JPH0411524B2 - - Google Patents

Description

[Detailed description of the invention]

The present invention relates to a toothpaste container. More particularly, the present invention relates to toothpaste tubes containing separated reactive components that interact and foam when brought into contact during a dentifrice operation. Sodium bicarbonate, also known as calcined soda, is used for a variety of purposes and is a common household product. Recommended for use in toothpastes such as toothpaste and toothpaste. The commercialization of a practical and effective "calcined soda toothpaste" that is acceptable to consumers presents many special problems to inventors and manufacturers. Factors to consider include its unique properties (chemical,
physical and cosmetic properties). For example, they are relatively water soluble, have low stability, and tend to release _CO2 in aqueous systems. Although it tastes salty, flavor is one of the more important aspects in the purchase and use of oral products and toothpastes. Other factors that should be considered in the formulation and manufacture of a suitable product include product cleanliness, abrasiveness, stability in the container, appearance during dispensing, and special manufacturing considerations. The present invention now allows for the production and dispensing of a novel calcined soda toothpaste that is believed to be effective in promoting dental and oral hygiene and acceptable to consumers.
Such products have useful cleaning, abrasive, and other desirable properties and are beneficial to various parts of the human tooth (including the tooth and its surrounding or adjacent elements; e.g., plaque, tartar, gingiva, mucous membranes, saliva, etc.). have an effect. In particular, genuine toothpaste leaves the user with clean breath. By employing a two to multi-compartment dispensing container, the product can be formulated to be stable over time or storage without significant early release of _CO2 , undesirable segregation or reactions. U.S. patents whose inventors are both Delaney et al.
Nos. 3937804, 3943240, and 4160022 invention publications state that the abrasive is sodium bicarbonate, non-reactive calcium carbonate (chalk), silica, alumina, zirconium silicate, sodium aluminosilicate, and other compatible salts of silicic acid or carbonate. A calcined soda toothpaste comprising one or more of the following is described. “Other” abrasives are
Ca carbonate is preferred as it helps to protect and stabilize the calcined soda toothpaste (the calcined soda is present in the aqueous vehicle) from substantial formation of CO ₂ during storage. However, this stabilizing effect may result in an undesirable reduction in foaming due to inhibition of CO ₂ formation during toothpaste use. It is an advantage of the present invention to provide a storage stable effervescent soda toothpaste. A second advantage is that the acidic agent reactive with the calcined soda is provided in a compartment separate from the calcined soda-containing compartment in the container (dispensing vessel or tube). The container is constructed such that during toothpaste extrusion, the acid agent-containing portion and the calcined soda-containing portion are dispensed together and foam during the tooth brushing operation. Another advantage is that the foaming is greater than that obtained in the absence of the acidic agent, and the results are about the same when the stabilizing abrasive is removed (when a non-stabilizing agent is substituted). Other advantages of the invention will be apparent from the description herein. In certain embodiments, the present invention relates to containers. A container for dispensing ingredients of a toothpaste that foams in the human mouth during a tooth brushing operation, consisting of two separate toothpaste parts; both parts contact each other separately in separate parts of the toothpaste container before extrusion. the first portion contains approximately 5-35% water by weight of the first portion; a vehicle comprising a viscous, water-miscible polyol humectant and a gelling or thickening agent sufficient to provide viscosity; at least about 15% by weight Na bicarbonate; and bicarbonate.
The second part consists of about 1-30 W% of a water-insoluble tooth polishing agent that is non-reactive with Na; the second part consists of water, a viscous, water-miscible polyol humectant, and a mixture of water and such humectant. a vehicle comprising a liquid selected from;
PH approximately 1.5-5.5 in water at concentrations within the range of 0.5-10%
When it comes into contact with the sodium bicarbonate, it can react with it and foam with the formation of CO ₂ . and about 1 to 20 W% acidifying content of the second portion. Traditionally, those skilled in the art have been concerned with separating reactive components in toothpaste during storage. This is Rhein's US Patent No. 1297494 (Reissue No. 14961);
Fleischman, US Pat. No. 2,035,267; Davis et al., US Pat. No. 3,087,857; Scheller et al., US Pat. U.S. Pat. No. 1,297,494 describes an anhydrous toothpaste in which the reaction between acidic salts and sodium bicarbonate is combined with saliva due to the presence of natural anhydrous agents such as glycerin and thick gums (e.g. gum arabic). It is stopped before contact. US Pat. No. 2,035,267 discloses that perborate and sodium bicarbonate in the presence of a relaxing acid such as agaric acid in anhydrous toothpaste.
