JP5967792B1 - Medicine bag medication management device, medicine bag medication management method, and program - Google Patents

Abstract

An object of the present invention is to detect forgetting to take a medicine based on time-series fluctuations in the weight of a medicine box containing a plurality of medicine bags. A medicine bag dosage management apparatus 200 includes a fluctuation judgment unit 209 for receiving a weight fluctuation of a medicine box by a weight sensor 201 and a time stamp by a clock 202, a meal / dose registration unit 205, a patient ID / medicine dosage unit. Based on the registration unit 206 and the determination criterion registration unit 207, it is determined whether or not there is a forgotten or partially missed dose of the medicine. An information transmission device 300 for transmitting to a patient is provided. [Selection] Figure 3

Description

  The present invention allows a patient to use drugs in various dosage forms from a plurality of medical institutions and pharmacies from medicine bags, PTP packaging, wrapping paper, liquid container, injection vials, external preparation tubes, etc. Based on the above, the medicine bag medication management device, the program, the information transmission device, and the advance management for managing the proper medication from this medicine bag (here, all containers and bags for all dosage forms) The present invention relates to an input / output unit for registering information and recording information to be measured.

  It is said to be medication adherence. In the past, it was natural for doctors to decide on a treatment policy and follow patients, but today, patients are difficult to take, especially when they are taking medicines at home, where medical staff cannot reach them. Because of the many types of medicines prescribed and the timing of taking them, forgetting to drink can lead to the need for adherence. It is the patient's own need to monitor that the patient is taking medication as prescribed by the doctor, and there is a need for the government, medical institutions and pharmaceutical companies.

  In the past, in order to prevent home patients from forgetting to take medicine, the simplest mechanism has been sold in cases that can be subdivided into 7 days a week.

  In the United States, on the other hand, even if it is a prescription drug, tablets are often sold in bottles, or because of the ease of transfer, electric pill dispensers are sold. A mechanism is used in which the necessary time is monitored and the time is monitored, and the necessary tablets are taken out electrically at a predetermined time. Non-Patent Document 1 is an example. In Japan, a dispenser as described in Non-Patent Document 2 has been announced.

  As software that contributes to the management of medication in a broad sense, there are many softwares that input or notify the implementation of medications using smartphone software, and sound an alarm at the time of medication. Non-patent document 3 is an example.

  A mechanism has been announced in which a medicine is sealed in a special roll each time by a packaging machine, wound around a drum and electrically opened, and Patent Document 1 is an example.

  Patent Document 2 is an idea of monitoring the dose of the whole amount of medicine at that time by opening and closing the medicine box without sticking to one tablet or one drop of medicine. In addition to this, the timing of medication is monitored at a meal event, and the sensor of the table chair detects that it has touched the table.

JP2015-16324 JP 2015-47390

Remote Medication Management System, http://www.inrangesystems.com/ Drug case with drug promotion and management functions, http://jpn.nec.com/techrep/journal/g14/n01/pdf/140112.pdf Electronic medicine notebook, http://www.nichiyaku.or.jp/e_okusuritecho/

  For simple one-week pill cases, there are various dosage forms and packages such as PTP packaging and liquids for drugs, so there are limited opportunities to use such cases and the possibility of storing the entire amount in the case. In addition, refilling is cumbersome for the elderly, and there is no function to alert each dose during the day.

  Even if it is a large machine like in the United States, it should be done by familiar medical staff, but at the patient's home there is a risk of mistakes and mistakes in transferring drugs, and the number of types of drugs is limited, The dosage form is also limited to tablets. Machine functions are not used when going out or traveling. The non-patent document 2 dispenser in Japan is also unrealistic in the light of the actual taking environment in Japan, such as the limited number of tablets and medicines.

  Smartphone medication management software is cumbersome to enter medication every time, and it seems that there are few patients who enter frequently, and that patients who enter frequently do not forget to drink in the first place. Differences in fundamental needs and solutions are observed. Also, if the alarm is sounded mechanically several times a day, there is a risk that the alarm will be overwhelmed or over-accustomed and the alarm will be ignored or not noticed.

