JPS6490184A - Pyridonecarboxylic acids - Google Patents
Pyridonecarboxylic acidsInfo
- Publication number
- JPS6490184A JPS6490184A JP62247350A JP24735087A JPS6490184A JP S6490184 A JPS6490184 A JP S6490184A JP 62247350 A JP62247350 A JP 62247350A JP 24735087 A JP24735087 A JP 24735087A JP S6490184 A JPS6490184 A JP S6490184A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- expressed
- lower alkyl
- compound expressed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000007513 acids Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- -1 (substituted)phenyl Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910015900 BF3 Inorganic materials 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical group C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- WTEOIRVLGSZEPR-UHFFFAOYSA-N boron trifluoride Chemical compound FB(F)F WTEOIRVLGSZEPR-UHFFFAOYSA-N 0.000 abstract 1
- 239000013522 chelant Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
NEW MATERIAL:A compound (salt or ester) expressed by formula I [R<1> represents cycloalkyl, (substituted)phenyl, etc.; W represents formula II (R<2> represents H, lower alkyl, etc.), N, etc.; Z represents formula III (R<4>-R<6> repre sent H, lower alkyl, etc.; A represents ethylene, etc.; m is 1 or 2), etc.]. EXAMPLE:1-Cyclopropyl-6-fluoro-7-(4-sulfomethyl-1-piperazinyl)-1,4-dih ydro-4-oxo quinoline-3-carboxylic acid. USE:A remedy for microbism. PREPARATION:For example, borofluoric acid is added to a compound expressed by formula IV (R<9> represents H, methyl, etc.; Hal represents halogen atom) to form a boron fluoride chelate compound, which is then reacted with an amine compound expressed by the formula H-Z'Q (Z' represents the same as Z; Q represents alkali metal) in a solvent in the presence of a deacidifying agent to afford the compound expressed by formula I.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62247350A JPS6490184A (en) | 1987-09-30 | 1987-09-30 | Pyridonecarboxylic acids |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62247350A JPS6490184A (en) | 1987-09-30 | 1987-09-30 | Pyridonecarboxylic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6490184A true JPS6490184A (en) | 1989-04-06 |
Family
ID=17162104
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62247350A Pending JPS6490184A (en) | 1987-09-30 | 1987-09-30 | Pyridonecarboxylic acids |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6490184A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993015070A1 (en) * | 1992-01-31 | 1993-08-05 | Chugai Seiyaku Kabushiki Kaisha | Crystal of quinolonecarboxylic acid derivative hydrate |
US7902227B2 (en) * | 2007-07-27 | 2011-03-08 | Janssen Pharmaceutica Nv. | C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents |
CN102295652A (en) * | 2011-06-27 | 2011-12-28 | 辽宁海神联盛制药有限公司 | Improvement method for pazufloxacin mesylate synthesis process |
-
1987
- 1987-09-30 JP JP62247350A patent/JPS6490184A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993015070A1 (en) * | 1992-01-31 | 1993-08-05 | Chugai Seiyaku Kabushiki Kaisha | Crystal of quinolonecarboxylic acid derivative hydrate |
US5597923A (en) * | 1992-01-31 | 1997-01-28 | Chugai Seiyaku Kabushiki Kaisha | Quinolone carboxylic acid derivatives in crystalline hydrate form |
US7902227B2 (en) * | 2007-07-27 | 2011-03-08 | Janssen Pharmaceutica Nv. | C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents |
CN102295652A (en) * | 2011-06-27 | 2011-12-28 | 辽宁海神联盛制药有限公司 | Improvement method for pazufloxacin mesylate synthesis process |
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