JP6887832B2 - Topical skin or cosmetics - Google Patents

Description

The present invention relates to an external preparation for skin or a cosmetic.

In recent years, there has been a strong demand for skin external preparations and cosmetics to block ultraviolet rays in the sun's rays and to impart the effect of protecting the skin from the adverse effects of ultraviolet rays, and metal oxides such as zinc oxide and titanium oxide have been strongly required. Skin external preparations and cosmetics having a high UV protection effect have been developed by containing powders and organic UV absorbers. Further, in skin external preparations and cosmetics, excellent uniformity of the cosmetic film is one of the important qualities in order to exert a high ultraviolet protection effect, and various studies have been conducted.
For example, as a technique for improving the uniformity of a decorative film, a technique using an organic ultraviolet absorber, a water-soluble thickener, a specific hydrophilic nonionic surfactant, and a lipophilic surfactant (see Patent Document 1) and the like. It has been known.

On the other hand, humus soil is terrestrial plants, plants such as large and microalgae (in a broad sense), seafood and other inorganic substances deposited on the bottom of the sea, swamps, ponds and lakes, uplifted on the ground surface, and forests. Plants (in a broad sense) and sediments containing them, such as those deposited on the surface of the sea, have been decomposed and organicized by anaerobic microorganisms over a long period of time. This humus extract is known to contain fatty acids, organic acids, amino acids, proteins, minerals, etc., in addition to constituents peculiar to humic acid such as fulvic acid and humic acid. And their inclusion in cosmetics has been studied (see Patent Document 2). In addition, humic acid extract or its component humic acid (fulvic acid, humic acid, etc.) has been found to have type I allergy-suppressing action, antibacterial / bactericidal action, virus inactivation, etc., and is effective in external skin preparations and cosmetics. It has been studied to be used as an ingredient and has been attracting attention in recent years (see Patent Documents 2 and 3).

Japanese Unexamined Patent Publication No. 2008-162930 Japanese Unexamined Patent Publication No. 2000-136140 Japanese Unexamined Patent Publication No. 2006-232785

However, since humic acid, which is a constituent component peculiar to humus extract, has a large number of polar groups in the molecule, it is strongly sticky when contained in a pharmaceutical product, lacks spreadability, and impairs the uniformity of the cosmetic film. There is a problem that it is removed, which may cause a decrease in the ultraviolet protection effect of external preparations for skin and cosmetics. Further, in the technique using a specific hydrophilic surfactant, lipophilic surfactant, etc. (see Patent Document 1), when the content of the surfactant is increased in order to improve the uniformity of the cosmetic film, the surfactant is used. The origin was sticky, and a satisfactory and smooth spread was not obtained.
Therefore, it has been desired to develop an external preparation for skin and a cosmetic which spreads smoothly and has an excellent ultraviolet protection effect while containing a humus extract.

As a result of sincere examination, the inventor has made it smooth even if it contains a humus extract by containing a spherical powder with an average particle size of 5 to 30 μm, which has excellent spreadability and uniform adhesion. It has been found that an external preparation for skin or a cosmetic having an excellent UV protection effect can be obtained, and the present invention has been completed.

That is, the present invention describes the following components (A) to (C);
(A) Corrosive soil extract (B) Organic UV absorber and / or metal oxide powder (C) Skin external preparation or cosmetic containing spherical powder with an average particle size of 5 to 30 μm.

The component (A) humus extract is an aqueous solvent extract for external use on the skin or cosmetics.

A skin external preparation or cosmetic containing 100 mg / L or more of humic acid when the humus extract of the component (A) is dissolved or suspended in water so that the extract concentration is 0.5% by mass. Fee,

For external use on the skin, the component (A) humus extract contains 0.1 to 100 mg / L of fulvic acid when dissolved or suspended in water so that the extract concentration is 0.5% by mass. Agent or cosmetic,

A skin external preparation or cosmetic having an average particle size of the component (C) of 5 to 15 μm.

A skin external preparation or cosmetic in which the component (C) is one or more selected from silicone-based resin powder, acrylic-based resin powder, and silicic anhydride powder.

A skin external preparation or cosmetic having a mass ratio of the component (A) to the component (C) of (A) :( C) = 1: 1 to 1: 100,000.

It provides a skin external preparation or cosmetic in which the skin external preparation or cosmetic is an emulsion.

The present invention relates to an external preparation for skin or a cosmetic, and more specifically, it has a smooth spreading and spreading, an excellent uniformity of a cosmetic film, and a high ultraviolet protection effect.

Details of the present invention will be described below. In addition, in this specification, "~" means the range including the numerical values before and after it.

In the present invention, the method for measuring the average particle size of the metal oxide powder of the component (B) and the spherical powder of the component (C) is to use a scanning electron microscope to measure 10 particles in an arbitrary field of view. Calculated from the result of measuring the diameter.

The component (A) used in the present invention is a humus extract. The humus soil of the humus soil extract used in the present invention is not particularly limited, and any humus soil can be used regardless of the place of origin or condition. Specifically, as this humus soil, for example, those originating from forests, rivers, lakes, marshes, oceans, etc. can be used, and this humus soil is the above-ground plants that inhabited there, large-scale, and so on. Plants such as microalgae (in a broad sense) and sediments containing them are decomposed, synthesized, and organicized by anaerobic microorganisms. Of these, humus soil originating from sediments formed in the ocean, more preferably humus soil derived from the Japanese archipelago in which sediments formed in the ocean are uplifted, and humus soil derived from Kyushu is more preferable. .. The degree of humus of this humus soil is not particularly limited, and those in which humus progresses and contains high molecular weight organic compounds such as fulvic acid and humic acid are preferable.

The humus extract used in the present invention is obtained by bringing the humus soil into contact with a solvent by an extraction means to extract an effective component and recover it. Further, it is preferable to use a filtration means for removing unnecessary substances and sterilizing bacteria. The obtained humus soil extract can be diluted, concentrated or dried, if necessary, and may be separated or purified to remove impurities. The form of the humus extract is not particularly limited, and examples thereof include a solid state, a semi-solid state, and a liquid state. Specific examples include states such as solutions, suspensions, concentrates, emulsions, slurries, powders, granules and solids. Further, the humus soil extract refers to a composition or a component peculiar to corroded soil obtained from humus soil by an extraction operation, unless otherwise specified. The humus extract can be humic acid, humic acid or fulvic acid.

