JPS6221324B2 - - Google Patents

Description

[Detailed description of the invention]

The present invention relates to a dentifrice composition suitable for use in a vertical pump type container, and more specifically, the dentifrice composition has a viscosity as low as 600 poise or less by incorporating igneous ultrafine powder amorphous silica. The present invention relates to a dentifrice composition that has good shape retention even when formed, has improved stringability, and is easy to extrude from a pump type container. Conventionally, toothpaste has generally been stored in a tube, and it has been easy to push it out from the tube.
Furthermore, the viscosity is usually set at 600 to 900 poise from the viewpoints of ease of putting it on a toothbrush, shape retention, threadability, etc. However, recently, various vertical pump-type containers have been proposed that allow toothpaste to be taken out simply by pressing a push-button or other push button (for example, Utility Model No. 54-34641; 55-38783, JP 57-68367, JP 68368, etc.),
Although it is desired to store and use toothpaste in these pump-type containers, conventional toothpaste formulations have too high a viscosity and are not suitable for storage and use in pump-type containers. That is, according to the studies of the present inventors, toothpaste for vertical pump type containers should have a viscosity of 600 poise or less, especially 200 to 500 poise, in order to improve extrudability due to the structure of the container. It is preferable that the toothbrush has such a low viscosity that it has excellent shape retention so that it does not lose its shape when placed on a toothbrush, and that there is no stringiness.
Excellent stringability is required, but conventional high-viscosity toothpaste formulations cannot be used due to their high viscosity;
If the pressure was set to 600 poise or less, the shape retention was poor, it easily ran off when placed on a toothbrush, and the stringiness was poor. For this reason, the present inventors conducted intensive research on dentifrice compositions suitable for use in vertical pump-type containers, and found that dentifrice compositions with 600 poise or less, which are easier to push out from the pump-type containers, It has been found that the above object can be effectively achieved by forming the composition preferably to have a viscosity of 200 to 500 poise and incorporating igneous ultrafine amorphous silica. That is, even if the present inventors tried to ensure the shape retention of toothpaste compositions using sodium carboxymethyl cellulose, carrageenan, etc., the shape retention was poor at low viscosity of 600 poise or less, and the shape retention was poor when placed on a toothbrush. Although it is difficult to maintain the silica powder, easily flows, and has poor spinnability, ultrafine igneous powder amorphous silica with an average primary particle diameter of 5 to 50 μm is added to the entire composition. 5% (weight%, same below)
By incorporating , the toothpaste composition has good shape retention even when formed to a low viscosity of 200 to 600 poise, does not lose its shape when taken out of the container and placed on a toothbrush, and does not cause stringiness. Therefore, it was found that a toothpaste composition that uses igneous ultrafine powder amorphous silica and retains its shape is effective as a toothpaste composition for use in a vertical pump type container that has good consistency and low viscosity. , which led to the present invention. The present invention will be explained in detail below. The dentifrice composition of the present invention includes an abrasive, a viscous agent, a binder, and if necessary, a surfactant, a sweetener, a flavoring agent,
Using preservatives, various active ingredients, and other ingredients,
Viscosity 200 to 600 poise, more preferably 200 to 500 poise (viscosity measured using a BH type viscometer at 25℃)
In this case, in the present invention, igneous ultrafine silica is used as the binder. Here, as the igneous ultrafine silica powder, one having an average primary particle diameter of 5 to 50 mμ, particularly 5 to 20 mμ is suitably used. In addition, igneous ultrafine powder amorphous silica has a specific surface area (BET method) of 100 to 450.