  The method of pre-sorting into rolls with a packaging machine must be sealed at a prescription pharmacy, and the cost, medical fee system, and available drug dosage forms are limited. It can be imagined that the opportunities for use are very limited. In addition, it is not possible to objectively verify whether or not a mechanism that only takes and rolls a number of times or days for traveling or going out is taken. There is a way to carry this machine, but it is cumbersome.

  Management focusing on the opening and closing of the medicine box, as a problem, it can not be determined that the medication has been carried out only by opening and closing the medicine box, and the meal event is monitored with a sensor on the table chair, but in reality there is a possibility that it does not necessarily eat There is a possibility of sitting in a chair outside of a meal. Even in this case, it is impossible to deal with events such as going out and traveling.

  In the first place, the appropriateness of monitoring at the timing of meals is inadequate, and prescription and pre-meal instructions are certainly given in the prescription, but this is based on the assumption that meals are scheduled on time, the most important is Keeping the blood concentration of the drug as constant as possible. For example, if you don't have breakfast, you don't have to take it in the morning, or if you should eat lunch at 11:00 or 14:00 and take the medicine at the appropriate time. It is necessary to follow prescriptions before and after meals after setting meal times. FIG. 1 shows the ideal transition of the blood concentration of such drugs.

  FIG. 2 is an image of a medicine bag of a home patient with chronic illness. Hold a large number of medicine bags provided by multiple medical institutions or pharmacies, different dosage forms, various dosage patterns, and medicines purchased at OTC other than prescribed medicines, and take them daily. It can be said that there is no realistic machine that can set this and manage medication.

  In order to solve the above-mentioned problems, the drug bag medication management device according to the present invention has a time series of the weight of a drug box and a drug box that simply puts all dosage forms, packaging, and drug bags including liquid drugs and external preparations together. A weight sensor to be monitored, a watch, a judgment standard registration for judging the weight fluctuation pattern and determining what the weight fluctuation means, a fluctuation judgment section for judging by the standard and measurement information, It is characterized by having an information transmission device that expresses an alert in the case of forgetting to drink, and a recording unit for status of weight transition and what happened.

  In order to solve the above problem, the medicine bag medication management apparatus according to the present invention registers a part for registering meal time and medication timing, a patient ID, and a unit weight for each individual medication associated with it. And a part for registering a message when it is determined that the user has forgotten to drink, and a part for registering a transmission / reception destination and transmitting / receiving, and is used for calculation and recording of a variation determination part referring to the above-mentioned determination criteria. To do.

  In addition, in order to solve the above-mentioned problem, the variation determining unit according to the present invention monitors the weight before taking, the irregular variation in weight during taking, the weight after taking, and forgetting to drink due to the time series fluctuation of the medicine box weight. Detecting, transmitting and recording the status, so that no matter how the medicine to be measured is stored in any medicine bag, there is no need to detect or register the weight of the medicine bag itself .

  Further, in order to solve the above-mentioned problem, the variation determination unit according to the present invention is based on the time series variation of the medicine box weight, whether the medicine bag was taken out due to the trip out, whether the trip out was finished and the medicine bag was returned, Alternatively, the status is recorded by detecting whether or not the medicine bag is used up.

  Further, in order to solve the above problem, the variation determination unit according to the present invention is configured such that, due to time-series fluctuation of the drug box weight, the empty medicine bag is discarded, or the medicine prescription is finished and the medicine bag is discarded, or There is a re-prescription of a medicine that is temporarily left untreated, and the status is recorded by detecting whether the number of medicine bags has become two or the prescription has increased and the number of medicine bags has increased.

  In order to solve the above-mentioned problem, the registration / recording input / output unit according to the present invention is an external program and communicates with the information transmitting / receiving unit in the apparatus, and uses the patient ID as a key to provide necessary registration information. It can be sent from outside such as pharmaceutical companies, prescription pharmacies, medical institutions, etc., and medical staff etc. can see the records in the device to monitor the progress of taking medication, compare weight in a long time series, and forget to drink It is a mechanism that can tell how much did not exist, and is characterized by being able to make use of it for medication instruction.

  In addition, in order to solve the above problems, the registration / recording input / output unit according to the present invention can be input and referred to from a plurality of pharmaceutical companies, medical institutions or pharmacies, and can be used together with the overall information of the patient's medication. It is possible to understand the situation and make use of it for medication instruction, and to obtain the difference in the efficacy of the medicine by drinking the medicine as epidemiological information from the feedback of the dosage information of multiple patients and the examination information from the medical institution. Features.