It is stated that the initial reaction with perborate and bicarbonate can be avoided by coating the perborate and bicarbonate with stearate and the acid with cloid clay. US Pat. No. 3,087,857 states that potassium bicarbonate is present in a non-aqueous veterinary oral spray containing sodium bicarbonate, which foams upon contact with animal saliva. US Pat. No. 3,577,521 states that acidic salts are present in low water content toothpastes containing percompounds to induce foaming. British Patent No. 1565672 discloses a toothpaste in two separate packages, one containing a water-insoluble peroxide or peroxy salt and the other containing an organic acid or acid salt. The contents of each package are maintained separately until the time of use. Other related documents are US patents 1535529; 3966863; 3980767; 4066745;
No. 4328205; French patent No. 2327762. The present invention has successfully stabilized the sodium bicarbonate in one part by the presence of a suitable water-insoluble tooth polishing agent, and in the second part induces a reaction with this stabilized bicarbonate. The present invention is distinguishable from the prior art as it relates to a toothpaste container which provides the user with a foaming sensation and the desired cleaning effect of the CO ₂ gas generated in situ. It is noteworthy that unlike the invention of British Patent No. 1565672, it is not necessary to completely avoid contact between the two parts until use. Furthermore, a toothpaste compartment container is used which allows constant interfacial contact between both parts from the time of discharge from the container. Each part of the toothpaste of the present invention is packaged in a separate part of the container and simultaneously extruded, applied to a toothbrush, and used in a tooth brushing operation. During dispensing, no or only slight foaming occurs, but as the contact between the sodium bicarbonate and the acidic compound increases during the tooth brushing process, the foaming increases dramatically. The invention can be easily understood with reference to the accompanying drawings. In FIG. 1, the dispensing tube 11 is provided with a cap 13 for closing it during storage and when not in use, and includes a body 15 and two inner envelope bodies 17, 19 (considered in mutual contact along surface 21). ). As illustrated, the envelopes 17, 19 form compartments containing the first and second portions 23, 25 of the foam toothpaste of the present invention. A threaded collar 27 on the neck of the tube 11 serves to make such a neck rigid, and is not necessary; means (not shown) for making the envelope body 17, 19 rigid near the neck if desired. It can also be equipped. As illustrated, the toothpaste is dispensed simultaneously as two ribbons or stripes. If a multi-stripe effect is desired, suitable means can be inserted into the neck of the tube to achieve such an effect. Some such measures include second and third
Although shown in the figures, they can be modified as desired and to suit specific tube designs. FIG. 2 illustrates an alternative tube for making a striped foam toothpaste. tube 3
1 is an improved version of the one shown in US Pat. No. 4,211,341, in which an adapter ring 33 is placed within the neck 35 to create a striped effect. The tube 31 has a wall 37, a neck 35, and a threaded collar 39. First part of tooth brushing 43
It includes an internal separation vessel 41 filled with. A second portion 45 of the toothpaste is shown between the container 41 and the wall 37.
The proportion of both parts can be controlled by varying the depth of the inner container 41, leaving a larger or smaller volume near the collapsed bottom 47 of the collapsible tube. When the adapter 33 is in place within the neck of the tube, the first portion of the dentifrice is completely surrounded by its second portion during normal dispensing. However, as shown in the example, the ring 33
(which has holes, as illustrated, for example, at 49) block the flow of portions of the second portion and expose the first portion at regular intervals around the extruded ribbon to create a striping effect. As illustrated, toothpaste ribbon 51 exhibits such striping due to the use of a colorant in one toothpaste portion. As also shown, the dispensed toothpaste does not expand excessively and retains its normal shape when applied onto the bristles 53 of the toothbrush 55. The toothpaste container of FIG. 3 is similar to that shown in U.S. Pat. No. 4,098,435, but shows an alternative mechanism for making striped foam toothpaste in accordance with the present invention. The container 61 has a first tooth brushing section 63 and a second tooth brushing section 65 separated by a separating means 67. It can be seen that the holes 69, 71 in the fitting 73 allow the second dentifrice portion to be deposited in a stripe onto the first portion as it is forced out of the collapsible tube. The separation device 67 can be made of any suitable material and can be positively coupled to a fitting 73, envelope means (not shown), for retaining the dentifrice portion 63 within the tube 61. Additionally, the neck 75 of the tube 61 and the threaded collar 77 are used to prevent undesirable reactions within the tube after the toothpaste parts come into contact with each other.
can be shortened and/or holes 69, 71 can be extended "downstream" in communication with the tube so that contact between different parts of the toothpaste only occurs very close to the tube exit. Instead of dispensing the two dentifrice parts together, the larger one may be included in a single tube or other suitable multi-compartment dispenser. For example, several colors and stripes can be used if desired. In addition to the illustrated dispensing containers, other devices known in the art, such as U.S. Pat. No. 2,789,731,
You can also use the one from No. 3881529 instead. Other types of dispensers can also be used, such as "aerosol" or pressurized gas operated cans. The inner surface of the tube is made of lined or unlined Al, lined lead or plastic and is easily collapsible;
The toothpaste part can be easily pushed out using manual pressure. Preferably, in the extrusion one part appears as a stripe on the other or as a core partially (or completely) wrapped by a region, and various other relationships are possible for the two extruded parts. The toothpaste portion present in the dispensing container has a first portion to second portion weight ratio of about 0.5:1 to 40:1, preferably about 0.7:1 to 20:1, more preferably about
0.8:1 to 5:1, most preferably (usually)
The ratio is approximately 1:1. The first part of the toothpaste, the part containing sodium bicarbonate, is stable and non-foaming. Although sodium carbonate particles are relatively soft compared to most conventional abrasive particles used in toothpastes, they exert a physical cleaning effect on teeth.
