JPH03292964A - Device for automatically and alternately injecting medicine or contrast medium - Google Patents

Abstract

PURPOSE:To almost simultaneously inject a medicine or the like in a patient at two related places by one injector for a liquid medicine by providing magnet type opening and closing valves to two outflow passages and opening one of the outflow passages while closing the other one of them. CONSTITUTION:When a current is supplied to one set of magnet coils A1, B2 of the valve opening and closing means 2 mounted to the protruding parts 1b, 1b of a pipeline main body 1 for a set time, one opening closing valve 6 opens an outflow passage 4 by the rapid upward movement of an iron piece 6a due to the magnet coil A1 and the other opening and closing valve 7 closes an outflow passage 5 by the rapid downward movement of an iron piece 7a due to the magnet coil B2 and, therefore, the liquid medicine in a pressed injector is injected in one affected region from the opened outflow passage 4 through a sheath. After the set time is elapsed, the supply of a current is changed over to the other set of magnet coils B1, A2 by an electric circuit and the liquid medicine is efficiently injected in the other related affected region from the outflow passage 5 through the sheath.

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] This invention relates to an apparatus for automatic alternate injection of drugs or contrast media, and mainly relates to a device for automatic alternate injection of drugs or contrast media, and mainly relates to a device for the automatic alternate injection of drugs or contrast agents,
It is used to alternately inject drugs or contrast media into different affected areas.

[Conventional technology]

Conventionally, when injecting drugs or contrast agents into the affected area for diagnosis and treatment, a catheter is usually inserted using a puncture needle and guide wire from near the anterior wall of the right femoral artery, 1 to 2 cm caudal to the inguinal ligament. Insert the tip of the catheter (or sheath) into the affected area, connect the proximal end of the catheter to the outflow side of the drug syringe, and inject the drug and/or contrast agent supplied into the syringe into the affected area. was being carried out.

In addition, when examining two related affected areas or lymph vessels, one drug syringe can be used to sequentially inject drugs, contrast agents, or both into the two affected areas or lymph vessels. The drug was either injected or injected almost simultaneously using two drug injectors.

[Problem to be solved by the invention]

In the conventional method of injecting drugs, contrast media, etc. into two related affected areas or lymph vessels using one drug injector, there is a large time lag when injecting the drug, so This made it impossible to perform angiography and other X-ray imaging of two affected areas under the same conditions, which hindered correct diagnosis and treatment.

However, when using two drug injectors, it costs almost twice as much to purchase the drug injectors and the consumables that are discarded after use, compared to using one injector. will require extra space.

This invention was made in view of the above circumstances, and its purpose is to inject drugs, contrast agents, etc. into two related affected areas, lymph vessels, etc. almost simultaneously using a single drug injector. It is an object of the present invention to provide a device for automatic alternate injection of drugs or contrast agents.

[Means to solve the problem]

In order to achieve the above object, in this invention, a conduit main body made of a material that does not dissolve in the drug used, etc. is connected to a catheter or a hose at the distal end side of an inflow passage connected to a syringe. two outflow passages are formed,
An on-off valve operated by a magnetic coil is provided on the two outflow passage sides, and the on-off valve opens one outflow passage and closes the other outflow passage by energizing the magnetic coil, and each outflow passage is closed by switching the energization. is moved in the direction of reversing the opening and closing of the opening and closing, thereby forming an instrument for automatic alternate injection of drugs or contrast media.

When it is desired to inject drugs or contrast media at high speed, the on-off valve in the above-mentioned injection device is made of rod-shaped polycarbonate, with an iron piece enclosed in the upper end and a tapered lower end, and the conduit main body has two parts. Vertical valve storage chambers are formed in the middle of the outflow passage, and the upper end protrudes from the upper surface of the pipe body by a set length and the inner diameter becomes smaller at the lower end. The open/close valve is housed in the pipe body, and two magnet coils are attached and detached in the vertical direction surrounding the two protrusions protruding from the top surface of the pipe main body, and these upper magnet coils teeth,
It is preferable that each of them be connected to an adjacent lower magnet coil.

When a drug or a contrast medium can be injected slowly and the configuration is desired to be simplified, the inflow and outflow passages of the conduit main body are formed by flexible plastic tubes, and the on-off valves are used for the two outflow passages. It is movable to a position where the two outflow passages can be pressed by the magnetic coil located between them, and when the on-off valve is moved by the magnetic coil to the opposite side of each outflow passage facing both ends of the on-off valve. In addition, a member may be provided as a pressure receiver that presses the distal end side of the plastic tube and closes one of the outflow passages.

