JPH04217614A - Liquid dentifrice composition - Google Patents

Abstract

PURPOSE:To obtain a liquid dentifrice composition containing abrasives uniformly dispersed in an aqueous medium, having low viscosity and reduced in fluidity change with the lapse of time. CONSTITUTION:A liquid dentifrice containing 5-40% abrasives and having 20-180 poise viscosity at 25 deg.C and 1-60 pascal yield value at 25 deg.C is blended with polyoxyethylenealkyl ether to provide the objective composition.

Description

[Detailed description of the invention]

0001

[Industrial Application Field] The present invention is characterized in that an abrasive is uniformly dispersed in an aqueous medium and has a fluid viscosity (at 25°C) of 20°C.
The present invention relates to a liquid dentifrice composition of ~180 poise, and particularly to a liquid dentifrice composition that exhibits stable fluidity over a long period of time.

0002

[Prior Art and Problems to be Solved by the Invention] Conventionally, various proposals have been made regarding liquid toothpaste (for example,
Special Publication No. 45-36599, Special Publication No. 55-1544
No. 3 Publication, etc.), there are almost no examples of it being put to practical use. This is because when conventional liquid toothpaste is placed on the bristles of a toothbrush, it immediately soaks into the bristles and drips from the toothbrush, resulting in poor usability.

Furthermore, when such conventional liquid toothpaste is stored in a plastic bottle or the like, there is a problem that the fluidity or extrudability is too good and too much flows out when it is placed on a toothbrush.

[0004] For this reason, conventionally toothpaste has been mostly used, and gel toothpaste with a relatively low viscosity (200 to 500 poise) has also been used (Japanese Patent Application Laid-open No. 75412-1983).
, No. 75413), but these toothpastes have excellent dispersibility in the mouth and ease of cleaning the toothbrush after brushing (contrary to conventional toothpastes, the dentifrice tends to remain on the bristles of the toothbrush and is difficult to clean. On the other hand, the use of liquid toothpaste is desirable because rinsing the brush after toothbrushing is easy and hygienic.Therefore, it is desired to solve the above-mentioned poor usability of liquid toothpaste.

[0005] In this case, most conventional liquid toothpastes do not contain abrasives. However, in order to ensure the stain removal power (cleaning power) of liquid toothpaste, it is desirable to incorporate an abrasive into the toothpaste. For this purpose, it is necessary to stably disperse the abrasive in the liquid toothpaste, and conventionally, it has been proposed to use xanthan gum for stable dispersion of the abrasive (Japanese Patent Publication No. 36599/1983). .

However, in order to ensure the cleaning power, the present inventors have found that a certain amount or more, that is, 5 to 40% of the total composition (
It has been found that when an abrasive of % by weight (the same applies hereinafter) is blended, the fluidity of the liquid toothpaste changes and decreases over time. That is, liquid toothpaste is prepared to have a low viscosity, but when an abrasive is added to it, the fluidity decreases over time, and there are cases where the toothpaste stops flowing after long-term storage.

[0007] Therefore, there is a need for a liquid dentifrice that prevents the fluidity of a liquid dentifrice composition containing an abrasive from decreasing over time and that exhibits good fluidity even after long-term storage.

The present invention has been made in response to the above-mentioned needs, and is characterized in that the abrasive is stably dispersed in a low-viscosity aqueous medium, and
Another object of the present invention is to provide a liquid dentifrice composition that prevents changes in fluidity over time and exhibits stable fluidity over a long period of time.

[0009]

[Means and effects for solving the problem] The present inventors have
As a result of intensive studies to achieve the above objectives, we determined that the viscosity of liquid toothpaste containing 5 to 40% abrasives was 20 to 180 poise (at 25 degrees Celsius), and the yield value was 1 to 60 pascals (at 25 degrees Celsius). When polyoxyethylene alkyl ether, especially polyoxyethylene alkyl ether with an added mole of ethylene oxide of 2 to 15, is added, the abrasive can be dispersed stably over time, and the amount of abrasive can be adjusted to It was found that even at 5% to 40%, the decline in fluidity over time is prevented as much as possible, and even after long-term storage at high temperatures, it shows good fluidity and has excellent fluidity stability. .

