JPS61272297A - Detergent composition - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a cleaning composition. More specifically, the present invention relates to a detergent composition that is less irritating to the skin and has excellent detergency and foaming power.

Although the detergent composition of the present invention can be used for a wide variety of purposes, it is particularly advantageous when used as a shampoo composition.

[Conventional technology]

Conventionally, cleaning compositions contain anionic surfactants such as alkyl sulfates and alpha olefin sulfonates, nonionic surfactants such as fatty acid alkylolamides, and zwitterions such as alkyl betaines and alkyl amine oxides. Surfactants have been used.

[Problem that the invention seeks to solve]

When using these surfactants alone, although anionic surfactants have excellent cleaning and foaming power, they are all highly irritating to the skin, and nonionic surfactants are highly irritating to the skin. In the case of surfactants and amphoteric ionic surfactants, they are less irritating to the skin, but their cleaning power and foaming power are insufficient for dirt with heavy oil stains.

The present inventors focused on the above points and, as a result of intensive research, found that surfactants and surfactant compositions with strong protein denaturing power are highly irritating to the skin, while surfactants with low protein denaturing power It has been found that the irritation to the skin is significantly reduced in the surfactant composition.

Furthermore, it has been shown that if a specific anionic surfactant and a specific nonionic surfactant are combined, the protein denaturation rate will be synergistically reduced and skin irritation will be significantly reduced compared to when each agent is used alone. I found it. The present invention is based on this knowledge.

[Means for solving problems]

That is, the present invention provides a compound represented by the general formula (A) RCOOCH2CH2SO3M (A) (wherein R represents an alkyl group or alkenyl group having an average number of carbon atoms of 7 to 19, and M represents an alkali metal or an organic amine). The present invention provides a cleaning composition characterized by containing an isethionate-type anionic surfactant having an HLB of 10 to 16 and a nonionic surfactant having an HLB of 10 to 16.

A particularly preferable blending ratio of the active ingredients is the isethionate-type anionic surfactant represented by the general formula (A) and the HLB
The weight ratio of 9 to the nonionic surfactant having a ratio of 10 to 16 is in the range of 1 to 2:3, and the total of the two accounts for about 10 to 50 parts by weight of the total.

The present inventors have found that when an isethionate-type surfactant represented by the general formula (A) and a nonionic surfactant with an HLB of 10 to 16 are mixed at an appropriate mixing ratio, foaming properties, cleaning properties, etc. The surfactant ability of is not inferior to that of the anionic surfactant represented by the general formula (A) alone,
At the same time, it was discovered that protein denaturation power, ie, skin irritation, was significantly reduced to an extent that was at least as good as that of a nonionic surfactant alone. The phenomenon of this synergistic effect was considered to be due to the formation of mixed micelles based on measurements of critical micelle concentration, etc. If the nonionic surfactant used has an HLB of less than 10, the protein denaturation power will decrease, but perhaps because the HLB is low, the nonionic surfactant will act like an oil, resulting in foaming and foaming properties.
Cleanability is significantly poor.

Furthermore, when a nonionic surfactant with an HLB of 16 or more is used, the protein denaturation performance does not decrease much and the foaming property is also poor. As mentioned above, the HLB of the nonionic surfactant is preferably 10 to 16, but the preferred HLB is 11 to 14, which is particularly effective.

The isethionate-type anionic surfactant represented by the general formula (A) used in the present invention has, for example, C1□H23COO-1C13 as the fatty acid group RCOO-.
H27COO-1C15H31COo-1C17H2S
Examples of the counter ion M include Coo-1C17H33CoO-, coconut oil fatty acid, and the like, -Li, -K, Nas monoethanolamine, jetanolamine, triethanolamine, and the like.

The nonionic surfactant used in the present invention is HLB
A nonionic surfactant having IO to 16, preferably 11 to 14, polyoxyethylene alkyl ether type, polyoxyethylene alkylphenyl ester type, polyoxyethylene polyoxypropylene alkyl ester type, polyoxyethylene polyhydric alcohol fatty acid. Examples include ester type, polyglycerin fatty acid ester type, and polyoxyethylenated castor oil type. A particularly preferred nonionic surfactant in the present invention is a polyoxyethylene alkyl ether type.

In addition, HLB is the hydrophilic-lipophilic balance (Hydr
ophilic-Lypophilic Balanc
e), and in the present invention, the value calculated using the formula by Koide and Teramura et al. is used.

