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KR100576074B1 - Feed Additives for Decreasimg Somatic Cell Count of Lactating Dairy Cow and Production Method of Milk from The Cow - Google Patents

Feed Additives for Decreasimg Somatic Cell Count of Lactating Dairy Cow and Production Method of Milk from The Cow Download PDF

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Publication number
KR100576074B1
KR100576074B1 KR1020040013621A KR20040013621A KR100576074B1 KR 100576074 B1 KR100576074 B1 KR 100576074B1 KR 1020040013621 A KR1020040013621 A KR 1020040013621A KR 20040013621 A KR20040013621 A KR 20040013621A KR 100576074 B1 KR100576074 B1 KR 100576074B1
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South Korea
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weight
cow
somatic cell
milk
cell count
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KR1020040013621A
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KR20050087916A (en
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김현섭
정하연
백광수
이현준
기광석
정석근
안병석
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대한민국
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    • AHUMAN NECESSITIES
    • A42HEADWEAR
    • A42BHATS; HEAD COVERINGS
    • A42B1/00Hats; Caps; Hoods
    • A42B1/24Hats; Caps; Hoods with means for attaching articles thereto, e.g. memorandum tablets or mirrors
    • AHUMAN NECESSITIES
    • A42HEADWEAR
    • A42BHATS; HEAD COVERINGS
    • A42B1/00Hats; Caps; Hoods
    • A42B1/004Decorative arrangements or effects
    • AHUMAN NECESSITIES
    • A42HEADWEAR
    • A42BHATS; HEAD COVERINGS
    • A42B1/00Hats; Caps; Hoods
    • A42B1/18Coverings for protecting hats, caps or hoods against dust, rain, or sunshine
    • AHUMAN NECESSITIES
    • A42HEADWEAR
    • A42BHATS; HEAD COVERINGS
    • A42B1/00Hats; Caps; Hoods
    • A42B1/22Hats; Caps; Hoods adjustable in size ; Form-fitting or self adjusting head coverings; Devices for reducing hat size
    • A42B1/225Hats; Caps; Hoods adjustable in size ; Form-fitting or self adjusting head coverings; Devices for reducing hat size with openings for hair

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  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)

Abstract

본 발명은 강황 0.1∼50중량%, 감초 0.1∼50중량%, 황금 0.1∼30중량%, 금은화 0.1∼40중량%, 연교 0.1∼50중량%, 유기아연 1∼60중량%, D-아미노-레불렌산(ALA) 0.001∼10중량%, 및 말분 15∼50중량%을 포함함을 특징으로 하는 젖소에서 착유한 우유 내의 체세포수 저감용 사료첨가제를 제공한다.The present invention is 0.1 to 50% by weight of turmeric, 0.1 to 50% by weight licorice, 0.1 to 30% by weight of gold, 0.1 to 40% by weight of gold and silver, 0.1 to 50% by weight of bridge, 1 to 60% by weight of organic zinc, D-amino- Provided is a feed additive for reducing somatic cell count in milk milked from cows comprising 0.001 to 10% by weight of levurenic acid (ALA) and 15 to 50% by weight of powder.

또한, 본 발명은 영양조절급여에 의하여 최적의 젖소 생리상태를 유지하면서 젖소에서 착유한 우유 내의 체세포수를 최소화함으로써 젖소의 생산성을 향상시킬 수 있는 상기 체세포 저감용 사료첨가제를 젖소에 급여하고, 상기 젖소로부터 체세포가 저감된 우유를 생산하는 방법을 제공한다.In addition, the present invention is to feed the cow with the somatic cell feed additives that can improve the productivity of the cow by minimizing the somatic cell count in the milk milked from the cow while maintaining the optimal cow physiological state by nutritional control benefits, Provided are methods for producing milk with reduced somatic cells from cows.

체세포수, 저감용, 첨가제Somatic cell count, reduction, additive

Description

생리활성을 촉진하여 젖소에서 착유한 우유 내의 체세포수를 저감하는 젖소용 사료첨가제{Feed Additives for Decreasimg Somatic Cell Count of Lactating Dairy Cow and Production Method of Milk from The Cow}Feed Additives for Decreasimg Somatic Cell Count of Lactating Dairy Cow and Production Method of Milk from The Cow}

본 발명은 젖소에 급여하는 사료첨가제에 관한 것으로, 보다 상세하게는 영양조절급여에 의하여 최적의 젖소 생리상태를 유지하면서 젖소에서 착유한 우유 내의 체세포수를 최소화함으로써 젖소의 생산성을 향상시킬 수 있는 체세포 저감용 사료첨가제 및 이를 젖소에 급여하여 체세포가 저감된 우유를 생산하는 방법에 관한 것이다.The present invention relates to a feed additive to be fed to cows, more specifically somatic cells that can improve the productivity of cows by minimizing the number of somatic cells in milk milked from cows while maintaining the optimal cow physiological state by nutritional control The present invention relates to a feed additive for abatement and a method of producing milk having reduced somatic cells by feeding it to cows.

