JP7103670B2 - Intraocular lens - Google Patents

Description

The present disclosure relates to an intraocular lens for implantation in the eye.

Currently commonly used surgical procedures for treating cataracts include implanting an intraocular lens (IOL) into the eye. In such procedures, the normal human crystalline lens, which is clouded by cataracts, is generally replaced by an IOL.

Many breakthrough changes in cataract surgery over the last 40 years have resulted in reliable surgical procedures that regularly produce good treatment results for patients. Modern surgical techniques have also made surgery very safe when performed by a competent surgeon.

Currently, the procedure can also be considered a surgical tool for treating myopia, hyperopia or astigmatism, as an IOL with the appropriate power to provide optical correction can be inserted into the eye.

One of the remaining problems to be solved is to make the distance vision of the naked eye after surgery (eg, without spectacles or contact lenses) more accurate than it is now. In that case, this procedure, as far as naked-eye vision is concerned, makes lens surgery comparable to corneal surgery, general surgical cataract surgery or removal of the clear lens, refractive lens surgery. ).

Recently, lenses have been developed to treat presbyopia. There are two types, multifocal and adjustable. Because the light that enters the eye has more than one focal point, patients transplanted with a multifocal lens have less than half the light that is in focus at one time, resulting in halo, glare, blurred vision and contrast. There is a problem with reduced sensitivity. Many of these lenses needed to be explanted due to these problems. An adjustable lens designed to move forward when the ciliary muscle contracts by looking closer has also been invented. The near vision with these lenses is not as good as the near vision with multifocal lenses, but it does not have the problems associated with multifocal lenses.

Two of the remaining problems to be solved are to make the distance vision of the naked eye more accurate after surgery than the current state, and to use a single focus lens to improve the distance vision and near vision with the naked eye. , And an intermediate vision between them. Therefore, this makes crystal surgery comparable to corneal surgery as far as naked-eye vision is concerned, making general surgical cataract surgery or clear crystal removal safer than refractive surgery of the cornea and seniotomy of the cornea. Use refractive surgery with few complications.

The various embodiments described herein, more accurately, in more consistent, repeatable and predictable locations along the optical or visual axis of the eye, as compared to other lens designs. It comprises an intraocular lens structure in which the optical components of the intraocular lens are arranged, which makes postoperative naked eye vision more predictable (eg, without spectacles or contact lenses).

The present disclosure describes, for example, an intraocular lens that includes rigid haptics connected to foldable optics. Proper connection of foldable optics to hard tactile components causes the tactile components to deform when subjected to the action of the ciliary muscle after implantation into an empty capsular bag during cataract surgery. Can be suppressed. In the various embodiments described herein, two rigid tactile components of substantially equal length were present when placed in the capsular bag during surgery along the optical or visual axis of the eye. It is designed to roughly place the lens optics in the same position as. The lens may be designed to be slightly longer or shorter than the capsular bag, or it may be designed to be flat, curved, or angled. Therefore, the tactile component in some embodiments has a fixed angle between 5 and 40 degrees with respect to the optical component at the time of manufacture, and the lens optical component is moved forward or backward when inserted into the capsular bag. It can be bent into an arch shape.

Accordingly, various embodiments relate to non-adjustable intraocular lenses having at least one hard tactile component connected to a soft optical component. The rigid structure is rigid in the longitudinal direction and soft in the lateral direction. The longitudinal length of the intraocular lens is fixed prior to insertion into the eye. The at least one tactile component can be directly connected to the optics when the lens is manufactured as a single unit, or indirectly connected to the optics by a short extension of the optics.

In any of the non-accommodative lens embodiments described herein, the force of the ciliary muscle may be insufficient to move the optics, for example, forward. For example, in various embodiments, any soft connection (eg, a hinge, torsion bar, etc.) that allows the optical component to be moved relative to the tactile component by the movement of the ciliary muscle is made into the tactile component and the optical component. Do not have between.

Longitudinal rigid tactile components contain the same materials as soft optics and can be manufactured integrally, and tactile components are made rigid by increasing their thickness and / or width thereof. Rigid tactile components can be stiffened by a rigid structure that has a chassis (or frame) that is partially or completely embedded in the soft material of the optics, such as silicone or acrylic. The rigid material of the chassis is designed to stiffen the tactile components and to secure the lens within the lens capsule of the eye. The internal chassis extends tangentially from the lateral side of the chassis tip, using a soft loop (open loop or closed loop) adjacent to the internal chassis, and within the diameter of the optics. It can be done by at least one of creating an open space in the optics, or by a closed loop that extends beyond the diameter of the optics. The loop may be rigid or compressible. For example, these loops may be configured to remain fixed length regardless of ciliary muscle contraction or fibrosis.

In any of the aspects of the intraocular lens described herein, including those described above, the rigid structure may include at least one strut extending in the longitudinal direction. In certain embodiments, the rigid structure at least partially extends at least one strut extending in the longitudinal direction so as to form at least one open area (eg, one, two, or three open areas). Can include a closed structure surrounding the. In certain embodiments, the loop structure may include a first width and a second width. The first width can be closer to the tip of the loop structure and the first width can be wider than the second width. In certain embodiments, the loop structure may have a width narrower than the width of at least one strut extending in the longitudinal direction. For example, the width of the loop structure can be at least one of less than about 25% and more than about 5% of the width of at least one column extending in the longitudinal direction (eg, less than 20%, less than 15%, etc.). Or it can be less than 10%).

In any of the aspects of the intraocular lens described herein, including those described above, the rigid tactile component has a T-shaped soft finger at the tip of the tactile component that is otherwise rigid. You may.

In any of the aspects of the intraocular lens described herein, including those described above, the rigid structure may be a plate-type tactile component. The plate-type tactile component may include a thin bar located at either the tip or proximal end of the tactile component. In addition, the plate-type tactile component may include an open area towards the proximal end of the thin bar.

In any of the aspects of the intraocular lens herein, including those described above, the optics can be in one plane or tilted posteriorly or anteriorly during manufacture prior to insertion into the eye. Can be placed. The structure may also have a fixed length that can withstand deformation due to the action of the ciliary muscle.

Accordingly, various embodiments disclosed herein may have an intraocular lens comprising a soft optical component and at least one tactile component connected to the optical component. At least one tactile component comprises a rigid structure. The intraocular lens comprises a non-adjustable IOL with a fixed longitudinal length.

Various embodiments have an intraocular lens comprising a soft optic and at least one tactile component connected to the optical component, the hard optic component being harder than the soft optic component. In such embodiments, the intraocular lens may include a non-adjustable IOL.

Various embodiments include an intraocular lens, in which the soft optics may be connected to a tactile component of the same material, the tactile component expanding or thickening the structure of the tactile component. , Or by a combination of spreading and thickening, it may be made rigid. In some embodiments, the intraocular lens comprises the same material as a whole (eg, acrylic). In some embodiments, the intraocular lens comprises a monolithic structure.

