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JPS57145810A - Immunological activator containing lysophospholipid and preparation thereof - Google Patents

Immunological activator containing lysophospholipid and preparation thereof

Info

Publication number
JPS57145810A
JPS57145810A JP1339982A JP1339982A JPS57145810A JP S57145810 A JPS57145810 A JP S57145810A JP 1339982 A JP1339982 A JP 1339982A JP 1339982 A JP1339982 A JP 1339982A JP S57145810 A JPS57145810 A JP S57145810A
Authority
JP
Japan
Prior art keywords
lysophospholipid
immunological
alkoxyl
acyloxy
incorporating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1339982A
Other languages
Japanese (ja)
Other versions
JPS6348848B2 (en
Inventor
Hiroshi Kodama
Kaoru Ooyama
Ryusaku Shimizu
Masao Nakabayashi
Yoshifumi Nakajima
Takashi Sano
Masaaki Shibata
Kiyoshi Goda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Priority to JP1339982A priority Critical patent/JPS57145810A/en
Publication of JPS57145810A publication Critical patent/JPS57145810A/en
Publication of JPS6348848B2 publication Critical patent/JPS6348848B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: To obtain a highly safe immunological activator capable of reducing the hemolytic action without affecting the immunological activating action of a lysophospholipid and angiopathy even on the continued parenteral use, by incorporating the lysophospholipid with a phospholipid.
CONSTITUTION: An immunological activator obtained by incorporating (A) a lysophospholipid, preferably a compound expressed by the formula (R1 is 5W22C acyloxy or 5W22C alkoxyl; R2 is H, OH, 1W5C acyloxy, 1W5C alkoxyl or R1 and R2 are mutually exchangeable; R3 is H or 1W5C alkyl) or a lysophospholipid consisting thereof essentially, particularly the compound obtained by decomposing lecithin, and (B) preferably a naturally occurring phospholipid, and in the dosage form of a dispersion in which the components are dispersed in a lipid cytoplasmic reticula having a particle diameter ≤0.5μ. The immunological activator may contain (C) a fat or oil, particularly edible oil, or (D) fatty emulsion.
COPYRIGHT: (C)1982,JPO&Japio
JP1339982A 1982-02-01 1982-02-01 Immunological activator containing lysophospholipid and preparation thereof Granted JPS57145810A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1339982A JPS57145810A (en) 1982-02-01 1982-02-01 Immunological activator containing lysophospholipid and preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1339982A JPS57145810A (en) 1982-02-01 1982-02-01 Immunological activator containing lysophospholipid and preparation thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP11726279A Division JPS5840929B2 (en) 1979-03-05 1979-09-14 Anticancer agent containing lysolecithin and phospholipid and its manufacturing method

Publications (2)

Publication Number Publication Date
JPS57145810A true JPS57145810A (en) 1982-09-09
JPS6348848B2 JPS6348848B2 (en) 1988-09-30

Family

ID=11832034

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1339982A Granted JPS57145810A (en) 1982-02-01 1982-02-01 Immunological activator containing lysophospholipid and preparation thereof

Country Status (1)

Country Link
JP (1) JPS57145810A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001095914A1 (en) * 2000-06-14 2001-12-20 William Leslie Porter Lipids for modulating immune response
JP2016518313A (en) * 2013-03-12 2016-06-23 アリビオ， インコーポレーテッド Lipid nanomaterial containing lysophosphatidylcholine or derivative thereof, and method for producing the same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001095914A1 (en) * 2000-06-14 2001-12-20 William Leslie Porter Lipids for modulating immune response
JP2016518313A (en) * 2013-03-12 2016-06-23 アリビオ， インコーポレーテッド Lipid nanomaterial containing lysophosphatidylcholine or derivative thereof, and method for producing the same

Also Published As

Publication number Publication date
JPS6348848B2 (en) 1988-09-30

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