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JPS57145898A - Novel n6, n6-dimethyladenosine derivative - Google Patents

Novel n6, n6-dimethyladenosine derivative

Info

Publication number
JPS57145898A
JPS57145898A JP3175881A JP3175881A JPS57145898A JP S57145898 A JPS57145898 A JP S57145898A JP 3175881 A JP3175881 A JP 3175881A JP 3175881 A JP3175881 A JP 3175881A JP S57145898 A JPS57145898 A JP S57145898A
Authority
JP
Japan
Prior art keywords
dimethyladenosine
derivative
alkenyl
alkyl
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3175881A
Other languages
Japanese (ja)
Inventor
Shintaro Arakawa
Shuichi Ogawa
Koji Miyazaki
Tetsuo Kato
Asao Murofushi
Hideo Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ARAKAWA CHIYOUTAROU KK
Arakawa Chotaro & Co
Original Assignee
ARAKAWA CHIYOUTAROU KK
Arakawa Chotaro & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ARAKAWA CHIYOUTAROU KK, Arakawa Chotaro & Co filed Critical ARAKAWA CHIYOUTAROU KK
Priority to JP3175881A priority Critical patent/JPS57145898A/en
Publication of JPS57145898A publication Critical patent/JPS57145898A/en
Pending legal-status Critical Current

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  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A derivative shown by the formulaI{A is S, R1, NHR2, piperazino[R1 is 2W20C alkyl, 2W6C alkenyl; R2 is H, OH, 1W20C alkyl, 2W6C alkenyl, 4W6C cycloalkyl which may have mono-substituted 1W4C (oxy)alkoxyl]}.
EXAMPLE: 8-n-Heptylamino-N6, N6-dimethyladenosine.
USE: Useful as an oral drug, injection, paraenteral drug such as suppository, etc., as an anodyne.
PROCESS: For example, an 8-halogeno-N6, N6-dimethyladenosine (e.g., 8-bromo-N6, N6-dimethyladenosine, etc.) shown by the formula II (X is Cl, Br, I, etc.) is reacted with an equimolarWten times the molarity of an amine shown by the formula III (R2' is as shown above) or piperazine (e.g., n-heptylamine, etc.) in a solvent of an alcohol in the presence of sodium methylate under boiling.
COPYRIGHT: (C)1982,JPO&Japio
JP3175881A 1981-03-05 1981-03-05 Novel n6, n6-dimethyladenosine derivative Pending JPS57145898A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3175881A JPS57145898A (en) 1981-03-05 1981-03-05 Novel n6, n6-dimethyladenosine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3175881A JPS57145898A (en) 1981-03-05 1981-03-05 Novel n6, n6-dimethyladenosine derivative

Publications (1)

Publication Number Publication Date
JPS57145898A true JPS57145898A (en) 1982-09-09

Family

ID=12339916

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3175881A Pending JPS57145898A (en) 1981-03-05 1981-03-05 Novel n6, n6-dimethyladenosine derivative

Country Status (1)

Country Link
JP (1) JPS57145898A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0152944A2 (en) * 1984-02-23 1985-08-28 Roche Diagnostics GmbH Use of adenosine derivatives as anti-allergic product and pharmaceuticals containing them
JPH0672895U (en) * 1993-03-29 1994-10-11 株式会社河合楽器製作所 Keyboard instrument packaging box

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0152944A2 (en) * 1984-02-23 1985-08-28 Roche Diagnostics GmbH Use of adenosine derivatives as anti-allergic product and pharmaceuticals containing them
US4704381A (en) * 1984-02-23 1987-11-03 Boehringer Mannheim Gmbh Use of adenosine derivatives as anti-allergic compounds and pharmaceutical compositions containing them
EP0152944A3 (en) * 1984-02-23 1989-03-22 Roche Diagnostics GmbH Use of adenosine derivatives as anti-allergic product and pharmaceuticals containing them
JPH0672895U (en) * 1993-03-29 1994-10-11 株式会社河合楽器製作所 Keyboard instrument packaging box

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