As an example of a method for producing a suitable humus extract, an extraction solvent is added to the humus, the mixture is stirred and then the active ingredient is separated to obtain the humus extract.

The extraction means is not particularly limited, and examples thereof include solid-liquid extraction, liquid-liquid extraction, immersion, brewing, leaching, reflux extraction, supercritical fluid extraction, ultrasonic extraction, microwave extraction, and mixed stirring. These may be combined appropriately. The separation means is not particularly limited, and examples thereof include filtration separation means and centrifugal separation means. These may be used alone or in combination. Examples of the filtration separation means include natural filtration, reduced pressure filtration and pressurized filtration. At this time, a filter medium such as a cellulose filter, a glass fiber filter, or a membrane filter is used, and if necessary, a filtration aid such as Celite, gravel, or activated carbon is used. The pore size is not particularly limited, and for example, 0.1 to 1 μm is preferable. These may be combined appropriately. The humus extract is preferably filtered using a sterilization filter because the humus is not heat-denatured and insoluble substances and the like are removed.
In addition, there is no particular limitation on the presence or absence and method of drying and pretreating the humus soil prior to extraction.

The extraction solvent is not particularly limited, and either an aqueous solvent or an oil solvent may be used. Aqueous solvents include water (hot spring water, water containing minerals such as deep ocean water, purified water, etc.); linear, branched or cyclic alcohols; ketones such as acetone and methyl ethyl ketone; methyl acetate, ethyl acetate. Esters such as; chain and cyclic ethers such as tetrahydrofuran and diethyl ether; polyethers such as polyethylene glycol and the like; examples of the oily solvent include hydrocarbons such as squalane, hexane, cyclohexane and petroleum ether; toluene. Aromatic hydrocarbons such as; halogenated hydrocarbons such as dichloromethane, chloroform, dichloroethane and the like. These may be used alone or as a mixed solvent of two or more kinds.

According to the study of the present inventor, among the components contained in the humus extract, one of the components having a high desired effect is considered to be fulvic acid. Therefore, fulvic acid is used as the extraction solvent for the humus extract. It is preferably soluble. Specifically, an aqueous solvent, that is, a solvent containing water is preferable, and water or a mixed solution of water and alcohols is more preferable.

Here, the alcohols may be either monohydric or polyhydric alcohols, examples of the monohydric alcohols include methanol, ethanol and propanol, and examples of the polyhydric alcohols include ethylene glycol and the like. Examples thereof include propylene glycol, 1,3-butylene glycol, 1,2-pentanediol, glycerin and dipropylene glycol. Among the alcohols, for example, lower alcohols having 1 to 5 carbon atoms such as ethanol and 1,3-butylene glycol are preferable, of which lower monohydric alcohols are preferable, and ethanol is more preferable.

When water or a mixed solution of water and alcohols is taken as 100% by volume, the content of alcohols is 0 to 90% by volume, preferably 0 to 70% by volume, and more preferably 0 to 50% by volume. More preferably, it is 0 to 20% by volume.

The amount of the solvent used is not particularly limited, and is preferably 100 to 1000 L, preferably 200 to 600 L, for 100 kg of humus soil (dry state) in terms of extraction efficiency and work efficiency of the humus soil component. It is more preferable to do so.

The extraction period is not particularly limited, and is preferably 1 day to 3 years, more preferably 10 days to 1.5 years. The mixing and stirring of the humus soil and the extraction solvent at this time is not particularly limited, and may be performed, for example, for about 0.5 to 48 hours. As a result, the humus soil and the extraction solvent come into contact with each other, and the active ingredient can be easily extracted. Further, the mixing and stirring may be performed continuously or discontinuously. For example, it is preferable in terms of extraction efficiency that the mixture is mixed and stirred for a certain period of time, mixed and stirred for a certain period of time and then left to stand, or left to stand for aging. It is preferable to leave the humus soil after mixing and stirring because it is advantageous for separation. For example, during the extraction period (for example, 1 to 3 years), the mixture is stirred continuously or discontinuously; after the mixture is stirred for 1 to 7 days, it is left to stand for 1 to 60 days (preferably 20 to 40 days); After mixing and stirring for 1 to 20 days (preferably 3 to 9 days), the mixture may be left for 1 to 3 years (preferably 6 to 2 years).

The extraction temperature is not particularly limited, and is preferably low temperature to high temperature (for example, about 0 to 100 ° C.), more preferably low temperature (for example, about 0 to 9 ° C.) to normal temperature (for example, about 10 to 40 ° C.). Is suitable because it does not heat-denature the humus.

Examples of the drying include sun drying, natural drying, air drying, heat drying, freeze drying and the like, and it is preferable if the humus soil is not heat-denatured. At this time, it is desirable that the humus soil is dried to such an extent that it can be finely pulverized, and pulverization improves the extraction efficiency of the humus soil, which is preferable.

The humus extract contains constituent substances (humic acid, etc.) peculiar to humic soil such as fulvic acid and humic acid, and fatty acids, organic acids, amino acids, proteins, minerals and the like.

The humic acid extract contains at least 0.1 mg / L or more, preferably 10 mg / L or more of humic acid when dissolved or suspended in water so that the extract concentration becomes 0.5% by mass. It is preferably contained in an amount of 100 mg / L or more, more preferably 100 to 1000 mg / L, further preferably 200 to 700 mg / L, still more preferably 350 to 650 mg / L. Here, humic acid (humic acid) refers to, for example, a polymer substance produced by decomposing and condensing plant components and the like in soil. Here, humic acid can be quantified by the test method for humic acid of the mineral spring test method (sanitary test method / commentary 2002, Pharmaceutical Society of Japan). The details of the test method are as follows.

