KR100954721B1 - A cleaning composition for bath comprising natural extract as effective components - Google Patents

Abstract

PURPOSE: A low toxic and low stimulus cleaning composition for bath is provided to reduce used amount of phosphoric acid and hydrochloric acid to minimum amount and to be effective for bacteria and mold. CONSTITUTION: A cleaning composition for bath uses ethanol as an extraction solvent and comprises 10.90-13.10 weight% orange oil or D-limonene of tangerine extract or organic acid of tangerine extract liquid; 9.90-11.10 weight% higher fatty acid of purified palm oil or palm extracts; 8.99-11.01 weight% alkanol amide; 6.05-8.35 weight% alkyl sulfonate or alkyl benzene sulfonate; 5.97-8.03 weight% hydroxypropyl methyl cellulose, 2.65-4.95 weight% polyether polyol, 0.21-0.63 weight% hydrochloric acid, and 0.49-0.79 weight% water.

Description

A cleaning composition for bath comprising natural extract as effective components

The present invention relates to a toilet and bathroom cleaning composition excellent in antimicrobial activity containing a natural extract, more specifically, by combining together natural extracts, such as citrus extract and palm extract, low toxicity effective for breeding oily bacteria, bacteria, fungi And hypoallergenic cleaning compositions for bathrooms and toilets.

In general, since toilets and bathrooms have a large amount of microorganisms such as bacteria or sanitary dirty malignant contaminants, they should be kept in a sanitary state by using a cleaning agent that exerts an effect such as sterilization, bleaching and odor removal. The conventional toilet or bathroom cleaner used in the prior art is mostly made of hydrochloric acid (HCl), which is a kind of strong acid in consideration of the disinfection and sterilization action of the microorganisms. However, while hydrochloric acid has a sterilizing action based on strong oxidizing power and its disinfecting effect, it not only causes strong corrosion, but also inevitably causes dermatitis and odor due to skin contact during use. In addition, the existing three tablets for toilet or bathroom is diluted with hard water to produce a white precipitate when used, the stain is formed after use, the sediment remains as it is, as well as the cleaning effect is significantly reduced, the water quality for dilution is limited problem There was this. In addition, the use standard in the Occupational Safety and Health Act indicates that phosphoric acid and hydrochloric acid should each satisfy less than 1%.

Efforts have been made to provide a cleaning composition for malignant contaminants dedicated to toilets or bathrooms to solve the problems of such existing cleaning agents.

Indeed, the present inventors also provide a cleaning composition combining various compounds and additives in specific proportions, so that no white precipitates or stains occur even when diluted with various water qualities, excellent cleaning ability against puncture, no corrosion to the base material, and excellent gloss. The invention of the cleaning composition for the toilet for exerting the effect was completed and disclosed as Patent Registration No. 10-0543213. However, as a result of reducing the amount of hydrochloric acid and phosphoric acid, the sterilization effect is insufficient for use in bathrooms and toilets that absolutely require a sterilization effect.

This can be clearly seen in the 2007 Research Report on Pathogens Residing in Public Restrooms, published by Prof. Jong-Sik Chun (School of Life Sciences, Prokaryotic Microbiology and Bioinformatics Laboratory, Seoul National University). An average of 710,000 bacteria (3800 per 10 cm 2) were detected in Western-style toilets in five restrooms, with the largest number being 2 million (10,000 per 10 cm 2) and the least 130,000 (10). 670 per cm 2), which is 44 times larger than the subway handle (86 per 10 cm 2) and 11 times as large as the toilet handle (340 per 10 cm 2). The result is contaminated.

In particular, a total of 31 bacteria were detected, and eight of them correspond to 'opportunistic bacteria' that can cause disease in patients with weakened immunity or the elderly, and among the opportunistic bacteria, acintobacter and staphylococci, respectively. It was detected in three and five places, and there were also E. coli found in contaminated feces.