For example, in a radioactive tooth abrasiveness (RDA) test, a toothpaste containing about 50% Na bicarbonate as the only abrasive has an RDA value of about 100, whereas the toothpaste vehicle tested (without including the bicarbonate) the RDA value was only about 50. The first part of the toothpaste usually contains at least about 15%, preferably about 15-50% Na bicarbonate. More preferably it is about 20-40%, for example 30%. The sizes of these Na bicarbonate particles are coarse and fine. The diameter is
Much smaller than 0.4mm, most of the weight is the diameter
Na bicarbonate, preferably larger than 0.01 mm
Although the vehicle in which the particles are dispersed is aqueous, it is preferably in an amount and nature such that the majority or substantially all of the sodium bicarbonate is insoluble in the toothpaste.
However, it should be understood that when brushing your teeth with this toothpaste, the sodium bicarbonate particles tend to dissolve in your saliva.
Such dissolution is facilitated by the presence of water in the toothpaste, accelerating foaming and improving the flavor and other properties of the toothpaste compared to toothpastes containing only non-aqueous vehicles. The auxiliary abrasive is preferably Ca carbonate (chalk). The presence of chalk or other suitable stabilizing abrasives improves the stability of the bicarbonate portion of the toothpaste over time at elevated temperatures. Chalk, silica (sodium aluminosilicate)
and/or bonded alumina-containing silica),
The addition of compatible water-insoluble abrasives such as alumina, zirconium silicate, etc. or suitable mixtures thereof provides stable Na bicarbonate compositions that provide improved cleaning power with resistance to flavor separation. have,
Also, there is no tendency to form gases during storage. In contrast, when common tooth abrasives such as dicalcium phosphate and insoluble sodium metaphosphate are added to the same sodium bicarbonate composition, even short-term (e.g., 1 day) storage at elevated temperatures results in excessive amounts of tooth abrasives. Gas is formed. The resistance to separation of the flavoring agents in this product is demonstrated by the reduced tendency of the essential oils used as flavorants to separate from the toothpaste over time at 43-49°C. This separation is bicarbonate
It occurs most violently when the Na particles are relatively large in size, e.g., 150 microns or more in diameter. The average particle size of the chalk is preferably less than 20 microns;
10-1 micron is most preferred. Silica may be crystalline or amorphous. In all cases the particle size is preferably less than 20 microns, for example from 2 to 10 microns.
Micronized crystalline silica or silica gel, such as silica gel sold under the trade names Syloid 63 and Syloid 74, are examples of useful silica. Alumina may be of hydrated or non-hydrated type. For hydrated alumina, the average particle size is preferably less than 20 microns, most preferably less than 10 microns, and most preferably greater than 1 to 2 microns. When using zircon silicate, its average particle size is less than 5 microns, such as less than 3 microns and 0.3
Larger than microns is preferred. Particularly suitable alumina is α-
It is in the form of alumina crystals. The flake is (weight)
The average particle diameter is less than about 7 microns, such as about 2 to 7
It is micron. This flat α-alumina crystal and its manufacturing method are described in US Pat. No. 3,121,623. Preferably, the toothpaste is substantially free of anhydrous alumina particles about 15 microns in diameter and about 2 microns thick. The use of alumina flakes whose average particle size is less than 5 microns, e.g. 3-4 microns, is most preferred, although alumina flakes of larger diameter and similar thickness, such as those described in the aforementioned U.S. Pat. 9, 12 or 15 microns or more in diameter, with no particles greater than 40 microns in diameter (preferably no particles greater than about 20 microns in diameter), and with a thickness greater than about 3 microns. Virtually free alumina flakes,
Also within the scope of this invention is the use of In a preferred form of the invention, the α-alumina flakes are uncoated and non-adhesive to particles of other materials. It is within the scope of this invention to use α-alumina or other abrasives of moderate hardness (sometimes about 6 on the Moh scale) mixed with α-alumina flakes. For example, about 1/2 of the alumina flakes can be made of micronized alpha-alumina that is irregularly shaped and has an average particle size of about 3 to 4 microns (all of the irregular particles' longest dimension being less than about 7 microns). Can be substituted. Thus, the toothpaste may contain, for example, 3% of said flakes and 2% of said irregular particles. A typical alkali or alkaline metal aluminosilicate has a refractive index of about 1.45 and a water content of about 5 to 20.