Accurately take sample VmL (containing about 20 mg or more as humus), suction filter using a 0.45 μm membrane filter (previously dried with a desiccator (silica gel) and weighed), and wash with a small amount of water. After that, combine the filtrate and washing solution, add 10 mL of HCl, stir well, and leave it for a whole day and night. This is filtered with a membrane filter. For filtration, the supernatant is first gently suction-filtered, and finally a precipitate is added. After filtering, wash the precipitate thoroughly with water. The filtrate is usually somewhat colored. When there is a lot of fulvic acid, coloring is remarkable. After filtration, peel off the filter part, wrap it in paraffin paper, and dry it in a desiccator (silica gel) until it reaches a constant weight (leave it for a whole day and night). The amount of humus is calculated by subtracting the weight of the membrane filter, and the content in the sample is calculated. Since the humus contains ash, transfer the methanol filter to a crucible, add a small amount of methyl alcohol to burn it, and then incinerate it to obtain ash, which is subtracted from the previous weight.

Huminic acid (humus) (mg / L) = ((AB) -C) / D × 100

A: Weight of filter part (mg)
B: Weight of membrane filter (mg)
C: Weight of ash (mg)
D: Sample collection amount (ml)

According to the study by the present inventor, the desired effect was sufficiently observed in the humus extract obtained by using water as a solvent. Therefore, one of the components having a high desired effect is fulvic acid among the humic acids. It is considered. Therefore, it is preferable that the humus extract used as an active ingredient contains a large amount of fulvic acid, and specifically, when it is dissolved or suspended in water so that the solid content concentration becomes 0.5% by mass. Fulvic acid is preferably contained in an amount of 0.1 to 100 mg / L, more preferably 1 to 50 mg / L, and even more preferably 5 to 50 mg / L. Here, fulvic acid refers to an amorphous high molecular weight organic acid that is not precipitated by an acid among humic substances that are the final products of plants and the like being decomposed by microorganisms. Fulvic acid may have a chelating action that adsorbs and releases heavy metals and the like.

In the humus extract, humic acid is preferably 0.2 mg / L or more, more preferably 2 mg or more, and further, when dissolved or suspended in water so that the extract concentration becomes 0.5% by mass. It is preferably contained in an amount of 3 mg / L or more, more preferably 4 mg / L or more. In any case, the amount of humic acid in the humus extract can be preferably 30 mg / L or less, 20 mg or less, or 1.6 mg / L or less. Humic acid refers to humic acid that precipitates in the acidic region and is soluble in the alkaline region. Although the detailed chemical structure is unknown, it is a condensate of a polyhydric phenolic aromatic compound and a nitrogen-containing compound, and is said to have a phenolic hydroxyl group and a carboxyl group.

The mixing ratio of humic acid: fulvic acid is not particularly limited, and is preferably 1:10 to 10: 1. A method for quantifying humic acid and fulvic acid is described in "Soil Science and Plant Nutrition, Vol. 38, pp. 23-30 (Kuwatsuka S et al. 1992); Soil Science and
Plant Nutrition, Vol. 40, pp. 601-608 (Watanabe A. et al. 1994); Humic Substances Research, Vol. 1, pp. 18-28 (Watanabe A. et al. 2004) ”. When the quantified value differs depending on the measuring method, it is preferable to adopt the measuring method having a higher quantified value of fulvic acid.

The pH of the humus extract is preferably in the acidic range, preferably pH 1 to 6, more preferably pH 2 to 5, from the viewpoint of pharmacological activity and stability. At this time, an aqueous solution having an extract concentration of 0.1 to 1% by mass may be prepared and adjusted appropriately with a pH adjuster at 20 ° C. The pH adjuster is not particularly limited as long as it is usually used, and for example, inorganic acids such as hydrochloric acid, sulfuric acid, nitrate, carbonic acid, and phosphoric acid; citric acid, acetic acid, lactic acid, succinic acid, glycolic acid, and ascorbin. Organic acids such as acids, malic acid, fumaric acid, tartaric acid, urea, ε-aminocaproic acid, pyrrolidonecarboxylic acid; betaines such as glycine betaine and lysine betaine; metallic water such as sodium hydroxide, potassium hydroxide and calcium hydroxide. Inorganic alkalis such as oxides (alkali metal hydroxides and alkaline earth metal hydroxides, etc.); Organic amines such as guanidine, 2-amino-2-methylpropane; ammonia, monoethanolamine, diethanolamine, triethanol Alkanoylamines such as amines, isopropanolamines and diisopropanolamines; basic amino acids such as arginine and lysine, and combinations thereof.

The content of the component (A) humus extract used in the present invention is not particularly limited, but 0.00001 to 1% by mass (hereinafter, mass% is simply mass%) as the extract content in the total amount of the external preparation for skin or cosmetics. , "%"), And more preferably 0.0001 to 0.1% in terms of utility and the like.

The component (B) used in the present invention is not particularly limited as long as it is an organic ultraviolet absorber and / or a metal oxide powder, and any component (B) that can be used as an external preparation for skin or cosmetics is used. it can.

Examples of the organic ultraviolet absorber include benzophenone type, PABA type, cinnamic acid type, salicylic acid type, silicone type and the like, and one type or a combination of two or more of these can be used. Specifically, 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoic acid hexyl ester, oxybenzone, 4-tert-4'-methoxydibenzoylmethane, 2,4-bis- [{4- (2). -Ethylhexyloxy-2-hydroxy} -phenyl] -6- (4-methoxyphenyl) -1,3,5-triazine, 2-hydroxy-4-methoxybenzophenone, -2-ethylhexyl salicylate, ethyl paradihydroxypropyl benzoate , 2-Ethylhexyl dimethoxybenzidioxoimidazolidine propionate, 2,2'-methylenebis [6- (2H-benzotriazol-2yl) -4- (1,1,3,3-tetramethylbutyl) phenol], (1,3,5) -Triazine-2,4-bis [{4- (2-ethylhexyloxy) -2-hydroxy} -phenyl] -6- (4-methoxyphenyl) -1,3,5- Examples thereof include triazine, dimethicodiethylbenzalmalonate, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid and its sodium salt, polysilicone-15, etc., and these may be used alone or in combination of two or more. it can.

