JPS6137168A - Body fluid treating circuit - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed Description of the Invention] (Industrial Application Field) The present invention relates to improvements in blood circuits and other circuits for treating body fluids, and in particular allows cleaning treatment before use to be routinely performed.
Moreover, it is an attempt to provide a circuit that can be operated hygienically.

(Prior art) Artificial kidneys, plasma separation devices, artificial livers, and other blood processing devices are connected to a body fluid introduction circuit and a body fluid discharge circuit, and body fluids such as blood taken from a patient are circulated through these circulatory system paths. It has been widely known to carry out purification treatment and the like.

In such a body fluid treatment system, it is necessary to wash the system with physiological saline or the like in order to remove dirt and air bubbles accumulated in the system before use.

A conventional example of this cleaning method will be explained with reference to FIG.

Figure 1O shows an example of an artificial kidney system composed of a dialer and a blood circuit connected to it, where l is a dialer filled with physiological saline, and 2 is a blood inlet of dialer 1. 4 is an arterial blood circuit connected to the blood outlet 5, and 3 is a venous blood circuit connected to the blood outlet 5.

A luer connector 6.7 as shown in FIG. 11 is connected to the tips of these circuits 2.3, and a cap 8 is attached to this luer connector 6.7 via a body 8a. and the cap 8 are connected by a connecting band 9.

When cleaning such a body fluid circulation circuit system, a physiological saline filling tube is connected to the Luer connector 6 for shunt connection attached to the distal end of the arterial blood circuit 2, and physiological saline is injected through the tube. Usually, the liquid is introduced into the blood circuit 2, passed through the dialyzer 1 and the venous blood circuit 3, and then discharged from the Luer connector 7 of the circuit 3.

(Problems to be Solved by the Invention) However, according to the conventional method as described above, the filled physiological saline solution is discharged after passing through the system once, so a large amount of physiological saline solution is discharged. This method requires saline solution, which is not only wasteful, but also has drawbacks such as the fact that small dust and air bubbles stuck in the system cannot be completely removed, and the operation is troublesome.

Further, since the cap parts 8 and 9 have a complicated structure and are manufactured by injection molding, it is difficult to mass-produce them and the production cost is high.

(Means for Solving the Problems) In order to solve the above-mentioned conventional drawbacks, the present invention
By attaching a chip to the junction connection part of the body fluid inlet side circuit and/or the body fluid outlet side circuit and connecting both shunt connection parts via the chip, a sealed circuit is formed, and this circuit is filled in advance. This is to circulate the filled filling liquid.

Furthermore, a chip is attached to the shunt connection portions, and these shunt connection portions are connected with a breathable connector, and sterilization is performed in this state.

Furthermore, a filter with a bore size of 2007L or less is provided in a location other than the trip chamber in the circuit to efficiently remove minute dust.

(Example) Embodiments of the present invention will be described below with reference to the accompanying drawings.

FIG. 1 shows an example in which the present invention is applied to an artificial kidney device, in which IO is a dialer whose interior is filled with physiological saline, and 12 is connected to the blood supply 14 of the dialer 10. Arterial blood circuit, 13 is blood outlet 15
The venous blood circuit is connected to the venous blood circuit, which is the same as the conventional one.

In this embodiment, a shunt connection part 16.17 is attached to the distal end of each blood circuit 12.13, and a chip 1 as shown in FIG. 2 is attached to each shunt connection part 16.17.
8.19 is removably attached.

The tips of these tips 18 and 19 are tapered and sharp, and the inner diameter of the tips is the same as that of the shunt connection portion 16.
．． The diameter is large enough to fit the tip of No. 17, and the outer diameter is large enough to fit into the infusion port of an infusion bag, which will be described later.

FIG. 3 shows an embodiment convenient for sterilizing the blood circuit 12, 13 described above, in which each shunt connection 16, 17 is inserted into the connector 26, facing each other. As shown in FIG. 4, a plurality of protrusions 27 are formed inside the connector 26 at both ends, as shown in FIG. The sterilizing gas is allowed to enter through the gap 28 between the inner surface of the connector and the inner surface of the connector.

Such a connector 26 connects both shunt connections 16.
．． When EOG gas sterilization is performed after connecting 17, EOG gas enters through the gap 28 and circulates within each circuit. Tips 18.19 are provided in both shunt connections 16.17 for this purpose, but in some cases one of the tips may be omitted.
Furthermore, the configuration of the connector 26 is not limited to that shown in the drawings as long as it is breathable.

On the other hand, FIG. 8 shows another embodiment of the present invention, in which a filter 33 having a smaller bore size than the filter of the trip chamber 24 in FIG. 1 is provided inside the chip 18. The bore size of this filter is 200 mm or less.

When such a filter 33 is provided, foreign matter such as minute dust that cannot be removed by the filter of the trip chamber 24 adheres to and accumulates on the filter 33, thereby improving the efficiency of removing minute dust.

FIG. 8 and FIG. 9 show still another embodiment,
First, the tip 18a shown in FIG. 8 is such that both ends can be fitted into the inner surface of the shunt connection portion 16, 17, and a filter 33 is provided inside the center.