[For production]

When the proximal ends of catheters or sheaths inserted into the two relevant affected areas are connected to the two outflow passages formed in the conduit body, the opening/closing valve operated by the magnetic coil will open one of the outflow passages. By opening the injector and closing the other outflow passage, by switching the direction of movement of the on-off valve, the drug, contrast medium, etc. supplied into the injector can be injected alternately into two related affected areas.

〔Example〕

Embodiments of the present invention will be described below based on the drawings.

FIGS. 1 to 4 show an embodiment of the present invention, in which a device for alternately injecting medicinal solutions is mainly composed of a conduit main body 1, which is a disposable member, and a valve opening/closing means 2, which is used repeatedly.

The pipe main body 1 is formed with one horizontal inflow passage 3 and two outflow passages 4 and 5 that are branched at the tip thereof. After branching, the direction is once changed vertically downward, and at the lower end, the direction is changed again to the horizontal direction opposite to the inflow passage 3.

The vertical pipes of each outflow passage 4.5 extend upward from the horizontal pipes 4a, 5a that branch at the tip of the inflow passage 3, and extend within protrusions 1b, Ib protruding from the upper surface 1a of the pipe main body 1. has been extended by the length set. Further, the lower end of the vertical pipe has an inner diameter slightly narrowed on the front side where the direction can be changed in the horizontal direction, and a valve storage chamber 4b is formed above it.

5b is formed.

Inside these valve storage chambers 4b, 5b, iron pieces 5a, 7a are enclosed on the upper end side, and a bar-shaped opening/closing valve 6.7 with a tapered lower end is used to connect the iron pieces 5a, 7a to the pipe main body. It is housed so as to be located within the protruding parts 1b, 1b of 1. The on-off valves 6.7 are located in the valve storage chambers 4b and 5b.
It is formed slightly smaller than the diameter of the valve storage chamber 4b.
, when the valve is moved upward in the valve storage chamber 4b.
.

The chemical liquid that has passed through the annular gap between the on-off valve 6.5b and the on-off valve 6.7 is sent through the small diameter portion at the lower end of the valve storage chambers 4b and 5b from the outflow passage 4.5.
7 is moved downward and its lower end taper closes the small diameter portion of the valve storage chambers 4b, 5b, the outflow passage 4.5
The structure is such that no chemical liquid is sent out.

The conduit main body 1 is provided with a connecting portion 8 protruding from a vertical surface and connected in an airtight manner to the distal end side of a chemical liquid syringe (not shown) on the inlet side of the inflow passage 3, as well as connecting portions 8 to each of the outflow passages 4, 5. Connecting portions 9 and 10, which are connected in an airtight manner to the proximal end of a catheter or sheath (not shown), are provided on the outlet side of the tube so as to protrude from the vertical plane, respectively. Reference numeral 11 denotes an engagement holding portion provided on the other vertical surface of the pipe main body 1.

The conduit main body 1 and the on-off valve 6.7 are made of a material that is not dissolved by the drug or contrast agent to be injected, such as polycarbonate, and when injecting the drug solution into the affected area, the drug or the infusion valve 6.7 is made of a material that is not dissolved by the drug or contrast agent to be injected. Care is taken to avoid contamination with substances other than contrast media.

The valve opening/closing means 2 includes two protrusions 1b of the pipe main body 1,
Each protrusion 1b is located at a position corresponding to lb.

Through holes 12.12 through which the A1.1b can be inserted are provided, and two magnet coils A1. A
2 and B, , B2 are provided so as to surround the protrusions 1b, 1b.

Magnet coils Az and B above each through hole 12.12
+ indicates the lower magnet coil B2. of the adjacent through hole 12.12, respectively. A2, and while electricity is supplied to one pair of magnet coils A, B2 for a selected time, the other magnet coils Bl, A
The configuration is such that electricity is not supplied to the second set.

13 is a plate fixed to one end of the valve opening/closing means 2, and the attachment below the valve opening/closing means 2 is a fitting that fits into the engagement holding part 11 of the pipe main body 1 on the plate 13. Union 14
is provided, and the valve opening/closing means 2 is removably attached to the conduit main body 1. For mounting, one magnet coil, for example, A3. After supplying electricity for the set time to the set of B2, the other magnet coil B1. An electric circuit 15 for switching the supply of electricity is provided at A2. Each set of magnet coil (
The switching of the energization to At, B2), (B1.A2) may be performed manually as well as by automatic switching means.

Next, the operation of the above embodiment will be explained.

The proximal ends of catheters or sheaths inserted into two related affected areas are connected to the outflow side connection part 9.10 of the conduit main body 1, and the three-way cock is connected to the inflow side connection part 8. A drug solution syringe equipped with a syringe is connected, and a drug solution containing a drug, a contrast agent, or both of these is supplied while preventing air from entering the syringe.