젖소 사육농가에서 늘 상존하며 많은 경제적 손실을 주는 것으로 체세포수 증가와 유방염의 발생을 들 수 있다. 이는 젖소의 전 생애 동안 늘 발생할 수 있는 소모적인 질병의 일종이다. 이를 줄이기 위해 영양학자 및 수의학자들은 다양한 첨가제, 항생제 및 치료 기술들을 개발하여 왔으며, 이로 인해 많은 개선이 있었으나 아직도 국내 젖소농가의 약 70%는 2등급 이하의 우유로 젖소에서 착유한 우유 내의 체세포수 개선의 여지가 많이 남아 있다. 젖소에서 착유한 우유 내의 체세포수 및 유방염의 발생을 줄이기 위해 지금까지 여러 분야에서 시도한 결과를 살펴보면, 우선 사육환경 및 착유위생 개선에 의하여 젖소에서 착유한 우유 내의 체세포수 및 유방염의 발생을 줄이기 위해 HACCP 및 CCP를 접목하고 있으며, 이로 인하여 환경성 및 전염성 유방염 원인균의 발생을 어느 정도 줄이는데 기여하고 있다.Persistent economic losses in dairy cattle farmers include increased somatic cell counts and the development of mastitis. It is a kind of wasting disease that can occur throughout the life of the cow. To reduce this, nutritionists and veterinarians have developed a variety of additives, antibiotics and therapeutic techniques, which have led to many improvements, but still about 70% of domestic dairy farmers are cows milked from cows milked with cows of grade 2 or less. There is much room for improvement. In order to reduce the somatic cell count and mastitis in milk milked from cows, the results of several attempts have been made so far. First, HACCP is used to reduce the incidence of somatic cell count and mastitis in cow's milk by improving the environment and milking hygiene. And CCP, thereby contributing to some extent in reducing the incidence of environmental and infectious mastitis causative organisms.

이와 더불어 착유시 개체간 전염에 의한 젖소에서 착유한 우유 내의 체세포수를 줄이기 위한 방법으로 요오드(I)가 주성분인 액체를 착유전후에 유두에 뿌려주거나 침지해 주는 방법이 있으며, 농가에서 현재 많이 사용하고 있는 첨가제로 외국에서 수입한 아연공급제인 진프로(Zn-Pro) 등을 사용하는 방법이 있다. 하지만 젖소의 젖소에서 착유한 우유 내의 체세포수 증가 및 유방염의 원인이 너무나 다양하여 현재 농가에서 많이 사용하고 있는 1∼2가지 성분을 함유하고 있는 첨가제로는 젖소의 유방염 및 체세포수 증가를 효율적으로 억제하기에는 한계가 있다. 특히 젖소에서 착유한 우유 내의 체세포수의 증가를 예방하는 차원에서 이를 원천적으로 줄이는데 관여하는 새롭고 다양한 영양조절 첨가제의 급여가 수반되어야 하지만 기존의 첨가제로는 농가에서의 체세포수 증가와 유방염 발생 억제를 효율적으로 대처하지 못하여 젖소 생산성 감소에 의한 경제적 손실에 직면하고 있다.In addition, as a way to reduce the number of somatic cells in milk milked from cows due to infection between individuals during milking, there is a method of spraying or immersing the liquid containing iodine (I) as the main ingredient before and after milking, and is widely used in farms. As an additive, there is a method using Zn-Pro, a zinc supplier imported from a foreign country. However, as the cause of somatic cell growth and mastitis in milk milked from cow's milk is so diverse, additives containing one or two ingredients currently used in farmhouses effectively suppress mastitis and somatic cell number increase in cow's milk. There is a limit to this. In particular, in order to prevent the increase of somatic cell counts in milk milked by cows, supplementation with new and diverse nutritional control additives involved in reducing the source should be accompanied. However, existing additives are effective in preventing somatic cell counts and mastitis in farms. As a result, they face economic losses due to reduced cow productivity.

