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JPS568317A - Preventive and remedy for complicating disease of diabetes mellitus - Google Patents

Preventive and remedy for complicating disease of diabetes mellitus

Info

Publication number
JPS568317A
JPS568317A JP8482779A JP8482779A JPS568317A JP S568317 A JPS568317 A JP S568317A JP 8482779 A JP8482779 A JP 8482779A JP 8482779 A JP8482779 A JP 8482779A JP S568317 A JPS568317 A JP S568317A
Authority
JP
Japan
Prior art keywords
remedy
preventive
deabetic
diabetes mellitus
complicating disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8482779A
Other languages
Japanese (ja)
Other versions
JPH025733B2 (en
Inventor
Junichi Iwao
Masayuki Ooya
Tadashi Iso
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Priority to JP8482779A priority Critical patent/JPS568317A/en
Priority to US06/104,970 priority patent/US4347371A/en
Priority to AU54024/79A priority patent/AU536307B2/en
Priority to CA342,420A priority patent/CA1128517A/en
Priority to SE7910554A priority patent/SE446864B/en
Priority to CH11528/79A priority patent/CH647769A5/en
Priority to IT28440/79A priority patent/IT1127323B/en
Priority to NL7909334A priority patent/NL7909334A/en
Priority to FR7932060A priority patent/FR2445324A1/en
Priority to DE19792952594 priority patent/DE2952594A1/en
Priority to GB7944544A priority patent/GB2042517B/en
Priority to US06/186,271 priority patent/US4410542A/en
Publication of JPS568317A publication Critical patent/JPS568317A/en
Publication of JPH025733B2 publication Critical patent/JPH025733B2/ja
Granted legal-status Critical Current

Links

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  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: A drug having the effect of preventing and remedying a complicating disease of diabetes mellitus, comprising a N-mercaptoacylamino acid or its derivative as an active ingredient.
CONSTITUTION: A preventive and remedy for a complicating disease of deabetes mellitus (e.g., deabetic cataract, deabetic retinopathy, deabetic nephropathy, deabetic neuropathy, etc.) comprising a N-mercaptoacylamino acid shown by the formula (Q1 and Q2 are S, O, or methylene with the proviso that they are not S or O simultaneously; Y is 1W3C alkylene; R1 is H, lower alkyl, or higher alkyl; R2 is R1 or R1-(0-, etc.; R3 is H or lower alkyl, etc.; n is 1 or 2) and its reactive derivative. A dose is 1W500mg daily, preferably 10W1,000mg and the preventive and remedy is administered one or several times a day. (4R)-3-(S-benzoylmecrcaptoacetyl)-4-thiazolidinecarboxylic acid, etc. may be cited as the compound shown by the formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP8482779A 1978-12-30 1979-07-03 Preventive and remedy for complicating disease of diabetes mellitus Granted JPS568317A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
JP8482779A JPS568317A (en) 1979-07-03 1979-07-03 Preventive and remedy for complicating disease of diabetes mellitus
US06/104,970 US4347371A (en) 1978-12-30 1979-12-18 Disulfide compounds
AU54024/79A AU536307B2 (en) 1978-12-30 1979-12-19 Disulphide derivatives of pyrrolidine and thiazolidine
CA342,420A CA1128517A (en) 1978-12-30 1979-12-20 Disulfide compounds
SE7910554A SE446864B (en) 1978-12-30 1979-12-20 Disulfide compounds, procedure for producing the same and pharmaceutical composition containing said disulfide compounds
CH11528/79A CH647769A5 (en) 1978-12-30 1979-12-28 DISULFID COMPOUNDS.
IT28440/79A IT1127323B (en) 1978-12-30 1979-12-28 COMPOUNDS CONSTITUTED FROM DISULFURI
NL7909334A NL7909334A (en) 1978-12-30 1979-12-28 METHOD FOR PREPARING A BLOOD PRESSURE REDUCING AGENT BASED ON DISULFIDE COMPOUNDS, THE MEDICINE PREPARED AND A METHOD FOR PREPARING THE ACTIVE COMPONENT.
FR7932060A FR2445324A1 (en) 1978-12-30 1979-12-28 NOVEL DISULFIDE DERIVATIVES CONTAINING A PYRROLIDINE OR THIAZOLIDINE CYCLE USEFUL AS ANTIHYPERTENSORS AND FOR PREVENTING AND TREATING DIABETES COMPLICATIONS AND METHODS FOR THEIR PREPARATION
DE19792952594 DE2952594A1 (en) 1978-12-30 1979-12-28 DISULFID COMPOUNDS
GB7944544A GB2042517B (en) 1978-12-30 1979-12-28 Disulphide compounds
US06/186,271 US4410542A (en) 1978-12-30 1980-09-11 Disulfide compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8482779A JPS568317A (en) 1979-07-03 1979-07-03 Preventive and remedy for complicating disease of diabetes mellitus

Publications (2)

Publication Number Publication Date
JPS568317A true JPS568317A (en) 1981-01-28
JPH025733B2 JPH025733B2 (en) 1990-02-05

Family

ID=13841589

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8482779A Granted JPS568317A (en) 1978-12-30 1979-07-03 Preventive and remedy for complicating disease of diabetes mellitus

Country Status (1)

Country Link
JP (1) JPS568317A (en)

Also Published As

Publication number Publication date
JPH025733B2 (en) 1990-02-05

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