In this state, the protruding portion 1b of the conduit main body 1.

When one set of magnet coils AI and B2 of the valve opening/closing means 2 attached to valve opening/closing means 1b is energized for a set time, the iron piece 6a of one opening/closing valve 6 is quickly moved upward by the magnet coil A and flows out. The passage 4 is opened, but the iron piece 7a of the other opening/closing valve 7 is quickly moved downward by the magnetic coil B2 to close the outflow passage 5 (see Fig. 4), so that the pressed medicinal liquid in the syringe is released from the passage. is injected into one of the affected areas from the opened outflow passageway 4 through the catheter or sheath.

After the set time has elapsed, the electric circuit 15 connects the other magnet coil B1. When the energization is switched to the group A2, the on-off valve 7 that had previously closed the outflow passage 5
In this case, the iron piece 7a is quickly moved upward by the suction force of the magnet coil B1 to open the outflow passage 5, and conversely, the opening/closing valve 6, which had opened the outflow passage 4, is quickly moved downward by the suction force of the magnet coil A2. to close the outflow passageway 4, the medicinal solution in the syringe is efficiently injected from the outflow passageway 5 through another catheter or sheath to the other related affected area.

Therefore, if the injection device of this embodiment is used, the contrast medium can be injected alternately into two related affected areas using one liquid drug injector, so by combining it with an X-ray device, It is possible to efficiently image angiography at two locations under almost the same conditions in a single imaging process.

Therefore, it is possible to comprehensively judge the two related affected areas and make a correct diagnosis.

Furthermore, based on this diagnosis, by alternately injecting a drug suitable for treatment into two related affected areas, the drug can be evenly distributed to the two related affected areas and effective treatment can be performed.

The injection device of this example can be used for contrast medium imaging and drug therapy in the abdomen (liver, kidney, pancreas, etc.), urinary system, obstetrics and gynecology, and lower extremity areas, as well as in neurosurgery and circulation. It can also be used for X-ray contrast medium imaging in the organ field, lymph vessels, and animal experimental research.

Next, I will explain in some detail about drug treatments for bladder cancer and uterine cancer.

In the case of bladder cancer, one catheter is introduced from the external iliac artery and placed in the left iliac artery, and the other catheter is introduced from the left external iliac artery and placed in the right iliac artery. The patient is then placed in place, and anticancer drugs are alternately injected via an automatic alternate injection device. The arteries of the bladder enter from the left and right and intersect with each other at the peripheral blood vessels, so injecting anticancer drugs from only one side had the disadvantage that the drugs would not evenly spread to the entire bladder cancer, but anticancer drugs from both sides When you inject
This adverse effect can be removed, the anticancer agent can be evenly distributed throughout the bladder cancer, and the therapeutic effect of bladder cancer can be increased.

In the case of uterine cancer, one catheter is introduced from the external iliac artery and placed in the left uterine artery via the left iliac artery, and the other catheter is introduced from the left external iliac artery. and placed in the right uterine artery via the right iliac artery,
Anticancer drugs are alternately injected via an automatic alternate injection device. The arteries of the uterus enter from the left and right and intersect with each other at the peripheral blood vessels, so injecting anticancer drugs from only one side has the disadvantage that the drug does not evenly spread to the entire uterine cancer. By injecting it, this harmful effect can be removed and the treatment effect for uterine cancer can be increased.

In addition, in the case of treatment of ovarian cancer, the anticancer agent may be alternately injected from the left and right ovarian arteries instead of the uterine artery, as an application to the treatment of uterine cancer.

FIGS. 5 and 6 show other embodiments of the invention.

The inflow passage 3 and the outflow passage 4.5 of the pipe main body 1 are made of flexible plastic tubes, for example tubes made of vinyl chloride resin, and between the two outflow passages 4.5, two An on-off valve 17 that is moved toward the two outflow passages 4.5 is provided, and each outflow passage 4,50 facing both ends of the on-off valve 17 is provided.
On the opposite side, pressure receiver members 18 and 19 are provided, and the pipe main body 1, magnet coil C1, and pressure receiver members 18 and 19 are respectively attached to the member 16. .

When the on-off valve 17 is moved toward one of the outflow passages 4 by energizing the magnetic coil C, the pressure receivers on the tip side and the one outflow passage 4 side are the members 18, and the opening/closing valve 17 is moved toward the outflow passage in the direction of movement. 4 to prevent the drug or contrast agent from passing through, and the drug or contrast agent is injected from the other outflow passage 5. Switching the injection of the drug or contrast agent to the magnetic coil C By reversing the direction of energization, the opening/closing valve 17 is moved in the opposite direction.