Examples of the metal oxide powder include zinc oxide, titanium oxide, cerium oxide, aluminum oxide, and the like, and if they are generally used for skin external preparations or cosmetics, they are spherical, plate-shaped, or needle-shaped. It is not particularly limited by the shape such as shape, the particle size such as fumes, fine particles, pigment grade, etc., and the particle structure such as porous and non-porous, and these can be used alone or in combination of two or more. The average particle size of the metal oxide powder is preferably 15 to 1000 nm from the viewpoint of obtaining a high ultraviolet protection effect, and more preferably 25 to 850 nm because these effects are particularly remarkable. These powders are subjected to known surface treatment methods such as silicon dioxide treatment, alumina treatment, aluminum hydroxide treatment, fluorine compound treatment, silicone treatment, silicone resin treatment, pendant treatment, silane coupling agent treatment, and titanium coupling. Surface treatment may be performed by a method such as agent treatment, silane treatment, oil agent treatment, N-acylated lysine treatment, polyacrylic acid treatment, metal soap treatment, acrylic resin treatment, and metal oxide powder treatment.
Commercially available metal oxide powders include, for example, FINEX-50 (manufactured by Sakai Chemical Industry Co., Ltd.), ZnO-350 (manufactured by Sumitomo Osaka Cement Co., Ltd.), zinc oxide FZO-50 (manufactured by Ishihara Sangyo Co., Ltd.), and fine particle zinc oxide MZ. -500 (manufactured by Teika), TIPAQUE CR-50 (manufactured by Ishihara Sangyo), TIPAQUE A-100 (manufactured by Ishihara), TITANIX JR-800 (manufactured by Teika), MICRO TITANIUM DIOXIDE MT-500SA (manufactured by Teika) ), Etc., and these can be used alone or in combination of two or more.

The content of the component (B) organic ultraviolet absorber and / or metal oxide powder used in the present invention is not particularly limited, but is 0.5 to 40% with respect to the total amount of the external preparation for skin or cosmetics. If there is, it is preferable in that a high ultraviolet protection effect can be obtained, and if it is 1.5 to 30%, those effects are particularly remarkable, which is more preferable.

The spherical powder having an average particle diameter of 5 to 30 μm of the component (C) of the present invention may be porous, non-porous, hollow, multi-layered or the like as long as it is a spherical powder usually used for external preparations for skin or cosmetics. The particle structure and the like are not particularly limited, and examples thereof include organic powder and inorganic powder. Specifically, organopolysiloxane elastomer, methylsiloxane reticulated polymer, crosslinked silicone / reticulated silicone block copolymer, alkylpolyacrylate, polyethylene, polystyrene, nylon, urethane, wool, silk, crystalline cellulose, N- Examples thereof include organic powders such as acylidine, inorganic powders such as silicic anhydride and calcium carbonate, and one or more of these can be used. Among these spherical powders, silicone-based resin powders such as organopolysiloxane elastomers, methylsiloxane reticulated polymers, crosslinked silicone / reticulated silicone block copolymers, and acrylic resin powders such as alkyl polyacrylates. In the case of non-positively charged spherical powder such as silicic anhydride powder, there is little interaction with the fuminaceous material, and the excellent spreadability and uniform adhesion inherent in the spherical powder are more excellent. preferable. Among them, organopolysiloxane elastomers, methylsiloxane reticulated polymers, crosslinked silicone / reticulated silicone block copolymers, alkyl polyacrylates, and spherical powders of silicic acid anhydride are particularly preferable, and one or two of these are particularly preferable. The above can be used in combination. Commercially available products include Trefil E505, E506, and E701 (all manufactured by Toray Dow Corning Silicone), which are organopolysiloxane elastomers, and Tospearl 2000B * (manufactured by Toshiba Silicone), which is a methylsiloxane reticulated polymer. Matsumoto Microsphere M-101, 305, which is an alkyl polyacrylate, such as SP-100, 101, 102, 105, 300 (all manufactured by Shin-Etsu Chemical Industry Co., Ltd.), which are cross-linked silicone / reticulated silicone block copolymers. (All manufactured by Matsumoto Yushi Pharmaceutical Co., Ltd.), Ganzpearl GM-2800 (manufactured by Aika Kogyo Co., Ltd.), etc. (Manufactured by Kaseisha) and the like.

Further, the spherical powder having an average particle diameter of 5 to 30 μm of the component (C) is treated with known surface treatment methods such as silicic anhydride treatment, alumina treatment, aluminum hydroxide treatment, fluorine compound treatment, silicone treatment, and silicone resin treatment. , Pendant treatment, silane coupling agent treatment, titanium coupling agent treatment, silane treatment, oil agent treatment, N-acylated lysine treatment, polyacrylic acid treatment, metal soap treatment, acrylic resin treatment, metal oxide treatment, etc. The surface may be treated.

The average particle size of the component (C) is 5 to 30 μm, more preferably 5 to 15 μm. If the average particle size is less than 5 μm, satisfactory ductility and smooth spreading and spreading cannot be obtained, and if the average particle size exceeds 30 μm, satisfactory uniform adhesion of the cosmetic film cannot be obtained, and ultraviolet rays are not obtained. It may cause a decrease in the protective effect.

The content of the spherical powder having an average particle size of 5 to 30 μm of the component (C) used in the present invention is not particularly limited, but is preferably 0.0001 to 50% with respect to the total amount of the external preparation for skin or cosmetics. , 0.001 to 40%, more preferably 0.1 to 20%. This range is more preferable in terms of smooth spread and spread and excellent UV protection effect.

In the present invention, although not particularly limited, the content mass ratio of the component (A) to the component (C) is preferably (A) :( C) = 1: 1 to 1: 100,000, preferably 1: 10 to 1. : 10000 is more preferable. This range is more preferable in terms of smooth spread and spread and excellent UV protection effect.

In addition to the above-mentioned components (A) to (C), the skin external preparation or cosmetic of the present invention includes components usually used for skin external preparations or cosmetics, oily components, inorganic pigments, organic pigments, pigments and the like. Aqueous components such as powders and their silicone-treated products and fluorine compound-treated products, surfactants, fibers, polyhydric alcohols, water-soluble polymers, water-soluble film-forming resins, moisturizers, sugars, antioxidants, erasing agents. Foaming agents, beauty ingredients, preservatives, fragrances and the like can be contained within a range that does not interfere with the effects of the present invention.

