JPH01243970A - Artificial high-density liquid diet - Google Patents

Abstract

PURPOSE:To obtain the title liquid diet containing protein, dextrin, lipid containing a middle-chain fatty acid triglyceride, vitamin and mineral as main ingredients, having a specific particle size and granular form, containing CaCO3 as Ca salt in the mineral and capable of using for supplying nutrition to a patient before or after operation. CONSTITUTION:The aimed artificial high-density liquid diet being <=20wt.% in ratio of <=0.1mm particle size, having granular form and using calcium carbonate as a calcium salt in the mineral in the liquid diet containing protein (e.g., casein, soybean protein or egg protein), dextrin, lipid containing 6-12C middle- chain fatty acid triglyceride, vitamin and mineral as main ingredients. Furthermore, the above-mentioned main ingredients are preferably blended at ratio of 3-30% lipid, 10-40% protein and 50-80% dextrin.

Description

DETAILED DESCRIPTION OF THE INVENTION (Field of Industrial Application) The present invention relates to an artificially concentrated liquid diet used for nutritional supplementation to patients before and after surgery.

(Prior art) Artificially concentrated liquid foods are made by mixing various nutrients such as natural foods and natural foods decomposed to various degrees.
It is formulated into a high calorie and nutritionally balanced composition. These foods are used when nutritional support is required before and early after surgery, and when long-term nutritional management is required.

Artificially concentrated liquid foods currently used for this purpose include:
Powder and liquid products are commercially available.

Powdered products must be prepared by dissolving them in hot water in order to be administered to patients, and in such cases, the product contains a large amount of minerals, so the solubility of proteins is extremely poor.
It was necessary to dissolve it using a juice mixer or the like.

Therefore, studies are being carried out to increase the solubility of powdered products by granulating them (Special Publication No. 53006/1983;
No. 53007).

(Problem B to be solved by the invention) Powdered artificially concentrated liquid foods include powdered foods and granulated foods. Powdered products require the use of a juice mixer to sufficiently dissolve them, which sterilizes these containers, which is very time-consuming.

Granules have improved solubility than powders and can be dissolved with a whipper, but
There was a problem in that it took a very long time to dissolve. In addition, undissolved lumps remained, which was thought to cause tube clogging.

Furthermore, the proteins used in artificially concentrated liquid foods are formulated taking into consideration the balance of essential amino acids, and mainly include casein, soybean protein, and egg protein. Soybean protein and egg protein become insoluble due to heat denaturation, and when incorporated into a powdered artificially concentrated liquid food, the solubility of the powder deteriorates, so they are not used. Currently, there are no granular products that use these proteins.

(Means for Solving the Problems) The present invention is intended to solve these problems, and contains protein, dextrin, lipids containing medium-chain fatty acid triglycerides with 6 to 12 carbon atoms, vitamins, and minerals as main components. The artificial concentrated liquid food is characterized in that it is in the form of granules with a particle size ratio of 0.1) or less of 20% by weight or less, and the calcium salt in the mineral is calcium carbonate.

The artificial concentrated liquid food of the present invention is in the form of granules in which the proportion of particles with a diameter of 0.1 mm or less is 20% by weight or less. Particle size is 0.1
When it is less than mm, it becomes powdery, but the proportion of this substance is 2
If it is less than 0% by weight, it can maintain a granular shape as a whole, but if it is more than 20% by weight, it becomes powdery rather than granular, which is not desirable from the viewpoint of solubility.

The main components of the present invention are proteins, dextrins, lipids, vitamins and minerals.

Proteins that are easy to digest and have high nutritional value are used, but considering the balance of essential amino acids, mainly casein,
Soybean protein, egg protein, and their enzymatically decomposed products are used. In addition, fish protein, meat protein, gelatin, etc. can also be used.

As the dextrin, a hydrolyzate using corn starch, tapioca starch, potato starch, etc. is used, and one having a DE value (degree of hydrolysis) of 10 to 30 is used.