For reference, there is a general bacterium tolerance level for drinking water (100 per 1ml), wet tissue (2500 per 1g), and a wet towel (100,000 per sheet), but there are no bacterial standards for toilets. Even in view of this, there is an urgent need to develop a cleaner that can give antibacterial activity as well as sterilize bacteria present in toilets or bathrooms such as opportunistic infectious bacteria.

Accordingly, the present inventors continue to research to improve the above-mentioned problems by combining natural extracts such as citrus extract and palm extract together, low toxicity and hypoallergenic detergents for bathroom and toilet effective in breeding oily bacteria, bacteria, fungi It has been found that the present invention can be provided and the present invention has been completed.

According to the present invention, ethanol is used as the extraction solvent, and 10.90 to 13.10% by weight of the organic acid of natural orange oil or D-limonene or citrus extract in the citrus extract, and 9.90 to 11.10% by weight of the higher fatty acid of the refined palm oil or palm fruit extract in the palm extract. %, Alkanolamide 8.99 to 11.01%, alkylsulfonate or alkylbenzenesulfonate 6.05 to 8.35%, hydroxypropyl methylcellulose 5.97 to 8.03%, polyetherpolyol 2.65 to 4.95%, hydrochloric acid 0.21 to 0.63% It provides a toilet and bathroom cleaning composition excellent in antimicrobial activity containing a natural extract comprising a%, 0.49 to 0.79% by weight of phosphoric acid and the residual amount of water.

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According to the present invention, it has the advantage of providing a low-toxic and hypo-allergenic detergent composition for bathrooms and toilets effective in breeding oily contaminants, bacteria, and fungi while reducing the amount of hydrochloric acid and phosphoric acid to a very small amount.