As the oily component, any oil usually used for external skin preparations or cosmetics can be used without particular limitation, and the origin of animal oils, vegetable oils, synthetic oils, etc., semi-solid oils, liquid oils, volatile oils, etc. Regardless of the properties, hydrocarbons, oils and fats, ester oils, fatty acids, higher alcohols, fluorine-based oils and the like can be used. Specifically, liquid paraffin, squalane, vaseline, hydrocarbons of polyisobutylene, fats and oils such as olive oil, mink oil, macadamia nut oil, cetyl isooctanoate, isopropyl myristate, isopropyl palmitate, octyldodecyl myristate, dioctanoic acid. Neopentyl glycol, tri (caprylic acid / capric acid) glyceryl, jojoba oil, glyceryl tri2-ethylhexanoate, esters such as diisostearyl malate, fatty acids such as isostearic acid and oleic acid, oleyl alcohol, isostearyl Examples thereof include higher alcohols such as alcohol, fluorine-based oils such as perfluorodecane, perfluorooctane, and perfluoropolyether, and oil-soluble beauty ingredients.

As the powder component, if it is a powder other than the components (B) and (C) generally used as a powder for external use on the skin or cosmetics, it has a plate-like shape, a needle-like shape, a smoke-like shape, etc. It is not particularly limited by the particle size such as fine particles and pigment grade, and the particle structure such as porous and non-porous, and is not particularly limited. Inorganic powders, glittering powders, organic powders, pigment powders, metal powders, etc. Classes, composite powders and the like. Specifically, colored inorganic pigments such as iron oxide, carbon black, chromium oxide, chromium hydroxide, dark blue, and ultramarine, talc, white mica, gold mica, red mica, black mica, synthetic mica, and silk mica (seri). Site), synthetic sericite, barium sulfate, kaolin, silicon carbide, bentonite, smectite, silica soil, aluminum silicate, aluminum magnesium metasilicate, calcium silicate, barium silicate, magnesium silicate, magnesium carbonate, hydroxyapatite, White constitution powder such as boron nitride, titanium oxide coated mica, titanium oxide coated bismuth oxychloride, titanium oxide mica, dark blue treated mica titanium, carmine treated mica titanium, bismuth oxychloride, fish scale foil, polyethylene terephthalate / aluminum / epoxy laminate Glitter powder such as powder, polyethylene terephthalate / polyolefin laminated film powder, polyethylene terephthalate / polymethylmethacrylate laminated film powder, organic low molecular weight powder such as zinc stearate, N-acylidine, silk powder, cellulose powder, dextrin powder. Natural organic powders such as red 201, red 202, red 205, red 226, red 228, orange 203, orange 204, blue 404, yellow 401, etc., red 3, red Organic pigment powders such as zirconium, barium or aluminum lake such as 104, red 106, orange 205, yellow 4, yellow 5, green 3 and blue 1, or aluminum powder, gold powder, silver powder and the like. Composite powders such as metal powder, fine particle titanium oxide coated mica titanium, fine particle zinc oxide coated mica titanium, barium sulfate coated mica titanium, titanium oxide-containing silicon dioxide, zinc oxide-containing silicon dioxide, nylon, polyester, rayon, cellulose, etc. Examples include fibers. These may be surface-treated with a fluorine compound, silicone oil, powder, oil agent, gelling agent, surfactant or the like. As these powders, one kind or two or more kinds can be used, and a composite one may be used.

As the surfactant, any of the surfactants generally used for external skin or cosmetics can be used, and nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants can be used. Examples include surfactants.
The aqueous component may be any component soluble in water, and in addition to water, for example, propylene glycol, 1,3-butylene glycol, dipropylene glycol, glycerin, diglycerin, polyglycerin, aloe vera, witch. Examples thereof include plant extracts such as hazel, hamamelis, cucumber, lemon, lavender, and rose water.
Examples of antioxidants include tocopherol, ascorbic acid, etc., cosmetic ingredients include, for example, vitamins, anti-inflammatory agents, crude drugs, etc., and preservatives include, for example, paraoxybenzoic acid ester, phenoxyethanol, 1,2-pentadiol and the like. ..

The external preparation for skin or cosmetic of the present invention can be produced according to a conventional method. For example, a surfactant or other oil agent is added to the components (A) and (B), and the mixture is heated to 90 ° C. and uniformly mixed. It can be obtained by adding it to the component (A) previously mixed with another aqueous component or the like.

The properties of the external preparation for skin or cosmetics of the present invention are not particularly limited, and may be any of liquid, gel, cream, semi-solid, solid, stick, powder and the like.

Examples of the skin external preparation or cosmetic of the present invention include skin external preparations such as pharmaceuticals and cosmetics. For example, external solid preparations, external liquid preparations, sprays, ointments, creams, gels, etc. Patches, milky lotions, lotions, pack cosmetics, wash pigments, massage cosmetics, hair cosmetics, sunscreens, body powders, body creams and other body cosmetics, daytime beauty liquids, etc. Beauty liquid, eye cream and other eye care cosmetics, lip essence, lip cream and other lip care cosmetics, foundation, foundation, concealer, white powder, eye shadow, cheek red, lipstick, mascara, eyebrow and other makeup preparations, etc. Can be mentioned. On the other hand, examples of the dosage form of the external preparation for skin or cosmetics of the present invention include water-based, O / W emulsifying, W / O emulsifying, oil-based, and powder-based, and in particular, organic ultraviolet absorption of the component (B). The O / W emulsification system and the W / O emulsification system are preferably used in that the agent and / or the metal oxide powder can be contained in a high content and a high ultraviolet protection effect can be obtained.