As mentioned above, in any of the non-accommodative lens embodiments described herein, the force of the ciliary muscle may be insufficient to move the optics, for example, forward. For example, in various embodiments, any soft connection (eg, a hinge, torsion bar, etc.) that can move the optics relative to the tactile component in response to the movement of the ciliary muscle is made into the tactile and optics. Do not have between.

A particular aspect of the present disclosure relates to a non-accommodative single focus intraocular lens configured to provide naked eye vision at all distances. The lens has optical components including tactile components and semi-rigid acrylic, which can be deformed for implantation into the eye through a small incision, but its optical properties and physical properties after implantation into the eye. It can regain its properties and withstand deformation when force is applied by the ciliary muscles and fibrosis.

A particular aspect of the disclosure relates to an intraocular lens having a single focus acrylic optic and at least one semi-rigid acrylic haptic component connected to the optic. The intraocular lens may have a fixed longitudinal length (eg, the same fixed length before and after surgery). Intraocular lenses are resistant to deformation, for example, after implantation into the eye using the semi-rigid tactile components described herein, regardless of contraction and relaxation of the ciliary muscles and fibrosis within the lens sac. Can withstand. The intraocular lens is soft enough to be compressed from its original configuration to a compressed configuration for insertion into the eye through a small incision, and after implantation into the eye, it has a normal shape (eg, an uncompressed shape). ) Can be returned.

In some embodiments, the intraocular lens described above may be configured to provide naked eye vision at short, intermediate, and long distances.
In any of the aspects of the single focus intraocular lens described herein, including those described above, the optics may be positioned at a fixed angle and tilted posteriorly with respect to the tip of at least one tactile component. .. The tilt can remain unchanged after implantation into the eye. Moreover, in some embodiments, the valve angle can remain unchanged after implantation into the eye. In certain embodiments, the at least one tactile component may be placed tilted forward. In certain embodiments, the at least one tactile component comprises two tactile components, both of which can be tilted forward. In certain embodiments, the vault angle can be from about 1 degree to about 50 degrees.

In any of the aspects of the single focus intraocular lens described herein, including those described above, the semi-rigid tactile component may include at least one strut extending in the longitudinal direction. In certain embodiments, the rigid structure at least partially extends at least one strut extending in the longitudinal direction so as to form at least one open area (eg, one, two, or three open areas). Can include a closed structure surrounding the. In certain embodiments, the loop structure may include a first width and a second width. The first width can be closer to the tip of the loop structure and the first width can be wider than the second width. In some embodiments, the width of the loop structure may be shorter than the width of at least one longitudinally extending strut. For example, the width of the loop structure can be at least one of less than about 25% and more than about 5% of the width of at least one strut extending in the longitudinal direction (eg, less than 20%, less than 15%, etc.). Or it can be less than 10%).

In any of the aspects of the single focus intraocular lens described herein, including those described above, the semi-rigid tactile component is a T-shaped tactile sensation at the tip of the tactile component that is otherwise semi-rigid. It may have a compressible soft lateral finger to make up the part.

In any of the aspects of the single focus intraocular lens described herein, including those described above, the semi-rigid structure can be a plate-type tactile component. The plate-type tactile component may include a soft, thin tip lateral finger that forms a T-shaped tactile component.

In any of the aspects of the single focus intraocular lens described herein, including those described above, the semi-rigid tactile component may be harder than the soft optical component. The optics are inserted into the eye through a small incision having a length of about 3.0 mm or less, preferably about 2.5 mm or less, because the optics can be soft at their thin perimeter and semi-rigid at their center. The optical components can be folded into a vertically long structure.

In various embodiments, the intraocular lens can be a non-adjustable IOL. In certain embodiments, the non-accommodative IOL is designed to provide far vision, intermediate vision and near vision. In certain embodiments, this non-accommodative IOL provides such vision without the glare, halo and blurred vision, and reduced contrast problems experienced with multifocal intraocular lenses.

In any of the aspects of the monofocal intraocular lens described herein, including those described above, a rearwardly arched optical component is connected to a tactile component of the same semi-rigid material. Tactile components are constructed to be stiffer by expanding or thickening the structure, or by combining expanding and thickening.

Some aspects of the disclosure relate to a non-accommodative intraocular lens having a single focus optical component and at least one semi-rigid tactile component connected to the optical component. The optics can be arched (eg, posteriorly) at a fixed angle to at least one tactile component prior to surgery. The optics may remain arched after implantation and, in some embodiments, the vault angle may remain unchanged after implantation. The semi-rigid tactile component is soft enough to be compressed for insertion into the eye through a small incision, and can take its usual uncompressed shape after implantation into the eye. In some embodiments, the lens may be configured to provide unaided vision at short, medium, and long distances.

In any of the non-adjustable intraocular lenses described herein, including those described above, at least one semi-rigid tactile component can be placed tilted forward. In certain embodiments, the at least one semi-rigid tactile component comprises two tactile components, both of which are tilted forward.

In any of the non-adjustable intraocular lenses described herein, including those described above, the vault angle can be from about 1 degree to about 50 degrees, for example from about 5 degrees to about 40 degrees.
In any of the non-adjustable intraocular lenses described herein, including those described above, the optics and at least one tactile component may include the same material (eg, acrylic or silicone). A particular aspect of the disclosure relates to the implantation of a non-adjustable intraocular lens having an optical component connected to at least one tactile component. The intraocular lens may have any of the features described herein. Prior to surgery, the intraocular lens can be arched posteriorly at a fixed angle to at least one tactile component. The intraocular lens can be compressed for insertion into the eye through a small incision. After implantation, the intraocular lens is normally uncompressed, with sufficient resistance to withstand pressure changes in the eye, such as pressure changes in the eye due to ciliary muscles trying to adapt or due to fibrosis. Can take shape. After implantation, the intraocular lens can remain arched and, in some embodiments, may remain arched at the same fixed angle.

A particular aspect of the disclosure relates to a non-adjustable intraocular lens having a single focus acrylic optical component and at least one tactile component connected to the optical component. The optics can be arched at a fixed angle to at least one tactile component prior to surgery. The optics can remain arched after implantation and, in some embodiments, the vault angle can remain unchanged after implantation. In some embodiments, the intraocular lens may be configured to provide unaided vision at short, intermediate, and long distances.

In any of the non-adjustable intraocular lenses described herein, including those described above, at least one tactile component can be placed tilted forward. In certain embodiments, at least one tactile component may include two tactile components that are tilted forward.

In any of the non-adjustable intraocular lenses described herein, including those described above, the vault angle can be from about 1 degree to 50 degrees, such as from about 5 degrees to about 40 degrees.
In any of the non-adjustable intraocular lenses described herein, including those described above, the optics and at least one tactile component may include the same material.

A particular aspect of the present disclosure relates to an adjustable intraocular lens comprising a lens optic and a pair of opposing plate-type tactile components coupled to the lens optic. Each plate-type tactile component may include a rigid frame that is at least partially embedded in a soft component. The rigid frame may include a number of openings along the tip of the frame. At least some at least a portion of the opening may extend beyond the tip edge of the soft component. The cross-sectional width of the hard frame measured between the opposing lateral edges of the hard frame can be wider than the cross-sectional width of the soft component measured between the opposing lateral edges of the soft component. The rigid frame can extend beyond the proximal edge of the soft component.