In the case of the configuration of this embodiment, each outflow passage 4, 5 is alternately pressed by the on-off valve 17 moved by the magnetic coil C and the pressure receiving member 18, 19, so that
The configuration is extremely simple and production costs can be reduced.

〔Effect of the invention〕

Since this invention is configured as described above, it produces the effects described below.

In the device for automatic alternate injection of drugs or contrast agents according to claim 1, two outflow passages are formed on the distal end side of the inflow passage connected to the injector and connected to the catheter or sheath, and the two outflow passages are connected to the catheter or sheath. The device is equipped with an on-off valve that opens one outflow passage and closes the other outflow passage using a magnetic coil, so it is possible to alternately apply drugs or contrast media to two related affected areas using one syringe. It can be injected, reducing the burden on patients and increasing the effectiveness of diagnosis and treatment than ever before.

In particular, in the treatment of various cancers, the peripheral blood vessels of arteries cross each other in the affected area, and injecting anticancer drugs from only one side has the disadvantage of not being able to spread the drug evenly throughout the affected area. By alternately injecting the anticancer drug from both sides of the affected area, the drug can be evenly distributed throughout the area, resulting in excellent effects.

In the device for automatic alternate injection of drugs or contrast media according to claim 2, vertical valve storage chambers are provided in the middle of each of the two outflow passages, and opening/closing valves each having an iron piece sealed in the upper end thereof are stored in these storage chambers. The two on-off valves are moved in opposite directions using two magnetic coils each removably provided on the outside of the upper surface of the pipe main body to open one of the two outflow passages and close the other. In addition to being able to perform alternate injections of drugs or contrast media at high speed, the valve opening/closing means, which is equipped with a plurality of magnetic coils that can be attached to and detached from the tube body, can be used repeatedly. , the cost required for purchasing consumables can be saved.

In the device for automatic alternate injection of drugs or contrast agents according to claim 3, the inflow and outflow passages are formed by flexible plastic tubes, and the two outflow passages are opened and closed by one on-off valve moved by a magnetic coil. In addition, the two pressure receivers provided on the opposite side of each outflow passage facing both ends of the opening/closing valve are alternately operated by members, so the configuration is extremely simple and production costs can be reduced. Can be done.

[Brief explanation of drawings]

Fig. 1 is an exploded perspective view of one embodiment of this emitting device, Fig. 2 is a partially sectional side view of the pipe main body, and Fig. 3 is a plan view of the pipe main body.
FIG. 4 is a sectional front view showing the state in use, FIG. 5 is a perspective view of another embodiment, and FIG. 6 is a sectional plan view showing the state in use. 1...Pipe main body 1a...Top surface 1b...Protrusion part 3...Inflow passage 4.5...Outflow passage 4b, 5b...Valve storage chamber 6, 7. 17... Opening/closing valve 6a, 7a... Iron piece 18.19... Pressure receiving member

Claims (3)

[Claims] (1) The main body of the conduit is made of a material that does not dissolve in the drug used, and two outflow passages are formed at the distal end of the inflow passage connected to the syringe, each connected to a catheter or sheath. On the two outflow passage sides, an on-off valve operated by a magnetic coil is provided, and the on-off valve opens one outflow passage and closes the other outflow passage by energizing the magnetic coil, and by switching the energization, each outflow 1. A device for automatic alternate injection of a drug or a contrast agent, characterized in that the device is moved in a direction that reverses the opening and closing of a passage. (2) The on-off valve is made of rod-shaped polycarbonate, with an iron piece enclosed in the upper end and a tapered lower end, with the pipe main body set in the middle of the two outflow passages, and the upper end side set from the top surface of the pipe main body. Vertical valve storage chambers are formed, each of which protrudes by the same length as shown in FIG. Two magnetic coils are provided on each of the two protrusions surrounding the two protrusions, which can be attached and detached in the vertical direction, and
The device for automatic alternate injection of drugs or contrast agents according to claim 1, wherein each of these upper magnetic coils is connected to an adjacent lower magnetic coil. (3) The inflow and outflow passages of the pipe main body are formed by flexible plastic tubes, and the on-off valve is located between the two outflow passages and can be moved to a position where the two outflow passages can be pressed by a magnetic coil. When the on-off valve is moved by the magnetic coil to the opposite side of each outflow passage facing both ends of the on-off valve,
The device for automatic alternate injection of drugs or contrast media according to claim 1, further comprising a pressure receiving member that presses the distal end side of the plastic tube to close one outflow passage.