The tip 18b in FIG. 9 is a tip 18 with a sharp tip.
Instead, the shunt connection parts 16.17 can be inserted from both ends, and the stopper protrusions 34.34 are provided in the middle part.
, and a filter 33b is provided between these protrusions.

(Function) According to the present invention having the above configuration, first,
After connecting the arterial blood circuit 12 and the venous blood circuit 13 to the dialyzer 10 filled with physiological saline, the shunt connection part 17 of one blood circuit 12 is pulled out from the connector 26, and as shown in FIGS. As shown in a and b, this connector 26 is connected to an infusion bag 30 containing physiological saline.
The blood circuit 12 is inserted into the infusion port 31 of the infusion bar 7, and the tip 19 pierces the thin film 32 to communicate the blood circuit 12 with the infusion bar 7.

Next, after filling the circuit 12 with a predetermined amount of physiological saline in the infusion bag 30, the shunt connection part 17 is pulled out with the tip 19 remaining in the infusion port 31 as shown in FIG. 6C. , @continuation part is covered with the tip 19, so that a sterile state can be maintained even when physiological saline is introduced.

Next, the shunt connection part 16 of the other blood circuit 13 is pulled out from the connector 26, and the tip of the shunt connection part 17 is inserted into the tip 18 of this shunt connection part 16, as shown in FIG. 6d. It is. Thereby, the arterial side circuit 12 and the venous side circuit 13 are connected, and a sealed circuit as shown in FIG. 1 is formed.

After this, the liquid feeding pump 20 is driven to transfer the physiological saline in the system to the blood circuit 12. Dialyzer 510. The blood is circulated in the order of the blood circuit 13 to clean dirt adhering to the system, and while adjusting the liquid level in the trip chamber 24 through the monitor line 25, remove air bubbles slightly present in the system. , are concentrated in the trip chamber 24.

(Effects) According to the present invention described above, the shunt connection parts in the arterial and venous blood circuits are connected to form a closed system path, and the circulation cleaning within the system path can be repeatedly performed. The cleaning effect is 7-2 times higher than that of 1-pass cleaning.
The bubble removal effect is significantly improved, and waste of physiological saline can be prevented.

In addition, the physiological saline in the bag can be introduced into the circuit by simply inserting the shunt connection part into the infusion port of the infusion bag, which is easier to operate than before, and can be done under sterile conditions. It becomes possible to perform filling and washing operations with physiological saline.

Furthermore, it is possible to perform gas sterilization with the arterial and venous blood circuits connected using a connector, and this connector can be mass-produced at low cost by extrusion molding, so compared to conventional caps. Excellent effects such as a significant reduction in production costs can be obtained.

[Brief explanation of drawings]

FIG. 1 is an overall schematic diagram of a body fluid treatment circuit according to the present invention, FIG. 2 is a cross-sectional view of a shunt connecting portion according to the present invention, and FIG. 3 is a cross-sectional view of a shunt connecting portion showing another embodiment of the present invention. Figure 4 is a sectional view of the shunt connector of the present invention, Figure 5 is a state diagram when the shunt connector is inserted into an infusion bag, and Figures 6a to 6d are detailed explanations of the present invention. 7, 8, and 9 are all sectional views showing other embodiments of the present invention, FIG. 1θ is an overall schematic diagram of a conventional body fluid processing circuit, and FIG. FIG. 3 is a cross-sectional view of the shunt connection. In the figure, 10 is a dialer, 12 is an arterial blood circuit, 1
3 is the venous blood circuit, 16.17 is the shunt connection,
18 and 19 are chips, 26 are connectors, and 30 are infusion bags.

Claims (7)

[Claims] (1) A circuit for guiding body fluids out of the body, treating them, and then returning them to the body, where a chip is attached to the shunt connection of the body fluid introduction side circuit and/or the body fluid output side circuit, and both shunt connections are connected. A body fluid processing circuit characterized by being connectable. (2) A circuit for guiding body fluids out of the body, treating them, and then returning them to the body, where a chip is attached to the shunt connection of the body fluid introduction side circuit and/or the body fluid output side circuit, and both shunt connections are connected. A body fluid processing circuit characterized in that these shunt connection parts are connected by a breathable connector. (3) A circuit for guiding body fluids out of the body, treating them, and then returning them to the body, where a chip is attached to the shunt connection part of the body fluid introduction side circuit and/or the body fluid output side circuit, and both shunt connection parts are connected. In addition to making it possible to connect, there is a bore size of 200 mm in the circuit other than the trip chamber.
A body fluid processing circuit characterized by being provided with a filter of less than μ. (4) The invention according to item 1 or 2 above, wherein the tip end is formed sharply. (5) The invention described in item 1 or 2 above, wherein the chip is detachably attached to the shunt connection part. (6) The invention described in item 2 above, wherein a plurality of protrusions are formed on the inner surface of the connector. (7) The invention as described in item 3 above, characterized in that the filter is provided inside the chip.