In any of the adjustable intraocular lenses described herein, including those described above, each plate-type tactile component may include a connecting portion connected to an optical component. The connecting portion may include a short appendage connected to the optical component and at least one connecting bar extending laterally from the short appendage. At least one connection bar may include a first connection bar and a second connection bar. The first and second connection bars may extend laterally from opposite sides of the short appendage.

In any of the adjustable intraocular lenses described herein, including those described above, each plate-type tactile component may include an elongated slot.
In any of the adjustable intraocular lenses described herein, including those described above, each plate-type tactile component may include at least one anterior projection extending anteriorly from the plate-type tactile component.

In any of the adjustable intraocular lenses described herein, including those described above, each plate-type tactile component may include opposing lateral paddles. The transverse width measured between the outer lateral edges of the opposite paddles of the same tactile component can be greater than the transverse width of the optical component.

A particular aspect of the present disclosure relates to an adjustable intraocular lens comprising a lens optic and a pair of opposing plate-type tactile components coupled to the lens optic. Each plate-type tactile component may include a rigid frame with a number of openings.

In any of the adjustable intraocular lenses described herein, including those described above, the rigid frame is at least partially embedded in the soft component. In some embodiments, the rigid frame may include a number of openings along the tip of the frame. In various embodiments, at least some of at least some of the openings can extend beyond the tip edge of the soft component. In some embodiments, the rigid frame extends beyond the proximal edge of the soft component.

In any of the adjustable intraocular lenses described herein, including those described above, the transverse width of the rigid frame measured between the opposing lateral edges of the rigid frame is the opposing lateral width of the soft component. Wider than the cross-sectional width of the soft component measured between the edges.

In any of the adjustable intraocular lenses described herein, including those described above, each plate-type tactile component may include a connecting portion connected to an optical component. The connecting portion may include a short appendage connected to the optical component and at least one connecting bar extending laterally from the short appendage. At least one connection bar may include a first connection bar and a second connection bar. The first connection bar and the second connection bar may extend laterally from opposite sides of the short appendage.

In any of the adjustable intraocular lenses described herein, including those described above, each plate-type tactile component may include an elongated slot.
In any of the adjustable intraocular lenses described herein, including those described above, each plate-type tactile component may include at least one anterior projection extending anteriorly from the plate-type tactile component.

Any of the intraocular lenses described herein, including those described above, may include a first plate-type tactile component and a second plate-type tactile component, the first plate-type tactile component. The optical component and the first plate-type tactile component are coupled to the optical component at a non-zero first set angle, and the second tactile component is located between the optical component and the second plate-type tactile component. It is coupled to the optics at a non-zero second set angle, and the non-zero second angle is different from the non-zero first angle. In various embodiments, the lens is configured such that when the lens is placed in the capsular bag of the eye, the upper hemisphere of the optic is in the 12 o'clock position and is positioned posteriorly with respect to the lower hemisphere. Will be done. In some embodiments, the upper hemisphere is configured to focus light for distance vision. In certain embodiments, the non-zero first angle is greater than or equal to 10 degrees and less than or equal to 50 degrees. Similarly, in certain embodiments, the non-zero second angle is at least about 20 degrees and about 50 degrees or less.

Also, in any of the intraocular lenses described herein, including those described above, the optical component may be a progressive power lens that includes an increasing power gradient, eg, when implanted in the eye. , The upper hemisphere of the optical component may provide far vision and the lower hemisphere of the optical component may provide near vision.

A wide variety of variants are possible. For example, any feature, structure, or step disclosed herein may be replaced, combined, or omitted with any other feature, structure, or step disclosed herein. Can be done. In addition, to summarize the disclosure, this specification has described certain aspects, advantages, and features of the invention. It should be understood that according to any particular embodiment of the invention disclosed herein, one or all such advantages are not necessarily achieved. Aspects of the present disclosure are neither essential nor essential.

The various embodiments are shown in the accompanying drawings for illustration purposes and are not to be construed as limiting the scope of the embodiments. Moreover, the various features of the different disclosure embodiments can be combined to form additional embodiments that are part of the present disclosure.

A non-adjustable lens having a loop (eg, an open loop) comprising an optical component that can be arched rearward and an integral tactile component containing, for example, acrylic as one material is shown. Tactile components are wider and can be manufactured flatter than traditional looped tactile components. Shown is a non-accommodating intraocular lens (NAIL) of a plate-type tactile component with a small fixed loop, all made integrally. The optics can be arched backwards. Embodiments of a tactile component comprising a single rigid longitudinal structure having a T-shaped soft tip lateral extension. Shown is a non-adjustable intraocular lens (NAIL) with a chassis embedded in the same soft material as the optics. It is the same as FIG. 4, but there is no fixed loop. Two exposed rigid longitudinal plates or struts, connected by a thin crossing bar to create an enclosed open space, and a fixed loop (eg, an open loop) that facilitates fixation of the lens into the capsular bag. Shows another NAIL with. The lens may be designed without soft fingers, as fixation can occur over the narrow transverse bar 9. The width of the thin arm 9 can be shorter than the width of the vertical plate or column 7. Shows yet another NAIL with longitudinal plates or struts connected by thin crossing bars, but without fixed loops. Another embodiment of a tactile component having a two-loop structure of a rigid tactile component is shown. Shown is an intraocular lens of a hard tactile component with a three-loop structure, the three loops (eg, closed loops) are partially coated with the same soft material as the optical component. Shown is an intraocular lens of a hard tactile component with a three-loop structure, the three loops (eg, closed loops) are partially coated with the same soft material as the optical component. Shown is an intraocular lens of a hard tactile component with a three-loop structure, the three loops (eg, closed loops) are partially coated with the same soft material as the optical component. Shown is an intraocular lens of a hard tactile component with a three-loop structure, the three loops (eg, closed loops) are partially coated with the same soft material as the optical component. A side view of the optical component of the intraocular lens, which is bent rearward in an arch shape, is shown. A side view of the optical component of the intraocular lens bent forward is shown. A side view of an intraocular lens having tactile components arranged on a common plane is shown. FIG. 5 is a schematic diagram showing a lens including optical and tactile components configured in an extended "z" shape. FIG. 6 is a schematic showing how long-distance, short-distance, and intermediate-distance focusing can be achieved on the retina by tilting the optics. A schematic view of an intraocular lens implanted in the capsular bag is shown. A schematic diagram of an embodiment of an adjustable intraocular lens having a closed-loop tactile component is shown. A schematic diagram of an embodiment of an adjustable intraocular lens having a closed-loop tactile component is shown. A schematic diagram of an embodiment of an adjustable intraocular lens having a closed-loop tactile component is shown. A schematic diagram of an embodiment of an adjustable intraocular lens having a closed-loop tactile component is shown. Demonstrating an embodiment of a tactile component having a single thick, rigid longitudinal tactile component structure, the tactile component structure is tilted forward or bent into an arch and is T-shaped soft. It has a tip lateral extension. Another lens design with two thick rigid longitudinal plates or struts 7 connected by a thin crossing bar 9 is shown, which creates an enclosed open space 12 (eg a closed loop) with a soft, thin tip. Along with the lateral finger 6, it facilitates fixation of the lens into the capsular bag. The lens may be designed without soft fingers, as fixation can occur over the narrow transverse bar 9. The width of the thin arm 9 can be shorter than the width of the vertical plate or column 7. A lens design with a thick longitudinal central plate 20 having a width of less than about 3.0 mm, the plate 20 having two closed loops 21 that provide two open spaces 22 for fixing the lens to the capsular bag. .. A half of a lens comprising a tactile component 1 having a lateral member (or paddle) 30 is shown. The tactile component 1 can be wider than the optical component 2, and the tip 31 of the lateral member 30 can be designed to be posterior to the optical component after implantation. The tactile component 1 constitutes a closed loop 12. A half of a lens comprising a tactile component 1 having a lateral member 30 is shown. The tactile component 1 can be made wider than the optical component by the finger-like soft lateral extension 6.