젖소의 젖소에서 착유한 우유 내의 체세포수 및 유방염 발생의 감소를 위해서는 근본적으로 환경개선 뿐만 아니라 외부로부터 유방염 원인균의 유선내에서의 성장을 최소화하고 사멸효과를 높이기 위해 요구되는 젖소의 면역 및 대사기능을 최대화하도록 유도하여 궁극적으로 젖소에서 착유한 우유 내의 체세포수 및 유방염을 줄여줄 수 있는 적정 영양관리가 수반되어야 한다. 특히, 농가에서는 다양한 종류의 젖소에서 착유한 우유 내의 체세포수 감소제를 사용해 오고 있으나 실제 젖소에서 착유한 우유 내의 체세포수 감소에 의한 경제적 이익을 가져다 준 경우는 그리 많지 않다. 우리나라는 젖소에서 착유한 우유 내의 체세포수 등급에 의한 유대 가격차가 매우 크기 때문에, 이를 줄이기 위한 영양적 조절이 시도되었으나 근본적인 원인에 대한 해결 및 대책이 없이, 미봉적인 방어에만 초점을 두어 젖소에서 착유한 우유 내의 체세포수 저감을 위한 관리만을 해왔다. 따라서 젖소에서 착유한 우유 내의 체세포수 감소를 위한 새로운 종합적인 영양 및 생리조절 방법이 강구되어야 하는데, 이를 위한 방법으로 젖소의 영양, 면역 및 대사기능 촉진에 관여하는 영양소를 탐색하고 이를 보충하여 급여하는 종합 보조 첨가제의 개발이 필요하게 된다.In order to reduce somatic cell count and mastitis in milk milked in cow's milk, not only environmental improvement but also the immune and metabolic functions of cow's milk are required to minimize the growth in the mammary gland of mastitis causative organism from the outside and increase the killing effect. Proper nutrition should be involved to induce maximization and ultimately reduce somatic cell counts and mastitis in milk milked in cow's milk. In particular, farmers have been using somatic cell count reducing agents in milk milked from various types of cows, but not many cases have brought economic benefits by reducing somatic cell counts in milk milked from cows. In Korea, due to the large difference in the price of ties due to the somatic cell count in milk milked by dairy cows, nutritional control was attempted to reduce it, but without milking the cows by focusing on unprotected defenses without resolving the root cause. Only care has been taken to reduce somatic cell counts in milk. Therefore, a new comprehensive nutritional and physiological control method for reducing somatic cell count in milk milked from cows should be devised. For this purpose, the nutrients involved in promoting nutrition, immunity and metabolic function of cows are supplemented and supplemented. Development of comprehensive auxiliary additives is needed.

본 발명은 상기 종래기술이 가지는 문제를 해결하기 위해 안출된 것으로 그 주된 목적은 영양조절급여에 의하여 최적의 젖소 생리상태를 유지하면서 젖소에서 착유한 우유 내의 체세포수를 최소화함으로써 젖소의 생산성을 향상시킬 수 있는 체세포 저감용 사료첨가제를 제공함에 있다.The present invention has been made to solve the problems of the prior art as its main object is to improve the productivity of cows by minimizing the somatic cell count in milk milked from cows while maintaining the optimal cow physiological state by nutritional control It is to provide a feed additive for reducing somatic cells.

본 발명의 다른 목적은 영양조절급여에 의하여 최적의 젖소 생리상태를 유지하면서 젖소에서 착유한 우유 내의 체세포수를 최소화함으로써 젖소의 생산성을 향상시킬 수 있는 체세포 저감용 사료첨가제를 젖소에 급여하고, 상기 젖소로부터 체세포가 저감된 우유를 생산하는 방법을 제공함에 있다.Another object of the present invention is to feed the cow with somatic cell feed additives that can improve the productivity of the cow by minimizing the somatic cell count in the milk milked from the cow while maintaining the optimal cow physiological state by nutritional control, It provides a method for producing milk with reduced somatic cells from cows.

상기한 목적을 달성하기 위하여 본 발명은 강황 0.1∼50중량%, 감초 0.1∼50중량%, 황금 0.1∼30중량%, 금은화 0.1∼40중량%, 연교 0.1∼50중량%, 유기아연 1∼60중량%, D-아미노-레불렌산(ALA) 0.001∼10중량%, 및 말분 15∼50중량%를 포함함을 특징으로 하는 체세포수 저감용 사료첨가제를 제공한다.In order to achieve the above object, the present invention is 0.1-50% by weight of turmeric, 0.1-50% by weight of licorice, 0.1-30% by weight of gold, 0.1-40% by weight of silver and silver, 0.1-50% by weight of duct bridge, 1-60 of organic zinc. Provided is a feed additive for reducing somatic cell count, comprising: by weight, D-amino-levulinic acid (ALA) 0.001 to 10% by weight, and powder to 15 to 50% by weight.

본 발명은 바람직하게는 유기아연이 초산 킬레이트 아연인 것을 특징으로 하는 체세포수 저감용 사료첨가제를 제공한다.The present invention preferably provides a feed additive for reducing somatic cell count, wherein the organic zinc is chelated zinc acetate.