  According to the present invention, at home, holding a large number of medicine bags provided from a plurality of medical institutions or pharmacies, different dosage forms, various dosage patterns, medicines purchased at OTC other than prescribed medicines, etc. You can put them in a medicine box in a lump and manage forgetting to drink, and medical staff can give instructions on medication.

It is an image that the blood concentration should be kept as constant as possible on the assumption that the timing of taking does not depend on the meal but the meal time is fixed. It is an image of a typical medicine bag taken at home to be managed by the present invention. It is a block diagram which shows the physical perspective view of the medicine bag medication management apparatus which concerns on embodiment of this invention, the structure of the content, and the structure of an information transmission apparatus. This is an image of the time series of weight taking four times a day as an example, and the portion that fluctuates up and down for a short period of time means that you are touching a medicine bag while taking. This is an image of the time-series transition of weight, taking as an example the case of taking out a medicine bag on the trip, returning it, and using it up. This is an image of the time series of weight, taking the increase and disposal of medicine bags as an example. This is a logic flow showing the mechanism of time monitoring and weight monitoring, which is the basis of the mechanism of the fluctuation judgment unit. FIG. 8 is a continuation flow of FIG. 7 of weight monitoring, which is the basis of the mechanism of the fluctuation determination unit. It is an image figure which can confirm whether there is a contraindication of drinking by allowing a plurality of pharmaceutical companies, medical institutions, or pharmacies to refer to each other with medication unit registration information.

  Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings.

(First embodiment)
FIG. 3 is a block diagram showing the configuration of the entire system centering on the medicine bag medication management apparatus according to the first embodiment of the present invention. The system shown in FIG. 3 includes a medicine bag medication management device 200 and an information transmission device 300 attached to a medicine box 100 for storing medicine bags, and a screen display 400, a speaker 500, and external information input / output attached to the medicine bag medication management device 200. A terminal 700, a power connection terminal 800, and a registration / recording input / output unit 600, which is an input / output program placed outside from the medicine bag medication management apparatus 200 through an information network, are provided.

  The medicine box 100 has such a size that, for example, various medicine bags from a plurality of medical institutions or pharmacies and medicines purchased at OTC can be put together by elderly people with chronic illness at home.

  The medicine bag medication management apparatus 200 includes a weight sensor 201, a clock 202, a weight recording unit 203 that records the measured weight, a status recording unit 204 that records a patient's medication status, a patient ID, a scheduled meal time, and the like. Meal / dose registration unit 205 with the time to be taken, dose unit registration unit 206 for registering the dose, dose pattern and duration of each individual drug, what does the weight change mean? Judgment criterion registration unit 207 having a criterion for judgment, message registration unit 208 having a message to be transmitted to a patient, and determining what event has occurred based on recorded information and pre-registered information A change determination unit 209 to be recorded in the recording unit, a transmission / reception destination registration unit 210 having a transmission / reception destination address when communicating with the outside through the change determination unit, Comprising information transceiver unit 211 with reference to the above information receiving the output or input information to the registration and recording output unit to be placed in the information transmission apparatus or externally, and a power supply unit 212.

  The information transmission device 300 finally receives a message transmission / reception unit 301 that receives message information from the information transmission / reception unit in the medicine bag medication management device and receives power supply, and a message that is connected to the message transmission / reception unit and displayed on the screen display. A screen creation unit 302 for creating a message, and a voice synthesis unit 303 connected to the message transmission / reception unit for transmitting a message by voice from a speaker.

  The weight sensor 201 is capable of discriminating the weight even with a drop of eye drops (0.03 g) or even the smallest tablet (0.05 g) with an accuracy of 0.01 g, which is inexpensively available on the market, and detects the weight and fluctuation of the medicine box 100. And transmitted to the fluctuation determination unit 209.

  The clock 202 has a precision in units of seconds that is available on the market at a low price, and transmits the time as a time stamp to the fluctuation determination unit 209.

  The weight recording unit 203 records the weight of the medicine chest 100 according to the determination of the variation determination unit when necessary based on the information of the variation reference registration unit and the meal / dose registration unit.

