JPH08119855A - Plaster - Google Patents

Abstract

PURPOSE: To obtain a plaster capable of imparting a corset effect to a body and good in the use touch by using the laminate of a synthetic resin foam to woven or nonwoven fabric as a support, and subsequently forming an adhesive agent layer on the woven or nonwoven fabric of the support. CONSTITUTION: Woven fabric or nonwoven fabric is attached on one side of a synthetic resin foam (e.g. polyethylene foam), and 5-80wt.% of the whole surface area is fused or bonded. The laminate thus produced is used as support. An adhesive agent layer containing an adhesive agent as a main component is formed on the woven or nonwoven fabric side of the support to prepare the plaster. The fusion is performed by a method comprising e.g. thermally melting the foam and subsequently laminating the woven fabric or nonwoven fabric to the melted surface, and the formation of the adhesive agent is performed e.g. by a solvent-coating method. The plaster exhibits a corset effect, when the plaster is adhered to a diseased site in the state wherein the peelable foam layer is attached. When the foam layer is peeled, the left plaster can be adhered to a site requiring elasticity, such as a shoulder or joint, without giving a bulky touch or a feeling of physical disorder.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a patch.

[0002]

2. Description of the Related Art Conventionally, by using a woven cloth, a non-woven cloth, a foam or the like as a support for a patch provided with an adhesive layer containing a drug, a support feeling, that is, a corset effect is obtained. The method of giving is done. For example, there is disclosed a medical patch having a corset effect in which a pressure-sensitive adhesive layer containing a medicinal component is provided on a support obtained by laminating a nonwoven fabric on a foam (Japanese Patent Laid-Open No. 4-308527).

However, such a patch easily exerts a corset effect when applied to a specific site disease such as a backache and a sprain, but in other sites such as a shoulder or a joint, a bulky feeling or There was a problem that it was awkward and difficult to apply.

[0004]

SUMMARY OF THE INVENTION The present invention has been made in order to solve the above-mentioned drawbacks, and its purpose is to exhibit a corset effect and to attach it to a shoulder or a joint. An object of the present invention is to provide a patch that does not give a bulky feeling or a feeling of strangeness.

[0005]

[Means for Solving the Problems]

The patch of the present invention has a laminated body of a synthetic resin foam and a woven or non-woven fabric as a support, and an adhesive layer is provided on the woven or non-woven fabric side of the support.

As the support, a laminated body in which a synthetic resin foam and a woven or non-woven fabric are partially fused or adhered is used. As the synthetic resin foam, a foam such as polyethylene, ethylene-vinyl acetate copolymer, polyurethane, polypropylene or polyvinyl chloride is used. The foam may be either a crosslinked type or a non-crosslinked type, and the expansion ratio thereof is preferably 5 to 55 times, more preferably 20 to 30 times. In addition, a pretreatment such as a corona discharge treatment or a primer treatment may be performed on the surface of the foamed material laminated with the woven or non-woven fabric.

The above woven fabrics include cotton, staple fabric, nylon,
Woven cloth of fibers such as rayon can be mentioned, but the weaving method,
The density and denier are not particularly limited. Examples of the non-woven fabric include fibers made of rayon, cellulose, nylon, polypropylene, polyethylene terephthalate or the like, either alone or as a mixed product. The nonwoven fabric may be felt.

The fibers used in the non-woven fabric may be short fibers or long fibers, and the non-woven fabric has a basis weight of 15 to 120 g / m.
² is preferable, and more preferably 40 to 70 g / m ² . The thickness of the non-woven fabric is preferably 0.1 to 0.3 mm.

Lamination of the synthetic resin foam and a woven or non-woven fabric is carried out by partial fusion or adhesion. Examples of partial fusion or adhesion include spot-shaped, mesh-shaped, and stripe-shaped fusion or adhesion.

As a method of fusion bonding, heating is performed by applying a flame to the foam side, and when the surface is melted, a woven fabric or a non-woven fabric is laminated on the fusion surface, or between the foam and the woven fabric or the non-woven fabric. A method of inserting a heat-sealing layer such as a polyethylene sheet and stacking the layers and then heating and melting the woven or non-woven fabric side can be mentioned. The adhesive used for adhesion is not particularly limited as long as it can adhere the foam and the woven or non-woven fabric, and examples thereof include an adhesive used in an adhesive layer described below.