Many intraocular lenses have optics connected to two or more soft tactile components that serve to center and secure the lens in the empty capsular bag of the human lens. These tactile components can be formed by two soft loops.

The circular ciliary muscles inside the eye, which are part of the autonomic nervous system and are active throughout life, are involved in the activity of changing the focus of the eye. When a patient transplanted with a standard loop intraocular lens attempts to see early after cataract surgery, the still active ciliary muscles (eg, in the longitudinal direction of the lens) end-end pressure. This pressure acts on the soft loop to move the soft loop anteriorly, posteriorly, centrally and peripherally within the ciliary sac. This movement can shift the position of the lens within the lens capsule. Fibrosis also occurs during this period, and the loop is not necessarily fixed to the cul-de-sac of the capsular bag that was placed at the time of surgery. Instead, the loop can be fitted, for example, somewhere between the capsular sac and the optics. By repositioning the loops of the tactile optics within the lens capsule, the position of the lens optics can also be repositioned along the axis of the eye, which can result in eccentricity and tilting of the optics. In some soft loop designs, the thin, flimsy soft loops at the time of manufacture are significantly longer than the 10 mm diameter of the lens capsule (eg, up to 12 mm in length) and act through the lens capsule wall to be ciliary. It may act on the body muscles. The tactile component can be thin and light and can be easily deformed by the pressure applied to the tactile component early after surgery. Therefore, the position of the lens is not at the position that would be calculated and predicted. Therefore, far vision and postoperative refractive power with the naked eye (eg, without spectacles or contact lenses) are not what would be expected before surgery. In some cases, the lens loop is centrally compressed to be located anterior or posterior to the lens optics.

The various embodiments described herein make the eye more consistent, repeatable and predictable, along the optical or visual axis of the eye, as compared to other lens designs. It comprises an intraocular lens structure in which the optics of the inner lens are placed, which makes post-operative naked eye vision more predictable (eg, without spectacles or contact lenses).
Non-adjustable lens See, for example, the intraocular implants shown in FIGS. 1-4. The intraocular implant comprises an optical component 2 and an opposing rigid tactile component 1 (eg, a plate-type tactile component) and selectively has a soft loop lateral extension 6 (eg, open loop) (FIG. 3 and). (See FIG. 4). However, FIGS. 4 to 8 show only one of the two tactile components. The tactile component 1 can be directly connected to the optical component 2 (see FIGS. 1 and 2) or to the short, thick rigid extension 3 of the optical component 2 (see FIGS. 3-8). It can be configured as a single unit (eg, monolith) at the time of manufacture, or it can be formed separately and connected together. The short extension 3 can be made of the same material as the optical component 2. Further, the short rigid extension 3 can be integrally molded with the optical component 2 or formed separately from the optical component 2. For ease of connection, holes 8 are created through the hard components of the tactile component, through which the soft components 103 or the hard extension 3 can be fused and integrated during the manufacturing process. Yes (see FIGS. 3-8). A short and thick rigid extension 3 may be desired to facilitate the connection between the optical component 2 and the tactile component 1 without penetrating onto the outer circumference of the optical component 2.

The optics 2 may comprise a substantially transparent biocompatible soft optical material such as acrylic, hydrogel, or silicone, and the optics 2 may be biconvex, plano-convex, concave / flat, annular, aspherical. , Or a spherical Frenel type multifocal or any combination thereof. The optical component 2 may be a progressive power lens that includes an increasing power gradient, for example, when implanted in the eye, provides far vision in the upper hemisphere of the optical component and near vision in the lower hemisphere of the optical component. May bring. The optical component 2 may be used in combination with a second optical component in the eye.

The tactile component 1 may be designed to be rigid and resistant to deformation by the action of the ciliary muscle. In particular, the tactile component may be resistant to the pressure exerted in the longitudinal direction by the ciliary muscle without bending. Unlike the soft tactile components traditionally used with non-adjustable and adjustable lenses, the hard tactile component 1 is resistant to compression, so that the hard tactile component 1 is opticed. ) Is made easier and the optical components are placed in a more consistent position along the axis of the eye.

As shown in FIG. 1, in some embodiments, the tactile component 1 may include an open loop. Some tactile components 1 may include one or more closed loops (see also FIGS. 6-9, which are more fully described below).

FIG. 1 shows a lens made of, for example, acrylic as an integral form, with the optical component 2 adjacent to a curved open loop such as the rigid tactile component 1. As with all these lens designs, the lens may be in one plane, or the optics 2 may be arched posteriorly or anteriorly during surgery.

FIG. 2 shows a lens made of one material (eg, acrylic) with a rigid plate-like tactile component structure 4'and a small tip-fixing finger 5.
FIG. 3 schematically shows an embodiment of a tactile component 1 having a single hard vertical structure 11 and forming a T-shape by the structure 11 and a soft tip lateral extension portion 6. The rigid longitudinal structure 11 is attached to or connected to the short and thick extension 3 of the optical component 2.

4 and 5 show tactile component 1 comprising a chassis 104 including two rigid stanchions / plates 101 and a proximal transverse connection bar 102 (at its proximal end) between the two stanchions / plates 101. .. The chassis 104 embedded in the soft optical material 103 has an external tip fixing finger 6 in FIG.

FIG. 6 shows a tactile component 1 including two rigid struts / plates 7, where the rigid struts / plates include a finger-like extension 6 with a peripheral end 10 such as a knob during the manufacturing process. , It is embedded in the thick hard extension portion 3 of the optical component 2 in the proximal direction, or the soft material is melted and integrated through the hole 8 to be fixed and connected to the optical component. The two plates 7 are connected at the tip by a narrow crossbar 9. The two rigid columns / plates 7 and the transverse crossbar 9 form a longitudinally open space between the transverse crossbar 9 and the optical component 2.

FIG. 7 covers the upper side of the thin tip connecting bar 9 to fuse the anterior and posterior capsules so as to form fibrous tissue through an open space 12 surrounded by struts / plates 7, bars 9 and a thick rigid extension 3. This is similar to FIG. 6 except that fixation into the lens capsule is achieved without the soft finger 6. The width of each strut can be 1.0-3.0 mm so that the lens can be folded vertically to be compressed to be inserted through an incision of 3.0 mm or less.