  The status recording unit 204 records the situation of the patient's medication, together with a time stamp, when necessary. The types of status are: before taking (g), when taking (the weight fluctuates because it touches the medicine box. It is determined that the dose is taken when the dose changes, and waits for n minutes. By monitoring the weight difference between period t-1 and period t-1 for 5 seconds, it can be determined that it is taking when fluctuations continue), after taking (g) (after waiting n minutes after being detected as taking) For this reason, the weight before taking g-the weight after taking g = the actual taking weight at that time), taking out the medicine bag (for going out of the trip, when returning it later, when drinking it up and discarding the medicine bag) Yes, it can be finally determined by the weight monitoring explained in the flow), return the medicine bag, discard the medicine bag (there is an empty medicine bag disposal or a medicine bag disposal at the end of some medicines, but the unique weight for each dose) Because it is managed, there is no need for classification), medicine Increase of bags (there is leftovers and temporary addition of medicine bags or cases of taking medicines and medicine bags may be increased, but there is no need for classification because the unique weight is managed for each dose), these 7 statuses There is.

  The meal / dose registration unit 205 presupposes that the prescription and post-meal instructions are given on the prescription of the drug, and this is based on the premise that the meal is scheduled on time. Since the concentration is to be kept as constant as possible, here, the meal time that the patient should be is registered, and the scheduled time at the time of taking (the timing of taking) is calculated and recorded by a predetermined formula. Usually taken before breakfast (t1 '), after breakfast (t1), before lunch (t2'), after lunch (t2), between meals (morning-noon) (t1-2), between meals (day-evening) ) (T2-3), before dinner (t3 '), after dinner (t3), and before going to bed (t4) can be preferentially prescribed, but the patient's meal time is first registered and scheduled for taking Register the time in numerical form using a formula. Here, breakfast time (m1 = XX: XX), lunch time (m2 = XX: XX), dinner time (m3 = XX: XX), bedtime (m4 = XX: XX) Takes a value between hours. For example, if you have breakfast at 08:00, lunch at 12:00, dinner at 19:00, and sleep at 24:00, the estimated time of taking the time is calculated before the breakfast (t1 ') = 08: 00-00: 30, after breakfast (T1) = 08: 00 + 00: 30, before lunch (t2 ') = 12: 00-00: 30, after lunch (t2) = 12: 00 + 00: 30, between meals (morning-noon) (t1- 2) = (12: 00-08: 00) / 2 + 08: 00, Meals (daytime-evening) (t2-3) = (19: 00-12: 00) / 2 + 12: 00, before dinner ( t3 ') = 19: 00-00: 30, after dinner (t3) = 19: 00 + 00: 30, before going to bed (t4) = 24: 00-00: 30.

  The patient ID / medicine unit registration unit 206 includes a unique ID symbol number for each patient using this medicine bag medication management device, each medicine taken by the patient, the type, dosage form, and effective of each individual medicine. One dose weight for each prescription pX unique to the combination of ingredients, the timing of taking (whether it is t1 ', t1 or t1, t2, t3 and 3 times) Have information. That is, for each drug prescription (p1, p2, p3,---), pX = (Xg, tX, tX, tX,---, plus XXXX year XX month XX day tX to XXXX year XX month XX days tX) is placed in the registration department. For this reason, the total scheduled dose for a given dose is calculated as the total Xg of all medications taken at that time. With this master information, even when drug prescriptions are added or decreased, the unique scheduled dose can be calculated as the total dose weight calculated from the master information registered as a medication unit each time a dose is taken. The missed dose is detected based on the difference in the weight of the medicine box that is actually measured and detected, that is, in comparison with the actual dose.

  The judgment standard registration unit 207 registers a standard for judging what event the time series fluctuation of the weight detected by the weight sensor and recorded in the weight recording unit through the fluctuation judgment unit means. Also register n for n minutes waiting to measure the weight difference of the drug at irregular weight fluctuations. The contents of this standard will be described later.

  The message registration unit 208 registers a message to be transmitted to the patient when forgetting to drink is detected.