[0010] Furthermore, this liquid toothpaste is easy to put on the toothbrush, and does not immediately soak into the flocked areas when placed on the toothbrush, so that the toothpaste is not brushed until the user puts the toothpaste on the toothbrush, puts it in the mouth, and uses it. is well retained on the bristle part of the toothbrush, and has good extrusion properties when extruded from a plastic bottle, etc., and has excellent usability, and has good dispersibility in the mouth as a liquid toothpaste. It was also found that the cleaning properties are excellent.

Therefore, the present invention provides an aqueous medium containing 5 to 40% of the abrasive, a viscosity at 25°C of 20 to 180 poise, and a yield value of 1 to 60 Pascal at 25°C. To provide a liquid dentifrice composition characterized in that a polyoxyethylene alkyl ether is blended into the liquid dentifrice composition.

[0012] The present invention will be described in more detail below.The liquid dentifrice composition of the present invention is one in which the abrasive is stably and uniformly dispersed in a low-viscosity aqueous medium without settling. Examples of abrasives include silica-based abrasives such as precipitated silica, silica gel, aluminosilicate, and zirconosilicate, dicalcium phosphate dihydrate and anhydride, calcium pyrophosphate, calcium carbonate, aluminum hydroxide, alumina, and carbonate. Examples include magnesium, tribasic magnesium phosphate, insoluble sodium metaphosphate, insoluble potassium metaphosphate, titanium oxide, zeolite, aluminum silicate, zirconium silicate, synthetic resin abrasives, etc., and one or more of these may be used. Can be used in combination. Among these, silica-based abrasives are preferably used from the viewpoint of cleaning power and dispersion stability.

The above-mentioned polishing agent is BE based on nitrogen adsorption.
The specific surface area measured by the T method is 100 m2/g or less, especially 5
It is preferable to use one with a density of ~30 m2/g. By using an abrasive having a specific surface area of 100 m2/g or less, changes in fluidity over time can be more effectively prevented and stable fluidity can be provided for a long time. The particle diameter of the abrasive may be the same as that of abrasives used in ordinary toothpaste, and those having an average particle diameter of 1 to 20 μm can be used.

[0014] As mentioned above, the blending amount of the abrasive is 5 to 40%, particularly 10 to 25% of the total composition. 5%
If the amount is less than 40%, the decontamination power will not be fully demonstrated.
If the amount is more than that, the fluidity will decrease.

[0015] The liquid dentifrice composition according to the present invention is formed by dispersing the above-mentioned abrasive, and the viscosity at 25°C is further adjusted to a range of 20 to 180 poise, more preferably 30 to 70 poise. , and the yield value at 25℃ is 1 to 60
Pascal, more preferably 5 to 50 Pascal, most preferably 5 to 20 Pascal. Viscosity is 2
If it is lower than 0 poise, it will be difficult to put it on the toothbrush, and 18
When it is higher than 0 poise, fluidity decreases. On the other hand, if the yield value is lower than 1 Pascal, it will be less easy to apply it to a toothbrush, and 60
If it is higher than Pascal, the fluidity will decrease. Note that the viscosity and yield value are values measured by the methods described below.

[0016] Tables 1 to 3 show the ranges of the viscosity and yield value, ease of placing on a toothbrush, fluidity in a container, and the results of a comprehensive evaluation of these.

[0017]

[Table 1]

[0018]

[Table 2]

[0019]

[Table 3] ◎: Very good, ○: Good, △: Slightly bad, ×: Bad Here, liquid toothpaste compositions with such a viscosity range and yield value range are determined by the types and amounts of the ingredients in the composition, In particular, this can be achieved by appropriately selecting the type and amount of the binder or thickening agent.

In this case, the binder includes alkali metal salts of carboxymethylcellulose, cellulose derivatives such as methylcellulose, hydroxyethylcellulose, sodium carboxymethylhydroxyethylcellulose, alkali metal alginates such as sodium alginate, propylene glycol alginate, carrageenan, xanthan gum, Gums such as gum tragacanth, gum karaya, gum arabic, polyvinyl alcohol,
Any binder used in the manufacture of toothpaste can be used, such as synthetic binders such as sodium polyacrylate and polyvinylpyrrolidone, and inorganic binders such as aluminum silica gel and laponite. These binders may be used alone or in combination of two or more.

