JPS5646839A - 4-allyloxy-3-chlorophenylacetic acid-cyclodextrin clathrate compound - Google Patents
4-allyloxy-3-chlorophenylacetic acid-cyclodextrin clathrate compoundInfo
- Publication number
- JPS5646839A JPS5646839A JP12316179A JP12316179A JPS5646839A JP S5646839 A JPS5646839 A JP S5646839A JP 12316179 A JP12316179 A JP 12316179A JP 12316179 A JP12316179 A JP 12316179A JP S5646839 A JPS5646839 A JP S5646839A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- cyclodextrin
- allyloxy
- chlorophenylacetic acid
- kneading
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To titled compound almost free from irritant odor and taste, useful as an antiphlogistic analgesic agent of various administration forms, and obtained by including 4-allyloxy-3-chlorophenylacetic acid in cyclodextrin.
CONSTITUTION: The titled clathrate compound is prepared by including 4-allyloxy-3-chloro-phenylacetic acid (A) in cyclodextrin. The inclusion is preferably carried out by the solution process or the kneading process. In the sloution process, the objective compound is prepared by adding the compound (A) or its alcohol solution, etc. to the saturated aqueous solution of cyclodextrin, and stirring the mixture at 20W60°C for 5W10hr; and in the kneading process, the powdery product is obtained by adding the compound (A) to an aqueous paste of cyclodextrin, kneading the mixture at 20W60°C for 3W8hr, and drying the product.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12316179A JPS5646839A (en) | 1979-09-27 | 1979-09-27 | 4-allyloxy-3-chlorophenylacetic acid-cyclodextrin clathrate compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12316179A JPS5646839A (en) | 1979-09-27 | 1979-09-27 | 4-allyloxy-3-chlorophenylacetic acid-cyclodextrin clathrate compound |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5646839A true JPS5646839A (en) | 1981-04-28 |
Family
ID=14853684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12316179A Pending JPS5646839A (en) | 1979-09-27 | 1979-09-27 | 4-allyloxy-3-chlorophenylacetic acid-cyclodextrin clathrate compound |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5646839A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4762702A (en) * | 1984-11-05 | 1988-08-09 | Gerhard Gergely | Pharmaceutical preparation containing ibuprofen and a process for its preparation |
-
1979
- 1979-09-27 JP JP12316179A patent/JPS5646839A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4762702A (en) * | 1984-11-05 | 1988-08-09 | Gerhard Gergely | Pharmaceutical preparation containing ibuprofen and a process for its preparation |
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