  Based on the mechanism registered in the criterion registration unit 207, the variation determination unit 209 refers to the weight and time-series variation status from the weight sensor 201, refers to the time information from the clock 202, and records the weight. In addition to recording the weight and time stamp in the unit 203, with reference to the registration information unique to the patient in the meal / dose registration unit 205 and the patient ID / drug unit registration unit 206, what event occurs due to the weight fluctuation And the generated status and time stamp are recorded in the status recording unit 204. The contents of this determination logic will be described later. Further, referring to the transmission / reception destination registration unit 210, the communication function of the information transmission / reception unit 211 is used to communicate with the patient and an external input / output program.

  The transmission / reception destination registration unit 210 registers the internal address of the message transmission / reception unit 301 of the information transmission apparatus and the address of the external registration / recording input / output unit 600.

  The information transmission / reception unit 211 inputs / outputs registration information and recording information to / from the message transmission / reception unit 301 of the information transmission apparatus and the external registration / recording input / output unit 600 via the variation determination unit 209.

  The power supply unit 212 supplies power to each component of the medicine bag medication management device 200, the screen display 400 and the speaker 500 provided therein, and each component of the information transmission device 300 to drive it.

  The information transmission apparatus 300 includes a message transmission / reception unit 301, a screen creation unit 302, and a speech synthesis unit 303.

  The message transmission / reception unit 301 receives message information about forgetting to drink from the medicine bag medication management apparatus 200 (information transmission / reception unit 211). In addition, a necessary power source in the information transmission device is received from the power source unit 212.

  The screen creation unit 302 finally creates an image that is actually displayed on the screen display.

  The voice synthesizer 303 creates an analog signal that is actually transmitted to the patient through a speaker.

  The screen display 400 displays an image of the message created by the screen creation unit 302.

  The speaker 500 sounds an analog voice signal of the message synthesized by the voice synthesis unit 303.

  The registration / record input / output unit 600 is externally communicated with each component that performs recording or registration in the medicine bag medication management apparatus 200 via the information transmission / reception unit 211 and the variation determination unit 209, and registers information Or refer to the recorded information.

  The external information input / output terminal 700 is a physical connector used when the information transmitting / receiving unit 211 communicates with an external registration / recording input / output unit 600 via a network.

  The power supply connection terminal 800 is a physical outlet when the power supply unit 212 receives power from the power network through AC / DC conversion.

  FIG. 4 shows the time series fluctuation of the weight when the total weight of the medicine bag stored in the medicine box 100 according to the present invention is detected by the weight applied to the weight sensor 201 and recorded in the weight recording section 203 via the fluctuation recording section 209. It is an image, and when taking four times from t1 to t4, the time is shown as an example. As described above, “when taking” may have a patient-specific pattern selectively among 9 times at most in one day, but here it is shown as 4 times for easy understanding. In the pre-medication status, the weight does not change for a certain period of time, but since the patient randomly touches the medicine bag when taking the medicine, the weight applied to the weight sensor fluctuates irregularly in a short time. When n minutes of medication is completed and after medication, the change does not change for a certain period of time, and the status before the next medication is recorded after status recording after medication. The logic flow of the mechanism for judging this from the weight will be described later.

  FIG. 5 shows the time series fluctuation of the weight when the total weight of the medicine bag stored in the medicine box 100 according to the present invention is detected by the weight applied to the weight sensor 201 and recorded in the weight recording section 203 via the fluctuation recording section 209. It is an image of another pattern. Image when the weight on the weight sensor fluctuates greatly when the patient travels or goes out, such as by cutting out a part of a medicine bag or container, a part of a medicine bag or a part of a PTP package, or taking out only a tablet or a package It is. Take out the medicine bag when traveling or going out and return the rest to the medicine box when returning home, and take out the medicine bag (in this case, typically only PTP packaging or sachet cut-out required) when traveling or going out The image is expressed as if it had been drunk when it returned from. The logic flow of the mechanism for judging this from the weight will be described later.

  FIG. 6 shows the time series fluctuation of the weight when the total weight of the medicine bag stored in the medicine box 100 according to the present invention is detected by the weight applied to the weight sensor 201 and recorded in the weight recording unit 203 via the fluctuation recording unit 209. It is an image of another pattern. If the number of sachets increases, this includes adding a new sachet of the same pill that was newly supplied to the old sachet with the remaining pills and temporarily having two sachets for that pill, The dose may increase and the medicine bag may increase. Also, when discarding a medicine bag, this may be when an empty medicine bag is discarded or when some medicines are prescribed and taken and then the medicine bag for that medicine is discarded.