FIG. 8 shows a tactile component 1 containing a single plate 20, with two rigid closed loops 21 attached to each of the side surfaces of the plate 20, the capsular bag forming fibrous tissue, and the lens tactile component 1. Provides two enclosed spaces 22 or openings in which the lens can be secured within the capsular bag.

10, 11, and 12A show a possible side view of the lens, which can be arched rearward (FIG. 10) and arched forward (FIG. 11). Can be on one plane (Fig. 12A). 10 and 11 show an optical component that is arched posteriorly and anteriorly with respect to the tip of the tactile component during implantation, respectively. The lens shown in FIG. 10 may include, for example, a one-plane adjustable lens as described herein that is arched upon implantation. As described herein, the lens shown in FIG. 10 may also be manufactured with the tactile component tilted (eg, forward) relative to the optical component to increase the depth of focus. good. The optics may be in a suitable position to increase the depth of focus as the optics are arched rearward with respect to the tip of the tactile component.

In another embodiment, as shown in FIG. 12B, each of the tactile components can be tilted or fixed in different directions so that the lens forms an outwardly extended z-shape, eg, an optical component. On the other hand, for example, the first tactile component can be arranged or fixed tilted forward, and the second tactile component can be arranged or fixed tilted backward. Each of the tactile components can be tilted or fixed at a non-zero angle to the optics. The first tactile component can be tilted or fixed at a non-zero first angle, and the second tactile component is at a non-zero second angle that is different from the non-zero first angle. It can be tilted or fixed. With the tactile components tilted in different directions, the optics can be tilted as shown in FIG. 12C so that the upper hemisphere of the optics tilts backwards when the lens is placed in the lens capsule. The lower hemisphere of the optical component is tilted forward. In this configuration, when implanted in the eye, the upper hemisphere can be positioned to improve far vision, while the lower hemisphere can be positioned to improve near vision. Such a tilted arrangement is described in US Patent Application Publication No. 13/935,605 (Agent Reference Number CORD.005C1) published as US Patent Application Publication No. 2014/0172093A1. , The whole of which is incorporated herein by reference.

FIG. 13 shows a schematic view of the non-accommodative intraocular lens 100 in the lens capsule. The anterior sac 50, the posterior sac 51, and the anterior sac 52, which is a blind sac of the capsular bag inside, are shown.
The lens described above is designed to have a soft optical component 2 connected to a hard tactile component 1 (eg, a plate-type tactile component) that is rigid in the vertical direction but soft in the horizontal direction. Can be compressed into an insertion device to be inserted into the eye through an incision of 3.0 mm or less. The tactile component 1 is rigid enough to prevent longitudinal bending when subjected to the pressure exerted by the action of the ciliary muscles and fibrosis. The narrow transverse connection bar 9 of the chassis 104, when present, is soft so that the lens can be folded and compressed around the vertical axis.

In various embodiments, the overall length D of the lens 100 may be from about 9.5 mm to about 14.0 mm when measured diagonally from the tips of the fixed lateral loops 6 on either side of the lens 100. See, for example, FIGS. 3 and 13. The diagonal distance D extends through the center of the optical component 2. The longitudinal length L of the lens 100 (also shown in FIGS. 3 and 13) can be at least the diameter of the average capsular bag. For example, the longitudinal length of the lens 100 can be from about 9.5 mm to about 12.0 mm, with a preferred length of about 10.5 mm in various embodiments, which is specific. Slightly longer than the average capsular sac diameter in the embodiment. When the length of the lens 100 is about 10.5 mm or less, the lens 100 does not deform the capsular bag and does not act on the ciliary muscle.

The tactile component component 3 extending from the soft optical component 2 is rigidly constructed in some embodiments by its short length of less than 1 mm and thickness of more than 1 mm, and is at least a portion of the component 3. May include acrylics, silicones or other inert soft materials, and hard components, polyimides, acrylics or other hard materials. In some embodiments, the tactile component 1 may be configured to be rigid in the vertical direction, provided that it is a combination of hard materials 104 embedded within the soft material 103. At least one of the rigid struts and the plate 7 is a polyimide, a proline, or any derivative of a nylon, PMMA titanium, other rigid material, or an inert material, so as to make the tactile component 1 longitudinally rigid. Alternatively, it may include a combination of a hard material and a soft material.

In some embodiments, the intraocular lens may include at least one (eg, two, three, or more) semi-rigid tactile components and an optical component. In some embodiments, the at least one semi-rigid tactile and optical component may comprise the same material (eg, acrylic). In some embodiments, the intraocular lens can be a monolith or a single body. The semi-rigid tactile and optical components may be foldable for inserting the optical components into the eye through a small incision. However, after insertion and regaining its shape, it is sufficiently resistant to the pressure changes in the eye caused by the contraction and relaxation of the ciliary muscles and the forces generated during postoperative fibrosis. Have. The lengths of the two semi-rigid tactile components can be equal. The action of the ciliary muscle and its resistance to fibrotic deformation are substantially the same along the optical or visual axis of the eye, as when the lens optics were placed in the empty capsular bag during surgery. Leave in. For example, in order to achieve the optimum depth of focus, the lens may be designed to be slightly longer or shorter than the capsular bag, and the tactile component (eg, the tip of the tactile component) is about 1 at the time of manufacture. For optical components at fixed angles between degrees to 50 degrees, for example about 5 degrees to about 40 degrees (eg, about 5 degrees to about 20 degrees, about 10 degrees to about 25 degrees, or about 15 to about 40 degrees). It may be angled with respect to it. As a result, the lens optical component is positioned posteriorly to the tip of the tactile component when it is inserted into the capsular bag.

Various embodiments relate to non-adjustable intraocular lenses having optics manufactured integrally, with the optics tilted rearward with respect to the tip of the tactile component or bent into an arch. , Tilt angle or vault angle may be the same at both optics / tactile component joints. The semi-rigid lens structure can withstand deformation due to ciliary muscles and fibrosis, but can be folded vertically to allow insertion into the capsular bag of the eye through an incision less than 4.0 mm. can.

The total length of the lens in the longitudinal direction can be about 9.5 to about 12 mm, and the length may be slightly longer than the capsular bag, preferably about 10.5 mm. When the length of the lens 100 is about 10.5 mm or less, the lens 100 does not deform the capsular bag and does not act on the ciliary muscle.

Both semi-rigid tactile components can be of the same length. The diameter of the optical component can be 4.0 to 8 mm, and the thickness of the thin center can be about 0.2 to about 2.0 mm. Since the semi-rigid material withstands deformation due to ciliary muscles and fibrosis, the tactile component cannot be significantly deformed and therefore the lens optics are in the same position after surgery as they were at the time of surgery. Similarly, the orientation of the intraocular lens after surgery can be the same as before surgery, along the axis of the eye and on the axis of rotation on which the annular lens should be implanted. This makes the predictability of the postoperative effective lens position (ELP) along the visual axis of the eye more accurate, and therefore the naked eye visual acuity becomes more predictable. The longitudinal length of the intraocular lens can be fixed prior to insertion into the eye, for example the longitudinal length of the intraocular lens can be the same preoperatively and postoperatively. However, the lens may have a thin, soft tip lateral finger to produce a lateral diameter longer than the longitudinal diameter. These soft fingers can be designed to secure the lens within the lens capsule and prevent rotation of the lens when the annular optics are part of the lens design.

