JPS60224612A - Composition for oral cavity - Google Patents

Abstract

PURPOSE:A composition useful as toothpaste, filler kiss paste, etc. having proper polishing properties by itself, showing improved luster imparting effect on the teeth, having proper polishing power, cleaning power, obtained by blending an oral cavity composition with anhydrous alpha-alumina having a specific crystal size. CONSTITUTION:An oral cavity composition is blended with alpha-alumina anhydride having 0.1-2.5mum average crystal size. alpha-Alumina comprising particles having 0.1-4.5mum secondary aggregation particle diameters, containing no particles having >=5mum secondary aggregation particle diameter, is preferably used as the alpha-alumina anhydride. The composition for oral cavity obtained reduces surely scratch, has no feeling of roughness to the tongue, and has good feeling in use. An amount of alpha-alumina anhydride blended is 0.1-60wt% based on total amount of the composition, and especially 0.1-10wt% when it is mixed with another polishing material. EFFECT:Even if the alpha-alumina anhydride is mixed with a polishing agent having high polishing power such as Al(OH)3, calcium hydrogenphosphate containing no hydrate, polishing silica, etc., it can make the teeth smooth without damaging them.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to oral compositions such as toothpaste and Glophyllakis yeast, and more specifically relates to oral compositions capable of imparting gloss to tooth surfaces.

In general, oral compositions such as toothpaste and glophilakis paste have a high ability to efficiently remove stains, graffiti food particles, and other substances that have adhered to or deposited on teeth by physical action, and have excellent cleaning ability. What is desired is desired.

In this case, the efficiency of physical removal of food particles, etc. can be increased by increasing the abrasive power of the abrasive, and the cleaning effect on the tooth surface can be improved, but increasing the abrasive power It scrapes the tooth surface, making it easier to damage.
This may reduce the gloss of the tooth surface.

For this reason, brighteners are used in combination with abrasives to give gloss to the tooth surface, smooth it, and prevent plaque and tartar from accumulating. Although it is effective when used alone or in combination with abrasives with little abrasiveness, highly abrasive abrasives such as aluminum hydroxide, calcium hydrogen phosphate anhydrate, abrasive silica, carbonic acid In combination with calcium, etc., no gloss improvement effect could be obtained.

The present inventors have found that the polishing power is moderate, the cleaning power is good, and it is possible to give gloss to the tooth surface.It can be used as an abrasive by itself, and it can also be used in combination with an abrasive with high abrasive power. We conducted extensive research into a base material that can improve the gloss of the tooth surface without damaging the tooth surface, and can therefore be effectively used as a brightener.As a result, we found that the average crystal size was 0.1.
α-Alumina anhydride (α-A/1.
It has been found that the above object can be effectively achieved by using 203).

That is, the above object can only be effectively achieved when using α-alumina anhydride having the above-mentioned specific crystal size. By blending α-alumina anhydride with a diameter of 2.5 μm, it has a high gloss imparting effect on the tooth surface, and has appropriate abrasiveness itself. Even when used in combination with highly abrasive abrasives such as calcium oxyhydrogen anhydrate, abrasive silica, and calcium carbonate, the tooth surface can be smoothed without damaging the tooth surface, resulting in a good gloss on the tooth surface. found that it is possible to obtain an oral composition that can impart
This is what led to the present invention.

The present invention will be explained in more detail below.

The oral composition according to the present invention has an average crystal size of 0.
．． α-alumina anhydride (α-μ20
3), and by using this type of α-alumina anhydride, excellent gloss can be imparted to tooth surfaces.

On the other hand, the average crystal size is 0.1 μmJ:l
) Small ones and those larger than 2.5 μm do not have a sufficient gloss imparting effect, and especially when combined with a highly abrasive abrasive, they do not have a gloss imparting effect on the tooth surface.

