JPH0394780A - Treating device - Google Patents

Abstract

PURPOSE:To surely and easily treat a desired section with a simple structure by providing a semiconductor material having a photocatalytic effect in at least a part on the outside surface of a chemical luminous body consisting of a chemical light emitting agent. CONSTITUTION:The chemical luminous body 2 is detained in the malignant tumor, for example, cancer tissue 9, generated on the inner side of the inlet part 8 of the uterus 7 of a patient in the state in which the semiconductor electrode layer 6 applied on the surface of the chemical luminous body 2 is held in contact with the cancer tissue 9 when the chemical luminous body 2 is inserted into the above-mentioned inlet part 8. An oxidation reaction takes place on the semiconductor electrode layer 6 when the chemical luminous body 2 emits light for a specified period of time and the illumination light falls onto the semiconductor electrode layer 6 in such a manner. The cancer tissue 9 is then killed by the photocatalytic effect. The light emission of the chemical luminous body 2 ends upon lapse of the specified period of time. The chemical luminous body 2 is pulled to the outside of the body by holding yarn 3 after the treatment ends.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Application Field] The present invention relates to a treatment device that is inserted into a living body to treat an affected part of the living body.

[Prior Art] Recently, photoelectrochemical therapy has been known as a method for treating malignant IIlg4 such as cancer. This is an application of the strong reactivity of the photo-excited semiconductor surface to the killing effect on cancer cells, and experiments have shown that it has a remarkable effect on killing cancer cells.

Now, to explain the principle of the photochemical reaction of semiconductor particles, as shown in Figure 6, there is a type of photochemical reaction. When a conductor is exposed to light, electrons in the valence band are excited into the conductor by photoexcitation, and holes are created in the valence band. If these electrons and holes do not recombine, they can be used for redox reactions. In other words, electrons excited in a conductor have higher energy than electrons in the valence band by the amount of the band gap, so they have a stronger reducing power, and holes in the valence band have a higher electron affinity than empty levels in the conductor by the amount of the band gap. Because it is large, it has oxidizing ability. Titanium oxide (hereinafter referred to as T) is a semiconductor with strong oxidizing and reducing powers.
iO■) is known, and when platinum (hereinafter referred to as pt) is supported on the semiconductor fine particles of Tie2, Tt
It is also known that the photocatalytic ability of 02 is significantly increased.

In a photocatalytic system in which T i O 2 powder containing pt is suspended in a solution, various reactions proceed as a semiconductor is photoexcited, similar to a photochemical cell. This photoexcitation occurs when light with a wavelength shorter than the wavelength corresponding to the band gap of the semiconductor (415 nm in the case of TiO2) is irradiated, and the photoexcited TiO2 surface has a very strong oxidizing power, and it can be oxidized and decomposed.

In addition, the smaller the particle size of the semiconductor particles, the higher the reaction activity (in the case of TiO2, the maximum reaction activity is 0.2 μm or less), and the larger the number of semiconductor particles, the greater the amount of light. The effect is large.

For example, the technology for sterilizing and killing malignant tumors by utilizing the reaction caused by photoexcitation of semiconductors was developed in Japanese Patent Application Laid-open No. 62
-87526 and Japanese Unexamined Patent Publication No. 63-1.77849, particularly the latter, in which a therapeutic probe is introduced into a living body through an insertion channel of an endoscope.
A semiconductor electrode having a photocatalytic effect and a platinum electrode are punctured into a cancer site, and the surface of the semiconductor electrode is irradiated with laser light emitted from the tip of the therapeutic probe. When the semiconductor electrode is irradiated with laser light, an oxidation reaction occurs on the semiconductor electrode, and a reduction reaction occurs on the platinum electrode. Since there is a cancerous site between the two electrodes,
The reaction occurs when water is removed, and oxygen is generated on the semiconductor electrode and moisture is generated on the platinum electrode, that is, a photocatalytic effect occurs.

[Problems to be Solved by the Invention] However, the above-mentioned treatment device introduces a therapeutic probe into a living body through an insertion channel of an endoscope, and uses a semiconductor electrode and a platinum electrode that have a photocatalytic effect to target cancer tissue or the like. The site is punctured, and the surface of the semiconductor electrode is irradiated with laser light emitted from the tip of the therapeutic probe.

Therefore, there is a problem that the electrode and the light irradiation part are separate, and the diameter becomes large, which limits the treatment area in the human body.

The present invention has been made with attention to the above-mentioned problems, and its purpose is to have a simple structure, to reliably reach the target area, and to
Moreover, it is an object of the present invention to provide a treatment device that can perform treatment easily.

[Means and Effects for Solving the Problems] In order to solve the above problems, the treatment device of the present invention includes a method in which a semiconductor material having a photocatalytic effect is provided on at least a part of the outer surface of a chemiluminescent substance made of a chemiluminescent agent. That's true.

The light emitted from the chemiluminescent material causes an oxidation reaction in the semiconductor material, killing the malignant tumor.

[Example code] Hereinafter, each embodiment of the present invention will be described based on the drawings.

FIGS. 1 and 2 show a first embodiment, where 1 is a treatment device. This treatment device 1 has a capsule-shaped chemiluminescent body 2 inserted into a body cavity, and a thread 3 is connected to this chemiluminescent body 2. The chemiluminescent body 2 is formed from a bag body 4 made of a flexible light-transmitting polymer film and a chemiluminescent agent 5 filled in the bag body 4.

