JPS5889697A - Skin cleaner - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

Detailed Description of the Invention The present invention provides a high HLB nonionic surfactant with a hydrophilic lipophilic balance (HLB) value of 11 or more, and a low HLB nonionic interface with an HLB value of 10 or less that is liquid or paste-like at room temperature. The present invention relates to an N-acyl electric amino acid salt-based cream skin cleansing agent containing an active agent.

Conventionally, cream skin cleansers using N-acyl acidic amino acid salts have various pi(
Among them, the weakly acidic one is N
- Acyl acidic amino acid salts themselves are hypoallergenic, so they have been widely accepted by people with sensitive skin and people with alkaline hypersensitivity.

In this way, the N-acyl acidic amino acid base skin cleanser is
Although it has advantages in terms of ``skin safety'', it has problems in terms of material stability and appearance. That is, N
- In the case of acyl acidic amino acid salt-based cream-based detergents, unlike ordinary fat-based cream-based detergents, they harden especially at low temperatures, and crystals precipitate, resulting in deterioration in quality. It was difficult to obtain a creamy form with stability and appearance. Therefore, in order to solve such problems, conventionally, certain types of additives have been used. For example, using fatty acid jetanolamide, surfactants, etc.
-Efforts have been made to stabilize acyl acidic amino acid salts. However, these additives have relatively low skin safety, and irritation of the skin, which appears to be caused by the additives themselves, occurred in cleaning products containing them. For this reason, the inherent skin safety characteristics of N-acyl acidic amino acid salts have been diminished.

At present, our company has not found an N-acyl acidic amino acid salt-based cream skin cleansing agent on the market that satisfies both stability and skin safety, and there has been a need to develop a cleansing rate.

As a result of research conducted in view of the current situation, the present inventors found that when a high HLB nonionic surfactant is combined with a low HLB nonionic surfactant that is liquid or paste-like at room temperature, stability is improved. The present invention has been completed by providing a creamy skin cleansing agent based on N-acyl acidic amino acid salts that has a good appearance and is safe for the skin.

That is, the present invention is a creamy skin cleanser containing an N-acyl acidic amino acid salt, a high HLB nonionic surfactant with an HLB value of 11 or more, and a low HLB value of 10 or less that is liquid or paste-like at room temperature. HLB nonionic surfactant.

According to the present invention, an N-acyl acidic amino acid salt-based cream skin cleansing agent is provided which has excellent stability and appearance, and maintains skin safety.

The cleaning rate invention will now be described in detail.

The N-acyl acidic amino acid salt-based cream skin cleanser of the present invention is a combination of a nonionic surfactant with an HLB value of 1' cleansing rate and a nonionic surfactant in liquid or paste form at room temperature with an HLB value of 1O or less. It is characterized by points.

The N-acyl acidic amino acid salts used in the present invention are known as foaming detergents, and include monosodium N-lauroylglutamate, monoarginine N-myristoylglutamate, and monotriethanolamine N-balmitoyl aspartate.

Dipotassium N-stearoyl aspartate.

N-cocoylglutamate silydine and the like belong to this category.

The high HLB nonionic surfactant with an HLB value of 11 or more in the present invention contains fatty acids, fats and oils, higher alcohols, etc. in a high mole number such that the HLB value of the product is 11 or more, such as ethylene oxide H! ! It is a reaction product obtained by addition reaction with o) etc. If the number of moles of EO added is small, the HLB value will not exceed 11. For example, a hardened mustard oil BO adduct to which 25 moles or more of tf KO has been added has an HLB value of 1 or less in the case of a HO adduct.

Such high HLB nonionic surfactants include, for example, higher fatty acid EO adducts (12 to 22 carbon atoms, HLB value 1
2 or more), hydrogenated castor oil EO adduct (25 moles or more) (
(HLB 11 or more), higher alcohol EO adduct (carbon ly, 12-22.HLBi 12 or more), cholesterol KO adduct (HLB 11 or more), ethylene oxide propylene oxide copolymer (HLB & i z
etc.). One or more types of these can be blended.