The lipid contains medium-chain fatty acid triglyceride having 6 to 2 carbon atoms, and a combination thereof with a processed fat or oil such as soybean oil, corn oil, rapeseed oil, coconut oil, lard, beef tallow, or fish oil is suitable. The medium chain fatty acid triglyceride in the present invention is a glycerin ester of a medium chain fatty acid having 6 to 12 carbons, mainly 8 carbon atoms. When using an oil or fat containing medium-chain fatty acid triglyceride, the powder has better solubility in water than when other oils or fats are used.

In addition, medium-chain fatty acid triglycerides are absorbed quickly in the body.
When artificially concentrated liquid food using this is administered to a patient,
Diarrhea can be prevented.

The amount of medium chain fatty acid triglyceride used in the present invention is 5 to
50% by weight is appropriate; if it is less than 5% by weight, the above effects will not be observed, and if it exceeds 50% by weight, it will result in the reduction of other necessary fats and oils, such as fats and oils containing essential amino acids, which is not preferable.

The blending ratio of lipid, protein, and dextrin in the present invention is 3 to 30% by weight of lipid per solid content of the nutritional composition;
Protein is 10-40% by weight, dextrin is 50-80%
It is about % by weight.

In addition, minerals necessary for nutrition are used, including sodium,
Salts such as potassium, calcium, iron, and magnesium are added in nutritionally necessary amounts as appropriate.

Among these, calcium carbonate is used as the calcium salt, and powdered artificial concentrated liquid foods containing other calcium salts have poor solubility and cannot be used.

Further, vitamins are added in nutritionally necessary amounts as appropriate, and emulsifiers, emulsion stabilizers, fruit juices, and flavorings are added as necessary.

The artificially concentrated liquid food of the present invention is prepared by dissolving the compound in water, emulsifying it, drying it by spray drying or the like to form a powder, and then granulating it using a suitable granulation means. Granulation can be carried out by a known method, such as a fluidized bed granulation method.

When the product of the present invention is used, it is dissolved in water or hot water at a solid concentration of 5 to 40% by weight, usually about 20 to 25%, and is administered orally or by tube into the stomach, intestines, etc. It can be easily and stably supplied to the digestive organs.

(Effects of the Invention) The granular artificially concentrated liquid food of the present invention has extremely good solubility in hot water, so there is no need to use a special dissolving device such as a juice mixer, and it can be prepared manually using a whipper. By stirring with , it is possible to dissolve in a shorter time than conventionally.

Furthermore, in the present invention, soybean protein and egg protein can be used without deterioration in solubility, and therefore, the essential amino acid balance is good, and sufficient nutritional support can be provided to the patient.

Since the present invention contains medium-chain fatty acid triglycerides, the powder has better solubility in water than when other fats and oils are used. Furthermore, medium chain fatty acid triglycerides have 1 carbon number.
Since it has the property of being absorbed into the human body faster than triglycerides with long chain fatty acids of 4 or more, the products of the present invention containing this can prevent diarrhea caused by poor fat metabolism.

(Examples) Next, the present invention will be explained in detail using Examples, Comparative Examples, and Test Examples. Hereinafter, percentages are based on weight.

Example 1 Dissolve 50g of disodium phosphate in 15kg of water,
In this liquid, 1.1 kg of sodium caseinate, 700 g of soybean protein, 200 g of whole egg powder, and 6.5 kg of dextrin were dissolved. On the other hand, medium-chain fatty acid triglycerides mainly having 8 carbon atoms (fatty acid composition C8: 85%, C+
o: 15%) 300g, 1) 20g of polyglycerin fatty acid ester was dissolved in an oil mixed with 80g of soybean oil, and this blended lipid was blended into the above mixed liquid and emulsified. This liquid was spray-dried to obtain about 10 kg of powder product. The vitamins and minerals shown in Table 1 were mixed into this powder product.