The present invention will be described in detail below with reference to production examples and examples. It should be noted that these do not limit the present invention in any way.
[Production example 1: Production of humus soil extract]
Corroded soil collected from the ground (soil near the coast of the Kyushu region) was dried and then finely pulverized. 5 kg of this pulverized product and 20 liters of purified water were mixed and stirred for 2 hours, further stirred at room temperature (about 10 to 30 ° C.) for 7 days, and allowed to stand for 20 days. After standing, it was filtered using a membrane filter (pore size 0.45 μm) to obtain an aqueous solution of humus extract (stock solution). The pH (20 ° C.) at this time was 3.0. The dry extract content (extract concentration) was 0.4%. The total amount of humic acid contained in this stock solution is 350 mg / L (438 mg / L when converted to an aqueous solution of 5 g of dry extract / 1 L of water), and the contents of humic acid and fulvic acid are 4 mg / L and 4 mg / L, respectively. It was 6.7 mg / L (5 mg / L and 8.4 mg / L, respectively, when converted to an aqueous solution of 5 g of dry extract / 1 L of water). In the following examples, the dried extract was used as it was.

For methods of quantifying humic acid and fulvic acid, see References Soil Science and Plant Nutrition, Vol. 38, pp. 23-30 (Kuwatsuka S et al. 1992); Soil Science and Plant Nutrition, Vol. 40, pp. 601-608 ( Watanabe A. et al. 1994); Humic Substances Reseacrh, Vol. 1, pp. 18-28 (Watanabe A. et al. 2004).

Examples 1 to 8 and Comparative Examples 1 to 4: W / O emulsifying liquid foundation The W / O emulsifying liquid foundation having the formulation shown in Table 1 below was prepared. Smooth expansion and spread, b. The UV protection effect was evaluated by the following evaluation method. The results are also shown in Table 1.

(Evaluation method)
For the following items (a), each sample was tested for use by 20 specialized panels. Each panel member evaluated and scored on a 7-point scale according to the following evaluation criteria 1, calculated the average value from the total score of all the panels, and judged according to the following criteria 1.
Regarding the items in (b) below, each sample was applied to a polymethylmethacrylate plate at a thickness of 50 μm, dried at room temperature for 24 hours, and then the SPF value was measured three times with an SPF analyzer UV-2000S (manufactured by Labsphere). , Judgment was made according to the following criteria 2.
(Evaluation item)
I. Smooth expansion and spread b. UV protection effect

<Evaluation Criteria 1>
(Score): (Evaluation)
6: Very good 5: Good 4: Somewhat good 3: Normal 2: Somewhat bad 1: Bad 0: Very bad <Criteria 1>
(Judgment): (Average score)
◎: Over 5 points
◯: Over 3.5 points and 5 points or less
△: More than 1 point and less than 3.5 points
×: 1 point or less
<Criteria 2>
(Judgment): (Average value of SPF measurement result (N = 3))
◎: More than 25 ○: More than 20 and less than 25 ×: More than 20

(Production method)
A: Ingredients (1) to (11) are uniformly mixed and dispersed by a roll mill.
B: Add components (12) to (22) to A and mix uniformly.
The container is filled with D: C to be emulsified by adding the components (23) to (29) to C: B.

As is clear from the results in Table 1, the W / O emulsified liquid foundations of Examples 1 to 8 of the present invention have a smooth spread and spread and an excellent UV protection effect as compared with Comparative Examples 1 to 4. It was.
On the other hand, in Comparative Example 1 in which the component (C) was not contained, the stickiness was strong, the smooth spread and spread was lacking, and the cosmetic film was not uniform, so that the UV protection effect was also lacking, and a satisfactory one could not be obtained. .. Further, in Comparative Example 2 in which the content of the dispersant was increased instead of containing the component (C) in order to improve the dispersibility of the powder or the like, stickiness derived from the dispersant appeared and the powder spread smoothly. Since it did not spread and the cosmetic film was not uniform, a satisfactory UV protection effect could not be obtained. In Comparative Example 3 in which a spherical powder having an average particle size of 45 μm was used instead of the component (C), although it was excellent in spreading and spreading, it was prone to unevenness due to the large average particle size, and the uniformity of the decorative film was inferior. It lacked the UV protection effect, and I could not obtain a satisfactory one. In Comparative Example 4 in which a powder having an elliptical bowl shape was used instead of the component (C), a satisfactory smooth spread and spread could not be obtained due to lack of ductility, and the cosmetic film was not uniform, so that ultraviolet rays were emitted. The protective effect was not sufficient, and I was not satisfied with it.

Examples 9 to 16 and Comparative Examples 5 to 8: O / W emulsifying sunscreens The O / W emulsifying sunscreens having the formulations shown in Table 2 below were prepared. Smooth expansion and spread, b. The UV protection effect was evaluated by the following evaluation method. The results are also shown in Table 2.

(Evaluation method)
For the following items (a), each sample was tested for use by 20 specialized panels. Each panel member evaluated the evaluation criteria 1 on a 7-point scale and gave a score, and the average value was calculated from the total score of all the panels, and the evaluation was made according to the above criteria 1.
Regarding the items in (b) below, each sample was applied to a polymethylmethacrylate plate at a thickness of 50 μm, dried at room temperature for 24 hours, and then the SPF value was measured three times with an SPF analyzer UV-2000S (manufactured by Labsphere). , Judgment was made according to the following criteria 3.
(Evaluation item)
I. Smooth expansion and spread b. UV protection effect

<Criteria 3>
(Judgment): (Average value of SPF measurement result (N = 3))
◎: More than 55 ○: More than 50 and less than 55 ×: More than 50

(Production method)
A: Ingredients (1) to (19) are uniformly mixed and dispersed.
B: Ingredients (20) to (27) are uniformly mixed and dissolved at 70 ° C.
C: Add B to A and emulsify D: C is filled in a container.

