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JPS5668610A - Antitumorigenic agent containing napthalenesulfonamide as effective component - Google Patents

Antitumorigenic agent containing napthalenesulfonamide as effective component

Info

Publication number
JPS5668610A
JPS5668610A JP14382279A JP14382279A JPS5668610A JP S5668610 A JPS5668610 A JP S5668610A JP 14382279 A JP14382279 A JP 14382279A JP 14382279 A JP14382279 A JP 14382279A JP S5668610 A JPS5668610 A JP S5668610A
Authority
JP
Japan
Prior art keywords
effective component
formula
antitumorigenic
napthalenesulfonamide
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14382279A
Other languages
Japanese (ja)
Inventor
Hiroyoshi Hidaka
Hitoshi Ito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP14382279A priority Critical patent/JPS5668610A/en
Publication of JPS5668610A publication Critical patent/JPS5668610A/en
Pending legal-status Critical Current

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: An antitumorigenic agent that contains a napthalenesulfonamide derivative as an effective component, thus showing low toxicity and high antitumorigenic activity and being used orally or parenterally.
CONSTITUTION: An antitumorigenic agent that contains a naphthalenesulfoneamide derivative of formula I [X is H, halogen; So2NHR connects to the 1 or 2 position in the naphthalene ring; R is H, amino, -(CH2)mNH2, formula II; m is 1W10; n is 4W6] such as N-(5-aminobutyl)-5-chloro-1-naphthalenesulfonamide (A-5) as an effective component. The dose is usually 10W100mg a day. The compound of formula I is obtained by reaction of a naphthalenesulfonic acid derivative of formula III (X1 is halogen) with an amine of R-NH2 or its acylated product and, when necessary, subsequent deacylation of the amino-protecting group.
COPYRIGHT: (C)1981,JPO&Japio
JP14382279A 1979-11-08 1979-11-08 Antitumorigenic agent containing napthalenesulfonamide as effective component Pending JPS5668610A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14382279A JPS5668610A (en) 1979-11-08 1979-11-08 Antitumorigenic agent containing napthalenesulfonamide as effective component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14382279A JPS5668610A (en) 1979-11-08 1979-11-08 Antitumorigenic agent containing napthalenesulfonamide as effective component

Publications (1)

Publication Number Publication Date
JPS5668610A true JPS5668610A (en) 1981-06-09

Family

ID=15347756

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14382279A Pending JPS5668610A (en) 1979-11-08 1979-11-08 Antitumorigenic agent containing napthalenesulfonamide as effective component

Country Status (1)

Country Link
JP (1) JPS5668610A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681899A (en) * 1985-03-29 1987-07-21 Ohnishi S Tsuyoshi Method of preventing the growth of malaria parasites in erythrocytes
US5707985A (en) * 1995-06-07 1998-01-13 Tanabe Seiyaku Co. Ltd. Naphthyl-, quinolyl- and isoquinolyl- sulfonamide derivatives as cell adhesion modulators

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681899A (en) * 1985-03-29 1987-07-21 Ohnishi S Tsuyoshi Method of preventing the growth of malaria parasites in erythrocytes
US5707985A (en) * 1995-06-07 1998-01-13 Tanabe Seiyaku Co. Ltd. Naphthyl-, quinolyl- and isoquinolyl- sulfonamide derivatives as cell adhesion modulators

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