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JPS56158788A - Cephalosporin compound for oral use - Google Patents

Cephalosporin compound for oral use

Info

Publication number
JPS56158788A
JPS56158788A JP6305680A JP6305680A JPS56158788A JP S56158788 A JPS56158788 A JP S56158788A JP 6305680 A JP6305680 A JP 6305680A JP 6305680 A JP6305680 A JP 6305680A JP S56158788 A JPS56158788 A JP S56158788A
Authority
JP
Japan
Prior art keywords
compound
formula
amino
carboxylic acid
cephem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6305680A
Other languages
Japanese (ja)
Inventor
Hideo Nakao
Shinichi Sugawara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP6305680A priority Critical patent/JPS56158788A/en
Publication of JPS56158788A publication Critical patent/JPS56158788A/en
Pending legal-status Critical Current

Links

Landscapes

  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A cephem compound (syn isomer) of formula I (R is lower alkyl other than t-butyl) and a salt thereof.
EXAMPLE: Isobutyryloxymethyl 7-[ 2-( 2-amino -4- thiazolyl )-2-methoxyiminoacetmido]3-methyl-3-cephem-4-carboxylate.
USE: An antimicrobial agent, readily absorbable from the digestive tract, and capable of giving a high concentration of a carboxylic acid type compound in blood due to the rapid decomposition of the ester part at the 4-position into the carboxylic acid in the living body.
PROCESS: A compound of formula II or an acid addition salt thereof is reacted with a carboxylic acid of formula III (X is amino or protected amino) or a reactive derivative thereof to give a compound of formula IV, and the group (X) is converted into an amino group to afford the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP6305680A 1980-05-13 1980-05-13 Cephalosporin compound for oral use Pending JPS56158788A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6305680A JPS56158788A (en) 1980-05-13 1980-05-13 Cephalosporin compound for oral use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6305680A JPS56158788A (en) 1980-05-13 1980-05-13 Cephalosporin compound for oral use

Publications (1)

Publication Number Publication Date
JPS56158788A true JPS56158788A (en) 1981-12-07

Family

ID=13218291

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6305680A Pending JPS56158788A (en) 1980-05-13 1980-05-13 Cephalosporin compound for oral use

Country Status (1)

Country Link
JP (1) JPS56158788A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01265093A (en) * 1988-10-12 1989-10-23 Sankyo Co Ltd Cephalosporin compound for oral use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01265093A (en) * 1988-10-12 1989-10-23 Sankyo Co Ltd Cephalosporin compound for oral use

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