These high HLB nonionic surfactants have mild effects on the skin and improve the stability of N-acyl acidic amino acidic detergents, helping to homogenize the product and prevent crystal formation. Hunger, also improves the appearance, increases gloss or smoothes the surface.

In the present invention, in order to provide even better low-temperature stability, the HLB value 10. The following low HLB nonionic surfactants are blended. Low HLB in liquid or paste form
Examples of nonionic surfactants include: Liquid glycerin fatty acid esters (HLB value 1O or less) such as glycerin isostearate, glycerin oleate, and glycerin laurate.

Liquid polyglycerol fatty acid esters such as diglyceryl diisostearate, triglyceryl trioleate, bentaglyceryl tetraoleate, pentaglyceryl tetralaurate (HLB value 10 or less)
, liquid fatty acid KO adducts such as isopalmitic acid ethylene oxide (KO) adduct, lauric acid EO adduct (HLB 10 or less), liquid higher alcohol such as oleyl alcohol EO adduct, instearyl alcohol EO adduct, etc. no adducts (HL B(l, 10 or less).

Liquid nlupitan fatty acid esters (HLB value 5 or less) such as sorbitan palmitoleic acid ester, flubitan laurate, and sorbitan isostearate, hydrogenated castor oil EO adduct (15 mol or less), coconut oil BO adduct, glycerol trichloride liquid or paste triglyceride KO adducts (HLBit
0 or less), dihydrocholesterol EO adduct (H
Liquid polyhydric alcohol fatty acid esters ((I, B candy 10 or less) such as sorbitol oleate, sucrose stearate, LB value 10 or less), sorbitol oleate, sucrose stearate, etc. be able to.

As mentioned above, low-HLB nonionic surfactants in liquid or paste form impart low-temperature stability to N-acyl acidic amino acid salt-based detergents, but as a result, the detergent cream does not harden at low temperatures. Especially when it comes to tube products, this problem does not occur because the cream is difficult to come out of the tube even at low temperatures. The content ratio of the high LB surfactant and the low HLB surfactant is 1:, 30-t 5 : 1°□, preferably 1:10 to s:1 (Ii).

In addition to the above-mentioned essential ingredients, the creamy skin cleansing agent of the present invention may normally contain other ingredients as desired. .

You can add other ingredients as appropriate. Other ingredients include 1. Moisturizing agents such as glycerin, sorbitol, maltitol, polyethylene glycol, propylene glycol, butylene glycol, fatty acids, higher alcohols, hydrocarbons, and fats and oils.

Superfatting agents such as lanolin and cholesterol 1. Additionally, glycyrrhizin, allantoin, and aloe powder.

Examples include drugs such as vitamins.

The content ratio of the cleaning agent of the present invention when these H-silver components are added is, for example, a foaming cleaning agent (H-acyl acidic amino acid salt).
10 to 60% by weight, nonionic surfactant total amount 1 to 10% by weight, humectant 5 to 60% by weight, superfat agent θ to 15% by weight.
1 purified water 15-70% by weight.

Examples of the present invention will be shown below. The scope of the present invention is not limited by the examples. In addition, in the examples, "%" indicates the weight of
5-(2) Glycerin 10% (3
) Polyethylene glycol 400 1
0% (4) Lauric acid 25% (5) Purified water 46.5% 94% After kneading in a beaker, the mixture was heated and dissolved to prepare a mixture (A) at 70°C.

Separately lower 1 pill (61+71 component 16) hydrogenated castor oil go adduct (60-vol) (tlLBk14.o)
3'% (7) Glyceryl dioleate CHLB value 1.2) 3% is placed in a beaker and heated to dissolve to form a mixture of 70"C (B)
made.

Mixture (B) was added to mixture (A), stirred at 70° C. for 10 minutes to evenly distribute the mixture, and then cooled to room temperature with stirring to obtain a creamy skin cleanser.

When a part of this cleaning agent was left in a constant temperature bath at 0° C. to examine its stability, it showed excellent low-temperature stability without precipitation of crystals.

As shown in Table 1 below, the resulting cleansing agent had a good appearance, moderate hardness even at low temperatures, and no problems with skin safety. On the other hand, in Table 1, Comparative Examples 1 to 3 (,
It does not contain either or both of an LB activator and a low HLB activator. ), no product showed good results in terms of appearance, &m, and skin safety.