In addition to the above-mentioned essential components, the cleaning composition of the present invention can contain components of known cleaning compositions.

For example, amphoteric surfactants, cationic surfactants, higher alcohols, lanolin derivatives, protein derivatives, oily components such as fatty acid esters of polyethylene glycol, propylene glycol, glycerin, polyethylene glycol in amounts that do not impair the effects of the present invention. Moisturizer ingredients such as herbal medicines, plant extracts such as herbal medicines, water-soluble polymer substances such as cationic, anionic, and nonionic, sequestrants, preservatives, bactericidal PHfJ [preservatives, ultraviolet absorbers, oxidants] Inhibitors, dyes, fragrances, etc. can be added as necessary.

In particular, cationic polymeric substances that are blended in shampoo compositions for the purpose of improving usability, such as cationically modified cellulose ether derivatives (Polymer JR (U, C, C"
), polyvinylpyrrolidone derivative quaternary ammonium (GAF, etc.), diallyldimethylammonium chloride polymer (Merk, etc.), polyacrylic acid derivative quaternary ammonium (Cart, etc.)
EX (NationalStarch, etc.), polyamide derivative quaternary ammonium (5andoz, etc.) increases the amount of adsorption to the hair by blending it into the cleansing composition of the present invention, and has greater usability than when blended with other bases. You can make improvements.

〔Effect of the invention〕

The present invention will be specifically explained below using experimental examples.

The test methods considered in the experimental examples are as follows.

Foaming test method CaCO370P In artificial hard water, a sample concentration of 1% solution was
The amount of foaming was measured using a cylindrical cylinder equipped with a stirrer at a temperature of 40°C.

O...Good foaming, foam volume 2000ml! More than △・
...Normal foaming Foam amount 1500- or more, less than 2000-×...poor foaming Foam amount less than 1500-Cleanability test method CaO/MgO=3/1.5°DH Artificial hard water, sample concentration 1% solution and washed artificial sebum-contaminated cloth using wool surge.

Turbotometer (JISK-3
371) was used to determine the cleaning efficiency from the reflectance before and after cleaning.

Ro: Reflectance of original fabric (wool serge) R3: Reflectance of contaminated cloth RW: Reflectance of contaminated cloth after washing ○... Good cleaning performance Cleaning efficiency 80% or more △... Fair cleaning performance Cleaning efficiency 60 % or more but less than 80% ×...
Poor cleaning performance Washing efficiency Less than 60% Protein denaturation rate measurement method Using aqueous high performance liquid chromatography, when a sample is added to an egg albumin pH 7 buffer solution at a sample concentration of 1%, the ovalbumin denaturation rate is 220n
It was measured using the m absorption peak.

SaH5: 220 when the sample was added to the ovalbumin buffer
Height of nm absorption peak ◎... Ovalbumin denaturation rate less than 30% O... Ovalbumin denaturation rate 30% or more but less than 60% △...
Ovalbumin degeneration rate: 60% or more, less than 80%×...
- Ovalbumin denaturation rate 80% or more (blank below) Skin irritation test method Prepare a 10% sample concentration solution with ion-exchanged water, immerse the guinea pig in this test solution for 4 hours every day, and repeat this for 3 days. After 12 hours of immersion, the appearance of a reaction was observed for 2 days. The reaction was evaluated using five criteria: erythema, edema, relaxation, desquamation, and fissures.

■... is hardly stimulating.

(Erythema appears.) ○... Mild irritation (erythema and relaxation appear.) ×... Severe irritation (erythema, edema, relaxation, and desquamation appear.) ×... Extremely Severe irritation (produced erythema, edema, relaxation, desquamation, and cracks) Experimental example 1 A shampoo with the composition shown in Table 1 below was prepared, and its foaming properties, detergent properties, and protein denaturation were evaluated. The rate and skin irritation were investigated.

Experimental Example 2 A shampoo having the formulation shown in Table 2 below was prepared, and its foaming properties, cleansing properties, protein denaturation rate, and skin irritation were examined.

(Margin below)

Claims (1)

[Claims] General formula (A) RCOOCH_2CH_2SO_3M (A) (in the formula R
represents an alkyl group or alkenyl group having an average carbon number of 7 to 19, and M represents an alkali metal or an organic amine. 1. A cleaning composition comprising an isethionate-type anionic surfactant represented by the following formula and a nonionic surfactant having an HLB of 10 to 16.