  FIG. 7 is a logical flow of judgment of the fluctuation judgment unit 209 showing two mutually independent mechanisms forming the basis of the first embodiment of the present invention, that is, a mechanism of time monitoring and weight monitoring. In the time monitoring, the fluctuation determination unit 209 determines the information from the clock 202 and the information of the registration unit 205 at the time of eating / taking, continuously monitoring whether or not it is the timing of taking, and in the case of taking time, the patient Determines whether the post-dose status is recorded in the status recording unit 204, and if there is no post-dose status, a message of forgetting to drink is transmitted from the information transmission device 300 to the patient, If there is a record but the actual dose is not enough for the scheduled dose at that time, a message that a part of the dose is forgotten is sent from the information transmission device 300 to the patient. With this mechanism, you can avoid alarms when you haven't forgotten to drink, and you can avoid alert fatigue and alert habituation by simply monitoring the taking status recorded from weight fluctuations. The other weight monitoring in FIG. 7 is to monitor the information of the weight sensor 201 every second to every 5 seconds, continuously monitoring whether there is any variation in the dose when the patient irregularly touches the medicine box at the time of taking, In the case of time variation, refer to the information of the patient ID / medication unit registration unit 206 and the meal / dose registration unit 205 for the expected dose for that time, wait for the registered n minutes, and then take the dose It is judged whether the actual dose, which is the weight difference before and after the fluctuation, is equal to or less than the planned dose, and if so, the post-dose record is recorded in the status recording unit 204 and the next dose is recorded. Also record your pre-dose status. Here, the case where the actual dose is equal to or less than the planned dose will be described later with reference to FIG.

  FIG. 8 shows that when the actual dose is equal to or less than the planned dose, it can be determined that the weight has decreased more than the dose or, on the contrary, the weight has increased. Is shown in a logic flow. The increase in weight means an increase in the medicine bag, and the status of the medicine bag increase is recorded in the status recording unit 204. The weight reduction means taking out the medicine bag, and the status is recorded in the status recording unit 204. In this case, after taking out the medicine bag or a part thereof on a trip or going out, it is an interval with no weight change for a while. Since there is a possibility of simply discarding an empty medicine bag or both, the logic of whether or not there is a variation when taking is repeatedly monitored every second to every 5 seconds. When the next dose variation comes, refer to the unique scheduled dose for that time, wait n minutes, and if the actual dose, defined as the difference between before and after the change, has increased, go out of the trip It is determined that the removed medicine bag has been returned, and the status of returning the medicine bag is recorded in the status recording unit 204. When the actual dose, which is defined as the difference between before and after the change, weighs less than or equal to the planned dose, it can be determined that there was a normal dose, so the status of taking out the medicine bag was recorded in the previous step. However, at this point, it can be determined that the empty medicine bag has simply been discarded or that some medicines have been prescribed and taken and the medicine bag has been discarded. To do.

  Thus, according to the first embodiment of the present invention, the specific scheduled dose of each dose is grasped, and the difference in the weight of the entire medicine box is monitored without being influenced by the weight of the medicine bag itself. By grasping the actual dose, medication management based on a medicine bag can be performed, and as long as the medicine is taken as scheduled, it is not necessary to issue an alert, so it is possible to prevent alert fatigue and alert familiarization, travel outing and medicine bags You can grasp the status of taking out, returning, and discarding, and you can determine whether you are actually taking it by weight and registration information only, whether it is a change in the weight of the medicine bag, It can be highly accurate information. As mentioned above, a medicine bag accepts the use of medicines of all dosage forms from medicine bags, PTP packaging, wrapping paper, liquid container, injection vials, external preparation tubes, etc. Being able to manage liquids, injections, or drops of eye drops in the environment is an effective means of solving the long-standing problem of medication adherence.