No. 1ll (Note 1) Judgment is made by visually observing external appearance, crystal precipitation, etc.

O mark: good; The larger the number on the scale, the greater the hardness.

○ mark: Moderate △ mark: Slightly hard × mark: Hard (Note 3) Skin safety is determined by rabbit skin secondary irritation test at a concentration of 40%.

○ mark: JIIll no irritation, X mark: irritation Example 2~
6 Cleaning agents were prepared in the same manner as in Example 1 using the following formulations A-Fi. All cleaning products have a good appearance and are low temperature.
It also had moderate hardness and no problems with skin safety.0 [Formulation A] Monosodium N-lauroylglutamate 30
% polyoxyethylene cetyl ether (25 mol KO) (HL B Young 15.0)
3% diglyceryl diisostearate (HLB value 7.0) 3
Thimaltitol 10
% polyethylene glycol 400 20
% triethylene glycol distearate 1
% Glyceryl Monostearate (solid)
1% lauric acid
3% purified water 29% fragrance
Appropriate tone color
Appropriate amount [Formulation B] N-Lauroy asbadic acid monotriethanolamine 20% Lauric acid jetanolamide 3% ・Sorbitan triisostearate (HLB value 1.7) 0.
5% dihydrocholesterol EO adduct (40 mol) (HLB value 14.6)?
, 59! myristic acid
2. Coconut oil 1% Sodium pyrrolidone carboxylate 5. Polyethylene glycol 150°, 15+% sorbitol solution (70°)
5 Thialoe end 0.5
Purified water 40.5% Fragrance Appropriate amount [Formulation C] Monopotassium N-lauroylglutamate 25 Monopotassium N-myristoylglutamate 109
g Polyoxyethylene lauryl ether (5 mol K O) (HL B value 8.6)
7.5% polyoxyethylene polyoxypropylene copolymer (Pluronic L-64) (HLB value 15.0) 0.5
Thilauric acid 5%
Stearic acid 1% Propylene glycol 15% Maltitol solution (70%) 7% purified water 29% Fragrance
Appropriate amount [Formulation D] Monosodium N-lauroylglutamate 20%
Disodium N-valmitoylglutamate 5%
Hydrogenated castor oil EO adduct (80 mol) (HLB value 15.0) 0.
3% pentaglyceryl tetraoleate (HLB value 8.3) 5
% hydrogenated castor oil EO adduct (5 moles) (HLB value 6.0) 4%
honey wax
2 Typtylene glycol 15 Tiglycerin l〇-Ion exchange water 38.7fi scent-
・Adequate amount [Formulation E] Monosodium lauroyl aspartate 21%
Disodium N-stearoyl aspartate 4 Sodium N-lauroylmethyltaurate 5 Sodium saccharide tetraisostearate (HLB value 2.0), 1 polyoxyethylene oleyl ether (50 mol K O) (HL B value 17.6 )
8 Tyranoline
3-Glycyrrhizin
0.5s polyethylene glycol 1500
15% sorbitol solution (70 g)
l〇-Purified water 32.511I storage material appropriate amount

Claims (4)

[Claims] (1) A creamy skin cleanser containing N-acyl acidic amino acetate contains a high HLB nonionic surfactant with a hydrophilic lipophilic balance (HL B) value of 11 or more and an HLB that is liquid or paste-like at room temperature. Low HLB with value 101 or less
A creamy skin cleansing agent containing a nonionic surfactant. (2) The creamy skin cleanser according to claim 1, wherein the ratio of the high HLB nonionic surfactant to the low HLB nonionic surfactant is 1=30 to 15:1 (by weight). (3) High 1 (LB) The creamy skin cleanser according to claim 1, wherein the nonionic surfactant is a hydrogenated castor oil ethylene oxide adduct (60 mol) or/and an ethylene oxide propylene oxide copolymer. (4) The creamy skin cleanser according to claim 1, wherein the low HLB nonionic externally active agent is diglyceryl diisostearate or/and glyceryl dioleate.