%, e.g. 10%, alumina content up to about 10%, e.g. 8%, silica content at least about 70%, Na oxide
(or other alkali metal or alkali ± metal oxides, e.g. Ca oxide) content up to about 10%, e.g. 7%, particle size less than 40 microns, preferably about 1
~20 microns, is a complex. Examples of abrasive mixtures are equal or about 25/75 or 75/
It is a blend of 25 parts chalk and hydrated alumina. The composition may also include a small amount of titanium dioxide powder, which has been found to have a significant abrasive effect on teeth when used in a sodium bicarbonate composition. _TiO2
Preferably, the particle size is about 0.1 to 1 micron. The amount of titanium dioxide particles in the composition is low;
About 0.1~10W% of Na bicarbonate, preferably about 0.1~
5W%, more preferably about 0.5-1 to 2W%. The above percentage of TiO ₂ (and other components) is based on the percentage and ratio of other components in the product, the amount of water present (5 to 35%),
Water:glycerin ratio (3:1 to 6:1), bicarbonate
Na content (25-60%), amount of different abrasives (1-30%)
It can be easily calculated from etc. For example, the amount of _TiO2 present is up to about 5-6% of the toothpaste, preferably about 0.2-6%.
It is 0.6W%. The total amount of abrasive (excluding _TiO2 ) in the first portion is about 1-30%, preferably 3-25%, more preferably 5-20%. The vehicle in the first part of the toothpaste is a suitable liquid (preferably containing a thickening agent, such as a gelling agent). Preferably, the vehicle is aqueous, although the use of non-aqueous vehicles is within the scope of this invention. This liquid typically contains humectants and other viscous water-miscible substances.
Examples include glycerin, sorbitol, polyethylene glycol, maltitol, mannitol or suitable mixtures thereof. Water accounts for about 5-35%, such as about 10-30%, of the total vehicle in the first portion. Good results (eg flavor) are obtained when the proportion of water is about 10-20% of the total toothpaste. Normally, the ratio of sodium bicarbonate:water is about 0.3:1 in real toothpaste at the time of dispensing.
~8:1, for example 0.5:1 to 3:1, and in the first tooth brushing part 0.6:1 to 10:1, in many cases
0.8:1 to 6:1, for example 3:1 to 6:1. The presence of such a large proportion of water causes the toothpaste to foam rapidly in the mouth. Gelling agents for toothpaste vehicles are well known in the art. These are often higher grade polymers, such as gums or other thickening agents, which are soluble or swellable in water or other aqueous media. Carboxymethyl cellulose Na shows excellent results. Other useful materials are gum tragacanth, gum acacia, gum karaya, sodium alginate, hydroxyethylcellulose, methylcellulose, ethylcellulose,
Thickening agents such as carrageenan and other polysaccharides, xanthan, polyvinylpyrrolidone, "Vegum" (composite magnesium aluminum silicate), and silica aerogel, etc. Preferably, the amount of thickening agent used in the practice of this invention is sufficient to impart pasty consistency, texture, and non-viscosity (characteristics of conventional toothpastes) to the mixture. As is well known, such toothpastes can be extruded from ordinary collapsible toothpaste tubes to form ribbons of considerable thickness (e.g., about 0.5 to 1 cm), which when left in place will reduce the original thickness by 1 cm.
It holds substantially for more than a minute, and even when placed on the upper end of toothbrush bristles for a similar period, it does not substantially get into the bristles. Such toothpaste ribbons can be used for tooth brushing operations,
For example, it is preferable that the material exhibits considerable resistance to deformation when touched lightly with a finger. Also, such ribbons have little tackiness and therefore do not tend to form strings when the finger is removed from the ribbon. These properties serve to prevent undesirable premature reactions of the extruded toothpaste parts with each other before tooth brushing begins. The proportion of thickening agent in the first part of the toothpaste of the present invention is about 0.5-2%,
For example, it is preferably about 0.8 to 1.5%. It is highly preferred to use organic surfactants in the composition to aid in its prophylactic action, complete dispersion in the oral cavity, and to improve cosmetic value, cleaning, and foaming properties. Its surface activity helps promote the reaction between the bicarbonate and acidic substances, thus helping to increase the degree of foaming. Organic surfactants include water-soluble salts of higher alkyl sulfates, such as sodium lauryl sulfate,
Suitable alkyl sulfate salts _whose alkyl group is _C8-18 ; water _- soluble salts of sulfonated monoglycerides of higher fatty acids, such as coconut monoglyceride sodium sulfonate and other suitable sulfonated monoglycerides of _C10-18 fatty acids; higher fatty acids (e.g.
