JPS5583766A - Isoxazolin-3-one derivative - Google Patents
Isoxazolin-3-one derivativeInfo
- Publication number
- JPS5583766A JPS5583766A JP15792578A JP15792578A JPS5583766A JP S5583766 A JPS5583766 A JP S5583766A JP 15792578 A JP15792578 A JP 15792578A JP 15792578 A JP15792578 A JP 15792578A JP S5583766 A JPS5583766 A JP S5583766A
- Authority
- JP
- Japan
- Prior art keywords
- lower alkyl
- isoxazolin
- halogen
- derivative
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:An isoxazolin-3-one derivative of formula I (R1 is H, lower alkyl, or halogen; R2 is H, lower alkyl, aryl, or heterocyclic group; or R1 and R2 together may form a hydrocarbon ring with adjacent carbon atom; Y is H, or II; R3,4,6,7 are H, lower alkyl or aryl; R5 is H or lower alkyl; X is H, OH, or halogen).
EXAMPLE: 4-Chloro-2-(2,3-dihydroxy-n-propyl)-5-phenyl-4-isoxazolin-3-one.
USE: Anti-phlogistics, analgesics, and antipyretics.
PROCESS: The objective compound I wherein Y is Ya is prepared by reacting a compound III with a compound IV [Ya is H or group V (Xa is H or OH); Z is halogen] in an inert solvent, in the presence or absence of a base.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15792578A JPS5583766A (en) | 1978-12-18 | 1978-12-18 | Isoxazolin-3-one derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15792578A JPS5583766A (en) | 1978-12-18 | 1978-12-18 | Isoxazolin-3-one derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5583766A true JPS5583766A (en) | 1980-06-24 |
Family
ID=15660455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15792578A Pending JPS5583766A (en) | 1978-12-18 | 1978-12-18 | Isoxazolin-3-one derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5583766A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0273744A2 (en) * | 1986-12-26 | 1988-07-06 | Sankyo Company Limited | Centrally-acting muscle relaxants |
| US6743815B2 (en) | 1998-08-07 | 2004-06-01 | Chiron Corporation | Estrogen receptor modulators |
-
1978
- 1978-12-18 JP JP15792578A patent/JPS5583766A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0273744A2 (en) * | 1986-12-26 | 1988-07-06 | Sankyo Company Limited | Centrally-acting muscle relaxants |
| US6743815B2 (en) | 1998-08-07 | 2004-06-01 | Chiron Corporation | Estrogen receptor modulators |
| US6869969B2 (en) | 1998-08-07 | 2005-03-22 | Chiron Corporation | Estrogen receptor modulators |
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