The above partial fusion or adhesive strength does not need to be so strong, but is stronger than the adhesive force of the pressure-sensitive adhesive layer to the skin, and can be peeled without breaking the woven or non-woven fabric when peeled by hand. The strength of

In order to obtain the above fusion or adhesive strength,
The fused or bonded area is limited to 5-80% of the total area, preferably 20-50%.

A pressure-sensitive adhesive layer containing a pressure-sensitive adhesive as a main component is formed on the woven or non-woven fabric side of the support.

As the above-mentioned pressure-sensitive adhesive, a lipophilic pressure-sensitive adhesive and a hydrophilic pressure-sensitive adhesive are preferably used.

Examples of the lipophilic pressure-sensitive adhesives include those containing styrene-isoprene-styrene block copolymer, polyacrylic acid ester-based polymer, natural rubber and various synthetic rubbers as main components. In addition, the lipophilic adhesive,
As required, tackifiers such as terpene-based resins, alicyclic-based synthetic resins, and rosin-based synthetic resins; softening agents such as liquid paraffin, fatty acid esters, polybutene; fillers such as titanium oxide and zinc oxide; BHT, etc. Anti-aging agents and the like may be added.

Examples of the hydrophilic adhesive include natural water-soluble polymers such as sodium alginate, gelatin, corn starch, tragacanth gum, and casein; methyl cellulose, carboxymethyl cellulose, polyvinyl alcohol, sodium polyacrylate, methoxyethylene-
Examples thereof include synthetic or semi-synthetic hydrophilic polymers such as maleic anhydride copolymers and polyvinyl ethers.

If necessary, the hydrophilic adhesive may include humectants such as glycerin and propylene glycol; swelling agents such as water; organic solvents such as acetone and methyl ethyl ketone; kaolin, bentonite, aluminum sulfate, zinc oxide and the like. Fillers and the like may be added.

A drug may be mixed in the pressure-sensitive adhesive layer. Examples of the drug include salicylates such as glycol salicylate and methyl salicylate; capsicum extract, nonyl vanillamide, camphor, topical oil, menthol, thymol, vitamin E and other external preparations; sancin,
Herbal medicines such as yellow oak, chamomile, aloe and arnica; anti-inflammatory and analgesic agents such as indomethacin, ketoprofen and chlorbiprofen.

The content of the drug in the adhesive layer is
0.1 to 1.5% by weight is preferable.

Examples of the method for forming the pressure-sensitive adhesive layer include hot melt coating method, solvent coating method, calender coating method and the like. In the solvent coating method, the pressure-sensitive adhesive is diluted with a suitable solvent as necessary, and is made into a solution at a warmed state or at room temperature, and a drug is further added if necessary to uniformly mix the pressure-sensitive adhesive composition. After the preparation of the adhesive composition, the adhesive composition is applied to the woven or non-woven fabric side of the support and dried to remove the solvent to form an adhesive layer on the support to prepare a patch. You can Further, this solution may be coated on a release paper and dried, and then transferred to a support to form an adhesive layer. Further, this release paper may be stuck until the time of use for the purpose of protecting the pressure-sensitive adhesive layer.

The pressure-sensitive adhesive layer does not necessarily have to be formed on the entire surface of the support, and may be formed partially or intermittently. The thickness of the adhesive layer is 100 to 350 μm.
m is preferred.

A patch (product) can be obtained by cutting the above patch into a predetermined shape and packaging it. The size and shape of the product are not particularly limited, but in order to exert the corset effect, it is 50 to 150 mm × 150 to
A 300 mm rectangle is preferred.

[0024]

The patch of the present invention can impart a corset effect by using a laminate of a synthetic resin foam and a woven or non-woven fabric as a support, and peels the synthetic resin foam from the support. As a result, the user does not feel bulky or uncomfortable even if it is attached to a region such as a joint that requires elasticity.