Hereinafter, the present invention will be described in detail.
Citrus extract not only has excellent removal ability of pollutants, especially oily pollutants, but also effectively prevents the growth of bacteria and fungi, along with odor removal and fragrance effects.
In particular, as shown in the following examples in which the antimicrobial effect was specifically prepared by adding each strain to each of the 10 strains against the ethanol extract in the citrus extract, the citrus ethanol extracts were L. monocytogenes ATCC 19114, B. cereus YUFE 2004 The antimicrobial activity of S. aureus KFCC 11764 and P. fluorescens KCTC 1645 were different depending on the concentration of the extract. For L. monocytogenes ATCC 19114, the antimicrobial effect was also increased depending on the concentration of the extract, up to 100-2000 ppm. It was confirmed that there is a growth inhibitory effect. In addition, B. cereus YUFE 2004 showed a significant antimicrobial effect of 100-1000ppm up to 36 hours in culture and 2000ppm up to 72 hours compared to the control. Also. The growth of S. aureus KFCC 11764 was delayed with the addition of 500-1000ppm extract, and the addition of 2000ppm showed excellent antibacterial effect. P. fluorescens KCTC 1645 showed almost similar inhibitory effect up to 100-2000 ppm and showed antimicrobial effect without being significantly affected by the concentration of extract.
As well as the ethanol extract, fractions fractionated with chloroform, ethyl acetate, butanol also confirmed antimicrobial activity against all 10 strains.
At this time, the citrus extract can be used as an extract obtained from at least one of the leaves, peel and fruit of the citrus fruits, and the kind thereof may be natural orange oil, D-limonene or organic acid of the extract. Although it is also possible to use as a weakly alkaline hypoallergenic inorganic cleaner, metasilicates can not only solubilize organic acids in citrus fruits, especially extracts, but also remove inorganic contaminants in bathrooms and toilets.
Not only that, when the palm extract is blended together as a natural extract, it improves the antimicrobial activity deficient in the tangerine extract along with the tangerine extract, and synergistically exerts cleaning power, coating film formation, odor removal, and gloss effect.
Such palm extract is an extract obtained from at least one of palm leaves, bark and fruit, and it is sufficient to use higher fatty acids of refined palm oil or palm fruit extract as its kind.
In addition, ethanol extracts for palms are also shown in the following examples, the following 10 strains, Listeria monocytogenes ATCC 15313, 19111, 19112, 19113, 19114, Bacillus cereus YUFE 2004, Staphylococus aureus KFCC 11764, P. Fluorescencs 1645, 2322 In comparison with Leuconostoc mesenteroides KFCC 12031, the antimicrobial activity was shown to have a clear anti-proliferative effect, and the extract with a clear antimicrobial effect was identified by fractionation with chloroform, ethyl acetate and butanol. I could confirm it.
The blending amount of the citrus extract and palm extract is preferably 10.90 to 13.10% by weight and 9.90 to 11.10% by weight relative to the total weight of the cleaning composition to be prepared, thereby providing synergistic antimicrobial activity. In addition, the concentration of the tangerine and palm extract is not limited to this, it is sufficient to use a concentration of about 10% respectively.
In addition to the mixture of the extracts, it is preferred to include vegetable surfactants, surfactants, hydroxypropyl methylcellulose, polyetherpolyols, hydrochloric acid, phosphoric acid and water.
At this time, the vegetable surfactant is not limited thereto, but it is sufficient to use alkanolamide, and the content thereof is preferably used within the range of 8.99 to 11.01% by weight based on the total weight of the cleaning composition. When mixed with and used by microorganisms in water is fast (biodegradation) is the optimal amount of water considering the role that can reduce the water pollution due to the small load of water pollution by drainage after washing.
In addition, the surfactant may be used as any component known to increase the cleaning power and lower the surface tension, alkyl sulfonate or alkylbenzene sulfonic acid having 10 to 20 carbon atoms as a higher alcohol-based or anionic surfactant It is more preferable to use a salt or a polymer amine, and considering the amount of use of the vegetable surfactant, etc., the amount of the surfactant to the total weight of the cleaning composition is preferably within the range of 6.05 to 8.35% by weight.
Meanwhile, in the present invention, the polyether polyol and the hydroxypropyl methyl cellulose are a kind of nonionic surfactants, and are added separately from the general surfactants to double the washing power, and thus, polyether polyols and hydroxy. When the content of propyl methyl cellulose exceeds 4.95% by weight and 8.03% by weight, respectively, there is a problem in that the production cost is increased and the productivity is lowered. For each compounding quantity, it is sufficient if it exists in the range of 5.97 to 8.03 weight% of hydroxypropyl methylcellulose, and 2.65 to 4.95 weight% of polyether polyol.
In addition, the hydrochloric acid is a component included in most of the existing detergents to perform disinfection and bleaching action based on the strong acid characteristics of pH 2 or less, but must be mixed with other components in the following optimum composition ratio than conventional cleaners While significantly lowering the amount of hydrochloric acid, it can exert an excellent effect than any other conventional products in sterilization and cleaning effects. The hydrochloric acid content has the advantage of exerting an excellent effect on the disinfection, bleaching, washing and glossing effects even at a very small amount of 0.21 to 0.63% of the total weight of the cleaning composition. Specifically, when the amount of hydrochloric acid exceeds 0.63% of the concentration, the corrosion, oxidizing power, and skin irritation are remarkably increased. If the concentration of hydrochloric acid is less than 0.21%, the sterilization and gloss effect are deteriorated. There was a problem.
The phosphoric acid, when mixed with hydrochloric acid, not only exerts an excellent cleaning and gloss effect, but also softens hard water in which the cleaning agent is not easily dissolved, thereby making it possible to use the cleaning agent in various water qualities.
When diluting the existing detergents with hard water, white precipitates are generated, and stains and precipitates remain after washing, and the cleaning power is remarkably lowered. In the present invention, since the hard water is softened by the addition of phosphoric acid, Not only does it cause problems of stains and sediment or deterioration of cleaning power, but also has the advantage of using a minimum amount of water, which is also hardened by adding a small amount of 0.49 to 0.79% of the total weight of the cleaning composition. And with the advantage of providing an environmentally friendly product while maximizing the effect of improving the cleaning power. Specifically, when the phosphoric acid content exceeds 0.79% of the concentration, the oxidizing power may be lowered. If the phosphoric acid content is less than 0.49% of the concentration, the sterilization and gloss effects are deteriorated.
As the remainder, when water such as purified water is used, a liquid washing liquid is provided.
In addition, octadecyltrimethoxysilane can be added. The octadecyltrimethoxysilane acts as an emulsifying antifoaming agent to reduce the incorporation of foam and to remove bubbles generated during dilution, and to allow other components to be uniformly mixed and to enhance dispersibility in use. Besides, antifoaming agents such as silicone oil, silicone oil in which micelle silica powder is dispersed, paraffin oil and the like can also be used.
As described above, 10.90 to 13.10% by weight of the citrus extract, 9.90 to 11.10% by weight of the palm extract, 8.99 to 11.01% by weight of the vegetable surfactant, 6.05 to 8.35% by weight of the surfactant, hydroxypropyl methylcellulose 5.97 To 8.03% by weight, 2.65 to 4.95% by weight of polyether polyol, 0.21 to 0.62% by weight of hydrochloric acid, 0.49 to 0.90% by weight of phosphoric acid, and the remaining amount of water, has excellent antibacterial activity containing natural extracts, and a separate pigment or perfume component. In addition to the need for sterilization, cleaning, bleaching and gloss, it maximizes skin and mucous membrane stability, and chemical products such as hydrochloric acid and phosphoric acid are used in an extremely small amount or in an extremely small amount to provide an environmentally friendly product.
Hereinafter, the cleaning composition of the present invention will be described in more detail with reference to examples. However, each of the embodiments is only an example to help understanding of the present invention and does not limit the scope of the present invention.