(Second Embodiment)
In FIG. 9, the information transmitting / receiving unit 211 of the medicine bag medication management apparatus 200 according to the second embodiment of the present invention is connected to and communicated with a plurality of registration / recording input / output units 600 via the network such as the Internet. FIG. 9 is a block diagram, and is added to the lower part of FIG. 9 for easy understanding of the use of the drug prescription information registered in the patient ID / medication unit registration unit 206 among the components of the drug bag medication management apparatus 200. Since the other components of the medicine bag medication management apparatus 200 are the same as those in the first embodiment, the description thereof is omitted.

  In the second embodiment, an information sharing contract is concluded between a plurality of pharmaceutical companies or medical institutions or pharmacies that use the registration / record input / output unit 600 placed outside, and the information on the drug prescription is stored. It is assumed that cross-reference can be made. A pharmaceutical company, medical institution, or pharmacy registers its own drug prescription information in the patient ID / medicine unit registration unit 206. However, based on the information sharing agreement, the other pharmaceutical company, medical institution, or pharmacy registers the patient ID / drug Information on the drug prescription registered in the dosage unit registration unit 206 is obtained on the registration / recording input / output unit 600 side through communication with the information transmission / reception unit 211 via the variation determination unit 209.

  The pharmaceutical company, medical institution, or pharmacy will not accept a contraindication for the patient's ingestion between the drugs prescribed by the institution and other institutions and taken by the patient during the prescribed period, or from a different medical institution or pharmacy. It is possible to check whether there are duplicate medicines with the same medicinal properties.

  In Japan, after a drug is administered to a patient, there is a post-marketing survey in which a medical institution monitors the effect of taking the drug on the patient, which is performed by a pharmaceutical company and a medical institution. Even though clinical trials are conducted in clinical trials, they are performed with a limited number of samples under limited conditions. Therefore, in order to grasp more than expected or unexpected side effects and infectious diseases after manufacturing and sales, According to the “Basic Policy on Manufacturing Approval of Pharmaceuticals” (Notification of the Director of Pharmaceutical Affairs, Ministry of Health and Welfare) in 11992, new drugs were required to report side effects for 2 years after approval. The survey consists of a “re-examination system and periodic safety report” for new drugs, a “re-evaluation system” for all drugs, and a “side-effect / infectious disease report system” that constantly monitors safety. One exists. According to the second embodiment of the present invention, the pharmaceutical prescription status of a plurality of patients and the information of post-marketing survey from the medical institution in charge, the pharmaceutical company and the medical institution are more than expected or unexpected side effects and infectious diseases. Epidemiological information can be obtained about the situation, especially to confirm whether there is a difference in the efficacy of the drug by drinking.

  The timing at which the pharmaceutical company or medical institution or pharmacy obtains the prescription information registered by the other pharmaceutical company or medical institution or pharmacy in the patient ID / medication unit registration unit 206 is arbitrary, but the patient ID / drug This user connects an appropriate monitoring program to the dose unit registration unit 206, so that an alert is sent when any addition, termination, or deletion is made to the patient ID / drug unit registration information of the patient. Can be raised.

DESCRIPTION OF SYMBOLS 100 Medicine box 200 Medicine bag medication management apparatus 201 Weight sensor 202 Clock 203 Weight recording part 204 Status recording part 205 Meal and taking time registration part 206 Medication taking unit registration part 207 Judgment standard registration part 208 Message registration part 209 Fluctuation judgment part 210 Transmission destination Registration unit 211 Information transmission / reception unit 212 Power supply unit 300 Information transmission device 301 Message transmission / reception unit 302 Screen creation unit 303 Speech synthesis unit 400 Screen display 500 Speaker 600 Registration / recording input / output unit 700 External information input / output terminal 800 Power connection terminal

Claims (7)