본 발명은 바람직하게는 상기 사료첨가제가 감미제 0.1∼5중량%를 더 포함함을 특징으로 하는 젖소에서 착유한 우유 내의 체세포수 저감용 사료첨가제를 제공한다.The present invention preferably provides a feed additive for reducing the somatic cell count in milk milked from cows, characterized in that the feed additive further comprises 0.1 to 5% by weight sweetener.

본 발명은 바람직하게는 상기 사료첨가제가 미생물제제를 더 포함함을 특징으로 하는 사료첨가제를 제공한다.The present invention preferably provides a feed additive, characterized in that the feed additive further comprises a microbial agent.

또한, 본 발명은 강황 0.1∼50중량%, 감초 0.1∼50중량%, 황금 0.1∼30중량%, 금은화 0.1∼40중량%, 연교 0.1∼50중량%, 유기아연 1∼60중량%, D-아미노-레불렌산(ALA) 0.001∼10중량%, 말분 15∼50중량% 및 감미제 0.1∼5중량%를 포함하는 젖소에서 착유한 우유 내의 체세포수 저감용 사료첨가제를 젖소에 급여하고, 상기 젖소로부터 체세포가 저감된 우유를 생산하는 방법을 제공한다.In addition, the present invention is 0.1-50% by weight turmeric, 0.1-50% by weight licorice, 0.1-30% by weight gold, 0.1-40% by weight silver gold, 0.1-50% by weight bridge, 1-60% by weight organic zinc, D- A cow was fed a feed additive for reducing the somatic cell count in milk milked from cows containing 0.001 to 10% by weight of amino-levulinic acid (ALA), 15 to 50% by weight of powder and 0.1 to 5% by weight of sweetener. It provides a method for producing milk with reduced somatic cells.

이하, 본 발명의 내용을 보다 상세하게 설명하면 다음과 같다.Hereinafter, the content of the present invention in more detail as follows.

본 발명에 따른 사료첨가제는 천연생리활성물질인 한약제로 유방염과 관계되는 염증 유발 단백질인 인터루킨-8 생성을 억제하여 염증을 예방하는 항염증 및 항산화작용을 하는 강황이 0.1∼50중량% 첨가된다. 0.1중량% 미만으로 첨가되는 경우에는 항염증 및 항산화작용을 기대하기 곤란하며, 50중량%를 초과하는 경우에는 초과에 따른 추가적인 상승효과를 기대하기 곤란하므로 상기 범위로 제한을 두는 것이 좋다.The feed additive according to the present invention is a natural physiologically active substance, which is added 0.1 to 50% by weight of turmeric which has anti-inflammatory and anti-oxidant activity to prevent inflammation by inhibiting the production of interleukin-8, an inflammation-inducing protein related to mastitis. When added in less than 0.1% by weight it is difficult to expect anti-inflammatory and antioxidant action, when it exceeds 50% by weight it is difficult to expect additional synergistic effects due to the excess is preferably limited to the above range.

감초는 항알러지, 항바이러스, 특히 체세포수 및 유방염의 주원인균인 포도상구균에 대한 억제력이 탁월하다. 감초는 0.1∼50중량% 첨가되며, 0.1중량% 미 만으로 첨가되는 경우에는 포도상구균에 대한 억제력이 충분하지 못하며, 50중량%를 초과하는 경우에는 초과에 따른 추가적인 상승효과를 기대하기 곤란하므로 상기 범위로 제한을 두는 것이 좋다.Licorice has excellent anti-allergic and antiviral properties, especially staphylococci, the main cause of somatic cell count and mastitis. Licorice is added 0.1 to 50% by weight, when less than 0.1% by weight is not enough to inhibit staphylococcus, if it exceeds 50% by weight it is difficult to expect additional synergistic effects due to the above range It is good to limit it.

황금, 금은화 및 연교는 항소염, 면역 증강 및 광범위 항균작용이 있다. 이들은 각각 황금 0.1∼30중량%, 금은화 0.1∼40중량%, 연교 0.1∼50중량% 첨가되며, 각각 0.1중량% 미만으로 첨가되는 경우에는 항소염, 면역증강 및 광범위한 항균작용을 기대하기 곤란하며, 상한선을 초과하는 함량의 투여는 추가적인 상승효과를 기대하기 곤란하므로 상기 범위로 각각 제한을 두는 것이 좋다. Gold, silver, and ducts have anti-inflammatory, immune-boosting and widespread antibacterial activity. They are added 0.1 to 30% by weight of gold, 0.1 to 40% by weight of gold and silver, and 0.1 to 50% by weight of duct bridge, respectively. If they are added less than 0.1% by weight, it is difficult to expect anti-inflammatory, immune enhancing and broad antibacterial activity. Administration of a content exceeding the upper limit is difficult to expect additional synergistic effect, so it is good to limit each of the above ranges.

