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JPS549300A - Method of preparing hydroxynormorphin compound - Google Patents

Method of preparing hydroxynormorphin compound

Info

Publication number
JPS549300A
JPS549300A JP7531078A JP7531078A JPS549300A JP S549300 A JPS549300 A JP S549300A JP 7531078 A JP7531078 A JP 7531078A JP 7531078 A JP7531078 A JP 7531078A JP S549300 A JPS549300 A JP S549300A
Authority
JP
Japan
Prior art keywords
hydroxynormorphin
preparing
compound
preparing hydroxynormorphin
hydroxynormorphin compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7531078A
Other languages
Japanese (ja)
Inventor
Harutensutain Yohanesu
Sutajingaa Geruharuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of JPS549300A publication Critical patent/JPS549300A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP7531078A 1977-06-21 1978-06-21 Method of preparing hydroxynormorphin compound Pending JPS549300A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772727805 DE2727805A1 (en) 1977-06-21 1977-06-21 METHOD FOR PRODUCING OXYNORMORPHONE

Publications (1)

Publication Number Publication Date
JPS549300A true JPS549300A (en) 1979-01-24

Family

ID=6011952

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7531078A Pending JPS549300A (en) 1977-06-21 1978-06-21 Method of preparing hydroxynormorphin compound

Country Status (7)

Country Link
JP (1) JPS549300A (en)
DE (1) DE2727805A1 (en)
FI (1) FI781962A (en)
FR (1) FR2395269A1 (en)
GB (1) GB2000137B (en)
HU (1) HU177923B (en)
NL (1) NL7806658A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014514339A (en) * 2011-05-06 2014-06-19 ブロック ユニバーシティ Process for the preparation of morphine analogues by metal-catalyzed N-demethylation / functionalization and intramolecular group transfer
JP2021514971A (en) * 2018-02-23 2021-06-17 ロデス テクノロジーズ New opioid compounds and their use

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795813A (en) * 1981-08-17 1989-01-03 The Florida Board Of Regents On Behalf Of The Florida State University Synthesis of derivatives of codeine and other 3-O-alkylmorphines
DE3581423D1 (en) * 1984-03-27 1991-02-28 Mallinckrodt Inc MANUFACTURE OF NOROXYMORPHONE FROM MORPHINE.
FR2564838B1 (en) * 1984-05-25 1986-11-07 Sanofi Sa PROCESS FOR DEALKYLATION OF ALKALOIDS AND INTERMEDIATES
HU197750B (en) * 1984-07-17 1989-05-29 Alkaloida Vegyeszeti Gyar Process for n-demethylation of morphine alkaloids
WO2006084389A1 (en) 2005-02-11 2006-08-17 Cilag Ltd. Method for purifying noroxymorphone compounds
GB2471802B (en) * 2006-05-25 2011-02-16 Alpharma Chemical process
GB2444052A (en) * 2006-05-25 2008-05-28 Alpharma Aps Processes of preparing morphinan derivatives such as naltrexone and naloxone comprising O- and N-demethylation and reductive alkylation steps
GB2438401A (en) * 2006-05-25 2007-11-28 Alpharma Aps Preparation of morphinan derivatives comprising N-demethylation, reductive amination and O-demethylation steps
CA2802295C (en) 2010-06-11 2016-09-20 Rhodes Technologies Transition metal-catalyzed processes for the preparation of n-allyl compounds and use thereof
JP2013529595A (en) 2010-06-11 2013-07-22 ローズ テクノロジーズ Method for N-dealkylation of tertiary amines
ES2701855T3 (en) 2016-05-31 2019-02-26 Alcaliber Investig Desarrollo E Innovacion Slu Process for obtaining 3,14-diacetyloxymorphona from oripavine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905981A (en) * 1973-10-12 1975-09-16 Research Corp N-dealkylation of tertiary amines

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014514339A (en) * 2011-05-06 2014-06-19 ブロック ユニバーシティ Process for the preparation of morphine analogues by metal-catalyzed N-demethylation / functionalization and intramolecular group transfer
US9533993B2 (en) 2011-05-06 2017-01-03 Brock University Process for the preparation of morphine analogs via metal catalyzed N-demethylation/functionalization and intramolecular group transfer
JP2021514971A (en) * 2018-02-23 2021-06-17 ロデス テクノロジーズ New opioid compounds and their use
US11845759B2 (en) 2018-02-23 2023-12-19 Rhodes Technologies Opioid compounds and uses thereof

Also Published As

Publication number Publication date
FI781962A (en) 1978-12-22
FR2395269B1 (en) 1983-06-10
DE2727805A1 (en) 1979-01-04
FR2395269A1 (en) 1979-01-19
GB2000137A (en) 1979-01-04
HU177923B (en) 1982-01-28
GB2000137B (en) 1982-01-06
NL7806658A (en) 1978-12-27

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