salts of amides _{of C12-16} acids) with lower aliphatic amino acids, such as taurine, sarcosine and other _C2-6 amino acids, such as Na-N _- methyl-N-palmitoyltauride; sodium N-lauroyl;
N-myristoyl- or N-palmitoyl sarcosinates; water-soluble salts of esters of such fatty acids with isethionic acid or glycerol monosulfate, e.g. Na salts of monosulfated monoglycerides of hydrogenated coconut oil fatty acids; olefin sulfonates, e.g. Water _- soluble salts of alkenesulfonates, hydroxyalkenesulfonates, and mixtures thereof whose C chain is _C12-16 ; water _- soluble soaps of higher fatty acids, such as _C12-18 fatty acids such as coconut fatty acids; The cation of the salt is Na (preferred), K or mono, cy or trietahalamine. Mixtures of surfactants can also be used. A suitable mixture to provide a highly foaming powder with little or no irritating effect is about 1:2 to 2:
The composition is composed of a higher alkyl sulfate and a higher fatty acid sarcosinate in a ratio of 1:1, for example, and a higher fatty acid monoglyceride sulfonate or other surfactant may be present in place of all or part of the sarcosinate. Other such surfactant mixtures can also be used. Other suitable surface-active substances are nonionic agents, such as condensates of sorbitan monostearate and about 20 times the molar amount of ethylene oxide;
Condensates with propylene oxide-propylene glycol condensates (available under the trademark "Pluronics"); amphoteric agents such as quaternized imidazole derivatives available under the trademark "Miranol" such as Miranol C ₂ M; Cationic surfactant disinfectants, antibacterial compounds can also be used. Such compounds are diisobutylphenoxyethquinethyldimethylbenzylammonium _chloride , benzyldimethylstearylammonium chloride, one N-bonded fatty alkyl group ( _C12-18 ) and two (poly)
tertiary amines having oxyethylene groups (typically having about 2 to 50 ethenoxy groups/molecule);
These include salts of these with acids, compounds of the following formula, and salts of these with mineral acids and organic acids. (R is _{a C12-18} fatty alkyl group; x and y are 3 or more in total) In the present dentifrice, it is preferable to use one or more of the above-mentioned surfactants in an amount of about 0.05 to 5% of the total amount. The proportion of surfactant in the first toothpaste part is usually about 0.05-5%,
Preferably it is about 1-3%, for example about 1 1/2-2%. The second portion may also contain a similar percentage of surfactant, but is often not used. According to certain embodiments of the invention, cationic antimicrobial agents can be included in the compositions of the invention. Such agents include ^N1- (4chlorobenzyl) ^-N5- (2.4-dichlorobenzyl)biguanide; P-chlorophenylbiguanide; 4-chlorobendihydrylbiguanide; 4-chlorobendihydrylguanylurea; N-3- lauroxypropyl- ^N5 -P-chlorobenzyl biguanide; 1-(lauryldimethylammonium)-8-P
-chlorobenzylmethylammonium) octane dichloride; 5,6-dichloro-2-guanidinobenzimidazole; ^N1 -P-chlorophenyl- ^N5 -lauryl biguanide; 5-amino-1,3-bis(2-ethylhexyl)-methyl Hexahydropyrimidine cetylpyridinium chloride; and non-toxic acid addition salts thereof, especially fluoride and dihydrodiene fluoride. 1,6-
Di-(P-chlorophenyl-biguanidihexane)
is particularly preferred. These agents are about 0.01~
Can be used in an amount of 5W%. Of course, when the first part contains anionic surfactants or other anionic agents that may react with the antimicrobial agent, the cationic agent is best included in the second part, which does not contain such reactive components. Any suitable flavoring or sweetening agent may be used in the flavor formulation of the compositions of the present invention. Examples of suitable flavoring ingredients are flavored oils such as spearmint, peppermint, wintergreen, satsafras, clove, sage, eucalyptus, marjoram, cinnamon, lemon,
orange oil and methyl salicylate. Suitable sweetening agents are lactose, maltose, sorbitate, sodium cyclamate, perillartine, saccharin, ammoniated glycyrrhizin (eg as its monoammonium salt). Suitably, the total amount of flavoring agents and sweetening agents accounts for about 0.01 to 5% or more of the composition. Preferably, the amount of flavored oil is 0.5
%, for example 0.7-2% or 0.8-1.2%, sweeteners 0.1-4 or 0.1-0.5% (the latter in the case of artificial sweeteners such as saccharin). The first portion may also include a fluoride-containing anti-caries agent. There are many water-soluble inorganic salts that are suitable sources of F ions. They are Na, K, ammonium,
L; is an amine fluoride. Monofluorophosphates are also useful, Na ₄ P ₃ O ₉ F, K ₄ P ₃ O ₉ F,
(NH ₄ ) ₄ P ₃ O ₉ F, Na ₃ KP ₃ O ₉ F,
(NH ₄ ) ₃ NaP ₃ O ₉ F, Li ₄ P ₃ O ₉ F. Fluorosilicate (Na ₂ SiF ₆ ), Fluorozirconate (Na ₂ ZrF ₆ ), Fluorostannate (KSnF ₃ ), Fluoroborate (NaBF ₄ ), Fluorotitanate (NaTiF ₅ ), Fluorogermanic acid Salt (K ₂ GeF ₆ )
Complex water-soluble fluoride-containing salts such as fluoride-containing salts can also be used.
F ions can also be supplied by organic fluorides that produce F ions in water. Suitable such organic compounds are mono-, triethanolamine hydrofluoride. These are present in effective but non-toxic amounts, usually in a range to provide a water soluble F content of about 0.01-1 W% (dentifrice base).
NaF and Na monofluorophosphate are preferred compounds. Various other substances can also be incorporated into the dentifrices of the present invention.
