JPS6360023B2 - - Google Patents
Info
- Publication number
- JPS6360023B2 JPS6360023B2 JP16563280A JP16563280A JPS6360023B2 JP S6360023 B2 JPS6360023 B2 JP S6360023B2 JP 16563280 A JP16563280 A JP 16563280A JP 16563280 A JP16563280 A JP 16563280A JP S6360023 B2 JPS6360023 B2 JP S6360023B2
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- mefluside
- tetrahydrofurfuryl
- chloride
- mol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 5
- QAHVHSLSRLSVGS-UHFFFAOYSA-N sulfamoyl chloride Chemical compound NS(Cl)(=O)=O QAHVHSLSRLSVGS-UHFFFAOYSA-N 0.000 claims description 5
- JCCBZCMSYUSCFM-UHFFFAOYSA-N 2-chlorobenzenesulfonamide Chemical compound NS(=O)(=O)C1=CC=CC=C1Cl JCCBZCMSYUSCFM-UHFFFAOYSA-N 0.000 claims description 3
- 238000000034 method Methods 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 description 3
- 239000012044 organic layer Substances 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- SCYULBFZEHDVBN-UHFFFAOYSA-N 1,1-Dichloroethane Chemical compound CC(Cl)Cl SCYULBFZEHDVBN-UHFFFAOYSA-N 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 229910021529 ammonia Inorganic materials 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- YBBRCQOCSYXUOC-UHFFFAOYSA-N sulfuryl dichloride Chemical compound ClS(Cl)(=O)=O YBBRCQOCSYXUOC-UHFFFAOYSA-N 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- MGFIMSHEGGIKMH-UHFFFAOYSA-N 2-chlorobenzenesulfonamide sulfurochloridic acid Chemical compound S(=O)(=O)(O)Cl.ClC1=C(C=CC=C1)S(N)(=O)=O MGFIMSHEGGIKMH-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 239000011260 aqueous acid Substances 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000005457 ice water Substances 0.000 description 1
- 239000012442 inert solvent Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- CWQAYJVEMMQWGM-UHFFFAOYSA-N n-methyl-1-(2-methyloxolan-2-yl)methanamine Chemical compound CNCC1(C)CCCO1 CWQAYJVEMMQWGM-UHFFFAOYSA-N 0.000 description 1
- YNOGYQAEJGADFJ-UHFFFAOYSA-N oxolan-2-ylmethanamine Chemical compound NCC1CCCO1 YNOGYQAEJGADFJ-UHFFFAOYSA-N 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Landscapes
- Furan Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16563280A JPS5788173A (en) | 1980-11-25 | 1980-11-25 | Preparation of mefruside |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16563280A JPS5788173A (en) | 1980-11-25 | 1980-11-25 | Preparation of mefruside |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5788173A JPS5788173A (en) | 1982-06-01 |
| JPS6360023B2 true JPS6360023B2 (zh) | 1988-11-22 |
Family
ID=15816045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16563280A Granted JPS5788173A (en) | 1980-11-25 | 1980-11-25 | Preparation of mefruside |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5788173A (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0242123A (ja) * | 1988-07-30 | 1990-02-13 | Mazda Motor Corp | 過給機付エンジンの制御装置 |
-
1980
- 1980-11-25 JP JP16563280A patent/JPS5788173A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0242123A (ja) * | 1988-07-30 | 1990-02-13 | Mazda Motor Corp | 過給機付エンジンの制御装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5788173A (en) | 1982-06-01 |
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