JPS5444034A - Easily absorbable nifedipine composition and anti- stenocardia containing said composition - Google Patents
Easily absorbable nifedipine composition and anti- stenocardia containing said compositionInfo
- Publication number
- JPS5444034A JPS5444034A JP11081277A JP11081277A JPS5444034A JP S5444034 A JPS5444034 A JP S5444034A JP 11081277 A JP11081277 A JP 11081277A JP 11081277 A JP11081277 A JP 11081277A JP S5444034 A JPS5444034 A JP S5444034A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- nifedipine
- infiltrated
- stenocardia
- easily absorbable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: To provide an easily absorbable nifedipine composition and an antistenocardia containing said composition, composed of a polyethylene glycol solution of nifedipine infiltrated into a porous material.
CONSTITUTION: Nifedipine[1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridine dicarboxylic acid dimethyl ester]is dissolved in a polyethylene glycol having an average molecular weight of 200W600 to the highest concentration possible. The solution is infiltrated into a porous carrier which can be permissible for medical use, such as metasilicic acid, magnesium aluminate, porous silica, etc., to such an extent that the increment of the angle of repose does not exceed 5°. The composition thus obtained is formed to a desired from using arbitrary diluent, etc.
EFFECT: High absorbability to the body; excellent light stability.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11081277A JPS5444034A (en) | 1977-09-14 | 1977-09-14 | Easily absorbable nifedipine composition and anti- stenocardia containing said composition |
ZA00783286A ZA783286B (en) | 1977-09-14 | 1978-06-08 | Pharmaceutical preparation containing nifedipine |
EP78100854A EP0001247A1 (en) | 1977-09-14 | 1978-09-11 | Pharmaceutical preparation containing nifedipine and a method for producing the same. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11081277A JPS5444034A (en) | 1977-09-14 | 1977-09-14 | Easily absorbable nifedipine composition and anti- stenocardia containing said composition |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5444034A true JPS5444034A (en) | 1979-04-07 |
Family
ID=14545276
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11081277A Pending JPS5444034A (en) | 1977-09-14 | 1977-09-14 | Easily absorbable nifedipine composition and anti- stenocardia containing said composition |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS5444034A (en) |
ZA (1) | ZA783286B (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984003440A1 (en) * | 1981-09-14 | 1984-09-13 | Kanebo Ltd | Long-acting nifedipine preparation |
JPS6429409A (en) * | 1987-06-24 | 1989-01-31 | Air Prod & Chem | Polyvinyl alcohol stabilized vinyl chloride-ethylene-hydroxyethyl acrylate copolymer emulsion |
JP2008504308A (en) * | 2004-06-28 | 2008-02-14 | ライフサイクル ファーマ エー/エス | Porous tablets as carriers for liquid formulations |
-
1977
- 1977-09-14 JP JP11081277A patent/JPS5444034A/en active Pending
-
1978
- 1978-06-08 ZA ZA00783286A patent/ZA783286B/en unknown
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984003440A1 (en) * | 1981-09-14 | 1984-09-13 | Kanebo Ltd | Long-acting nifedipine preparation |
EP0142561A1 (en) * | 1981-09-14 | 1985-05-29 | Kanebo, Ltd. | Long-acting nifedipine preparation |
JPS6429409A (en) * | 1987-06-24 | 1989-01-31 | Air Prod & Chem | Polyvinyl alcohol stabilized vinyl chloride-ethylene-hydroxyethyl acrylate copolymer emulsion |
JP2008504308A (en) * | 2004-06-28 | 2008-02-14 | ライフサイクル ファーマ エー/エス | Porous tablets as carriers for liquid formulations |
Also Published As
Publication number | Publication date |
---|---|
ZA783286B (en) | 1979-06-27 |
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