JPS56115768A - Serine derivative and its preparation - Google Patents
Serine derivative and its preparationInfo
- Publication number
- JPS56115768A JPS56115768A JP1800780A JP1800780A JPS56115768A JP S56115768 A JPS56115768 A JP S56115768A JP 1800780 A JP1800780 A JP 1800780A JP 1800780 A JP1800780 A JP 1800780A JP S56115768 A JPS56115768 A JP S56115768A
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- formula
- compound
- benzylserine
- benzylthiocarbonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:An N-benzylthiocarbonyl-O-benzylserine compound of formula I (R1 is phenyl, phenyl substituted by 1W2 lower alkyl groups; R2 is phenyl or phenyl which is substituted by halogen, etc.; R3 is hydroxyl group, lower alkoxyl group, etc.) or a salt thereof.
EXAMPLE: N-(4-Nitrobenzylthiocarbonyl)-O-benzyl-L-serine.
USE: A remedy for lipemia having a powerful antilipemic action and with slight side effects, e.g. hepatic dysfunction.
PROCESS: An O-benzylserine compound of formula II is reacted with a benzylthiocarbonyl halode of formula III (X1 is halogen) in a suitable solvent in the presence of a deacidifying agent, e.g. an inorganic base, at -50W50°C to give a compound of formula IV.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1800780A JPS56115768A (en) | 1980-02-15 | 1980-02-15 | Serine derivative and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1800780A JPS56115768A (en) | 1980-02-15 | 1980-02-15 | Serine derivative and its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS56115768A true JPS56115768A (en) | 1981-09-11 |
Family
ID=11959615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1800780A Pending JPS56115768A (en) | 1980-02-15 | 1980-02-15 | Serine derivative and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56115768A (en) |
-
1980
- 1980-02-15 JP JP1800780A patent/JPS56115768A/en active Pending
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