In addition, it is preferable to use α-alumina anhydride that does not contain particles with a secondary agglomerated particle size of 5 μm or more, as this will reliably improve the gloss on the tooth surface and also reliably reduce scratches. A composition for the oral cavity that can be used in a variety of applications, has no rough texture, and has a good feeling of use can be obtained. On the other hand, if particles with a secondary agglomerated particle size of 5 μm or more are included, the gloss-enhancing effect is reduced, scratches are more likely to occur, a rough feeling is produced, and the usability may be deteriorated. Therefore, from this point of view, it is preferable that the average secondary agglomerated particle diameter of the α-alumina anhydride is 0.1 to 4.5. If it is smaller than 0.1 μm, a sufficient gloss improvement effect cannot be expected, and if it exceeds 4.5 μm, the proportion of particles having a secondary agglomerated particle diameter of 5 μm or more is usually high.

The amount of α-alumina anhydride used in the present invention is appropriately selected depending on the type of oral composition, purpose of use, etc., and is not particularly limited, but is usually 0.1 to 60% by weight of the entire composition, especially other It is preferable that the amount is 0.1 to 10% by weight when used in combination with a polishing substrate, and 5 to 50% by weight when the α-alumina anhydride according to the present invention is used alone.

In this case, the alumina anhydride of the present invention can be used alone as an abrasive, or can be used in combination with other abrasives as an abrasive or brightener. As other abrasives used in combination with the alumina anhydride of the present invention, known abrasives can be used, with particular limitations including:
Calcium hydrogen phosphate, anhydrous, material, abrasive silica, calcium carbonate.

Highly abrasive abrasives such as aluminum hydroxide can be effectively used in combination, and in the present invention, even when this type of abrasives with high abrasive power is used, the tooth surface will not be damaged and excellent gloss will be imparted. be able to.

In addition, in the present invention, the total amount of abrasive is 5 to 951
% is preferably 5 to 60%.

The oral composition according to the present invention can be used as a toothpaste or toothpaste.

It can be prepared as a dentifrice such as a moisturized toothpaste, a glofilakis paste, etc., and as other components of the oral composition of the present invention, appropriate components depending on the type thereof can be used.

For example, in the case of toothpaste, Cal is sodium oxymethylcellulose, hydroxyethylcellulose, alginate, caradanan, gum arabic, a binder such as lipinyl alcohol, polyethylene glycol, sorbitol, and glycerin.

Thickening agents such as propylene glycol, sodium lauryl sulfate, sodium dobuflubenzenesulfone, sodium hydrogenated coconut fatty acid monoglyceride monosulfate, sodium lauryl sulfoacetate, sodium N-lauroyl sarcosinate.

Foaming agents such as N-acylglutamate, lauroylgetanolamide, and sucrose fatty acid ester.

In addition, essential oils such as peppermint and solacemint, fragrance materials such as t-menthol, calgen, eugenol, and anethole, saccharin sodium, stevioside, neohes 4 lysyl dihydrochalcone, glycyrrhizin, perillartin, p-methoxycinnamic qualdehyde, and thaumatin. Sweeteners and preservatives such as lysozyme chloride, dextranase, lytic enzymes, mutanase, chlorhexidine or its salts, sorbic acid, alexidine,
Hinokitiol, cetylpyridinium chloride, alkylglycine, alkyldiaminoethylglycine salt, allantoin, C-7 minocazolone, tranexamic acid,
Azulene, vitamin E.

Active ingredients such as sodium monofluorophosphate, sodium chloride, fluoride, stannous chloride, water-soluble primary or secondary phosphates, quaternary ammonium compounds, and sodium chloride may be incorporated.

Hereinafter, the effects of the present invention will be specifically explained with reference to experimental examples. In addition, in the following examples, all numbers in the compounding amount indicate weight %.

[Experimental Example 1] A toothpaste having the following formulation was produced using α-alumina anhydride having the crystal size shown in Table 1.