m ² /g and apparent specific gravity of 50 to 80 g/g are preferred. Examples of such igneous ultrafine powder amorphous silica include Aerosil manufactured by Degussa Corporation and
Examples include Cab-O-Sil. The content of the igneous ultrafine amorphous silica is preferably 1 to 5%, particularly 2 to 5%, based on the total composition. In the present invention, in addition to the igneous ultrafine amorphous silica, other binders such as carboxymethyl cellulose alkali metal salts,
Cellulose derivatives such as methylcellulose, hydroxyethylcellulose, sodium carboxymethylhydroxyethylcellulose, alkali metal alginates such as sodium alginate,
Gums such as propylene glycol alginate, carrageenan, xanthan gum, gum tragacanth, gum karaya, and gum arabic, synthetic binders such as polyvinyl alcohol, sodium polyacrylate, carboxyvinyl polymer, and polyvinylpyrrolidone, and inorganic binders such as aluminum silica gel and laponite. One or more types of agents can be blended. In this case, a dentifrice composition with good fluidity can be obtained by blending the thickening agent described below at a high concentration, particularly 10% or more, preferably 30 to 75% of the total composition. When preparing a dentifrice composition with a high content of thickening agent having good properties, carboxymethylcellulose alkali metal salts such as sodium carboxymethylcellulose are preferably added in an amount of 0.1 to 2%, particularly 0.5 to 1.2%, together with igneous ultrafine amorphous silica. It is preferable to add a thickening agent to the dentifrice composition, which can further improve the stringiness of the dentifrice composition. The dentifrice composition of the present invention contains an abrasive, a viscous agent, etc. as described above, and examples of these components include dicalcium phosphate dihydrate and dihydrate as an abrasive. anhydrous, monocalcium phosphate, tertiary calcium phosphate, calcium carbonate, calcium pyrophosphate, calcium sulfate, titanium oxide, alumina, hydrated alumina, silica-based abrasives such as precipitated silica and anhydrous alkali metal silicate complexes, aluminum silicate , insoluble sodium metaphosphate, insoluble potassium metaphosphate, tertiary magnesium phosphate, magnesium carbonate, bentonite, zirconium silicate, synthetic resin, etc., and one or more of these may be blended (the amount usually 0). ~50%, especially 10-30
%). In addition, as a silica-based abrasive, for example,
JP 49-91994, JP 49-94712, JP 50-64198, JP 50-65497, JP 51-928695, JP 51-136841 , and those described in Japanese Patent Publication No. 54-4919 are used. To give a more specific example:
Sold under the Zeodent, Zeo, and Sident trademarks with primary particles of 500 mμ or less and secondary particles of 1 to 30
μ precipitated silica, silica xerogel, silica aerogel, etc. can be used. In this case, precipitated silica is particularly preferably used, with a SiO ₂ content of 70% or more, preferably 90% or more, an alkali/alkaline earth metal oxide content of 0 to 5%, and a content of aluminum, magnesium, calcium, etc. relative to SiO ₂ . The amount of metal oxide bonding is 0 to 10%, preferably 0 to 5%,
Adhesive moisture content (loss on drying) of 1 to 10%, average particle size of 0.5 to 30μ, more preferably 1 to 15μ, 1
Specific surface area per g (BET method) ^500m2 or less, more preferably ^300m2 or less, refractive index 1.44-1.47, liquid absorption amount
Those having properties of 0.6 to 1.3 cc/g are preferably used. Specifically, Zeo49 from Huber in the United States,
Zeodent113, Syloid AL− from WRGrace, USA
1, 63, 74, 404, J.Crossfield & Sons Ltd., UK.
Examples include Neosyl ET, Sident 3 and 20 from Degussa, Germany. In the present invention, these silica-based abrasives are effectively used. In addition, examples of the thickening agent include sorbitol, glycerin, ethylene glycol, propylene glycol, 1,3-butylene glycol, polyethylene glycol, polypropylene glycol, xylitol, maltit, lactitt, etc., and one or more of these can be used. Can be blended (compounding amount usually 10-75%). Furthermore, in the dentifrice composition of the present invention, water-soluble salts of higher alkyl sulfates whose alkyl group has 8 to 18 carbon atoms, such as sodium lauryl sulfate and sodium myristyl sulfate, sodium hydrogenated coconut oil fatty acid monoglyceride monosulfate, etc. Water-soluble higher fatty acid monoglyceride monosulfate, alkylaryl sulfonate such as sodium dodecylbenzenesulfonate, higher alkyl sulfonate,
