JPS55345A - 2-iminobenzthiazoline derivative - Google Patents
2-iminobenzthiazoline derivativeInfo
- Publication number
- JPS55345A JPS55345A JP14486278A JP14486278A JPS55345A JP S55345 A JPS55345 A JP S55345A JP 14486278 A JP14486278 A JP 14486278A JP 14486278 A JP14486278 A JP 14486278A JP S55345 A JPS55345 A JP S55345A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- hydroxyethyl
- reacted
- compound shown
- iminobenzthiazoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Thiazole And Isothizaole Compounds (AREA)
Abstract
NEW MATERIAL:5-chloro-3-[4-(2-hydroxyethyl)-1-piperazinyl] carbonylmethyl- 2-iminobenzthiazoline shown by the formula II.
USE: A synthetic intermediate of 5-chloro-3-[4-(2-hydroxyethyl)-1-piperazinyl] carbonylmethyl-2-benzthiazolinone, a medicine having antiinflammatory and pain-killing effect.
PROCESS: m-Chloroaniline shown by the formula I is reacted with a thioyanate (e.g., sodium salt) to give a compound shown by the formula V, which is subjected to ring opening by bromine to prepare a compound shown by the formula IV. This compound is then reacted with a monohalogenated acetate to give a compound shown by the formula III, which is reacted with 1-(2-hydroxyethyl) piperazine to prepare the compound shown by the formula II.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14486278A JPS55345A (en) | 1978-11-22 | 1978-11-22 | 2-iminobenzthiazoline derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14486278A JPS55345A (en) | 1978-11-22 | 1978-11-22 | 2-iminobenzthiazoline derivative |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52101463A Division JPS5811951B2 (en) | 1977-08-24 | 1977-08-24 | Method for producing 2-benzothiazolinone derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55345A true JPS55345A (en) | 1980-01-05 |
Family
ID=15372119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14486278A Pending JPS55345A (en) | 1978-11-22 | 1978-11-22 | 2-iminobenzthiazoline derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55345A (en) |
-
1978
- 1978-11-22 JP JP14486278A patent/JPS55345A/en active Pending
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