JPH02152911A - Control agent against indoor acaridae - Google Patents

Abstract

PURPOSE:To obtain a control agent against indoor acaridae having improved safety and stability without unpleasant odor or skinirritating properties by containing N-normal-butyl carbamic acid 3-iodine-2-propynyl ester. CONSTITUTION:The aimed control agent is obtained by using N-normal-butyl carbamic acid 3-iodine-2-propynyl ester (abbreviated name Bcp) as essential component and carrying with suitable carrier or adding suitable mixing agent. Said control agent is prepared in a shape of oily agent, emulsion, spraying agent, coating agent, hydrating agent, aerosol agent, smoking agent, scattering agent or sustained release preparation, etc. Mixing ratio of Bcp is 0.05-10wt.% as oily agent or aerosol agent, and 0.1-50wt.% as emulsion or hydrating agent.

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Use] The present invention relates to a drug useful for controlling indoor mites.

[Prior Art] With changes in housing structures and lifestyles, the occurrence of indoor mites such as Dermatophagoides mites, Dermatophagoides mites, and Cicada mites has become more frequent, and the damage caused by them has also increased. These indoor mites not only cause itching and discomfort to the human body, but also cause allergic asthma and asthma.

As conventional indoor mite control agents, insecticides that have a proven track record for controlling harmful insects have been repurposed. Known examples of such drugs include organic phosphorus compounds such as fenitrothion, fenthion, and diazinon; carbamate compounds such as bropoxur and NAC; and pyrethroid compounds such as resmethrin, permethrin, and phenotrin.

These drugs are: - diluted with an appropriate solvent and used as a spray, liniment, or injection; - diluted with an appropriate carrier and used as a dispersant; - kneaded into an appropriate resin film or made into microcapsules. It is used in various ways, such as by converting it into a sustained-release preparation.

[Problem to be solved by the invention] However, since mites are morphologically and physiologically different organisms from insects, insecticides that are effective for exterminating insects are not effective at all as agents for controlling mites. It should be considered that they do not necessarily show the same effectiveness. Based on our experience, it is known that some of the insecticides mentioned above can exhibit some degree of mite control effect, but in order to achieve this effect, it is necessary to increase the amount required to control insects. The reality is that much larger amounts of drugs are required. The use of such large amounts of drugs has problems, for example, in terms of safety for the human body when using relatively toxic organic phosphorus compounds and carbamate compounds, and in terms of cost when using expensive pyrethroid compounds.

Furthermore, even when the same drug is used, there are significant differences in its effectiveness depending on the type of tick. For example, it is known that pyrethroid compounds are less effective against mites, and some carbamate compounds and organic phosphorus compounds are less effective against leopard mites.

Furthermore, most of the drugs have a narrow pH range of 5 to 7 in which they exhibit stability, and there is a drawback that long-term efficacy cannot be expected under usage conditions outside this range. Furthermore, when applying the above-mentioned chemicals to textile products, there is a drawback that the heat resistance of the chemicals is insufficient, resulting in large amounts of wear and tear during the treatment process, making it impractical.

be. Moreover, many of the above-mentioned drugs emit unpleasant odors and irritate the skin, making them undesirable for use indoors, where they are closely connected to daily life.

The present invention was made to solve these technical problems, and its purpose is to have no unpleasant odor or skin irritation,
The object of the present invention is to provide a mite control agent that has greatly improved safety and stability and exhibits universally strong efficacy against various mites.

[Means for Solving the Problems] The present invention, which has achieved the above object, is a method for producing indoor mites containing N-normal-butylcarbamic acid 3-iodo-2-propynyl ester as an active ingredient. It is a pest control agent.

[Effect] The present inventors conducted studies from various angles with the aim of developing a mite control agent that is universally effective against various types of mites, has low toxicity to the human body, and has excellent practical physical properties. Layered. As a result, the inventors discovered that a tick control agent that satisfies the above requirements can be realized by using N-normal-butylcarbamic acid 3-iodo-2-propynyl ester (hereinafter abbreviated as BCP) as an active ingredient, and completed the present invention. .

BCP is a white to yellow crystalline powder or granular solid with a slight odor. It is also less toxic, with acute toxicity of LDso being 1470 mg/kg (rats) orally and over 2000 mg/kg (rats and rabbits) dermally.
and has no skin irritation.

Therefore, within the range of the amount of practical use described later, the disadvantages mentioned in the prior art do not occur. Not only that, but it is extremely effective and exhibits a universal acaricidal effect against various types of mites.

BCP is stable in a wide pH range from weak acidity to weak alkalinity, and is hardly damaged by short-term heating at 180° C., and has favorable properties in terms of formulation, processing, maintenance of efficacy, etc.