substantially saturated lower aliphatic aminocarboxylic acid compounds such as higher fatty acid esters of 1,2-dihydroxypropanesulfonate, sodium, potassium or ethanolamine salts of N-lauroyl, N-myristoyl or N-palmitoylsarcosine; anionic activators such as higher aliphatic acylamides;
Sucrose fatty acid esters with a fatty acid group having 12 to 18 carbon atoms such as sucrose mono- and dilaurate, lactose fatty acid ester, lactitol fatty acid ester, maltitol fatty acid ester, stearic acid monoglyceride, polyoxyethylene sorbitan monolaurate, polyoxy Ethylene Sorbitan Monostearate, Polyoxyethylene (10,
(20, 40, 60, 80, 100 mol) hydrogenated castor oil, polymers of ethylene oxide and propylene oxide, and polyethylene oxide such as polyoxyethylene polyoxypropylene monolauryl ester, fatty acids, fatty alcohols, polyhydric alcohols, and polypropylene oxide. One or more surfactants (compounding amount usually 0 to 7%, preferably 0.5 to 5%), such as nonionic surfactants such as condensation products of
%), as well as saccharin sodium,
Sweeteners (0 to 1%, preferably 0 to 1%, preferably is 0.01~0.5%),
Furthermore, if necessary, p-hydroxymethylbenzoitsquaside, p-hydroxyethylbenzoitsquaside, p-hydroxypropylbenzoitsquaside, p-hydroxybutylbenzoitsquaside,
Preservatives such as sodium benzoate and lower fatty acid monoglycerides, fragrances such as wintergreen oil, spearmint oil, peppermint oil, satsafras oil, clove oil, and eucalyptus oil, gelatin, peptone, arginine hydrochloride, albumin, casein,
Brighteners such as titanium dioxide, silicones, pigments,
Other ingredients may be included. The dentifrice composition of the present invention also includes enzymes such as allantoin, epsilon aminocaproic acid, tranexamic acid, dextranase, amylase, protease, mutanase, lysozyme, lytic enzyme, and litetsuque enzyme, sodium monofluorophosphate, and monofluorophosphate. Alkali metal monofluorophosphates such as potassium fluorophosphate, fluorides such as sodium fluoride, ammonium fluoride, and stannous fluoride, chlorhexidine salts, dihydrocholesterol, glycyrrhetinic salts, glycyrrhetinic acid, glycerophosphate, chlorophyll, calopeptide , a water-soluble inorganic phosphoric acid compound, vitamins, an anti-tartar agent, an antibacterial agent, an anti-plaque agent, and the like may be combined with one or more active ingredients. The dentifrice composition according to the present invention uses igneous ultrafine amorphous silica and the appropriate ingredients mentioned above to have a viscosity of 200 to 600 poise, and has good extrudability. Moreover, despite its low viscosity, it has good shape retention and improved stringiness, so when you press a push button such as a push button, the contents are pressed and the contents are It can be used by being housed in a vertical pump type container that is pushed out from the outlet. In addition, as such pump-type containers, Utility Model Kai 54-34641, Utility Model Kai 55-38783, Utility Model Kai 56-
46572, Utility Model 56-100378, Utility Model 56-121677,
Utility model 57-44041, 74168 Utility model 57-7416, 1988 Utility model 57-
164079, JP-A-57-68367, JP-A-57-68368, etc., and the dentifrice composition of the present invention can be suitably used by filling these containers. Next, experimental examples will be shown to specifically explain the effects of the present invention. Experimental Example Toothpaste compositions having the formulations No. 1 to No. 7 shown in Table 1 were prepared. The igneous ultrafine amorphous silica used had an average primary particle diameter of 16 μm. Next, the viscosity of these toothpastes was measured using a BH type viscometer (at 25°C), and when these toothpastes were filled into a container described in Japanese Utility Model Publication No. 54-34641 and extruded from this container. The shape retention, stringiness, and ease of extrusion were evaluated. The results are shown in Table 2.

