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JPS5690042A - Diphenyl ether derivative and its preparation - Google Patents

Diphenyl ether derivative and its preparation

Info

Publication number
JPS5690042A
JPS5690042A JP16756279A JP16756279A JPS5690042A JP S5690042 A JPS5690042 A JP S5690042A JP 16756279 A JP16756279 A JP 16756279A JP 16756279 A JP16756279 A JP 16756279A JP S5690042 A JPS5690042 A JP S5690042A
Authority
JP
Japan
Prior art keywords
formula
compound
preparation
diphenyl ether
ether derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16756279A
Other languages
Japanese (ja)
Other versions
JPS6252738B2 (en
Inventor
Masuo Koizumi
Kazuo Sasahara
Narimitsu Honda
Yasushi Murakami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP16756279A priority Critical patent/JPS5690042A/en
Publication of JPS5690042A publication Critical patent/JPS5690042A/en
Publication of JPS6252738B2 publication Critical patent/JPS6252738B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A compound expressed by formula I (R1 is H, 1-2 halogens, lower alkyl or lower alkoxyl; R2 is lower alkyl).
EXAMPLE: Ethyl 4-(2-formyl-6-methoxyphenoxy)-3-nitrobenzoate.
USE: An antilipemic agent and an intermediate for preparing a lipid lowering agent.
PROCESS: A compound of formula II (R3 is H or alkali metal) is reacted with a compound of formula III (X is halogen) in the absence or presence of a solvent, e.g. toluene, xylene or chlorobenzene, at 100W200°C to give the compound of formula I. If R3 in formula II is H, the compounds are reacted preferably in the presence of a dehydrohalogenating agent, e.g. an alkali metal hydroxide or carbonate.
COPYRIGHT: (C)1981,JPO&Japio
JP16756279A 1979-12-25 1979-12-25 Diphenyl ether derivative and its preparation Granted JPS5690042A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16756279A JPS5690042A (en) 1979-12-25 1979-12-25 Diphenyl ether derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16756279A JPS5690042A (en) 1979-12-25 1979-12-25 Diphenyl ether derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS5690042A true JPS5690042A (en) 1981-07-21
JPS6252738B2 JPS6252738B2 (en) 1987-11-06

Family

ID=15852021

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16756279A Granted JPS5690042A (en) 1979-12-25 1979-12-25 Diphenyl ether derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5690042A (en)

Also Published As

Publication number Publication date
JPS6252738B2 (en) 1987-11-06

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