특별히 한정하는 것은 아니지만, 바람직하게는 상기 제시된 한약제(강황, 감초, 황금, 금은화, 연교)는 사료첨가물의 중량 대비 총 5∼20중량% 정도 함유하는 것이 좋다.Although not particularly limited, preferably, the herbal medicines (turmeric, licorice, gold, silver and gold) presented above may contain a total of about 5 to 20% by weight based on the weight of the feed additive.

또한, 광물질로서 면역기능 개선 및 젖소에서 착유한 우유 내의 체세포수 감소를 위해 아연을 첨가한다. 아연은 소장에서의 이용효율을 높이기 위해 기존의 일반아연과 달리 유기아연, 보다 구체적으로는 반추위에서 분해되지 않고 소장에서 이용이 되도록 하여 이용효율을 높여준 초산-킬레이트 아연을 첨가한다. 초산-킬레이트 아연은 음이온인 초산을 양이온인 아연에 화학적으로 결합시킴으로써 용이하게 얻을 수 있다. 이러한 초산-킬레이트 아연은 현재 시판(이지바이오, 한국)되고 있는 것을 이용하거나, 직접 합성하여 사용할 수도 있으며, 1∼60중량% 첨가된다. 만일 1중량% 미만으로 첨가되는 경우에는 면역기능개선 및 젖소에서 착유한 우유 내의 체세포수 감소를 기대하기 곤란하며, 60중량%를 초과하는 경우에는 추가적인 상승효과를 기대하기 곤란하므로 상기 범위로 각각 제한을 두는 것이 좋다.In addition, zinc is added as a mineral to improve immune function and to reduce somatic cell count in milk milked in cow's milk. In order to increase the utilization efficiency in the small intestine, unlike conventional zinc, organic zinc, more specifically, zinc acetate-chelated zinc, which is used in the small intestine to be used rather than decomposed in the rumen, is added. Acetic acid-chelated zinc can be easily obtained by chemically bonding acetic acid, an anion, to zinc, a cation. Such acetic acid-chelated zinc may be used currently commercially available (Easy Bio, Korea), or may be directly synthesized, and 1 to 60% by weight is added. If it is added less than 1% by weight, it is difficult to expect improved immune function and reduced somatic cell count in milk milked from cows, and if it exceeds 60% by weight it is difficult to expect additional synergistic effects, so limited to each of the above range It is good to leave.

D-아미노-레불렌산(D-amino-levulenic acid, ALA)은 헤모글로빈의 합성증가에 의한 에너지대사 활성 및 T 세포와 대식세포 등의 활성화에 의한 면역물질 분비를 촉진한다. 이의 첨가량은 0.001∼10중량%이며, 0.001중량% 미만에서는 에너지 대사활성은 물론이거니와 면역물질 분비능에 미치는 영향이 매우 미미하여 적용이 곤란하며, 10중량%를 초과하는 경우에는 추가적인 상승효과를 기대하기 곤란하므로 상기 범위로 각각 제한을 두는 것이 좋다.D-amino-levulenic acid (DLA) promotes the release of immune metabolism by the activation of energy metabolism and the activation of T cells and macrophages, such as the synthesis of hemoglobin. Its addition amount is 0.001 to 10% by weight, and less than 0.001% by weight, as well as the energy metabolic activity and the effect on the secretion of the immune substance is very small, it is difficult to apply, if it exceeds 10% by weight it is difficult to expect additional synergistic effect Therefore, it is good to limit each of the above ranges.

말분은 15∼50중량% 범위내에서 캐리어(carrier)로서 첨가된다. 또한, 기호성 증진을 위하여 감미제가 더 포함될 수 있으며, 바람직하게는 0.1∼5중량% 범위내에서 첨가되는 것이 좋다.The powder is added as a carrier within the range of 15 to 50% by weight. In addition, a sweetener may be further included in order to enhance palatability, and it is preferable to be added within the range of 0.1 to 5% by weight.

또한, 상기 본 발명의 따른 사료첨가제는 기호성의 증진을 위하여 미생물 제제, 보다 구체적으로는 효모제를 더 포함할 수 있다. 미생물 제제는 특별한 한정을 요하는 것은 아니지만, 20∼30중량%의 범위내에서 첨가하는 것이 기호성 증진에 효과적이다.In addition, the feed additive according to the present invention may further include a microbial agent, more specifically, a yeast agent to enhance palatability. Although a microbial agent does not require a special limitation, it is effective to improve palatability by adding within 20-30 weight%.