As is clear from the results in Table 2, the O / W emulsified sunscreens of Examples 9 to 16 of the present invention have a smooth spread and spread and an excellent UV protection effect as compared with Comparative Examples 5 to 8. It was.
On the other hand, in Comparative Example 5 in which the component (C) was not contained, the stickiness was strong, the smooth spread and spread was lacking, and the cosmetic film was not uniform, so that the UV protection effect was also lacking, and a satisfactory one could not be obtained. .. Further, in Comparative Example 6 in which the content of the dispersant was increased instead of containing the component (C) in order to improve the dispersibility of the powder or the like, stickiness derived from the dispersant appeared and the powder spread smoothly. Since it did not spread and the cosmetic film was not uniform, a satisfactory UV protection effect could not be obtained. In Comparative Example 7 in which a spherical powder having an average particle size of 45 μm was used instead of the component (C), although it was excellent in spreading and spreading, it was prone to unevenness due to the large particle size, and the uniformity of the decorative film was inferior. It lacked a protective effect, and I was not satisfied with it. In Comparative Example 8 in which a powder having an elliptical bowl shape was used instead of the component (C), a satisfactory smooth spread and spread could not be obtained due to lack of ductility, and the cosmetic film was not uniform, so that ultraviolet rays were emitted. The protective effect was not sufficient, and I was not satisfied with it.

Example 17: O / W emulsifying daytime beauty essence (ingredient) (%)
(1) Remaining amount of purified water (2) Carboxyvinyl polymer * 22 0.2
(3) Glycerin 8
(4) Polyoxyethylene glycerin (26EO) 5
(5) Polyoxypropylene methylglucoside 3
(6) Dipropylene glycol 8
(7) Methylparaben 0.3
(8) Hydrolyzed hyaluronic acid 0.01
(9) Hydrolyzed collagen 0.01
(10) (Ascorbyl / Tocopheryl) K 0.01
(11) Humus soil extract * 16 10
(12) Sodium hydroxide 1.5
(13) Red 227 0.0005
(14) Yellow 4 0.0005
(15) Cross-linked silicone / reticulated silicone block copolymer * 23 3
(16) Stearic acid 2
(17) Glyceryl stearate 0.5
(18) Cetearyl alcohol 1.5
(19) 2-ethylhexyl paramethoxycinnamate 7
(20) Polysilicone-15 * 24 3
(21) Natural Vitamin E 0.1
(22) Fragrance 0.1
* 22: CARBOPOL 980 (manufactured by LUBRIZOL ADOVANCED MATERIALS)
* 23: KSP-102 (manufactured by Shin-Etsu Chemical Co., Ltd.) Average particle size 30 μm
* 24: PARSOL SLX (manufactured by DSM NUTRITIONAL PRODUCTS)
(Production method)
A: Ingredients (1) to (14) are uniformly mixed.
B: Ingredients (15) to (22) are uniformly mixed and dissolved at 70 ° C.
C: Add B to A and emulsify D: C is filled in a container.
The O / W emulsified daytime beauty essence of Example 17 was excellent in smooth spread and spread and UV protection effect.

Example 18: O / W emulsifying cream (ingredient) (%)
(1) Sodium N-stearoyl-N-methyltaurine 2
(2) Glycerin 5
(3) 1,3-butylene glycol 15
(4) Polyethylene glycol * 255
(5) Disodium edetate 0.05
(6) Sodium monohydrogen phosphate 0.1
(7) Theanine 0.5
(8) Humus extract * 16 20
(9) Remaining amount of purified water (10) Xanthan gum 0.2
(11) (Diphenyldimethicone / Vinyldiphenyldimethicone /
Silsesquioxane) Crosspolymer * 26 2
(12) Silicic anhydride * 27 1
(13) Behenyl alcohol 3
(14) Glycerin fatty acid ester * 28 2
(15) 2-ethylhexyl paramethoxycinnamate 5
(16) Bisethylhexyloxyphenol methoxyphenyl triazine 2
(17) Propylene Glycol Dicaprate 10
(18) Tritridecyl trimeritoate 3
(19) Di (phytosteryl 2-octyldodecyl) N-lauroyl-L-glutamic acid 5
(20) Dilinolate (phytosteryl / isostearyl / cetyl /
Stearyl / Behenyl) 5
(21) Hydrogenated polyisobutene * 29 3
(22) Olive fruit oil 2
(23) Fragrance 0.2
* 25: PEG-1500 (manufactured by Toho Chemical Industry Co., Ltd.)
* 26: KSP-300 (manufactured by Shin-Etsu Chemical Co., Ltd.) Average particle size 5 μm
* 27: HCS 160M5 (manufactured by JGC Catalysts and Chemicals Co., Ltd.) Average particle size 5 μm
* 28: Sunfact GMR-90 (manufactured by Taiyo Kagaku Co., Ltd.)
* 29: Pearl Dream 24 (manufactured by NOF CORPORATION)
(Production method)
A: Ingredients (1) to (10) are uniformly mixed and dissolved at 70 ° C.
B: Ingredients (11) to (23) are uniformly mixed and dissolved at 80 ° C.
C: Add B to A and emulsify D: C is filled in a container.
The O / W emulsifying cream of Example 18 was excellent in smooth spreading and spreading and UV protection effect.

Example 19: W / O emulsifying lip essence (ingredient) (%)
(1) Dextrin palmitate 5
(2) Diisostearyl malate 15
(3) Polyglyceryl triisostearate-2 Remaining amount (4) Vaseline 10
(5) Polybutene * 30 25
(6) Diphenyldimethicone * 31 5
(7) 2-ethylhexyl paramethoxycinnamate 7
(8) Dimethicone * 32 3
(9) Liquid paraffin * 335
(10) Dibutylhydroxytoluene 0.1
(11) Menthol 0.5
(12) Conference 0.5
(13) l-menthylglyceryl ether 0.5
(14) Sage leaf extract 0.01
(15) Mentha extract 0.01
(16) Dipropylene glycol 3
(17) Silicic anhydride * 34 3
(18) Titanium oxide coated mica * 35 0.5
(19) Humus extract * 16 15
* 30: Nippon Oil Polybutene HV-1900F (manufactured by JX Nippon Oil Energy Co., Ltd.)
* 31: KF-54 (manufactured by Shin-Etsu Chemical Co., Ltd.)
* 32: KF-96-100CS (manufactured by Shin-Etsu Chemical Co., Ltd.)
* 33: KLEAROL WHITE MINERAL OIL (manufactured by SONNEBORN)
* 34: Silica microbead P-1505 (manufactured by JGC Catalysts and Chemicals Co., Ltd.) Average particle size 10 μm
* 35: FLAMENCO RED 420C (manufactured by BASF)
(Production method)
A: Ingredients (1) to (10) are uniformly mixed and dissolved at 70 ° C.
B: Ingredients (11) to (16) are uniformly mixed and dissolved.
C: A, B and components (17) to (18) are uniformly mixed.
D: C is emulsified by adding component (19).
E: D is filled in a container at 60 ° C.
The W / O emulsifying lip essence of Example 19 had a smooth spreading and spreading effect and was excellent in UV protection effect.