As mentioned above, the longitudinal hard tactile component can have the same material as the soft optical component and can be manufactured as an integral part. Semi-rigid tactile components can be constructed more rigid by increasing at least one of their thickness and width. For fixation, use a soft loop (open loop or closed loop) continuous with the lens body extending tangentially from the lateral side of the tip of the plate-type optic component design, or open space within the diameter of the haptic component. It can be done by making, as well as by at least one of the closed loops extending beyond the diameter of the optics. The loops of the semi-rigid material may be soft and thin enough to be compressed, but may be hard enough to maintain the length of the lens when receiving force from the ciliary muscles.

However, the various embodiments disclosed herein can address the problems described above. See, for example, the intraocular implant shown in FIG. The intraocular implant includes an optical component 2 and a semi-rigid tactile component 1 that is tilted forward and is arranged, the semi-rigid tactile component 1 being bent with a soft loop lateral extension 6 (eg, an open loop). It is directly connected to the optical component at the joint 4. 16-18 show only one of the two halves of the lens. The lens can have bi-rotational symmetry and the other half is the same as shown. The short optical component extension 3 may have a rigid bend joint 4 between the optical component 2 and the tactile component 1. The optical component 2 and the tactile component 1 can be made of the same material (eg, acrylic). The short optical component extension 3 may be desired to facilitate the connection between the optical component 2 and the tactile component 1 without the tactile component 1 penetrating onto the outer periphery of the optical component 2. The intraocular lenses of FIGS. 16-18 may include any of the features described in connection with FIGS. 3, 6, and 8. The tactile component 1 does not include a through hole through which the optical component extension 3 can extend, but unlike those figures, these embodiments may also include a through hole. Similarly, any or a combination of features of the embodiments shown in any of FIGS. 15-18 may be included in any of the other lenses shown in FIGS. 1-7. For example, the bend joints 4 shown in FIGS. 15-18 (and 9) can be included in FIGS. 1-2.

The lens may contain a transparent biocompatible soft optical material such as acrylic, and the optics may be biconvex, plano-convex, concave / flat, annular, aspherical, spherical, Fresnel-shaped, multifocal, or. It may be any combination thereof. The optical component 2 may be a progressive power lens that includes an increasing power gradient, for example, when implanted in the eye, it provides near vision to the lower hemisphere of the optical component and far vision to the upper hemisphere of the optical component. Bring.

The tactile component 1 is semi-rigid, at least in the longitudinal direction, and is designed to withstand the action of ciliary muscles or deformation due to fibrosis. Unlike the soft tactile components traditionally used with non-adjustable and adjustable lenses, the longitudinal semi-rigid tactile component 1 is resistant to deformation due to ciliary muscles and fibrosis. Therefore, the semi-rigid vertical tactile component 1 facilitates centering and allows the optical component to be more consistently positioned along the axis of the eye.

In the intraocular lens embodiment described herein, the overall length of the lens 100 is approximately 9. It may be from 5 mm to about 12.0 mm and from about 11.0 mm to about 14.0 mm. See, for example, FIG. The transverse loop 6 may include a directional member 10 at the end of the transverse loop 6 (eg, one at each end of a round or oval knob, fixing member). The diagonal distance extends through the center of the optics. The longitudinal length L of the lens 100 (also shown in FIG. 3) can be at least the diameter of the average capsular bag. For example, the preferred longitudinal length can be about 10.5 mm. When the length of the lens 100 is about 10.5 mm or less, the lens 100 does not deform the capsular bag and does not act on the ciliary muscle.

In some embodiments, the short optic extension 3 extending from the soft optic may be constructed more rigid by its short length of less than 1 mm and its thickness.
As shown in FIG. 18A, the tactile component 1 has a lateral member (or paddle, as referred to elsewhere herein) 30 and a transverse bar 9 extending between the lateral extension members 30. obtain. The tactile component 1 can be wider than the optical component 2 (eg, the lateral distance between the lateral extension members 30 on both sides of the optical component relative to the width or diameter of the optical component), and the lateral member 30 Chip 31 may be designed to be behind the optics at the time of implantation. Therefore, the lateral member 30 can be greatly curved toward the tip 31. The tactile component 1 may form a closed loop 12 (and an open region). The intraocular lens can include a short optical component extension 3, with a hard bend joint 4 between the optical component 2 and the tactile component 1 between both ends of the extension. As described herein, the bend joint 4 allows the tactile component to be tilted at an angle with respect to the optical component during manufacturing. In some embodiments, the tactile component 1 partially surrounds the optical component by more than 180 ° of the outer circumference of the optical component. For example, a single tactile component is at least 110 °, 120 °, 130 °, 140 °, 150 °, 160 °, or 170 ° on the outer circumference of the optical component, up to 175 ° or 180 °, or any between them. Can surround the range of.

As shown in FIG. 18B, the tactile component 1 is a lateral member (or paddle) having an arched outer edge at the tip and an outer edge parallel to the longitudinal length in the proximal direction with respect to the optical component. ) 30 can have. The tactile component 1 can be wider than the optical component by having a finger-like soft lateral extension portion 6. The lateral member 30 can be connected by a short optical component extension 3, and there is a hard bending joint 4 between the optical component 2 and the tactile component 1 between both ends of the extension. In some embodiments, the tactile component 1 partially surrounds the optical component by more than 180 ° of the outer circumference of the optical component. For example, a single tactile component is at least 110 °, 120 °, 130 °, 140 °, 150 °, 160 °, or 170 ° on the outer circumference of the optical component, up to 175 ° or 180 °, or any between them. Can surround the range of.

9A-9D show a non-adjustable IOL with a soft optical component 2 having a hard tactile component 1, which tactile component 1 extends from two laterally extending closed loops 31 in two longitudinal directions. It comprises a chassis 104 with rigid struts / plates 30, and a bi-closed loop is designed to secure and center the lens within the lens capsule. A tip bar 39 extends between the two columns / plates 30 to form a centrally enclosed open area 32. Thus, various embodiments may include one, two, three, four, or more closed loops 31 (and open regions 32), at least a portion of the closed loops 31 due to fibrosis. It may be easy to fix. In some embodiments, as shown in FIGS. 9A-9D, the more central open area 32 is larger than any open area on either side of the central open area. The chassis 104 is partially embedded in the soft material 43 of the optical component. In various embodiments, the tactile component 1 is tilted relative to the optical component 2. The line 107 indicating the rigid bending joint 4 at the base end portion of the frame or chassis 104 indicates an inclined arrangement of the tactile component 1 at an angle with respect to the optical component 2, as described herein. However, in other embodiments, the designs shown in FIGS. 9A-9D do not require the tactile components to be tilted relative to the optics during manufacturing and therefore need to include the rigid bend joint 4 as shown. do not have. The blind sac of the capsular bag 33 is shown partially inflated to a radius of 11.5 mm.
Adjustable Lenses Although some embodiments have been described herein with respect to non-adjustable lenses, tactile components that may be combined with hinges or connecting bars may be used in adjustable lenses.

