount of ibuprofen (4.8 × 10 ⁻³ mol / g) adsorbed using ² M of ibuprofen solution. This indicates that the adsorbent was saturated with at least 7.5 × 10 ⁻² M of ibuprofen solution. Therefore, the peak intensity of the X-ray scattering pattern is similar.

These results can also be confirmed by nitrogen adsorption / desorption isotherm and pore size distribution. FIG. 18 shows nitrogen adsorption / desorption isotherms of pure 1 wt% Fe-FDU-15 (700) and 1 wt% Fe-FDU-15 (700) adsorbed with various amounts of ibuprofen. As the amount of ibuprofen adsorbed on 1 wt% Fe-FDU-15 (700) increases, the adsorption amount of nitrogen decreases. As shown in FIG. 20, the BET surface area of the adsorbent 1wt% Fe-FDU-15 (700) increased from 635.4 m 2 / g to 185.4 m 2 / g as the amount of adsorbed ibuprofen increased to 4.8 × 10 ⁻³ mol / g. Decreased. In addition, the BET surface area was 180.7 m 2 / g for the sample after the ibuprofen saturation, the change in surface area is insignificant.

19 shows the pore size distribution of pure 1wt% Fe-FDU-15 (700) and 1wt% Fe-FDU-15 (700) adsorbed with various amounts of ibuprofen. As the amount of adsorbed ibuprofen increases, the narrow pore distribution at 36.0 Å decreases gradually and shows a broad pore distribution. Then, the decreased study years as the amount of adsorbed O ibuprofen increase in blood 0.48㎝ ^-3 0.19㎝ to ^-3, as shown in Fig. For samples after saturation of ibuprofen, the pore volume was about 0.20 cm ^{-3, which} is almost similar.

In conclusion, the ibuprofen drug was clearly adsorbed in the pores of the adsorbent using low angle X-ray scattering pattern, nitrogen adsorption / desorption isotherm and pore distribution. In addition, nanoporous carbon materials containing magnetic magnetite (Fe ₃ O ₄ ) have been found to be excellent adsorbents for ibuprofen drugs. The maximum adsorption amount of the ibuprofen drug of the 1 wt% Fe-FDU-15 (700) adsorbent was 995 mg per 1 g of the adsorbent.

Although the above has been described with reference to the preferred embodiment of the present invention, various changes and modifications can be made without departing from the technical spirit of the present invention. Therefore, the scope of the present invention should not be limited to the above embodiments, but should be determined by the claims described below.

1 is a schematic diagram of a process for producing an organic-organic self-assembly of a nanoporous carbon material having a very high surface area, regular pores of nanometer size, and including magnetic nanoparticles.

2 is a representative pore array structure of a nanoporous carbon material including magnetic nanoparticles.

Figure 3 is a schematic diagram of the adsorption process for the ibuprofen drug using a nanoporous carbon material containing magnetic nanoparticles.

Figure 4 is a flow chart showing the manufacturing process of the phenol-aldehyde oligomer which is the leading material of the carbon constituting the pore wall of the nanoporous carbon material according to an embodiment of the present invention.

5 is a flowchart illustrating a process of preparing a nanoporous carbon material including magnetic nanoparticles according to an exemplary embodiment of the present invention.

6 is a flow chart showing the adsorption process of ibuprofen drug using a nanoporous carbon material including magnetic nanoparticles according to an embodiment of the present invention.

7 is a low angle X-ray scattering pattern of the nanoporous carbon material including the magnetic nanoparticles of the present invention.

8 is an elevation X-ray diffraction pattern of a nanoporous carbon material including the magnetic nanoparticles of the present invention.

FIG. 9 is a table summarizing sizes of magnetite nanoparticles according to carbonization temperatures of nanoporous carbon materials having various Fe contents.

10 is a nanoporous carbon (FDU-15 (700)) does not include the present invention and nanoporous carbon (0.5wt% Fe-FDU-15 (700)) having various Fe contents, 1wt% (1wt% Fe -FDU-15 (700)), 2.5wt% (2.5wt% Fe-FDU-15 (700)) is carbon adsorption / desorption isothermal curve after carbonization at 700 ° C.

11 is a nanoporous carbon (FDU-15 (700)) does not contain Fe and the nanoporous carbon 0.5wt% (0.5wt% Fe-FDU-15 (700)) having a variety of Fe content, 1wt% ( 1wt% Fe-FDU-15 (700)) and 2.5wt% (2.5wt% Fe-FDU-15 (700)) are pore distributions after carbonization at 700 ° C.