Example 20: Oil-based lip balm (ingredient) (%)
(1) Polyethylene * 365
(2) Synthetic wax * 375
(3) Beeswax * 385
(4) Remaining amount of cetyl ethylcaproate (5) Polyglyceryl diisostearate-25
(5) Vaseline 10
(6) Hexa (hydroxystearic acid / stearic acid / rosin acid)
Dipentaerythrityl 10
(7) Shea fat 10
(8) Macadamia nut fatty acid phytosteryl 5
(9) 2-ethylhexyl paramethoxycinnamate 5
(10) Polysilicone-1 crosspolymer * 395
(11) Humus extract * 16 3
* 36: PERFORMALENE 500 (manufactured by New Phase Technology)
* 37: CIREBELLE 108 (manufactured by CIREBELLE)
* 38: WHITE BEES WAX (manufactured by Miki Chemical Co., Ltd.)
* 39: KSP-411 (manufactured by Shin-Etsu Chemical Co., Ltd.) Average particle size 12 μm
(Production method)
A: The components (1) to (9) are heated and dissolved, and the components (10) to (11) are added and mixed uniformly.
B: A is filled in a container at 80 ° C. and cooled and solidified.
The oil-based lip balm of Example 20 had a smooth spreading and spreading effect and was excellent in UV protection effect.

Example 21: O / W emulsifying base (ingredient) (%)
(1) Perfluorooctyltriethoxysilane 2% treated fine particle titanium oxide * 40 10
(2) Titanium oxide * 41 3
(3) Bengala 0.1
(4) Yellow iron oxide 0.5
(5) Black iron oxide 0.02
(6) Polysilicone-22 * 425
(7) Polyethylene sorbitan monooleate (20EO) 1
(8) Sorbitan sesquioleate 0.5
(9) Lecithin 0.3
(10) 1,3-butylene glycol 5
(11) Polyoxyethylene methylglucoside 2
(12) Glycerin 5
(13) Carboxyvinyl polymer * 43 0.5
(14) Alcaligenes-producing polysaccharide 0.5
(15) Remaining amount of purified water (16) Humus extract * 16 20
(17) Triethanolamine 0.5
(18) 2-ethylhexyl paramethoxycinnamate 8
(19) Liquid paraffin * 44 3
(20) Dimethicone * 45 2
(21) Setostearyl alcohol 0.3
(22) Behenyl alcohol 0.2
(23) Glyceryl stearate 0.3
* 40: TTO-51 (A) (manufactured by Ishihara Sangyo Co., Ltd.) Average particle size 0.02 μm
* 41: ST-730EC (manufactured by Titan Kogyo Co., Ltd.) Average particle size 0.5 μm
* 42: KSP-441 (manufactured by Shin-Etsu Chemical Co., Ltd.) Average particle size 12 μm
* 43: CARBOPOL 940 (manufactured by LUBRIZOL ADOVANCED MATERIALS)
* 44: HYCOAL K-350 (manufactured by Kaneda)
* 45: KF-96L 2CS (manufactured by Shin-Etsu Chemical Co., Ltd.)
(Production method)
A: Ingredients (1) to (12) are uniformly mixed and dispersed.
B: A and components (13) to (17) are uniformly mixed and dispersed.
C: Ingredients (18) to (23) are uniformly mixed and dissolved at 80 ° C.
E: D to be emulsified by adding C to D: B is filled in a container.
The O / W emulsified base of Example 21 was excellent in smooth spreading and spreading and UV protection effect.

Example 22: Ointment (ingredient) (%)
(1) Stearyl alcohol 18.0
(2) Japan wax 20.0
(3) Polyoxyethylene (20 mol) monooleic acid ester 0.3
(4) Tocopherol 0.1
(5) Vaseline 40.0
(6) 2-ethylhexyl paramethoxycinnamate * 6 0.5
(7) Pentaerythrityl tetraisostearate 1.0
(8) Silicic anhydride * 13 0.5
(9) Remaining amount of purified water (10) Glycerin 10.0
(11) Humus extract * 16 0.5
(Production method)
A: Ingredients (1) to (8) are uniformly mixed at 70 ° C.
B: Ingredients (9) to (11) are heated to 70 ° C.
C: B was added to A and emulsified to obtain an ointment.
The ointment of Example 22 had a smooth spreading and spreading effect and was excellent in UV protection effect.

Claims (7)

The following components (A) to (C);
(A) Corrosive soil extract (B) Organic UV absorber and / or metal oxide powder (C) Spherical powder with an average particle size of 5 to 30 μm ( however, polymethylsilsesquioxane, (HDI / tri) (Excluding methylolhexyl lactone) crosspolymer or alkyl polyacrylate )
A skin external preparation or cosmetic containing. The first aspect of claim 1 is that the humus extract of the component (A) contains 100 mg / L or more of humic acid when dissolved or suspended in water so that the extract concentration is 0.5% by mass. The listed external preparations for skin or cosmetics. Claimed that the component (A) humus extract contains 0.1 to 100 mg / L of fulvic acid when dissolved or suspended in water so that the extract concentration is 0.5% by mass. Item 2. The external preparation for skin or cosmetics according to Item 1. The skin external preparation or cosmetic according to any one of claims 1 to 3 , wherein the average particle size of the component (C) is 5 to 15 μm. The skin external preparation or cosmetic according to any one of claims 1 to 4 , wherein the component (C) is silicic anhydride. The skin external preparation according to any one of claims 1 to 5 , wherein the content mass ratio of the component (A) to the component (C) is (A) :( C) = 1: 1 to 1: 100,000. Cosmetics. The skin external preparation or cosmetic according to any one of claims 1 to 6 , wherein the skin external preparation or cosmetic is an emulsion.