The α-alumina used was one that did not substantially contain particles having a secondary agglomerated particle size of 5 μm or more.

Toothpaste formulation α-alumina anhydride 1.0 Calcium hydrogen phosphate, dihydrate 20.0 Calcium hydrogen phosphate, anhydrate 20.0 Colloidal silica 2
．． 0 Propylene glycol 2.0 Sorbitol 20.0 Sodium carboxymethyl cellulose 1.0 Sodium lauryl sulfate 1.5 Sodium saccharin 0.1 Fragrance 1.0 Preservative Trace amount 100, Ots Size of α-alumina crystals was measured using an electron microscope). In addition, α-alumina was produced by the anhydrous Habayer method, and by controlling the manufacturing conditions, α-alumina having a crystal size of 0.1 to 20 μm could be obtained. The gloss improvement effect of toothpaste was investigated using the following method.

Gloss improvement measurement method A raw tooth cut to the size of 5 x 5 cod was embedded in resin, the surface of Chitose enamel was smoothed with a rotary polisher, and then polished to a 120 mm
0 emery paper polishing, polishing with calcium hydrogen phosphate anhydrate, puff polishing with a gloss meter (Nippon Denshoku Kogyo Co., Ltd. G)
LO8S METERVG-ID) +7) The enamel surface was treated to a gloss level of 80.0±2.0.

Next, add 10.9 parts of the sample toothpaste to 40 parts of the trisolbit solution.
017 was injected into the polishing container in which the natural tooth was set, and brushed with a horizontal polishing tester at a load of 200F and 7000 strokes/40 minutes, and then tested with a gloss meter. The increase and decrease in glossiness was measured, and the difference from the initial glossiness was defined as the degree of gloss improvement.

In this case, the level at which glossiness is recognized as being sufficiently glossy by visual inspection is +20 or higher in terms of gloss improvement, and the level at which ripples are recognized as glossiness is +15 or higher.

In addition, as a brushing brush, the number of hair strands is 44,
A nylon (62) material with a bristles thickness of 8 mils (approximately 0.2 mm) and a bristles length of 12 m was used, and the hardness of the material was MO according to the Household Goods Quality Indication Law.

The results are shown in Table 1.

Table 1 According to the results in Table 1, α-alumina anhydride with an average crystal size of 3 or more has no gloss imparting effect on the tooth surface; When a small α-alumina anhydride is used, it is recognized that excellent gloss is imparted to the tooth surface even when calcium hydrogen phosphate anhydrate, which has a relatively high abrasive power, is used as the abrasive.

[Experimental Example 2] A toothpaste having the same formulation as Experimental Example 1 was produced using α-alumina anhydride shown in Table 2.

α-alumina crystals having a size of 0.9 μm were processed under different grinding conditions to prepare α-alumina anhydride having various particle size distributions shown in Table 2.

Next, Experimental Example 1 in which these α-alumina anhydrides were blended
Toothpastes with the same formulation were manufactured, and the gloss improvement, scratch resistance, and feel (roughness) of these toothpastes were examined using the following method.The method for measuring the gloss improvement was as described in Experimental Example 1.
〇Measurement method for scratch (RfllI!) One of the methods to express scratch surface roughness Maxlmum height, Rma3C
) was evaluated by measuring. Here, the maximum height (Rmax) is defined as the vertical magnification of the cross-sectional curve when the sampled part is sandwiched between two straight lines parallel to the average line of the standard length of the cross-sectional curve. The value is expressed in μm when measured in the direction of .

Note that the cross-sectional curve was measured using a universal surface profile measuring instrument SE-3C (manufactured by Koita Institute).

Roughness was evaluated using the paired comparison method of 5choff2.

Evaluation Criteria Toothpaste A has a little more roughness than toothpaste B -2 Slightly less roughness -1 No difference 0 Slightly more roughness I I More roughness 2 Here, the lower the score, the less roughness. show.