12 is a nanoporous carbon (FDU-15 (700)) does not include the present invention and 0.5wt% (0.5wt% Fe-FDU-15 (700)) having various Fe contents, 1wt% ( 1wt% Fe-FDU-15 (700)) and 2.5wt% (2.5wt% Fe-FDU-15 (700)) is a table that summarizes the surface area, pore volume, and pore size of the sample carbonized at 700 ° C.

FIG. 13 is a transmission electron micrograph of a nanoporous carbon material (1 wt% Fe-FDU-15 (700)) containing 1 wt% Fe of the present invention and carbonized at 700 ° C. FIG.

FIG. 14 is an X-ray photoelectron spectrum of a nanoporous carbon material (1 wt% Fe-FDU-15 (700)) containing 1 wt% Fe of the present invention and carbonized at 700 ° C. FIG.

FIG. 15 shows the magnetization rate of a nanoporous carbon material (1 wt% Fe-FDU-15 (700)) containing 1 wt% Fe of the present invention and carbonized at 700 ° C. FIG.

FIG. 16 shows the adsorbed amount of ibuprofen versus the amount of ibuprofen added using nanoporous carbon material (1 wt% Fe-FDU-15 (700)) containing 1 wt% Fe and carbonized at 700 ° C. as an adsorbent. This graph shows the amount of ibuprofen.

17 is a low angle X-ray scattering pattern of pure 1wt% Fe-FDU-15 (700) and 1wt% Fe-FDU-15 (700) adsorbed with various amounts of ibuprofen according to the present invention.

18 is a nitrogen adsorption / desorption isotherm of pure 1wt% Fe-FDU-15 (700) and 1wt% Fe-FDU-15 (700) adsorbed with various amounts of ibuprofen.

19 is a pore size distribution diagram of 1 wt% Fe-FDU-15 (700) of the present invention and 1 wt% Fe-FDU-15 (700) adsorbed with various amounts of ibuprofen.

20 is a table summarizing the surface area and pore volume of the present invention pure 1wt% Fe-FDU-15 (700) and 1wt% Fe-FDU-15 (700) adsorbed with various amounts of ibuprofen.

Claims (33)

