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JPS54103855A - 1beta, 25-dihydroxyvitamin - Google Patents

1beta, 25-dihydroxyvitamin

Info

Publication number
JPS54103855A
JPS54103855A JP740678A JP740678A JPS54103855A JP S54103855 A JPS54103855 A JP S54103855A JP 740678 A JP740678 A JP 740678A JP 740678 A JP740678 A JP 740678A JP S54103855 A JPS54103855 A JP S54103855A
Authority
JP
Japan
Prior art keywords
dihydroxyvitamin
formula
1beta
dihydroxyprovitamin
steriod
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP740678A
Other languages
Japanese (ja)
Other versions
JPS6136510B2 (en
Inventor
Kiyoshige Ochi
Masafumi Fukushima
Isao Matsunaga
Hideki Nakano
Yasuho Nishii
Minoru Shindo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP740678A priority Critical patent/JPS54103855A/en
Publication of JPS54103855A publication Critical patent/JPS54103855A/en
Publication of JPS6136510B2 publication Critical patent/JPS6136510B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:1β, 25-Dihydroxyvitamin of formula I.
USE: Useful as remedies for hypercalcemia having an anti-vitamin D action.
PROCESS: An 1β, 2β-epoxide compound of formula II is reduced by a metal hydride, e.g. lithium aluminum hydride, to give 1β, 25-dihydroxyprovitamin D3, which is irradiated with ultraviolet light to cleave and isomerize the B ring of the steriod, thus forming the objective substance.
COPYRIGHT: (C)1979,JPO&Japio
JP740678A 1978-01-27 1978-01-27 1beta, 25-dihydroxyvitamin Granted JPS54103855A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP740678A JPS54103855A (en) 1978-01-27 1978-01-27 1beta, 25-dihydroxyvitamin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP740678A JPS54103855A (en) 1978-01-27 1978-01-27 1beta, 25-dihydroxyvitamin

Publications (2)

Publication Number Publication Date
JPS54103855A true JPS54103855A (en) 1979-08-15
JPS6136510B2 JPS6136510B2 (en) 1986-08-19

Family

ID=11664982

Family Applications (1)

Application Number Title Priority Date Filing Date
JP740678A Granted JPS54103855A (en) 1978-01-27 1978-01-27 1beta, 25-dihydroxyvitamin

Country Status (1)

Country Link
JP (1) JPS54103855A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250523A (en) * 1988-04-29 1993-10-05 Wisconsin Alumni Research Foundation Side chain unsaturated 1α-hydroxyvitanim D homologs
JP2008241306A (en) * 2007-03-26 2008-10-09 Jtekt Corp Device and method for measuring moving distance of rolling body,

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697559A (en) * 1971-02-25 1972-10-10 Wisconsin Alumni Res Found 1,25-dihydroxycholecalciferol
JPS51100056A (en) * 1975-02-28 1976-09-03 Chugai Pharmaceutical Co Ltd 1 arufua 255 jihidorokishikorekarushifuerooruno seiho

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697559A (en) * 1971-02-25 1972-10-10 Wisconsin Alumni Res Found 1,25-dihydroxycholecalciferol
JPS51100056A (en) * 1975-02-28 1976-09-03 Chugai Pharmaceutical Co Ltd 1 arufua 255 jihidorokishikorekarushifuerooruno seiho

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250523A (en) * 1988-04-29 1993-10-05 Wisconsin Alumni Research Foundation Side chain unsaturated 1α-hydroxyvitanim D homologs
JP2008241306A (en) * 2007-03-26 2008-10-09 Jtekt Corp Device and method for measuring moving distance of rolling body,

Also Published As

Publication number Publication date
JPS6136510B2 (en) 1986-08-19

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