하기 표 1에는 본 발명에 따른 젖소에서 착유한 우유 내의 체세포수 저감용 사료첨가제의 바람직한 실시예가 제시되어 있다. 상기 조성에 의하면 사료첨가제는 표 2에 제시된 바와 같이 kg당 영양소 함량이 건물 95.5%, 아연 2%, 셀레늄 0.01% 및 ALA 3g 및 기타 한약제가 함유되어 있는 천연생리활성물질이 일정량 혼합되어 있는 종합 복합 첨가제이다.Table 1 below shows a preferred embodiment of a feed additive for reducing somatic cell count in milk milked from cows according to the present invention. According to the composition, as shown in Table 2, the feed additive is a composite compound containing a certain amount of physiologically active nutrients containing 95.5% of dry matter, 2% of zinc, 0.01% of selenium, and 3 g of ALA and other herbal medicines. Additive.

<표 1> 젖소에서 착유한 우유 내의 체세포수 저감 첨가제의 구성비율Table 1: Composition ratio of somatic cell count reduction additives in milk milked from cows

구분division 구성비율(%)Composition ratio (%) kg당 혼합량Mixing weight per kg 한방제Herbal medicine 1010 100g100 g ·금은화Gold and silver coins (1)(One) (10)10 ·연교· Fellowship (2)(2) (20)20 ·강황·curcuma (2)(2) (20)20 ·황금·Gold (2)(2) (20)20 ·감초·licorice (2)(2) (20)20 ·갈근Root (1)(One) (10)10 유기아연(초산 킬레이트)Organic Zinc Acetate 3030 300g300 g 미생물제제Microbial agents 24.7724.77 247.7g247.7 g 아미노산(ALA)Amino acid (ALA) 0.030.03 0.3g0.3 g 말분Powder 3535 350g350 g 감미제Sweetener 0.20.2 2g2 g system 100100 1000g1000 g

<표 2> 젖소에서 착유한 우유 내의 체세포수 저감 첨가제의 영양소 함량<Table 2> Nutrient Content of Somatic Cell Reduction Additives in Milk Milked from Dairy Cows

구분division 체세포수 저감용 첨가제Somatic cell count reduction additive 영양소 함량(%)Nutrient content (%) ·건물(DM)Building (DM) 95.595.5 ·아연·zinc 22 ·SeSe 0.010.01 ·ALA(g)ALA (g) 33

상기 본 발명에 따른 사료첨가제는 젖소에서 착유한 우유 내의 체세포수가 높은 목장에서 두당 젖소에 약 20∼30g을 농후 사료나 TMR 사료에 혼합하여 급여할 수 있다.The feed additive according to the present invention may be fed by mixing about 20 to 30 g of cow's milk in soybean milk in a high somatic cell count in milk milked from cow's milk.

이하 본 발명의 내용을 실시예에 의해 보다 상세하게 설명하기로 한다. 다만 이들 실시예는 본 발명의 내용을 이해하기 위해 제시되는 것일 뿐 본 발명의 권리범위가 이들 실시예에 한정되어지는 것으로 해석되어져서는 아니된다.Hereinafter, the content of the present invention will be described in more detail with reference to Examples. However, these examples are only presented to understand the content of the present invention, and the scope of the present invention should not be construed as being limited to these embodiments.

<실시예 1><Example 1>

본 발명에 따른 젖소에서 착유한 우유 내의 체세포수 저감용 사료첨가제(표 1조성)의 효과를 조사하기 위한 시험을 축산연구소 낙농과 및 전국 14개 농장에서 2003년 8∼12월까지 약 4개월 동안 수행한 결과 첨가제 급여 전후 젖소에서 착유한 우유 내의 체세포수에 많은 차이가 있었는데, 그 주요 시험 결과는 다음과 같다. 축산연구소에서 수행한 시험축의 체세포수별 첨가제의 급여효과를 보면 젖소에서 착유한 우유 내의 체세포수가 20만 이하(1등급)의 개체는 첨가제의 급여 전후 체세포수의 감소는 2.1만으로 큰 차이가 없었으나, 젖소에서 착유한 우유 내의 체세포수가 높은 시험축의 경우 첨가제 급여 전후 큰 차이가 있었는데 20∼50만인 시험축의 경우 36.9만에서 16.2만으로 3등급에서 1등급으로, 50만∼100만인 시험축의 경우 75.6만에서 23.7만으로 4등급에서 2등급으로, 그리고 100만 이상의 시험축에서도 416.0에서 126.0만으로 현저하게 감소하는 경향을 보였으며 이때 급여기간은 30일, 급여량은 두당 20g 이었다.A test for investigating the effects of feed additives for reducing somatic cell counts in milk milked from cows according to the present invention (Table 1 composition) was conducted for 4 months from August 2007 to December 2003 in the Dairy Farm and 14 farms nationwide. As a result, there were many differences in the number of somatic cells in milk milked from cows before and after supplementation. The main test results are as follows. According to the feeding effect of somatic cell number additives from the livestock research institute, the decrease in somatic cell number before and after supplementation was 2.1 million for those with 200,000 or less somatic milk in milk milked from cows. There were significant differences before and after the supplementation for test shafts with high somatic cell counts in milk milked from cows. For test shafts of 20 to 500,000, from 36.9 to 16.2 million, from grade 3 to grade 1, and for test shafts with 500,000 to 1 million, 75.6 to 23.7 There was a tendency to decrease from grade 4 to grade 2 alone and over 1 million test shafts from 416.0 to 126.0 million. The pay period was 30 days and the amount was 20g per head.