According to the results in Table 2, even if α-alumina anhydride has an average crystal size of 2.5 or less, the gloss will improve if it contains secondary agglomerated particles with a particle size of 5 μm or more. 6. Not only does it reduce the strength of the product, it also causes scratches on fine surfaces and gives a rough feel. Ta. On the other hand, when α-alumina anhydride that does not contain secondary agglomerated particles with a diameter of 5 μm or more is used, it imparts superior gloss to the tooth surface and is free from grains that cause scratches on the tooth surface. less,
It was also found that the graininess was less.90 [Experimental Example 3] In the formulation shown in Experimental Example Process, the amount of α-alumina anhydride was varied within the range of 0 to 10 degrees. A toothpaste was manufactured and its gloss improvement degree was evaluated and used.

Table 3 According to the results in Table 3, α-alumina anhydride was added to 0.1 of the total.
It is recognized that excellent gloss can be imparted to the tooth surface by adding more than 10% of the total amount by weight.

Examples are shown below. Note that the gloss improvement degrees shown in the following examples are all values measured by the same method as above. In addition, in the following examples, the α-alumina anhydride used was one that did not actually have a secondary agglomerated particle size of 5 or more.

[Example 1] α-Alumina anhydride 1.0% Aluminum hydroxide 40.0 Colloidal silica 2.0 Propylene glycol 2.0 Glycerin 25.0 Cal? Sodium oxymethylcellulose 1.0 Sodium lauryl sulfate 1.5 Sodium saccharin 0.1 Fragrance 1.0 Preservative Microneedle 100.0% Gloss improvement 20.8 [Example 2] α-Alumina anhydride 2.0 Chirin Calcium dihydrogen dihydrate 20.0 Calcium dihydrogen phosphorus anhydrate 20.0 Colloidal silica 2
．． 0 Propylene glycol 2.0 Soyapitol 10.0 Glycerin 10.0 Sodium Calgaxymethylcellulose 0.8 Carrageenan 0.3 Sodium lauryl sulfate 1.5 Sodium quince o, i Fragrance 1.0 Preservative Minor gloss improvement 23 .8 [Example 3] α-Alumina anhydride 1.0% Calcium carbonate 40.01 Colloidal silica 2.0 Propylene glycol 2.0 Sorbitol 20.0 Hydroxyethyl cellulose 1.2 Sodium lauryl sulfate 1.5 Karin Sodium 0.1 Flavoring 1.0 Preservative Microneedle 100. O% Gloss improvement 21.2 [Example 4] α-Alumina anhydride 10.0% Amorphous precipitated silica 25.0 Colloidal silica 2.0 Propylene glycol 2.0 Sorbitol 20.0 Cal? Sodium oxymethylcellulose 1.0 Sodium lauryl sulfur 1.5 Sodium saccharin 0.1 Fragrance 1.0 Preservative Trace amount of water Residual gloss improvement 20.6 [Example 5] α-Alumina anhydride 45.0 Thipropylene glycol 2.0 Sorbitol 10.0 Glycerin 10.0 Sodium calgeximethylcellulose 1.0 Sodium lauryl sulfate 1.5 Satsukari/sodium 0.1 Fragrance 1.0 Preservative Microneedle i o o, ochi Gloss improvement degree 20. 5

Claims (1)

[Scope of Claims] 1. An oral composition comprising α-alumina anhydride having an average crystal size of 0.1 to 2.5 μm. 2. α-Alumina anhydride is substantially JC5JtmC2O
The oral composition according to claim 1, which does not contain quaternary agglomerated particles. 3. The amount of α-alumina anhydride is 0.1 to 6 of the total content.
The oral composition according to claim 1 or 2, which contains 0% by weight. 4. The oral cavity according to any one of claims 1 to 3, which contains as an abrasive one or more selected from aluminum hydroxide, calcium hydrogen phosphate anhydrate, abrasive silica, and calcium carbonate. Composition.