【table】

[Table] However, the evaluation criteria are as follows. Evaluation Criteria Shape Retention ○: Goes well on a toothbrush and does not lose its shape. △: The shape is slightly distorted. ×: Easier to wash than a toothbrush. Stringability ○: When placed on a toothbrush, there is no stringiness and the threading property is good. △: When placed on a toothbrush, stringiness is less than 5 cm. ×: When placed on a toothbrush, the stringiness is 5 cm or more. Ease of pushing out ○: Toothpaste comes out of the container without resistance. △: Some resistance is felt when pushing out from the container. ×: When extruding from the container, considerable resistance was felt and it was difficult to extrude. From the results in Table 2, the toothpaste composition containing igneous ultrafine amorphous silica has good shape retention despite its low viscosity, has good stringiness, and is easy to extrude from the container. It is found that Examples are shown below. Example 1 Precipitated silica 17% Propylene glycol 3 Glycerin 25 Sorbit 20 Gelatin 0.3 Sodium carboxymethyl cellulose 1 Pyrogenic ultrafine powder amorphous silica (average diameter of primary particles
16 μm) (Aerosil) 3 Sodium lauryl sulfate 1.5 N-lauroyl sarcosinate 0.3 Lauric acid diethanolamide 0.5 Sodium saccharin 0.1 Paraben 0.1 Fragrance 1 Purified water Balance 100.0% Viscosity 450 poise Example 2 Precipitated silica 17% Polyethylene Glycol 4 Glycerin 25 Sorbit 23 Gelatin 0.3 Sodium carboxymethylcellulose 0.5 Carrageenan 0.5 Igneous ultrafine amorphous silica (average diameter of primary particles 8 μm) (Aerosil) 2 Sodium lauryl sulfate 1.5 N-lauroyl sarcosinate 0.3 Lauric acid diethanolamide 0.5 Satucharin sodium 0.1 Paraben 0.1 Fragrance 1 Purified water Remaining amount 100.0% Viscosity 500 poise Example 3 Precipitated silica 15% Polyethylene glycol 4 Glycerin 20 Sorbit 22 Gelatin 0.5 Igneous ultrafine amorphous silica (average of primary particles) The diameter is
16 μm) (Aerosil) 3 Sodium lauryl sulfate 1.5 N-lauroyl sarcosinate 0.3 Lauric acid diethanolamide 0.5 Satucalin sodium 0.1 Chlorhexidine hydrochloride 0.01 Paraben 0.1 Fragrance 1 Purified water Remaining total 100.0% Viscosity 530 poise Example 4 2nd Calcium phosphate 30% Polyethylene glycol 3 Sorbit 35 Sodium carboxymethyl cellulose 1.2 Igneous ultrafine amorphous silica (average diameter of primary particles 8 μm) (Aerosil) 2 Sodium lauryl sulfate 1.8 Sodium saccharin 0.1 Sodium monofluorophosphate 0.76 Paraben 0.1 Fragrance Materials 1 Purified water Balance 100.0% Viscosity 600 poise Example 5 Calcium carbonate 25% Propylene glycol 2.5 Glycerin 25 Sorbit 10 Sodium carboxymethyl cellulose 0.9 Pyrogenic ultrafine amorphous silica (average diameter of primary particles is 8 μm) (Aerosil) 3 Sodium lauryl sulfate 1.5 Sodium saccharin 0.1 Chlorhexidine hydrochloride 0.01 Paraben 0.1 Fragrance 1 Purified water Balance 100.0% Viscosity 580 poise Example 6 Aluminum hydroxide 35% Propylene glycol 3 Sorbit 30 Gelatin 0.5 Sodium alginate 1 Super igneous Fine powder amorphous silica (average diameter of primary particles is 8 μm) (Aerosil) 2 Sodium lauryl sulfate 1.2 Lauric acid diethanolamide 0.5 Sodium saccharin 0.1 Sodium monofluorophosphate 0.76 Dextranase 2000u/g Paraben 0.1 Fragrance 1 Purified water Remaining Total 100.0% Viscosity 590 poise Example 7 Insoluble sodium metaphosphate 35% Propylene glycol 3 Glycerin 25 Sorbit 23 Sodium carboxymethyl cellulose 1 Pyrogenic ultrafine powder amorphous silica (average diameter of primary particles
16 μm) (Aerosil) 3 Sodium lauryl sulfate 1.5 N-lauroyl sarcosinate 0.3 Sodium saccharin 0.1 Chlorhexidine hydrochloride 0.01 Paraben 0.1 Fragrance 1 Purified water Balance 100.0% Viscosity 550 poise Example 8 Precipitated silica 10% Propylene glycol 3 Glycerin 20 Sorbit 10 Gelatin 0.5 Carrageenan 1 Igneous ultrafine powder amorphous silica (the average diameter of the primary particles is
40μm) (Aerosil) 4 Sodium lauryl sulfate 1.5 Lauric acid diethanolamide 0.5 Sodium saccharin 0.1 Tranexamic acid 0.01 Paraben 0.1 Fragrance 1 Purified water Remaining amount 100.0% Viscosity 320 poise All of the toothpastes of Examples 1 to 8 were It has good formability, stringability, and ease of extrusion, and is
Even when it was housed in the container described in Publication No. 54-34641, it was possible to extrude it smoothly.

Claims (1)

[Claims] 1. Igneous ultrafine amorphous silica whose primary particles have an average diameter of 5 to 50 μm is 1 to 5% by weight of the entire composition.
A dentifrice composition characterized in that it is formulated with a viscosity of 200 to 600 poise. 2. The dentifrice composition according to claim 1, which is housed in a vertical pump type container.