This chemiluminescent agent 5 is, for example, TRYLON of the United States.
Cyalum manufactured by ASSOCIATES-LTD (
Cya l uII1 (trade name) is a flexible bag containing a luminescent agent. When the bag is folded and shaken, the luminescent agent inside emits light and the entire bag emits light. The light emission time varies depending on the size, but is about several minutes to several hours.

A part of the outer peripheral surface of the chemiluminescent body 2, this? In this embodiment, a semiconductor electrode layer 6 made of T i 0 2 as a semiconductor material having a photocatalytic effect is provided except on the base end side. This semiconductor electrode layer 6 is obtained by coating the surface of the chemiluminescent material 2 with TiO2.

When using this treatment device 1, the chemiluminescent material 2 is folded and shaken outside the body. When the chemiluminescent material 2 is shaken and the chemiluminescent agent 5 inside emits light, light passes through the bag 4 and the entire bag emits light. Next, as shown in FIG. 2, the chemiluminescent material 2 is inserted into the artificial part 8 of the patient's uterus 7. When the chemiluminescent material 2 is inserted into the artificial part 8 of the uterus 7, the semiconductor electrode layer 6 coated on the surface of the chemiluminescent material 2 is applied to a malignant tumor, for example, a cancerous tissue 9, which has developed inside the entrance part 8. 9 was placed in contact with the patient.

In this manner, when the chemiluminescent body 2 emits light for a certain period of time and illumination light hits the semiconductor electrode layer 6, an oxidation reaction occurs on the semiconductor electrode layer 6, and the cancerous tissue 9 can be killed by the photocatalytic effect. After a certain period of time has elapsed, the chemiluminescent material 2 stops emitting light, and after the treatment is complete, the chemiluminescent material 2 can be pulled out of the body by holding the thread 3.

FIG. 3 shows a second embodiment, and this treatment device 1 includes an elastic rod 10 attached to a capsule-shaped chemiluminescent body 2 inserted into a body cavity.

The chemiluminescent body 2 is basically the same as the first embodiment,
A chemiluminescent agent 5 is housed in a bag 4 made of a flexible, transparent polymer film. And this chemiluminescent body 2
Tie as a semiconductor material that has a photocatalytic effect all around the
A semiconductor electrode layer 6 consisting of 2 is provided.

Therefore, in the case of cancerous tissue 9 that has developed in the esophagus 11 of a living body, the chemiluminescent material 2 is broken and shaken outside the body. When the chemiluminescent material 2 is shaken and the chemiluminescent agent 5 inside emits light, light passes through the bag 4 and the entire bag emits light. Therefore, elastic rod 1
0 is inserted into the esophagus 11 through the oral cavity 12, and the chemiluminescent material 2 is guided to the position of the cancerous tissue 9 by advancing and retracting the elastic rod 10. Further, after the treatment is finished, the chemiluminescent material 2 can be removed from the esophagus 11 by holding the elastic rod 10.

FIGS. 4 and 5 show a third embodiment, in which the treatment device 1 is provided with an insertion guide rod 13 on a capsule-shaped chemiluminescent body 2 to be inserted into a body cavity. The chemiluminescent material 2 is basically the same as that in the first embodiment, and a chemiluminescent agent 5 is housed in a bag body 4 made of a flexible light-transmitting polymer film. Then, Ti as a semiconductor material having a photocatalytic effect is formed around the entire circumference of this chemiluminescent body 2.
A semiconductor electrode layer 6 made of O 2 is provided.

Therefore, in the case of cancerous tissue 9 that has developed in the prostate 14, the hard sheath 16 is inserted into the urethra 15, and the chemiluminescent material 2 is inserted into the prostate 14 by holding the insertion guide rod 13 and using the hard sheath 16 as a guide. . That is, after the chemiluminescent material 2 is folded and shaken so that the chemiluminescent agent 5 inside emits light, the chemiluminescent material 2 is inserted into the rigid sheath 16 by holding the insertion guide rod 13, and then the chemiluminescent material 2 is inserted into the rigid sheath 16 using the insertion guide rod 1.
3 is advanced to guide the chemiluminescent body 2 to the position of the cancerous tissue 9.

Further, after the treatment is completed, the chemiluminescent material 2 can be extracted from the prostate 14 by holding the insertion guide rod 13.

Note that the rigid sheath 16 may be replaced with a guide sheath of a rigid urethroscope.

In the second and third embodiments, the semiconductor electrode layer 10 is made of Tie2 alone, but Tie2 may carry pt. When Tie2 carries pt, the photocatalytic ability of Tie2 increases significantly, and cancer tissue 9 can be effectively killed.

[Effects of the Invention] As explained above, according to the present invention, a semiconductor substance having a photocatalytic effect is provided on at least a part of the outer surface of a chemiluminescent body made of a chemiluminescent agent, and light emitted from the chemiluminescent substance It is possible to provide a treatment device that can kill malignant tumors by causing an oxidation reaction in the semiconductor material, has a simple structure, and can reliably treat the target site.

[Brief explanation of drawings]

1 and 2 show a first embodiment of the present invention, FIG. 1 is a sectional view of the treatment device, FIG. 2 is a sectional view of the device in use, and FIG. 3 is a second embodiment of the present invention. FIG. 5 is a sectional view of the actual device, FIG. 5 is a sectional view of its usage state, and FIG. 6 is a diagram showing the electrochemical reaction process. DESCRIPTION OF SYMBOLS 1... Treatment device, 2... Chemiluminescent material, 6... Semiconductor electrode layer.

Claims (1)

[Claims] A treatment device characterized in that a semiconductor material having a photocatalytic effect is provided on at least a part of the outer surface of a chemiluminescent body made of a chemiluminescent agent.