< Experimental Example  Antimicrobial Activity of 1-Citrus and Palm Extracts>

Citrus and Palm Ethanol Extract Preparation

Grind 100 g each of tangerine peel and palm skin finely with a grinder, mix 75% ethanol with about 5 times of the ground weight, and place it in a flask attached with a reflux condenser. Heat and extract for 3 hours in an 85 ℃ water bath. After filtration, ethanol was evaporated in a rotary vacumn evaporator to obtain a concentrate. The soluble solid content contained in each concentrate was taken as 1 ml of the concentrate and dried at 105 ° C. to obtain evaporation residue.

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Use strain  And badge

The strains used in this experiment were psychrotrophs and strains that could cause food poisoning and microorganisms involved in decay, and the specific medium used for each strain is summarized in Table 1 below.

Each strain cultured in slant was inoculated in platinum, inoculated in 10 ml of the corresponding medium, incubated at 30 ° C. for 24 hours, 0.1 ml of the activated solution was injected into a dry plate overnight at room temperature, and then uniformly applied with a bent glass rod. Sterilized 0.65mm filter paper disc (Whatmann No. 2) was immersed in each extract, absorbed and dried. The disc was placed on the plate plate inoculated with bacteria, incubated at 30 ℃ for 24-48 hours, and then The diameter of the surrounding clear zone (mm) was compared. Each disc tested was found to be dry and adsorbed dry matter.

Inhibition Concentration of Ethanol Extract

The concentrate was sterilized by a membrane filter (0.2 μm, pore size), and the liquid medium was added at each concentration (ppm) based on the solid content of each extract, and then inoculated with 0.1 ml of the activated culture solution at 30 ° C. Microbial proliferation was compared by absorbance at 620 nm with a spectrophotometer (Cecil se 292, England) every 12 hours while incubated for 3 days at.

Fraction of ethanol extract

The crude extract obtained by extraction with 75% ethanol was sequentially fractionated with chloroform, ethyl acetate and butanol, and then concentrated, respectively, to obtain a fraction of each solvent. Finally, a water layer was concentrated and concentrated to observe the effect of inhibiting growth on each concentrate. To prepare.

