JPS5635991A - Preparation of l-alanine - Google Patents
Preparation of l-alanineInfo
- Publication number
- JPS5635991A JPS5635991A JP11037079A JP11037079A JPS5635991A JP S5635991 A JPS5635991 A JP S5635991A JP 11037079 A JP11037079 A JP 11037079A JP 11037079 A JP11037079 A JP 11037079A JP S5635991 A JPS5635991 A JP S5635991A
- Authority
- JP
- Japan
- Prior art keywords
- tank
- aspartic acid
- fixed
- enzyme
- alanine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To synthesize L-alanine efficiently from fumaric acid and ammonia through L-aspartic acid, by adding fixed aspartase and fixed L-aspartic acid-β- decarboxylase to a series multistage reactor.
CONSTITUTION: Fixed aspartase and fixed L-aspartic acid-β-decarboxylase are added to individual tanks of series multistage reactor forming one continuous system, and reaction conditions, e.g., activity ratio of enzyme, pH, etc. are set properly in such a way that these conditions are different from tank to tank. A solution containing ammonium fumarate and pyridoxal phosphate is fed to a tank of the first stage continuously, the product, L-alanine, is recovered directly from a tank of the last stage without separating the intermediate, L-aspartic acid. The enzyme (mold) to be used is obtained by fixing a well-known enzyme by a well-known method.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11037079A JPS5635991A (en) | 1979-08-31 | 1979-08-31 | Preparation of l-alanine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11037079A JPS5635991A (en) | 1979-08-31 | 1979-08-31 | Preparation of l-alanine |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5635991A true JPS5635991A (en) | 1981-04-08 |
Family
ID=14534066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11037079A Pending JPS5635991A (en) | 1979-08-31 | 1979-08-31 | Preparation of l-alanine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5635991A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63214188A (en) * | 1987-03-04 | 1988-09-06 | Hitachi Ltd | Production of amino acid decarboxylation product and apparatus therefor |
US5116743A (en) * | 1989-02-06 | 1992-05-26 | Mitsubishi Petrochemical Co., Ltd. | L-alanine production with two microorganisms having fumarase inactivity in a single reaction tank |
US5814387A (en) * | 1995-01-24 | 1998-09-29 | Orihara Manufacturing Co., Ltd. | Rubber band for repairs and method therefor |
CN105624223A (en) * | 2014-10-29 | 2016-06-01 | 宜兴市前成生物有限公司 | Method for preparing DL-alanine and D-alanine |
-
1979
- 1979-08-31 JP JP11037079A patent/JPS5635991A/en active Pending
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63214188A (en) * | 1987-03-04 | 1988-09-06 | Hitachi Ltd | Production of amino acid decarboxylation product and apparatus therefor |
JPH0545236B2 (en) * | 1987-03-04 | 1993-07-08 | Hitachi Ltd | |
US5116743A (en) * | 1989-02-06 | 1992-05-26 | Mitsubishi Petrochemical Co., Ltd. | L-alanine production with two microorganisms having fumarase inactivity in a single reaction tank |
US5814387A (en) * | 1995-01-24 | 1998-09-29 | Orihara Manufacturing Co., Ltd. | Rubber band for repairs and method therefor |
CN105624223A (en) * | 2014-10-29 | 2016-06-01 | 宜兴市前成生物有限公司 | Method for preparing DL-alanine and D-alanine |
CN105624223B (en) * | 2014-10-29 | 2019-09-03 | 宜兴市前成生物有限公司 | A method of preparing DL-Alanine and D-alanine |
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