Various embodiments of the tactile components described herein, including but not limited to those shown in FIGS. 6-9D, can be used in adjustable lenses. Additional information regarding the connection bar and adjustable lens is provided in US Patent Application Publication No. 14/035,821, published as US Patent Application Publication No. 2014/0094909, filed September 24, 2013 ("" Accommodating Intraocular Lens ”(agent reference number CORD.009P1), and US Patent Application Publication No. 2015/0088254, filed September 24, 2013. It can be found in the specification No. 14/03, 813 (“ANTERIOR CAPSULE DEFLECTOR RIDGE”) (agent reference number CORD.010A), which is incorporated herein by reference in its entirety. , Should be considered as part of this specification.

14A-14D show an example of an adjustable intraocular lens 200 having an optical component 202 and an opposing plate-type tactile component 214. The plate-type tactile component 214 may include a frame 222 embedded within a soft component 226. The frame 222 can include a through hole 230, and a soft component 226 can extend through the through hole to fix the frame 222. The frame 222 may include polyimide, prolean, polymethyl methacrylate (PMMA), titanium, or similar material. The soft component 226 may include silicone, hydrogel, acrylic, or similar materials. In some cases, the soft component 226 and the optics 202 may be constructed from the same material, for example acrylic.

As shown in FIG. 14A, the frame 222 may extend outward beyond the proximal and distal edges of the soft component 226. The exposed edges of the frame 222 reduce the slipperiness of the adjustable intraocular lens (AIOL) 200 during implantation, facilitating implantation in the correct position. The frame 222 may include a number of openings 238 (eg, one, two, three, four, or more) at its tip. At least some of the openings 238 may be at least partially configured by a narrow crossing bar 242 positioned at the tip of the tactile component 214. At least a portion of the opening 238 can extend beyond the distal edge of the soft component 226 so that fibrosis occurs around the narrow transverse bar 242 and through the opening 238. Thus, as mentioned above, various embodiments may include one, two, three, four, or more closed loops (and open regions 238), at least a portion of which is fixed by fibrosis. Can be prompted. In some embodiments, as shown in FIGS. 14A-14D, the more central open region 238 is larger than any open region on either side of the central open region.

In the plate-type tactile component 214, the plate-type tactile component 214 is substantially soft in the transverse direction (for example, parallel to the x-axis) and substantially hard in the longitudinal direction (for example, parallel to the y-axis). The plate-type tactile component 214 is soft enough in the transverse direction to facilitate the insertion of the AIOL into the eye, and contraction of the hairy muscles, ie compression between the ends. Can be rigid enough in the longitudinal direction to withstand eccentricity in response to.

The proximal end portion of each plate-type tactile component 214 may include opposing paddles 234 that at least partially surround the optical component 202. In various embodiments, for example, a single tactile component can enclose at least 160 °, 170 ° to 175 ° or 180 °, or any range between them, or optionally optical, the outer circumference of the optical component. At 110 °, 120 °, 130 °, 140 °, or 150 ° of the circumference of the part, it can surround up to 160 °, 170 ° or 180 °, or any range between them. The cross-sectional width measured between the outer lateral edges of the paddle 234 can be greater than the lateral diameter of the optical component 202. The base end portion of the paddle 234 may be separated (eg, separated) from the optics 202. Prior to transplantation, AIOL 202 can be produced in a substantially single planar shape. When the AIOL 200 is implanted in the eye, the optics 202 are arched posteriorly with respect to the tips of the tactile components so that at least the proximal end of the paddle 234 is posterior to the optical component after implantation into the eye. Can turn into. When pushed backwards, the larger surface area of the paddle 234 may further increase the pressure behind the AIOL 200, which facilitates the movement of the optics 202 in the forward direction as the ciliary body contracts. The pressure of the fluid in the vitreous cavity is increased.

Each of the opposing paddles 234 may include at least a portion of the frame 222 and at least a portion of the soft component 226. The portion of the frame 222 that constitutes the paddle 234 can be made larger than the portion of the soft component 226 that constitutes the paddle 234. The portion of the frame 222 forming the paddle 234 can be wider or longer than the portion of the soft component 226 forming the paddle 234. As shown in FIG. 14A, in the paddle 234, the frame 222 extends laterally beyond the lateral edge of the soft component 226 and in the proximal direction beyond the proximal edge of the soft component 26.

Each plate-type tactile component 214 may include a connecting portion that may be connected to the optical component 202. The connecting portion can include a short appendage 206 and a connecting bar 210 (eg, a torsion bar) extending laterally from the short appendage 206, eg, the connecting bar 210 is each of the short appendages 206 facing each other. It can extend laterally from the side. Each tactile component 214 may include a short appendage 206 and an elongated slot 218 forming a through hole that can be distal to the connecting bar 210.

The thickness of the connection bar 210 can be less than the thickness of the short appendage 206. The thickness of the connection bar 210 can be reduced so that at least one of extension and rotation of the connection bar 210 is possible (eg, twisted) and the movement of the optical component 202 with respect to the tactile component 214 is facilitated. Additional information regarding connection bars and adjustable lenses can be found in US Patent Application Publication No. 14/035,821, published as US Patent Application Publication No. 2014/0094909, filed September 24, 2013 ("" It can be found in "Accommodating Intraocular Lens" (agent reference number CORD.009P1), which is incorporated herein by reference in its entirety and is incorporated herein by reference. Should be considered.

Each tactile component 214 may include one or more anterior ridges 246 extending forward from the tactile component 214. An exemplary ridge 246 is described in US Patent Application Publication No. 14/035,813 (agent reference number CORD.010A) published as US Patent Application Publication No. 2015/0088254. , This in its entirety is incorporated herein by reference and should be considered as part of this specification. One or more anterior ridges 246 may at least partially traverse one or both paddles 234 of each tactile component 214. As shown in FIG. 14A, the single anterior ridge 246 can extend from one paddle 234 to the other paddle 234 of the same tactile component 214, which can be arched. In FIG. 14A, the bright, small spotted portion of the tactile component 214 is the frame 222, which portion may contain polyimide. The dark areas indicate areas where, for example, a soft component 226 containing silicone covers the frame 222. The darkest shaded area shows the ridge 246, which may include a thick area of the soft material containing the soft component 226 (eg, silicone). In this configuration, the anterior ridge 246 may at least partially surround the elongated slot 218. 14B and 14D show the cross section of the ridge projection 246. One or more anterior ridges may separate AIOL202 from the anterior capsule of the capsular bag of the human lens. FIG. 14C shows a frame 222 (dark and black region) which may contain, for example, polyimide.

Such adjustable intraocular lenses may also have other features as described elsewhere herein.
Terms In the present specification, the relative terms "base" and "tip" are defined in terms of optical components. Therefore, the base end points in the direction toward the optical component, and the tip points in the direction away from the optical component.