Antimicrobial Investigation of Ethanol Extracts

As a result of examining the antimicrobial activity of the ethanol extract of the citrus and palm, it is as summarized in Table 2.

Classification Bacteria ^{1 )} Clear Zone Diameter (mm) SS ²⁾ One 2 3 4 5 6 7 8 9 10 Citrus Extract 16 15 13 15 16 19 18 19 16 15 1.3 Palm extract 17 16 16 10 19 18 17 14 18 14 1.7

¹⁾ See Table 1.

²⁾ mg of soluble solid content of extract / disc.

Antimicrobial Effect of Ethanol Extracts at Different Concentrations

The citrus ethanol extract was added to each of the 10 strains for each antimicrobial effect by the concentration, as a result, the citrus ethanol extract is L. monocytogenes ATCC 19114, B. cereus YUFE 2004, S. aureus KFCC 11764 and P. It can be seen that the antimicrobial activity of fluorescens KCTC 1645 varies depending on the concentration of the extract. For L. monocytogenes ATCC 19114, the antimicrobial effect increases according to the concentration of the extract. . B. cereus YUFE 2004 showed a significant antimicrobial effect of 100-1000ppm up to 36 hours of culture and 2000ppm up to 72 hours compared to the control. Also. The growth of S. aureus KFCC 11764 was delayed with the addition of 500-1000ppm extract, and the addition of 2000ppm showed excellent antibacterial effect. P. fluorescens KCTC 1645 showed almost similar inhibitory effect up to 100-2000 ppm and showed antimicrobial effect without being significantly affected by the concentration of extract.

Of extract By fraction  Antimicrobial activity

As an initial stage of the separation of antimicrobial substances, chloroform, ethyl acetate, butanol, and other solvents were sequentially separated to search for antimicrobial activity and the results are summarized in Table 3 below.

As shown in Table 3, for each strain, citrus fractions showed uniform antibacterial effect, and palm fractions showed distinct antibacterial effect in ethyl acetate fraction.

Especially 10 strains, Listeria monocytogenes ATCC 15313, 19111, 19112, 19113, 19114, Bacillus cereus YUFE 2004, Staphylococus aureus KFCC 11764, P. Fluorescencs 1645, 2322 and Leuconostoc As a result of comparing antimicrobial activity against mesenteroides KFCC 12031, both tangerines and palms showed distinct anti-proliferative effects against each strain, and most strains were identified by fractionating extracts with distinct antimicrobial effects into chloroform, ethyl acetate and butanol. Citrus and palm extracts showed higher antimicrobial activity in the ethyl acetate fraction.

< Experimental Example  2-composition composition and physical properties comparison>

Example  One

13.10% by weight citrus ethanol extract, 11.10% by weight palm ethanol extract, 11.01% by weight alkanolamide, 8.35% by weight alkylbenzenesulfonate having 10 carbon atoms, hydroxypropyl methylcellulose 8.03% by weight, 4.95% by weight of polyether polyol, 1.8% by weight of hydrochloric acid (35% concentration) (0.63% in terms of conversion), 0.98% by weight of phosphoric acid (80% concentration) (0.79% in terms of conversion) Stir for 1 minute to make a uniform solution. The solution was tested for detergency, stability, detergency, skin irritation, corrosive oxidation, and antimicrobial activity.

Example  2

10.90% by weight of citrus ethanol extract, 9.90% by weight of palm ethanol extract, 8.99% by weight of alkanolamide, 6.05% by weight of alkylsulfonate having 20 carbon atoms, hydroxypropyl methylcellulose 5.97 % By weight, polyether polyol 2.65% by weight, hydrochloric acid (35% concentration) 0.6% by weight (0.63% in terms of conversion), phosphoric acid (80% concentration) 0.61% by weight (0.49% in terms of conversion) Stir for minutes to prepare a homogeneous solution. The solution was tested for detergency, stability, detergency, skin irritation, corrosive oxidation, and antimicrobial activity.