A nanoporous carbon material comprising magnetic nanoparticles prepared using an organic-organic self-assembly method using an organic material as a material forming a structure forming mold and a pore wall of an organic material. The method according to claim 1, As the structure forming template, terpolymer (poly (ethylene oxide) poly (propylene oxide) -poly (ethylene oxide), poly (ethylene oxide) -block -poly (propylene oxide) -block -poly (ethylene oxide)) or poly (propylene oxide) poly (ethylene oxide) -poly (propylene oxide) poly (propylene oxide) - block -poly (ethylene oxide) - block -poly (propylene oxide)} or, binary copolymer {poly (ethylene oxide), poly (Styrene), poly (ethylene oxide) -block -poly (styrene), poly (4-vinylpyridine) poly (styrene), poly (4-vinylpyridine) poly-styrene} Nanoporous carbon material comprising nanoparticles. The method according to claim 1, It is selected from phenol-formaldehide, resocinol-formaldehide or phloroglucinol-formaldehide as a precursor organic material source of the carbon pore wall of the nanoporous carbon. Nanoporous carbon material comprising magnetic nanoparticles characterized in that. The method according to claim 3, The molecular weight of the phenol-formaldehyde (phenol-formaldehide) is a nanoporous carbon material comprising a nanoparticle having a magnetic properties, characterized in that 500g / mol. The method according to claim 1, Nanoporous carbon comprising magnetic nanoparticles, characterized in that for preparing in a single reaction vessel using a mixture of a solution for synthesizing the nanoporous carbon material and a transition metal compound solution for producing magnetic nanoparticles matter. The method according to claim 5, The carbon material is a nanoporous carbon material comprising nanoparticles having magnetic properties, characterized in that the pore arrangement is selected from a cube structure, a cube structure, and a disordered structure. The method according to claim 1, The carbon material is a nanoporous carbon material comprising a nanoparticle having a magnetic feature, characterized in that it has a plurality of pore sizes. The method of claim 7, The pore size is nanoporous carbon material comprising magnetic nanoparticles, characterized in that selected from 23.2 Å, 26.3 Å, and 36.0 Å. The method according to claim 1, The carbon material is a nanoporous carbon material comprising a nanoparticle having a magnetic feature, characterized in that having a plurality of surface areas. The method according to claim 9, Wherein said surface area is selected from 339.2 m 2 / g, 605.5 m 2 / g, and 635.4 m 2 / g. The method according to claim 1, The carbon material is a nanoporous carbon material comprising a nanoparticle having a magnetic feature, characterized in that having a plurality of magnetic nanoparticles. The method of claim 11, The nanoporous carbon material comprising magnetic nanoparticles, characterized in that the size is between a minimum of 4.2nm and a maximum of 20.9nm. The method according to claim 1, The carbon material is a nano-porous carbon material comprising nanoparticles having magnetic properties, characterized in that it has a plurality of magnetic nanoparticles. 14. The method of claim 13, The content is nanoporous carbon material comprising a magnetic nanoparticles characterized in that the content of the metal atom of at least 0.5wt% to 2.5wt%. The method according to claim 11 or 13, A nanoporous carbon material comprising nanoparticles having magnetic properties, characterized in that a plurality of transition metal compounds are used as precursors of the magnetic nanoparticles. The method according to claim 15, The transition metal compound may be Fe (CH ₃ COO) ₂ , Fe (NO ₃ ) ₃ , FeCl ₂ , FeCl ₃ , FeBr ₂ , FeBr ₃ , Ni (CH ₃ COO) ₂ , Fe (NO ₃ ) ₂ , NiCl ₂ , Nanoporous carbon material comprising magnetic nanoparticles, characterized in that selected from NiBr ₂ , NiI ₂ , Co (CH ₃ COO) ₂ , Co (NO ₃ ) ₂ , CoCl ₂ , CoSO ₄ . The method according to any one of claims 1 to 14, A nanoporous carbon material comprising magnetic nanoparticles, wherein the carbon material is used as a high performance ibuprofen drug adsorbent. The method according to claim 17, Nanoporous carbon material comprising magnetic nanoparticles for the high-performance ibuprofen drug adsorbent, characterized in that the magnetic particles are characterized in that the magnetic force in the solution can be separated. Fabrication of nanoporous carbon materials comprising nanostructured carbon material comprising magnetic nanoparticles using organic-organic self-assembly using organic materials Way. The method of claim 19, Method for producing a nano-porous carbon material, characterized in that it is prepared in a single reaction vessel using a mixture of a solution for synthesizing the nano-porous carbon material and a transition metal compound solution for the production of magnetic nanoparticles. The method of claim 19, A method for producing a nanoporous carbon material comprising nanoparticles using the organic-organic self-assembly method and having magnetic properties by synthesis in a single reaction vessel, wherein the nanopores have different pore sizes. 23. The method of claim 21, Wherein the pore size is selected from 23.2 mm 3, 26.3 mm 3, and 36.0 mm 3. The method of claim 19, A method for producing a nanoporous carbon material comprising nanoparticles using the organic-organic self-assembly method and having magnetic properties by synthesis in a single reaction vessel, wherein the nanopores have different surface areas. The method according to claim 23, The surface area is selected from 339.2 m 2 / g, 605.5 m 2 / g, and 635.4 m 2 / g. The method of claim 19, Method of producing a nano-porous carbon material using the organic-organic self-assembly method and having magnetic nanoparticles of different sizes by synthesis in a single reaction vessel. The method according to claim 25, The magnetic nanoparticles are selected from the one having a size between a minimum of 4.2nm and a maximum of 20.9nm. The method according to claim 19 or 25, Method for producing a nano-porous carbon material using the organic-organic self-assembly method and having a magnetic nanoparticles of different contents by synthesis in a single reaction vessel. The method of claim 27, The magnetic nanoparticles are a method of producing a nanoporous carbon material, characterized in that selected from a minimum of 0.5wt% to 2.5wt% of the metal atom content. The method of claim 19, The organic-organic self-assembly method and the synthesis method in a single reaction vessel using a transition metal compound as a precursor of the nanoparticles exhibiting magnetic properties. The method of claim 29, The transition metal compound may be Fe (CH ₃ COO) ₂ , Fe (NO ₃ ) ₃ , FeCl ₂ , FeCl ₃ , FeBr ₂ , FeBr ₃ , Ni (CH ₃ COO) ₂ , Fe (NO ₃ ) ₂ , NiCl ₂ , NiBr ₂ , NiI ₂ , Co (CH ₃ COO) ₂ , Co (NO ₃ ) ₂ , CoCl ₂ , CoSO _{4 A} method for producing a nanoporous carbon material, characterized in that selected from. The method of claim 19, A method for producing a nanoporous carbon material comprising the magnetic nanoparticles by the organic-organic self-assembly method and the synthesis method in a single reaction vessel and using as a high performance ibuprofen drug adsorbent. The method according to claim 31, Method for producing a nanoporous carbon material comprising the magnetic nanoparticles for the high performance ibuprofen drug adsorbent and is separable by magnetic force in a solution. Organic materials are used as the leading material for forming carbon pore walls, block copolymers are used as structural forming templates, and self-assembly and carbonization processes are carried out in a single reaction vessel using a mixed solution containing a transition metal compound as a magnetic inorganic source. A method for producing a nanoporous carbon material comprising magnetic nanoparticles.

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