[0021] The amount of the binder blended is the amount necessary to achieve the above viscosity and yield value, and is usually 0.0 of the total composition.
5-2%, especially 0.1-2%.

In this case, it is preferable to use a combination of xanthan gum and polyacrylate as the binder. By using this mixed binder of xanthan gum and polyacrylate, it is possible to effectively prevent changes in the liquid dentifrice composition over time, especially changes in yield value over time,
In particular, by using this mixed binder together with a silica-based abrasive, it is possible to significantly improve stability over time, and it also provides superior dispersion stability and superior cleaning compared to when other abrasives are used. Empower. Furthermore, it has been found that stringiness can be improved by using xanthan gum and polyacrylate in combination.

[0023] The mixing ratio of xanthan gum and polyacrylate is preferably 3:1 to 1:5 in terms of weight ratio, more preferably 3:2 to 1 in order to effectively exhibit the above effects. :2. In addition, the total blending amount is the above-mentioned binder blending amount, but more preferably 0.
1-1%, most preferably 0.1-0.5%, e.g. 0
．． It is in the range of 3 to 0.5%.

On the other hand, as thickening agents, glycerin, sorbitol, propylene glycol, ethylene glycol,
One or more known thickening agents such as 1,3-butylene glycol, polyethylene glycol, polypropylene glycol, xylit, maltit, and lactit are used. Its amount is usually 10-80% of the total composition.
, especially from 20 to 60%.

[0025] In the present invention, polyoxyethylene alkyl ether is blended in addition to the above-mentioned components, thereby making it possible to prevent changes in fluidity over time. In this case, as the polyoxyethylene alkyl ether, one having an added mole number of ethylene oxide of 2 to 15 is preferably used. If the number of added moles is more than 15, the dispersion stability of the abrasive may be lowered. Further, the alkyl group preferably has 8 to 18 carbon atoms, particularly preferably 10 to 16 carbon atoms. The blending amount is preferably 0.1 to 5% of the entire composition; if it is less than 0.1%, the fluidity improving effect may not be sufficiently exhibited, and if it is more than 5%, the dispersion stability of the abrasive may be affected. may reduce the

In addition to the above ingredients, the composition of the present invention may contain appropriate amounts of other anionic, nonionic, amphoteric surfactants, sweeteners, fragrances, pigments, preservatives, and various active ingredients. , can be prepared by mixing and dispersing in water.

Examples of anionic surfactants include sodium alkyl sulfates such as sodium lauryl sulfate and sodium myristyl sulfate, sodium N-acyl sarcosinates such as sodium N-lauroyl sarcosinate and sodium N-myristoyl sarcosinate, and dodecylbenzenesulfonic acid. Sodium, hydrogenated coconut fatty acid monoglyceride sodium monosulfate, sodium lauryl sulfoacetate, N-acylglutamate such as sodium N-palmitoylglutamate, sodium N-methyl-N-acyl taurate, sodium N-methyl-N-acylalanine, α - sodium olefin sulfonate,
Sodium dioctyl sulfosuccinate and the like are used.

Examples of nonionic surfactants include sugar fatty acid esters such as sucrose fatty acid ester, maltol fatty acid ester, and lactose fatty acid ester; sugar alcohol fatty acid esters such as maltitol fatty acid ester and lactitol fatty acid ester; decaglyceryl monolaurate; Fatty acid polyglycerin esters such as diglyceryl monostearate, polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monostearate, polyoxyethylene fatty acid esters such as polyoxyethylene hydrogenated castor oil, Fatty acid diethanolamides such as lauric acid mono- or diethanolamide, myristic acid mono- or diethanolamide, sorbitan fatty acid esters, fatty acid monoglycerides, polyoxyethylene polyoxypropylene copolymers, polyoxyethylene polyoxypropylene fatty acid esters, etc. are used.

Examples of the zwitterionic surfactant include N-alkylaminoethylglycine such as N-lauryldiaminoethylglycine and N-myristyldiaminoethylglycine, N-alkyl-N-carboxymethylammonium betaine, and 2-alkyl-1- Hydroxyethylimidazoline betaine sodium and the like are used.

[0030] These surfactants may be used alone or in combination of two or more. In addition, the amount of the surfactant added is usually 0.01% of the total composition.
-5%, more preferably 0.05-3%.