As used herein, the term "fixed length" or "fixed longitudinal length" means that after transplantation, the change in length when receiving the force applied by the ciliary muscle is about 5% or less (eg, about 4). % Or less, about 3% or less, about 2% or less, or about 1% or less). For example, the soft finger 5 may bend toward the center to secure the intraocular lens to the capsular bag (see FIG. 2). As used herein, the phrase "the vault angle can remain unchanged" means that after transplantation, the change is about 5% or less (eg, about 4) when subjected to force from the ciliary muscles and fibrosis. % Or less, about 3% or less, about 2% or less, or about 1% or less).

Conditional languages such as "can, can", "could", "may", or "may" are not specified unless otherwise specified. In general, a particular embodiment includes at least one of a particular feature, element, and step, but other embodiments are included, unless understood in the context of, or otherwise used. I shall tell you that there is no such thing. Therefore, such conditional languages generally have at least one of these features, elements, and steps, whether included in or implemented in any particular embodiment. At least one of the features, elements, and steps implies that it is somehow required for one or more embodiments.

As used herein, the terms "approximately," "about," and "substantially" represent quantities close to those stated that still perform the desired function or achieve the desired result. For example, in some embodiments, the terms "approximately," "about," and "substantially" can refer to quantities within the range of 5% or less of the stated amounts, as can be indicated in context.

The scope disclosed herein also includes any and all overlaps, subranges, and combinations thereof. Languages such as "maximum," "at least," "super, large," "less than," and "between" include the numbers listed. Numbers that are preceded by terms such as "about" or "approximately" include the numbers listed. For example, "about 3 mm" includes "3 mm".

Although some embodiments and examples have been described herein, those skilled in the art will appreciate that many aspects of the intraocular lens illustrated and described herein may be combined or modified differently. It should be understood that another embodiment or acceptable example can be formed. All such modifications and variations are within the scope of this disclosure herein. A wide variety of designs and methods are possible. The features, structures, or steps disclosed herein are neither essential nor essential.

Some embodiments have been described with reference to the accompanying drawings. However, it should be understood that the drawings are not on scale. Distances, angles, etc. are merely description and do not necessarily relate exactly to the actual dimensions and layout of the illustrated device. Components can be added, removed, or rearranged. Moreover, the disclosure of any particular feature, aspect, method, property, property, quality, quality, characteristic, element, etc. associated with various embodiments is in all other embodiments described herein. Can be used. Furthermore, it can be recognized that any method described herein can be performed using any device suitable for performing the listed steps.

For the purposes of this disclosure, some aspects, advantages, and novel features are described herein. It should be understood that not all such benefits can be achieved according to any particular embodiment. Thus, for example, the disclosure achieves one or a group of advantages as taught herein, but not necessarily other advantages as taught or suggested herein. Those skilled in the art will recognize that it can be embodied or implemented.

Moreover, although exemplary embodiments have been described herein, any and any having at least one of equal elements, modifications, omissions, combinations (eg, aspects across various embodiments), adaptations, and modifications. The scope of all embodiments is based on this disclosure as will be appreciated by those skilled in the art. The limitations of the claims shall be broadly construed based on the language used within the claims and shall not be limited to the examples described herein or during the proceedings. Instead, these examples are interpreted as non-exclusive. In addition, the actions of the disclosure process and method may be modified in any way, including rearranging the actions, inserting additional actions or deleting actions. The specification and examples are therefore merely explanatory and the true scope and intent shall be considered to be indicated by the claims and their equivalents in their entirety.

Claims (14)

Optical parts and
An intraocular lens comprising at least two plate-type tactile components connected to the optical component and vertically opposite to each other with the optical component in between.
Each plate-type tactile component has opposing lateral paddles.
Each of the plate-type tactile components further
Soft components and
With a rigid frame that is at least partially embedded in the soft component,
A connection portion for connecting the plate-type tactile component to the optical component is provided.
The rigid frame has at least one opening at the tip of the rigid frame, at least a portion of the opening extending beyond the tip edge of the soft component.
The cross-sectional width of the hard frame measured between the opposing lateral edges of the hard frame is greater than the cross-sectional width of the soft component measured between the opposing lateral edges of the soft component.
The hard frame extends beyond the proximal edge of the soft component.
The connecting portion includes an appendage connected to the optical component and a first torsion bar and a second torsion bar extending laterally from both lateral ends of the appendage.
The first torsion bar and the second torsion bar are intraocular lenses configured to be rotatable or stretchable. Optical parts and
An intraocular lens comprising at least two plate-type tactile components connected to the optical component and vertically opposite to each other with the optical component in between.
Each plate-type tactile component has opposing lateral paddles.
Each of the plate-type tactile components further
Soft components and
With a rigid frame that is at least partially embedded in the soft component,
A connection portion for connecting the plate-type tactile component to the optical component is provided.
The rigid frame has at least one opening at the tip of the rigid frame, at least a portion of which extends beyond the tip edge of the soft component and completely penetrates the plate-type tactile component. It is an open space to
The cross-sectional width of the hard frame measured between the opposing lateral edges of the hard frame is greater than the cross-sectional width of the soft component measured between the opposing lateral edges of the soft component.
The hard frame extends beyond the proximal edge of the soft component.
The connecting portion includes an appendage connected to the optical component and a first torsion bar and a second torsion bar extending laterally from both lateral ends of the appendage.
The first torsion bar and the second torsion bar are intraocular lenses configured to be rotatable or stretchable. The intraocular lens according to claim 1 or 2 , wherein the soft component and the optical component contain the same material. The intraocular lens according to any one of claims 1 to 3 , wherein the soft component contains silicone or acrylic. The intraocular lens according to any one of claims 1 to 4 , wherein the hard frame extends at least in both the longitudinal direction and the lateral direction within the soft component. The intraocular lens according to any one of claims 1 to 5 , wherein the rigid frame includes a closed loop surrounding the opening at a tip end portion of the rigid frame. The intraocular lens according to any one of claims 1 to 6 , wherein the intraocular lens further includes an elongated slot. The intraocular lens according to any one of claims 1 to 7 , further comprising at least one anterior projection extending forward from each plate-type tactile component. The aspect according to any one of claims 1 to 8 , wherein the transverse width measured between the outer lateral edges of the opposing lateral paddles in each plate-type tactile component is wider than the transverse width of the optical component. Intraocular lens. The intraocular lens according to any one of claims 1 to 9 , wherein each plate-type tactile component is hard in the vertical direction and soft in the horizontal direction. The intraocular lens according to any one of claims 1 to 10 , wherein each plate-type tactile component is laterally soft enough to be inserted into the eye. The intraocular lens according to any one of claims 1 to 11 , wherein the lateral paddle at least partially surrounds the optical component. The intraocular lens according to claim 7 , wherein each plate-type tactile component includes the elongated slot. Claimed that the intraocular lens is planar and when the intraocular lens is implanted in the eye, the optical component can be arched posteriorly with respect to the tip of the plate-type tactile component. Item 2. The intraocular lens according to any one of Items 1 to 13 .

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