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JPS5488252A - Manufacture of 16 alphaaalkylated steroid - Google Patents

Manufacture of 16 alphaaalkylated steroid

Info

Publication number
JPS5488252A
JPS5488252A JP15429478A JP15429478A JPS5488252A JP S5488252 A JPS5488252 A JP S5488252A JP 15429478 A JP15429478 A JP 15429478A JP 15429478 A JP15429478 A JP 15429478A JP S5488252 A JPS5488252 A JP S5488252A
Authority
JP
Japan
Prior art keywords
alphaaalkylated
steroid
manufacture
alphaaalkylated steroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15429478A
Other languages
Japanese (ja)
Other versions
JPS6225158B2 (en
Inventor
Niifu Giyuntaa
Eederu Ururitsuhi
Hatsufueru Guregooru
Zaueru Geruharuto
Nikoruzoon Rooberuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of JPS5488252A publication Critical patent/JPS5488252A/en
Publication of JPS6225158B2 publication Critical patent/JPS6225158B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
JP15429478A 1977-12-19 1978-12-15 Manufacture of 16 alphaaalkylated steroid Granted JPS5488252A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772757157 DE2757157C3 (en) 1977-12-19 1977-12-19 Process for the preparation of 16 a -alkylated steroids

Publications (2)

Publication Number Publication Date
JPS5488252A true JPS5488252A (en) 1979-07-13
JPS6225158B2 JPS6225158B2 (en) 1987-06-01

Family

ID=6026799

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15429478A Granted JPS5488252A (en) 1977-12-19 1978-12-15 Manufacture of 16 alphaaalkylated steroid

Country Status (2)

Country Link
JP (1) JPS5488252A (en)
DE (1) DE2757157C3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6069096A (en) * 1983-08-02 1985-04-19 リサ−チ・コ−ポレイシヨン Novel steroid

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6908910B2 (en) 1993-08-06 2005-06-21 The Children's Medical Center Corporation Estrogenic compounds as anti-mitotic agents
US5504074A (en) 1993-08-06 1996-04-02 Children's Medical Center Corporation Estrogenic compounds as anti-angiogenic agents
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US7087592B1 (en) 1999-08-23 2006-08-08 Entre Med, Inc. Compositions comprising purified 2-methoxyestradiol and methods of producing same
MXPA03000845A (en) 2000-07-28 2004-04-05 Akzo Nobel Nv 16alpha-methyl or ethyl substituted estrogens.
US7135581B2 (en) 2000-08-18 2006-11-14 Entremed, Inc. Antiangiogenic agents
CA2563704A1 (en) 2004-05-04 2005-11-24 Children's Medical Center Corporation Methods and compositions for treatment of preeclampsia
UA89964C2 (en) 2004-09-08 2010-03-25 Н.В. Органон 15beta-substituted steroids having selective estrogenic activity
JP2009530388A (en) 2006-03-20 2009-08-27 エントレメッド インコーポレイテッド Disease-modifying anti-arthritic activity of 2-methoxyestradiol

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6069096A (en) * 1983-08-02 1985-04-19 リサ−チ・コ−ポレイシヨン Novel steroid

Also Published As

Publication number Publication date
DE2757157B2 (en) 1980-02-21
DE2757157A1 (en) 1979-06-21
JPS6225158B2 (en) 1987-06-01
DE2757157C3 (en) 1980-10-09

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