(1) 첨가제 급여 효과(1) additive effect

-축산연구소-Livestock Research Institute

구분 division 젖소에서 착유한 우유 내의 체세포수(만/ml) Somatic cell count in milk milked from cows (million / ml) 산유량(kg/일) Production flow rate (kg / day) 급여전 Before pay 급여후 After salary 급여전 Before pay 급여후 After salary 20만 이하 200,000 or less 12.7 12.7 10.6 10.6 24.1 24.1 24.0 24.0 20∼50만 20-500,000 36.9 36.9 16.2 16.2 23.4 23.4 24.1 24.1 50만∼100만 500,000 to 1 million 75.6 75.6 23.7 23.7 22.9 22.9 24.4 24.4 100만 이상 1 million or more 419.0 419.0 126.0 126.0 22.6 22.6 24.8 24.8

-농가 급여효과-Farm Benefits

·젖소에서 착유한 우유 내의 체세포수 : 급여후 1등급 우유생산Somatic cell count in milk milked from cow: Grade 1 milk production after feeding

목장명Ranch Name 급여량(g)Salary (g) 두수(수)Head 체세포수 변화(만/ml)Somatic cell count change (million / ml) 급여기간 (일)Salary period (days) 비고Remarks 급여전Before pay 급여후After salary 구철회목장Old Iron Hall 3030 3232 50.050.0 14.014.0 3030 4 →1등급4 → 1st class 아산 H목장Asan H Ranch 2525 2020 50.950.9 14.214.2 3535 4 →1등급4 → 1st class 아산 S목장Asan S Ranch 2525 1919 45.045.0 14.214.2 3535 3 →1등급3 → 1st class 솔로몬Solomon 3030 2222 37.437.4 17.617.6 3030 3 →1등급3 → 1st class 혜진Hyejin 3030 5656 24.224.2 14.114.1 4040 2 →1등급2 → 1st class 한터Hanter 3030 2525 25.025.0 19.019.0 3030 2 →1등급2 → 1st class 구미 I목장Gumi I Ranch 2525 2525 23.423.4 15.615.6 3535 2 →1등급2 → 1st class system 7농가 (199두)7 farms (199 heads)

·젖소에서 착유한 우유 내의 체세포수 : 급여후 2등급 우유생산Somatic cell count in milk milked in cows: Grade 2 milk production after feeding

목장명Ranch Name 급여량(g)Salary (g) 두수(수)Head 체세포수 변화(만/ml)Somatic cell count change (million / ml) 급여기간 (일)Salary period (days) 비고Remarks 급여전Before pay 급여후After salary 김상돈목장Kim Sang Don Ranch 3030 2626 50.050.0 30.130.1 3030 4 →2등급4 → 2 grade 보은 D목장Boeun D Ranch 2525 3636 68.568.5 30.430.4 3535 4 →2등급4 → 2 grade 은자 목장Hermit ranch 3535 3434 49.149.1 25.725.7 88 3 →2등급3 → 2 grade 대일 목장Dale Ranch 3030 1717 37.037.0 24.024.0 1515 3 →2등급3 → 2 grade 서전 목장Seojeon Ranch 2525 1818 46.2346.23 29.929.9 1818 3 →2등급3 → 2 grade 한성만Han Sungman 3030 2828 35.035.0 28.028.0 1010 3 →2등급3 → 2 grade 서형은Suh 3030 2929 40.240.2 30.130.1 1515 3 →2등급3 → 2 grade system 7농가 (188두)7 farms (188 heads)