[0031] As fragrances, menthol, anethole,
Carvone, eugenol, limonene, ocimene, n-decyl alcohol, citronellol, α-terpineol, methyl salicylate, methyl acetate, citronellyl acetate, cineole, linalool, ethyl linalool, vanillin, thymol, spearmint oil, peppermint oil, lemon oil, orange A fragrance such as oil, sage oil, rosemary oil, cinnamon oil, pimento oil, cinnamon leaf oil, perilla oil, wintergreen oil, clove oil, eucalyptus oil, etc. alone or in combination may be used in an amount of 0 to 10% of the total, preferably 0. It can be blended in an amount of about 5 to 5%.

[0032] As sweeteners, saccharin sodium,
Stevioside, neohesperidyl dihydrochalcone,
Sweeteners such as glycyrrhizin, perillartin, thaumatin, asparatylphenylalanine methyl ester, and p-methoxycinnamic aldehyde (in the amount usually 0 to 1
%, preferably 0.01 to 0.5%).

Active ingredients include cationic disinfectants such as chlorhexidine, benzethonium chloride, benzalkonium chloride, cetylpyridinium chloride, dequalinium chloride, dextranase, mutanase, lysozyme, amylase, protease, lytic enzyme, super enzymes such as oxide dismutase,
Alkali metal monofluorophosphates such as sodium monofluorophosphate and potassium monofluorophosphate, fluorides such as sodium fluoride and stannous fluoride, tranexamic acid, epsilon aminocaproic acid, aluminum chlorohydroxylalantoin, dihydrocholestanol, glycyrrhizin One or more active ingredients such as acids, glycyrrhetinic acid, bisabolol, glycerophosphate, chlorophyll, sodium chloride, water-soluble inorganic phosphoric acid compounds, aluminum lactate, zinc chloride, and strontium chloride may be blended.

[0034] As preservatives, sodium benzoate, methyl paraoxybenzoate, ethyl paraoxybenzoate,
Examples include propyl paraoxybenzoate and butyl paraoxybenzoate.

The liquid dentifrice composition of the present invention can be made transparent by using a silica-based abrasive and making the refractive index of the aqueous medium the same as that of the silica-based abrasive.

[0036] Although there are no particular restrictions on the container containing the liquid dentifrice composition of the present invention, plastic bottles such as squeeze type and pump dispenser types are preferably used.
Aerosol containers can also be used. In particular, the container for accommodating the liquid dentifrice composition of the present invention includes a filling portion or a container body into which the contents are filled, and a mouth portion having a narrow channel through which the contents flow out. The flow path is 1 of the spatial cross-sectional area of the filling part or the container body.
/30 or less, and has a diameter of 0.2 to 8
Squeeze bottles, pump dispenser bottles, aerosol containers, etc. formed with mm-sized pores, slits, or nozzles are preferably used, and when such types of containers are used, there are problems such as the composition flowing out too much or not flowing out. You can easily take out the required amount.

[0037]

Effects of the Invention In the liquid dentifrice composition of the present invention, the abrasive is stably dispersed in the aqueous medium over time, and changes in fluidity over time are prevented as much as possible, and the composition maintains good fluidity even after long-term storage. and can be easily removed from the container.

[0038]

[Examples] Hereinafter, examples and comparative examples will be shown to specifically illustrate the present invention, but the present invention is not limited to the following examples. [021] In the following examples, viscosity, yield value, fluidity, and dispersion stability were evaluated by the following methods. (1) Viscosity Viscometer: BH type viscometer (manufactured by Tokyo Keiki Seisakusho) Rotor: No. 4 Rotation speed: 20 rpm Measurement temperature: 25℃ (2) Yield value measuring device: HAAKE viscometer control unit RV12 Sensor system MV1 Temperature 25℃ Rotation speed 0 to 128/min Straight line drawn from the origin of the shear rate/shear stress curve We measured the shear stress at the point where the (3) Fill the fluidity sample into a plastic bottle (80ml),
After storing at 50°C for 3 months, it was left at room temperature for 1 day. Thereafter, the container was tilted and the fluidity of the sample was evaluated according to the following criteria. Evaluation criteria: 5 points: Flows quickly 4: Flows 3: Flows somewhat slowly 2: Flows slowly 1: Does not flow even when tilted (4) Dispersion stability A plastic bottle (80 ml) is filled with the sample,
It was stored in a constant temperature bath at 40° C. for one month, and phase separation was visually judged according to the following criteria. ○: No change in appearance, good ×: Sedimentation of abrasive or syneresis phenomenon observed (5) Overall evaluation Viscosity: 20-180 poise/25°C Yield value: 1-60 Pascal/25°C Fluidity: 4 points or more Dispersibility: ○ The case where the above conditions were met was judged as good (◯), and the case where even one item was not satisfied was judged as poor (x).