Examples are colorants, whitening agents (some of which have already been mentioned), preservatives, silicone trichlorophyll compounds, and mixtures thereof. These adjuvants are incorporated into the present composition in amounts that do not substantially impair the desired properties thereof, and are selected and used in appropriate amounts depending on the particular type of formulation. Although it is preferred that the colorant (often only 0.0001-0.1% of the total toothpaste) be entirely in the second part to create an attractive striped toothpaste, this is not a requirement.
It may be present only within the first portion or within both portions, and different colors may be used in both portions. The second portion of the toothpaste of the present invention is maintained physically separate from the first portion prior to extrusion from the toothpaste container;
a liquid vehicle selected from the group consisting of water, at least one viscous water-miscible polyol humectant and mixtures thereof;
Approximately 1-20 W% of the second portion exhibiting a PH of 1.5-5.5 and capable of reacting with the Na bicarbonate of the first portion to foam the bicarbonate with formation of _CO2 . It consists of acidic compounds. The preferred pH range is about 1.5-3. The vehicle is water, glycerin, soybean,
Polyethylene glycol, malt, mannite, or any mixture thereof
It is most preferable to use it as a percentage. This vehicle can be formulated similarly to the vehicle for the first part to give both parts similar physical properties, which makes them physically compatible, and also allows them to be of different colors and formulated. This allows for the creation of an attractive striped appearance which is desirable when extruded together from the toothpaste container. In particular, the same amount of gelling or thickening agent as present in the first part may be present in the second part. The second part may also include other components described as being able to be included in the first part, as long as they are non-reactive with the acidic compound. Examples of water-insoluble abrasives that can be used in the second part are common toothpaste abrasives, such as insoluble sodium metaphosphate, dicalcium phosphate,
(anhydrous and/or dihydrate), Ca pyrophosphate, silica (including Na aluminosilicate, ie, silica bonded to alumina), zircon silicate, and the like. However, the condition is that it is stable and non-reactive with the acidic compound. However, in many cases such abrasive can be removed from the second portion, or its proportion is less than in the first portion. The second part of the toothpaste can be formulated as a visually clear to opaque composition with or without an abrasive. Such effects can also be obtained from the first part. The degree of foaming obtained when the acidic compound of the second part comes into contact with the sodium bicarbonate of the first part after extrusion from the toothpaste container depends on the mutual weight ratio of the first part and the second part (useful range is about 0.5; 40:1 to 50:1, preferably 0.7:1 to 20:1, more preferably 0.8:1
~5:1, e.g. 1:1) and can be adjusted by varying the relative amounts of Na bicarbonate and acidic compound present in the total toothpaste. Approximately 20-40W% bicarbonate
The ratio is about 1:1 to 10:1 when Na is present in the first part and about 4 to 10 W% of the acidic compound in the second part.
It is desirable that Acidic compounds that can be present in the second part are malic acid,
These are alginic acid, citric acid, succinic acid, lactic acid, avalanitic acid, potassium barbitrate, acidic sodium citrate, phosphoric acid, acidic phosphate, and pyrophosphate, such as sodium phosphate and di-sodium pyrophosphate. Acids are preferred, especially organic acids. The acidic compound is in the second portion of about 1 to
20W%, preferably 2-15W%, more preferably about 4-10W%. The following examples are illustrative of the invention. All proportions and amounts herein are by weight unless otherwise specified. Example 1 As illustrated in FIG. provided an unlined aluminum toothpaste tube container (similar to the aforementioned patent container) in which when the tube is squeezed, the two compositions in the two compartments are forced out of the orifice of the tube in an approximately 1:1 weight ratio. (The containers shown in Figures 2 and 3 could also be used instead.) When extruded, one part appeared as a stripe on the other, and the toothpaste was composed of two such different "stripes." To create more stripes, any of the various devices for the tube neck (internal deflectors) as illustrated in the accompanying drawings or others shown in the accompanying drawings and the above-mentioned patent documents may be used. A dispensing mechanism could also be used. A toothpaste having the following formulation of Part 1 was dispensed into the first compartment of the tube, and a composition having the formulation of Part 2 was dispensed into the second compartment. Both formulations are as follows.

[Table] When the toothpaste was extruded from the compartment toothpaste container, the two parts came into interfacial contact and part 2 appeared as a clear blue stripe on the surface of part 1. Contact between the two parts was enhanced when the toothpaste was pushed onto the toothbrush and used to brush the teeth and gums. Such contact resulted in significant foaming and effective tooth abrasion, and cleaning and abrasion upon good contact with the treated tooth area was aided by the accompanying release of _CO2 . Without Part 2, foaming was much lower, while with Part 1 alone the noticeable flavor and mouthfeel was reduced. The toothpaste of the present invention initially has a salty taste, which changes during the brushing operation (due to the foaming reaction) to a pleasant, sweeter, minty flavor. This toothpaste is sufficiently stable before the toothbrushing operation that it does not deform while it is held on the toothbrush (usually for 1 to 10 seconds before the toothbrushing operation); It is believed that it depends on the presence of applied chalk or other compatible abrasives and their effect on the bicarbonate in Part 1. The effervescence also enhances the flavor and enhances the perception of use. Examples 2 and 3 The toothpaste part 1 of Example 1 was replaced with the next part 2 in another compartment.