The mite control agent of the present invention can be used in various forms depending on the purpose of use, by supporting the above-mentioned BCP on a suitable carrier or adding suitable compounding agents. For example, alcohols, ketones, ethers, 1 petroleum.

BCP is dissolved in one or more appropriately selected solvents such as halogenated hydrocarbons to form an oil agent, and an emulsifier is added to form an emulsion, which can be used as a spray or coating agent. It can also be used as a dispersing agent by mixing with talc, clay, etc., or as a hydrating agent, aerosol agent, or smoking agent by adding an appropriate auxiliary agent. Other various forms include ■Kneading into synthetic resin sheets, ■Kneading into latex and kneading into backing materials such as carpets to exert a sustained release effect, ■Impregnating Ta fibers, and ■Adhering with adhesives. Can be used in

When using the mite control agent of the present invention, other indoor mite control agents, repellents, anti-irritants, fragrances, fungicides,
A fungicide or the like may be used in combination as appropriate.

The blending ratio (practical usage amount) of BCP may be determined as appropriate depending on the dosage form, application method, application location, etc., but in the form of oil or aerosol, it is 0.05 to 10! In the form of an emulsion or a wettable powder, it is preferably about 0.1% to 50% by weight, and the common amount is, for example, when used by adhering to fibers, 0.01% to 50% by weight for raw cotton. It is preferable to contain about 5% by weight (more preferably 0.05% by weight).
~1.0% by weight), 0 for cloth (including non-woven fabrics) and paper,
Approximately 05 to 10 g/m2 is preferable (more preferably 0
．． 1-5 g/m2). Furthermore, when it is mixed into a carpet backing material, it may be used in an amount of about 0.5 to 10% by weight.

Hereinafter, the present invention will be explained in more detail with reference to examples, but the following examples are not intended to limit the present invention.
Any design changes for the purposes described below are included within the technical scope of the present invention.

[Example] Example 1 Various drugs shown in Table 1 below were adjusted to o, IW/V%.
Acetone solution and 200m raw polyester long fiber cotton
0.1 ml, 0.2 ml or 0.4 ml in g
After uniformly impregnating and drying, specimens were prepared in which various chemicals were attached in an amount of 0.05°, 0.1 or 0.2% by weight based on the weight of the raw cotton.

This specimen has a height of 4 cm, a diameter of 1.8 cm, and a capacity of 5 m.
On the other hand, 50 mg of a medium containing about 30 of either P. leopard mites, P. elegans mites, or P. elegans was prepared and placed in the screw tube, and the mortality rate after 48 hours was examined. The average value of the two test results is also listed in Table 1.

Example 2 The amount of BCPSfi is 15 parts xylene! 6 parts by weight of a mixture of polyoxyethylene nonylphenyl ether and dodecylbenzenesulfonic acid calcium salt (emulsifier) was added thereto, and further dissolved in 74 parts by weight of kerosene to prepare the emulsion of the present invention.

As a comparative example, an emulsion was also prepared in the same manner as above except that fenthion (5 parts by weight) was used instead of BCP. Also xylene as a blank.

A mixture of emulsifier and kerosene only was also prepared.

Each of these emulsions was diluted 10 times with water and 10x10 (c
The high-quality Japanese paper of ab) was sprayed and dried. The amount of BCP deposited at this time was 2501 g/m2.

Approximately 30 Kona leopard mites per sheet of Japanese paper by Nikole et al.
When the heads were released and the mortality rate 48 hours later was investigated, the results shown in Table 2 below were obtained.

Table 2 As a result, the results shown in Table 3 below were obtained.

Table 3 Example 3 0 g of BCPl was dissolved in 5 g of xylene, and kerosene was added thereto to prepare a 100 ml oil solution. As a comparative example, B
An oil solution was prepared in exactly the same manner as above except that 1.0 g of fenitrothion or resmethrin was used instead of CP. A mixture of only xylene and kerosene was also prepared as a blank.

A 10 x 10 (cm) acrylic non-woven fabric was impregnated with each of these oils at a rate of 50 m1/m2, and after being thoroughly air-dried, approximately 20 minamimites per non-woven fabric were impregnated with each of these oils.
The heads were released and the mortality rate was investigated 48 hours later [Effects of the Invention] As described above, according to the present invention, it is possible to improve all the drawbacks of conventional drugs such as odor, irritation, safety, and stability. We were able to create a mite control agent that is universally effective against various types of mites.

Claims (1)

[Claims] An indoor mite control agent characterized by containing N-normal-butylcarbamic acid 3-iodo-2-propynyl ester as an active ingredient.