[Example 1] Zirconosilicate
15% Butyl paraoxybenzoate
0.01 xanthan gum

0.2 Sodium polyacrylate
0.2 Propylene glycol
2 Sorvit

35 Glycerin

8.5 Saccharin Sodium
0.1
fragrance
1 Pigment (Brilliant Blue)
0.001 Sodium lauryl sulfate
1 Sodium fluoride
0.2
polyoxyethylene lauryl ether
1 (Number of moles added: 12) Pure water
Residue


100.0% Viscosity (Poise): 50 Yield value (Pascal): 8 Fluidity: 5 Dispersion stability: ○ Overall evaluation: ○

[Example 2] Precipitated silica
20% carboxymethylcellulose sodium
0.15 carrageenan

0.2 Propylene glycol
2 Sorvit
35 Glycerin

8.5 Saccharin Sodium

0.1 Fragrance

1 Pigment (Brilliant Blue)
0.001 Sodium lauryl sulfate
0.5 Polyoxyethylene cetyl ether 2
(Number of moles added: 5) Pure water
Residue


100.0% Viscosity (Poise): 60 Yield value (Pascal): 10 Fluidity: 4 Dispersion stability: ○ Overall evaluation: ○

[Example 3] Aluminosilicate
15% xanthan gum
0.1 carrageenan

0.2 Propylene glycol

2 Sorvit
20 Glycerin
20 Saccharin sodium
0.1 Fragrance

1 Pigment (Brilliant Blue)
0.001
sodium lauryl sulfate
1.5 Polyoxyethylene stearyl ether 0
．． 5 (Number of moles added: 11) Pure water
Residue


100.0% Viscosity (Poise): 35 Yield value (Pascal): 5 Fluidity: 5 Dispersion stability: ○ Overall evaluation: ○

[Example 4] Dibasic calcium phosphate
30% carboxymethylcellulose sodium 0.
15 Carrageenan
0.15
Propylene glycol
2 Sorvit

20 Glycerin

15 Saccharin sodium
0.1
fragrance
1
sodium lauryl sulfate
1 Polyoxyethylene stearyl ether 1.5
(Number of moles added: 2) Pure water
Residue

1
00.0% Viscosity (Poise): 53 Yield value (Pascal): 6 Fluidity: 5 Dispersion stability: ○ Overall evaluation: ○

[Example 5] Precipitated silica
10 Xanthan gum
0.2 carrageenan

0.25 Propylene glycol
2 Sorvit
15
glycerin
30 Saccharin sodium
0.1 Fragrance

1 Pigment (Brilliant Blue) 0.
001 Sodium lauryl sulfate
0.5 Polyoxyethylene lauryl ether
3 (Number of moles added: 12) Pure water
Residue


100.0% Viscosity (Poise): 40 Yield value (Pascal): 5 Fluidity: 5 Dispersion stability: ○ Overall evaluation: ○

[Comparative Example 1] Aluminosilicate
30% xanthan gum
0.2 Sodium polyacrylate
0.2 Propylene glycol
2 Sorvit
30 Glycerin

15 Saccharin sodium

0.1 Fragrance

1 Pigment (Brilliant Blue)
0.001 Sodium lauryl sulfate
1.5 Pure water

Residue

100.0% Viscosity (Poise): 85 Yield value (Pascal): 18 Fluidity: 1 Dispersion stability: ○ Overall evaluation: ×

Claims (1)

[Claims] Claim 1: 5 to 40% by weight of abrasive in an aqueous medium.
It is characterized by blending polyoxyethylene alkyl ether into a liquid toothpaste composition which contains polyoxyethylene alkyl ether and has a viscosity at 25°C in the range of 20 to 180 poise and a yield value at 25°C in the range from 1 to 60 Pascal. A liquid dentifrice composition.