-2 and 2-3 in a compartmentalized aluminum tube container (a plastic tube could also be substituted) (1:1 ratio).

[Table] Parts 2-2, 2-3 when using toothpaste for brushing teeth
Significant effervescence occurs during the contact mixing of each of the parts with part 1, which aids in cleaning the teeth, promotes mixing of both parts, helps the salty taste change to a pleasant sweeter flavor, and improves the taste in the mouth. A unique flavor was created. Moreover, the toothpaste ribbon did not deform when extruded and held on a toothbrush prior to use. Examples 4-6 Compositions named toothpaste parts 1-4 (prescriptions described below) were blended into each compartment of three two-compartment toothpaste containers similar to those illustrated in the accompanying drawings, and parts 2-4, 2-5,
Equal parts of the composition designated 2-6 were filled into the other compartment of the tube. Part component part 1-4 Glycerin 33.415 Carboxymethyl cellulose Na 0.950 Silica airgel (thickening agent) (Syloid244)
0.200 Sodium benzoate 0.500 Sodium saccharin 0.200 Ca carbonate 5.000 Sodium bicarbonate 40.000 Sodium lauryl sulfate 1.500 Titanium dioxide 0.400 Flavoring agent 1.000 Deionized water Balance 100.000

[Table] When the product is pressed out of the container onto a brush and brought into good contact with the teeth and gums by brushing, significant foaming occurs in each case, accompanied by the excellent cleaning effect, pleasant flavor effect, and mouth feel mentioned above. Ta. The above embodiments are but a few of the many suitable embodiments of the invention. Naturally, other humectants (i.e. polyols), gums (i.e. thickeners), abrasives, stabilizers,
Surfactants, colorants, flavoring agents, acidic substances can be substituted for the illustrative examples, and various mixtures thereof can also be used. Furthermore, the example percentage is also ±10%, for example.
Variations of ±25% are possible and still within the scope of this invention. The proportions of each part can also be varied within the above ranges. In some cases, instead of two parts, three or more can be used, sometimes of different colors or appearances. Instead of dispensing toothpaste from a collapsible tube, a pressurized container of suitable design can be used. Although striped toothpastes with a greater number of stripes, such as those described in the Examples, are preferred, products with marbled, mottled and other mixed effects are also within the scope of the invention. An important aspect is to keep the different reactive parts of the dentifrice separate and stable until dispensing. Although various advantages of the present invention have been described above, they will be summarized below, and some desirable effects will be added. This toothpaste tube has those compartments,
It can be made by integral molding, such as by blow molding when making plastic tubes.
The tubes are sometimes made of plastic (e.g. polyethylene or polypropylene) which can retain both the alkaline and acidic portions of the toothpaste, so no special lining or coating is required and standard tube materials currently available can be used. If any of the components of any part of the toothpaste react with the tube inner wall material, such inner walls may be specially coated or lined with a material resistant to harm caused by such toothpaste parts. Within the scope of the present invention. For example, in aluminum tubes, one should be careful about the acidity of the second part of the composition of Example 1, and half of the toothpaste (second part).
When inserting a polyethylene tube suitable for holding the plastic tube into the aluminum tube and filling both parts, such filling can be done simultaneously in the aluminum tube outside the plastic tube and in the plastic tube. In such cases, the plastic tube has an internal neck designed to eject approximately equal or other desired amount of the second portion along with the first portion ejected from the aluminum tube on the outside of the plastic tube.
By varying the outlet of the tube or other dispenser, different types of stripes and other effects can be obtained, and such stripes can become sensual when acidic substances are present in the stripe section. While the toothpaste swells slightly while on the toothbrush due to contact with acidic substances and sodium bicarbonate, the stripes do not swell, which is an interesting macroscopic effect and can be of interest to the user. but,
The expansion of the first portion is not significant and does not unduly distort the toothpaste ribbon. Also, the striping material is not merely decorative, but functional, and means of effectively coloring or visually altering the toothpaste are also used according to the invention to give it another desirable effect (foaming). However, this does not require any additional changes to the structure of the dispensing container. The effect of effervescent toothpaste is to help clean the teeth and to disperse and dissolve the various ingredients in the toothpaste. In fact, this foaming also promotes the reaction between the bicarbonate and the acidic reactant by bringing them into intimate contact. It also helps to separate stabilizing agents such as chalk and other abrasives from the bicarbonate, promoting more foaming as acidic materials react with the bicarbonate. This effervescent effect on the palate and sensory organs of the mouth and tongue is highly desirable. Acidic substances and CO ₂ bubbles become one,
Alternatively, flavorants in toothpastes may also be used to produce different flavor effects that change during the tooth brushing operation. That is, the flavor is initially somewhat acidic but also salty, due to the acidic substances and the dissolution of the Na bicarbonate. However, as the tooth brushing process continues, the pH becomes neutral or slightly alkaline, and the flavor of the toothpaste becomes sweeter. Such flavor changes can be perceived by the user and indicate that they have brushed their teeth sufficiently (or insufficiently). User (especially for children)
It is recommended that tooth brushing be continued until the desired flavor change occurs. Therefore, this toothpaste can help develop good toothbrushing habits. The best combinations of acids, flavorings, and sweeteners are malic acid, alginic acid, citric acid, and spearmint, peppermint, clove,
Combinations with mandarin flavoring agents, saccharin and other compatible artificial sweeteners. However, other combinations are within the scope of the invention, preferably in a given order of the components, and mixtures of the components can also be used. Although the present invention has been described above with reference to various examples and embodiments thereof, it is not limited thereto, and it will be understood that substitutes and equivalents can be used without departing from the present invention. is clear to those skilled in the art.