[0025]

Next, embodiments of the present invention will be described. (Example 1) Fusion of striped polyethylene shown in FIG. 2 on one surface of a rayon / polyethylene terephthalate mixed nonwoven fabric (mixed ratio 80/20, thickness 0.25 mm, basis weight 70 g / m ² , long fiber nonwoven fabric) A layer 3 (50% of the total area) is provided on which the crosslinked polyethylene foam 22 shown in FIG. 1 is provided.
(Sekisui Chemical Co., Ltd. "Sekisui Softlon IF3002
5 ", foaming ratio 30 times, thickness 2.5 mm, cross-linked type)
Were piled up and heated from the side of the nonwoven fabric 21 to form a support.

100 parts by weight of styrene-isoprene-styrene block copolymer, alicyclic saturated hydrocarbon resin 120
Parts by weight, 20 parts by weight of isopropyl myristate, 20 parts by weight of liquid paraffin, 5 parts by weight of titanium oxide and 5 parts by weight of dibutylhydroxytoluene are stirred and mixed at 150 ° C. under nitrogen substitution to prepare an adhesive, and then the adhesive is prepared. 1 part by weight of 1-menthol was added to 99 parts by weight of the mixture, and the mixture was purged with nitrogen.
The mixture was stirred and mixed at 0 ° C. to obtain an adhesive composition.

A polyethylene terephthalate film (0.035 μm) obtained by subjecting the above pressure-sensitive adhesive composition to a silicone release treatment.
(m thickness) of the silicon release-treated surface was uniformly applied so as to have a thickness of 0.2 mm, and then cooled and solidified to obtain a pressure-sensitive adhesive layer. Next, as shown in FIG. 1, this pressure-sensitive adhesive layer 1 was transferred and brought into close contact with the non-woven fabric 21 side of the support 2 and then punched out to 100 × 215 mm to obtain a patch.

Example 2 Foam 22 similar to Example 1
Adhesive 4 (“Scotch” manufactured by 3M Co., for fibers) was applied to one surface of the above in a spotted manner with a thickness of 0.2 mm as shown in FIG. 3 (application area is 5% of the whole), and then a polyester polyolefin nonwoven fabric ( A patch was prepared in the same manner as in Example 1 except that "ED6" manufactured by Nippon Vilene Co., Ltd., thickness 0.25 mm, basis weight 60 g / m ² ) was laminated to form a support.

(Example 3) Foam 22 similar to Example 1
Adhesive 4 (“Scotch” manufactured by 3M Co., for fibers) is applied to one side of the above in a mesh-like manner with a thickness of 0.2 mm as shown in FIG. 4 (application area is 5% of the whole), and then a polyester polyolefin nonwoven fabric ( "ED6" manufactured by Japan Vilene Co., Ltd.) was laminated to obtain a support.

After uniformly mixing 100 parts by weight of gelatin, 35 parts by weight of sodium polyacrylate, 7 parts by weight of titanium oxide, 30 parts by weight of glycerin and 30 parts by weight of purified water to prepare an adhesive, 99 parts by weight of this adhesive To 1 part by weight, 1 part by weight of l-menthol was added and mixed with stirring to obtain an adhesive composition.

A polyethylene terephthalate film (0.035 μm) obtained by subjecting the above pressure-sensitive adhesive composition to a silicone release treatment.
(m thickness) of the silicone release treated surface was uniformly applied so as to have a thickness of 0.25 mm, and then cooled and solidified to obtain an adhesive layer. Next, this pressure-sensitive adhesive layer was transferred and brought into close contact with the non-woven fabric side of the above support, and then punched out to 100 × 215 mm to obtain a patch.

Comparative Example 1 A support was obtained by laminating the rayon / polyethylene terephthalate mixed nonwoven fabric of Example 1 after lightly applying a flame to one side of a foam similar to that of Example 1 to melt the entire surface. A patch was obtained in the same manner as in Example 1.

Comparative Example 2 An adhesive (“Scotch” manufactured by 3M Co., for fibers) was applied over one surface of a foam similar to that of Example 1 to a thickness of 0.2 mm. A patch was obtained in the same manner as in Example 3 except that a support was obtained by laminating a rayon / polyethylene terephthalate mixed nonwoven fabric.