Further, this powder product was placed in a fluidized bed granulator, and granulation was performed after spraying purified water into the fluidized bed.

This granulated product had a component ratio of 1% having a particle size of 0.1 mm or less. This can be dissolved in warm water to make a 25% aqueous solution and used as an artificial concentrated liquid food. When this aqueous solution was left in a cold place for 24 hours, it showed good emulsion stability without any separation of components.

Table 1 Addition amount per 1 kg of powder product ○ 300ml (mg) Vitamin A (180
0001U/g) 25.0 Vitamin B1 Thiamine hydrochloride 2.5 Vitamin B2 Riboflavin phosphate 2.5 Vitamin B6 Pyridoxine hydrochloride 10.0 Vitamin CI25.0 Vitamin D 3 (2000001U/g)
1.3 Vitamin E (20%) 375
．． 0 Nicotinamide 62.5 Calcium pantothenate 25.0 Folic acid
10.00m fresh hot dish
(g) Sodium chloride 3.
Potassium trichloride 3.5 Calcium carbonate 3.7 Iron ammonium citrate 0.05 Magnesium sulfate
3.5 Example 2 A granulated product was obtained by processing according to Example 1, except that a partially decomposed product of soybean protein (decomposition rate: 40%) was used instead of 700 g of soybean protein in Example 1. This granulated product had a component ratio of particles with a particle size of 0.1 mm or less at 18%. This can be used as an artificially concentrated liquid food by dissolving it in warm water, and when this liquid was left in a cold place for 24 hours, it showed good emulsion stability.

Comparative Example 1 In place of calcium carbonate in Example 1, 1). 3
A granulated product was obtained by processing according to Example 1, except that 1 g of calcium lactate was used. This granulated product is 0.1m
The proportion of components with particle diameters of m or less was 1%.

Comparative Example 2 A granulated product was obtained in the same manner as in Example 1, except that 300 g of lard was used instead of the medium-chain fatty acid triglyceride in Example 1. This granulated product is 0.1mm
The component proportions of the following particle diameters were 5%.

Comparative Example 3 A granulated product was obtained according to Example 1. This granulated product had a component ratio of 25% having a particle size of 0.1 mm or less.

Comparative Example 4 In place of soybean protein and whole egg powder in Example 1, 2
．． Using 4kg of skim milk powder, 6.5kg of dextrin
The weight was reduced from 5.2 kg to 5.2 kg. Furthermore, 7.7 g of calcium glycerophosphate was used instead of calcium carbonate, and the process was otherwise carried out in accordance with Example 1 to obtain a granulated product. This granulated product had a component ratio of 2% having a particle size of 0.1 mm or less.

Solubility tests were conducted on deentanglement wipe Examples 1 to 2, Comparative Examples 1 to 4, and commercially available products.
0 was added and dissolved by hand stirring with a whipper, and the dry weight of the undissolved components was measured. The results are shown in Figure 1.

From the results shown in FIG. 1, it is clear that the product of the present invention has significantly superior solubility. When this liquid was administered through a tube, nutrition could be supplied without clogging the tube.

[Brief explanation of the drawing]

・Figure 1 shows Example 1 (0), Example 2 (・),
Comparative example 1 (b), comparative example 2 (■), comparative example 3 (△)
, Comparative Example 4 (M) and commercial product (X), 400g of 50℃ warm water was added to each 100g sample, and stirred and dissolved by hand using a whipper. Stirring time (seconds) and insoluble components The relationship between dry weight (g) and dry weight (g) is shown.

Claims (1)

[Claims] (1) In an artificially concentrated liquid food whose main components are protein, dextrin, lipids containing medium-chain fatty acid triglycerides with 6 to 12 carbon atoms, vitamins, and minerals, 0.1 mm
It is in the form of granules with a particle size ratio of 20% by weight or less,
An artificially concentrated liquid food characterized in that the calcium salt in the mineral is calcium carbonate.