[Brief explanation of drawings]

FIG. 1 shows a portion of a collapsible tube containing a pair of separate envelopes containing separate dentifrice portions and terminating at the neck of the tube so that the contents can be dispensed simultaneously in "stripes"; It is an enlarged view with a cross section at the center. FIG. 2 is a partial mid-section view of another dispensing tube separating two dentifrice portions and dispensing them together on a toothbrush to create a striping effect. FIG. 3 is a central cross-sectional view of a portion of another dispensing tube separating separate portions of toothpaste and dispensing them as an attractive striped product. 11, 31, 61: dispensing tube, 17, 1
9: Envelope body, 23, 63: Toothpaste first part, 25:
Toothpaste second part, 27, 39, 77: threaded collar, 29, 35, 75: neck, 33: adjustment ring, 41: inner container, 51: toothpaste ribbon, 6
1: Internal tube, 69, 71: Hole.

Claims (1)

[Scope of Claims] 1. A container for dispensing ingredients of a toothpaste that does not foam when extruded from the container onto a toothbrush, but foams in the mouth while brushing teeth, in two separate toothpaste parts. comprising a first portion and a second portion; both portions being stably maintained separately and substantially without contact with each other in separate portions of the toothpaste container prior to extrusion; can be dispensed together from a container without substantially foaming until used for brushing teeth in the oral cavity; and a viscous, water-miscible polyol humectant and a gelling or thickening agent in an amount sufficient to impart paste consistency, texture, and non-viscosity to the first portion; at least about 15% by weight; of sodium bicarbonate; and about 1 to 30% by weight of a water-insoluble tooth polishing agent that is non-reactive with the sodium bicarbonate;
the water-insoluble abrasive is selected from the group consisting of calcium carbonate, silica, alumina, silica including bound alumina, zirconium silicate, and mixtures thereof, and serves to stabilize the sodium bicarbonate during storage; a vehicle comprising a liquid selected from the group consisting of water, a viscous, water-miscible polyol humectant, and a mixture of water and a polyol humectant;
and a pH of approximately 1.5 in water at concentrations within the range of 0.5-10%.
~5.5 and comprising about 1-20% by weight of the second portion of an acidic compound that, when in contact with the sodium bicarbonate, can react with it and effervesce with the formation of _CO2 , the acidic compound comprising alginic acid, alginic acid, citric acid,
selected from the group consisting of malic acid, succinic acid, lactic acid tartaric acid, phosphoric acid, acidic phosphate, acidic pyrophosphate, potassium bitartrate, and acidic sodium citrate. 2. A collapsible tube having separate compartments terminating in the tube neck for two toothpaste components; a collapsible tube having separate compartments terminating in the tube neck for two toothpaste components; The container according to claim 1, comprising a gelling or thickening agent. 3. A container according to claim 2, having a structure such that, upon extrusion, the toothpaste has a striped appearance, and the first and second toothpaste parts have a separate appearance. . 4 The weight ratio of the first part and the second part is 0.5:
Claim 1, which is within the range of 1 to 40:1.
Containers listed in section. 5 The weight ratio of the first part and the second part is 0.7:
Claim 1, which is within the range of 1 to 20:1.
Containers listed in section. 6. A first part of the toothpaste contains about 15-50% by weight of sodium bicarbonate, a second part contains about 2-15% by weight of said acidic compound, and the weight ratio of said first part to said second part is A container according to claim 1, wherein the ratio is within the range of 0.8:1 to 5:1. 7. The first part of the toothpaste contains about 20-40% sodium bicarbonate, the second part contains about 4-10% of the acidic compound, and the weight ratio of the first part to the second part is about 1. :1, and the dispensed toothpaste has a striped appearance. 8. The container of claim 2, wherein each of the first part and the second part of the toothpaste comprises silica with abrasive alumina as a water-insoluble tooth abrasive. 9. The container according to claim 1, wherein the acidic compound is malic acid. 10. The container according to claim 1, wherein the acidic compound is alginic acid. 11. The container according to claim 1, wherein the acidic compound is citric acid. 12. The container according to claim 1, wherein the acidic compound is malic acid and the abrasive is calcium carbonate. 13. The container according to claim 1, wherein the acidic compound is citric acid and the abrasive is calcium carbonate.