A weight sensor for weighing the medicine box;
Time series fluctuations in the weight sensed by the weight sensor, the status of the pre-dose, to determine whether which of the status of the status and after taking in taking a variance determining unit for recording the determined status ,
An information transmission device that transmits the message to the patient only when it is determined that the user has forgotten to take the medicine,
A medicine bag medication management device Ru with a,
Before Symbol fluctuations determination unit, constantly monitoring the series change time of the weight,
Time series variation of the weight is
After the start of monitoring, it is determined that the time series period A in which there is no change in weight until the first change in weight is detected is the status before taking,
A time series period B in which the weight from when the first fluctuation is detected to before the lapse of time n fluctuates irregularly is determined as a status at the time when the patient irregularly touches the medicine bag,
After the elapse of time n, a time series period C without a change in weight until the next change in weight is detected is determined as a status after taking,
Replacing “after the time n” and “next weight fluctuation” in the period C with “after monitoring start” and “first weight fluctuation” in the period A, respectively, Consider A,
Judge the period A as the status before taking,
The period B is determined as a status when the patient is taking a drug bag irregularly,
Repeatedly determining the period C as a status after taking,
In the set of periods A to C, the weight difference obtained by subtracting the weight detected in the period C from the weight detected in the period A is determined as the actual dose in the set of periods A to C. > Medicine bag medication management device characterized by that. Before Symbol fluctuations determination unit refers to the scheduled time at the time of dosing, which is calculated from the registration of the patient's diet time,
By referring once and taking the weight of you take in the medication prescription of the patient, the time of taking the drug, and dose duration of the drug,
The sum of all drug formulation of the dosage weight the based on the drug formulation in the dosage period and during the taking, grasped as planned dose to be taken in the time taken and the taking time, according to 請 Motomeko 1 Medicine bag medication management device. Before Symbol fluctuations determination unit monitors the time of each dose from the scheduled time for the watch and clothes,
During dose was monitored, with reference to whether status after the taking is recorded,
If the post-dose status is not recorded, it is determined that you have forgotten to drink,
Wherein the actual dose has been recorded in the status of after taking it, if you do not have enough in the planned dose at the time of the taking, it is determined that there is some drinking forget,
If the patient decides that he / she has forgotten to drink or partly forgets to convey the message to the patient,
The medicine bag medication management device according to claim 2 . When the weight difference becomes negative ,
Drug remaining and prescription of either or drug new bag with the same drugs that are newly supplied to the medicine bag of the former is added taking increases medicine bag is recorded to determine the status of the increased claims 1 to 3 The medicine bag dose management method according to any one of the above . When the weight difference exceeds the planned dose, it is judged and recorded as the status of taking out the medicine bag,
Waiting for the subsequent first heavy amount of variation,
If the weight difference for the weight fluctuation is negative, it is determined that the medicine bag is returned and recorded,
Lever cry weight difference of the weight variation does not exceed the said predetermined dose, of not drugs drinking taken bag either one of claims 2-4 for recording is determined not to be returned to extraction sachets How to take medication. On the computer,
Storing the patient's meal time, the dose weight of one medicine taken in each medicine prescription of the patient, and the duration of the medicine;
Step 2, referring to the meal time of the patient stored in Step 1, and calculating the scheduled time of taking the medicine of each medicine prescription of the patient as the time of taking the medicine;
  The medication dose and the medication duration stored in step 1;
  The sum of the dose weights for all drug prescriptions based on the dose of the drug calculated in step 2,
  Calculating as a scheduled dose to be taken at the time of taking the medicine and during the taking period of the medicine;
Step 4 for constantly monitoring the time n and the weight sensor for weighing the medicine box, and memorizing the time series fluctuation of the detected weight, and
  Referring to the time n and the time series variation stored in step 4,
  The period A from the start of monitoring until the first change in weight is detected is determined as the status before taking,
A period B from the time when the first fluctuation is detected to before the lapse of a predetermined time n is determined as a status that the patient is taking the medicine bag irregularly,
The period C after the elapse of time n until the next change in weight is detected is determined as the status after taking,
  Replacing “after the time n” and “next weight fluctuation” in the period C with “after monitoring start” and “first weight fluctuation” in the period A, respectively, Consider A,
  Judge the period A as the status before taking,
  The period B is determined as a status of the patient taking the medicine bag irregularly,
  Repeatedly determining the period C as a status after taking,
  Step 5 for determining a weight difference between the weight detected in the period A and the weight detected in the period C as an actual dose in each set of the periods A to C.
A drug bag medication management program that runs. In addition to the computer,
  Determining that the actual dose is not enough for the scheduled dose at the time of the dose and that there is a forgotten or partially missed dose; and
  Displaying the decision as a message to the patient, 7,
The medicine bag medication management program according to claim 6 which is made to execute.