Comparative example  One

7.20 wt% hydrochloric acid (35% concentration), phosphoric acid (80% concentration) 3.80 wt%, dodecylsulfonate 11.00 wt%, alkanolamide 12.00 wt%, polyetherpolyol 5.50 wt% 7.50% by weight of oxypropyl methylcellulose, 1.50% by weight of silicone oil, 0.10% by weight of food red No. 2 known as a colorant and 51.40% by weight of water, and then stirred for about 1 minute to prepare a uniform solution. The solution was tested for detergency, stability, detergency, skin irritation, corrosive oxidation and antimicrobial activity.

Comparative example  2

7.25% by weight hydrochloric acid (35% concentration), 3.85% by weight phosphoric acid (80% concentration), 11.02% by weight dodecylsulfonate, 12.02% by weight alkanolamide, 5.50% by weight polyetherpolyol 7.50% by weight of oxypropyl methylcellulose, 1.50% by weight of silicone oil, known as colorant

0.10% by weight of food red pigment (Food Red No. 2) and 51.26% by weight of water were added, followed by stirring for about 1 minute to prepare a uniform solution. The solution was tested for detergency, stability, detergency, skin irritation, corrosive oxidation, and antimicrobial activity.

Comparative example  3

7.15% by weight hydrochloric acid (35% concentration), 3.75% by weight phosphoric acid (80% concentration), 7.50% by weight hydroxypropyl methylcellulose, 1.50% by weight silicone oil, edible red pigment known as colorant Food Red No. 2) 0.10% by weight and 51.54% by weight of water are added, followed by stirring for about 1 minute to prepare a uniform solution. The solution was tested for detergency, stability, detergency, skin irritation, corrosive oxidation, and antimicrobial activity.

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For reference, the antimicrobial activity test is described in LJ Vinson et al., J. Pharm. Sci., 50 827-830, 1961] was performed according to the Calfskin Test method reported in the following eight strains- S. aureus ATCC9144, S. faecalis ATCC10541, E. coli ATCC 10536, S. typhi The degree of incubation for NCTC 786, S. choleraesius ATCC10708, P. vulgaria ATCC 6896, P. mirabilis ATCC 14153, and K. kneumoniae ATCC 4352 was determined in five stages from 0 (no growth inhibition) to 4 (to completely inhibit growth). Grading was performed to show the active effect.

Comparative experiment results of the Examples and Comparative Examples are shown in Table 4.

Property classification Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Cleaning power Great Great Great Great Great Mixed / Stability stability stability stability stability stability Detergency Great Great Great Great Great Skin irritation none none usually none none Corrosion Oxidation none none none none none Antimicrobial activity 4 3 0 0 One

As shown in Table 4, the cleaning composition according to the comparative example was also excellent in terms of cleaning power, mixing / stability, cleaning, skin irritation, corrosion oxidation, but in the case of the cleaning composition having a composition of the present invention in addition to antibacterial It was confirmed that the activity is also very good.

According to the present invention, it is possible to provide a low-toxic and hypo-allergenic detergent composition for bathrooms and toilets, which contains little amount of hydrochloric acid and phosphoric acid, and is effective for breeding oily contaminants, bacteria, and fungi.

Claims (7)

Ethanol is used as the extraction solvent, 10.90 to 13.10% by weight of natural orange oil or D-limonene or citrus extract in citrus extract, 9.90 to 11.10% by weight of higher fatty acids in refined palm oil or palm fruit extract in palm extract, alkanolamide 8.99 to 11.01% by weight, 6.05 to 8.35% by weight of alkylsulfonate or alkylbenzenesulfonate, 5.97 to 8.03% by weight of hydroxypropyl methylcellulose, 2.65 to 4.95% by weight of polyetherpolyol, 0.21 to 0.63% by weight hydrochloric acid, 0.49 to phosphoric acid A composition for cleaning toilets and bathrooms having excellent antibacterial activity, comprising a natural extract comprising 0.79% by weight and a residual amount of water. delete delete delete delete delete delete