(Comparative Example 3) As shown in FIG. 5, a polyethylene fusion-bonding layer 3 was provided in spots (1% of the total area) on one surface of the rayon / polyethylene terephthalate mixed paper nonwoven fabric 21 of Example 1, and A patch was obtained in the same manner as in Example 3, except that the same foam as in Example 1 was laminated on the above to obtain a support.

(Comparative Example 4) As shown in FIG. 5, a polyethylene fusion-bonding layer 3 was provided in a striped pattern (90% of the total area) on one surface of the rayon / polyethylene terephthalate mixed nonwoven fabric 21 of Example 1. A patch was obtained in the same manner as in Example 3, except that the same foam as in Example 1 was laminated on the above to obtain a support.

With respect to the patches obtained in the above Examples and Comparative Examples, the following evaluations were made and the results are shown in Table 1. (1) Ease of peeling The patch was handed to 10 volunteers one by one, and the layers of the foam and non-woven fabric of the support were peeled off by hand, and the ease of peeling was evaluated according to the following five criteria (points). I got it evaluated. 1 point: very difficult to peel or does not peel off 2 points: difficult to peel off 3 points: neither easy to peel nor hard to peel off 4 points: easy to peel off 5 points: very easy to peel off

(2) Fusing or Adhesive Strength Ten volunteers each apply one patch to the lumbar region for one day, hold the foam part by hand and peel the non-woven fabric and foam from the lumbar region. Whether or not the fusion or the peeling of the adhered portion occurred was evaluated according to the following five-level judgment criteria (score). 1 point: The foam was peeled off on the entire surface and the whole nonwoven fabric remained on the skin 2 points: Most of the foam was peeled off and most of the nonwoven fabric remained on the skin 3 points: A part of the foam was Peeled off and part of the non-woven fabric remained on the skin 4 points: Most of the foam was peeled off and most of the non-woven fabric was peeled off 5 points: No peeling of the foam occurred and the non-woven fabric was completely on the skin Did not remain

(3) Bulkiness and discomfort: 10 volunteers were given 2 patches each, the layers of the non-woven fabric and the foam were peeled off by hand, and then 1 patch was applied to the shoulder for 1 day to give a bulky feeling. Another sheet was attached to the elbow for 1 day, and the discomfort was evaluated according to the following five-level judgment criteria (score). 1 point: Very high 2 points: Moderate 3 points: Neither can be said 4 points: Moderate 5 points: None

Table 1 shows the total scores evaluated by 10 volunteers.

[0040]

[Table 1]

[0041]

The composition of the patch of the present invention is as described above, and when it is applied to the affected area with the peelable foam layer still attached, the corset effect can be exerted. When the layer is peeled off, it can be attached to a region such as a shoulder or joint where elasticity is required without giving a bulky feeling or a strange feeling.

[Brief description of drawings]

FIG. 1 is a schematic cross-sectional view showing a patch of the present invention.

FIG. 2 is a plan view showing a polyethylene fusion-bonding layer provided in a striped manner on one surface of a nonwoven fabric in Example 1.

FIG. 3 is a plan view showing an adhesive applied in spots on one surface of a foam in Example 2.

FIG. 4 is a plan view showing an adhesive applied in a mesh shape on one surface of a foam in Example 3.

FIG. 5 is a plan view showing a polyethylene fusion-bonding layer provided on one surface of a non-woven fabric in spots in Comparative Example 3.

6 is a plan view showing a polyethylene fusion-bonding layer provided in a striped pattern on one surface of a nonwoven fabric in Comparative Example 4. FIG.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Adhesive layer 2 Support 21 Woven or non-woven fabric 22 Foam 3 Fusion layer 4 Adhesive

Claims (1)

[Claims] 1. A woven or non-woven fabric is provided on one side of a synthetic resin foam, and the fusion or adhesion area thereof is 5 to 80% of the total area.
A patch, which comprises a laminate which is partially fused or adhered so that the substrate has a support, and a pressure-sensitive adhesive layer is provided on the woven or nonwoven fabric side of the support.