실제 농가 대상으로 급여한 시험 결과 전국적으로 총 14개 목장(공시 두수 총 387두)의 벌크우유 대상으로 시험한 결과 급여전에 4등급 목장이 1등급 목장으로 14.5%(2/14), 3등급 목장이 1등급 목장으로 14.5%(2/14), 2등급 목장이 1등급 목장으로 21.4%(3/14), 4등급 목장이 2등급 목장으로 14.5%(2/14), 그리고 3등급 목장에서 2등급 목장으로 35.7%(5/14)가 유질이 개선되어 본 발명에 따른 첨가제를 급여한 목장은 최소한 1등급 이상의 품질이 개선되는 획기전인 효과가 있었다. 이와 더불어 젖소에서 착유한 우유 내의 체세포수가 20만 이상인 시험축은 산유량도 증가되었는데 약 시험축별 체세포수의 차이에 따라 산유량이 0.7∼2.5kg의 효과가 있었다.As a result of the test for farm farmers, a total of 14 ranches (387 heads of cows) were tested nationwide. 14.5% (2/14) for this first grade ranch, 21.4% (3/14) for a first grade ranch, 14.5% (2/14) for a second grade ranch, and a third grade ranch The 25.7 ranch was improved by 35.7% (5/14) of oil quality, and the ranch supplemented with additives according to the present invention had a breakthrough effect of improving the quality of at least one grade or more. In addition, the milk yield increased in the test shafts with more than 200,000 somatic cells in milk milked by cows.

본 발명은 영양조절급여에 의하여 최적의 젖소 생리상태를 유지하면서 젖소에서 착유한 우유 내의 체세포수를 최소화함으로써 젖소의 생산성을 향상시킬 수 있다. 이에 따라, 최소한 전국 3-4 등급 농가(약 40%)를 기준으로 소득의 개선효과를 고려해 볼 때 약 135억원의 경제적 이익이 기대되며, 만일 2등급 농가를 기준으로 고려할 때에는 더욱 많은 경제적 이익을 기대할 수 있다.The present invention can improve the productivity of the cow by minimizing the somatic cell count in the milk milked from the cow while maintaining the optimal cow physiological state by nutritional control. As a result, at least 13.5 billion won in economic gains is expected in light of the improvement in income based on at least 3-4 country-level farmers (about 40%) nationwide. You can expect

Claims (6)

강황 0.1∼50중량%, 감초 0.1∼50중량%, 황금 0.1∼30중량%, 금은화 0.1∼40중량%, 연교 0.1∼50중량%, 유기아연 1∼60중량%, D-아미노-레불렌산(ALA) 0.001∼10중량%, 및 말분 15∼50중량%를 포함함을 특징으로 하는 젖소에서 착유한 우유 내의 체세포수 저감용 사료첨가제.Turmeric 0.1-50% by weight, licorice 0.1-50% by weight, gold 0.1-30% by weight, gold and silver coins 0.1-40% by weight, duct bridge 0.1-50% by weight, organic zinc 1-60% by weight, D-amino-levulinic acid ( ALA) A feed additive for reducing somatic cell count in milk milked from cows, comprising 0.001 to 10% by weight, and 15 to 50% by weight of powder. 제 1항에 있어서, 유기아연은 초산 킬레이트 아연인 것을 특징으로 하는 사료첨가제The feed additive of claim 1, wherein the organic zinc is chelated zinc acetate. 제 1항에 있어서, 감미제 0.1∼5중량%를 포함함을 특징으로 하는 젖소에서 착유한 우유 내의 체세포수 저감용 사료첨가제.A feed additive for reducing somatic cell count in milk milked from cows according to claim 1, characterized in that it comprises 0.1 to 5% by weight sweetener. 제 1항에 있어서, 미생물제제를 더 포함함을 특징으로 하는 사료첨가제The feed additive of claim 1, further comprising a microbial agent. 강황 0.1∼50중량%, 감초 0.1∼50중량%, 황금 0.1∼30중량%, 금은화 0.1∼40중량%, 연교 0.1∼50중량%, 유기아연 1∼60중량%, D-아미노-레불렌산(ALA) 0.001∼10중량%, 및 말분 15∼50중량%를 포함하는 젖소에서 착유한 우유 내의 체세포수 저감용 사료첨가제를 젖소에 급여하고, 상기 젖소로부터 체세포가 저감된 우유를 생산하는 방법. Turmeric 0.1-50% by weight, licorice 0.1-50% by weight, gold 0.1-30% by weight, gold and silver coins 0.1-40% by weight, duct bridge 0.1-50% by weight, organic zinc 1-60% by weight, D-amino-levulinic acid ( ALA) A method for producing a somatic cell reduced feed additive in milk milked from a cow comprising 0.001 to 10% by weight and 15 to 50% by weight of the cow, to produce milk with reduced somatic cells from the cow. 제 5항에 있어서, 유기아연은 초산 킬레이트 아연인 것을 특징으로 하는 방법6. The method of claim 5, wherein the organozinc is chelating zinc acetate.
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