JP5851258B2 - Aseptic bonding equipment - Google Patents

Description

  The present invention relates to an aseptic joining apparatus for thermoplastic resin tubes, and in particular, for example, a tube on the patient's peritoneal catheter side used for peritoneal dialysis and a dialysate tube of a peritoneal dialysate bag are heated in a sterile state. The present invention relates to an aseptic joining apparatus for melt joining.

  Peritoneal dialysis is a method in which about 2 liters (in the case of an adult) of dialysis solution is put into the abdominal cavity using a tube embedded in the abdominal cavity of a patient, and water and waste products in the body are removed through the peritoneum. After a few hours, dialysate in the abdominal cavity is placed in a drain bag and discarded, and replaced with fresh dialysate. As a result, the dialysate was injected into the abdominal cavity surrounded by the peritoneum, and the dialysate was transferred to the dialysate through unnecessary waste and water in the peritoneal membrane while the dialysate was stored for a certain period of time. Thereafter, the dialysate can be taken out of the body to purify the blood.

  The aseptic joining device is a device that automatically melts two tubes of the same thickness, for example, and automatically joins them in a sterile state. There is no concern about bacterial contamination during joining, and the sterility of the dialysis fluid and the like in the tube and bag can be maintained. The joining of the two tubes can be performed in an aseptic condition using a wafer for heat fusion pressure welding (see Patent Document 1).

Japanese Patent No. 2710038

  In the aseptic joining apparatus, the two tubes are sandwiched and fixed in a portion where the tube in the casing is fused and joined, and then the portion where the tube is fused and joined is closed with a lid. The wafer is positioned at the portion where the two tubes are fused and joined. After closing the lid, the two tubes are melted by a heated wafer, and the fused ends of the two tubes are replaced and joined.

By the way, when a wafer heats and melts two tubes, the two tubes may not be sufficiently melted by heating. For this reason, the user may not be able to perform peritoneal dialysis.
An object of the present invention is to provide an aseptic joining apparatus that can always surely melt and join two tubes.

  In the aseptic joining apparatus of the present invention, the first tube and the second tube are fused while the first tube and the second tube are fixed, and the melted end of the first tube and the second tube are fused. An aseptic assembling apparatus for exchanging and joining the ends, a housing for fixing the first tube and the second tube, and an upper portion of the first tube and the second tube by being closed with respect to the housing A state in which the lid portion fixed to the lid portion and the lid portion closed by contacting the lid portion are fixed so as not to be opened, and the lid portion can be opened by releasing the contact with the lid portion A fixing member, a heating plate member for heating and fusing the first tube and the second tube, a heater for heating the heating plate member, and the casing Temperature sensor that measures the temperature of the environment And control for changing the time during which the heating plate member heats the first tube and the second tube by changing the time during which the heater is energized based on the temperature of the environment measured by the temperature sensor. And a portion.

According to the said structure, when fusing and joining a tube, according to the temperature of the environment where the aseptic joining apparatus is put, two tubes can be reliably melted | fused and joined. That is, according to the present inventors, it has been found that the insufficient melting of the tube is caused by the temperature resulting from the heating. For this reason, the present inventors paid attention to the environment in which the apparatus is placed, and proposed to create conditions that require sufficient heating according to the environmental temperature.
That is, according to the present invention, the controller changes the time for energizing the heater based on the environmental temperature measured by the temperature sensor, and the heating plate member heats the first tube and the second tube. You can change the time. For example, when the temperature of the environment is low, the heating plate member prevents the heating of the two tubes from becoming insufficient by changing and lengthening the time for heating the first tube and the second tube. Two tubes can be surely fused and joined. For this reason, the user can perform peritoneal dialysis.

Preferably, the control unit is provided with a threshold for the temperature of the environment measured by the temperature sensor, and the control unit is predetermined when the measured temperature of the environment is higher than the threshold. A predetermined heating time exceeding a predetermined reference heating time when the temperature of the environment is not more than the threshold when the first tube and the second tube are heated by the heating plate member for the reference heating time. Only the first tube and the second tube are heated by the heating plate member.
According to the above configuration, a threshold is set for the environmental temperature, and when the environmental temperature is higher than the threshold, the heating plate member heats the first tube and the second tube for a predetermined reference heating time. . On the other hand, when the environmental temperature is lower than the threshold, the first tube and the second tube are heated by the heating plate member for a predetermined heating time exceeding a predetermined reference heating time. It is possible to lengthen the time for the heating plate member to heat the first tube and the second tube, thereby preventing the two tubes from being insufficiently heated.

Preferably, the control unit changes the state of contact from the state of contact with the lid as the heating time of the first tube and the second tube by the heating plate member increases. The release time of the fixing member until the release is set longer.
According to the above configuration, even when the heating time of the first tube and the second tube by the heating plate member becomes long, the fixing member from the state in which the fixing member is in contact with the lid portion until the contact is released Increase the release time of. For this reason, it is possible to prevent the user from opening the lid portion quickly, and to prevent the user from touching the heat remaining portion of the housing.

Preferably, the fixing member is a lock pin of an electromagnetic solenoid, and the lock pin protrudes from a hole formed in the upper surface of the housing in accordance with a command from the control unit, and is brought into contact with the lid unit. It is characterized by that.
According to the above configuration, the lock pin of the electromagnetic solenoid can be reliably brought into contact with the lid simply by causing the lock pin to protrude from the hole of the housing, and the lid is closed with a simple structure. Can hold.

  The present invention can provide an aseptic joining apparatus that is convenient for a patient. In particular, it is possible to provide an aseptic joining apparatus capable of reliably fusing and joining two tubes when fusing and joining the tubes.

The perspective view which shows embodiment of the aseptic joining apparatus of this invention. 2A is a side view of the aseptic joining apparatus shown in FIG. 1 viewed from the J1 direction, and FIG. 2B is a side view of the aseptic joining apparatus shown in FIG. 1 viewed from the J2 direction. The bottom view of the aseptic joining apparatus shown in FIG. 4A shows an example of an operation panel provided on the front side of the casing shown in FIG. 1, and FIG. 4B shows an example provided on the upper surface of the casing shown in FIG. The figure which shows the example of the display part which is. The figure which shows the example of the two tubes T1 and T2 which the aseptic joining apparatus shown in FIGS. 1-3 is going to join by a hot-melt-pressure joining system. The perspective view which shows the state which opened the clamp cover part shown in FIG. 1 in the RT direction from the housing | casing. The perspective view which shows the internal structure example of the clamp cover part seen from the arrow SS direction in FIG. 6, and the internal structure example of a housing | casing side clamp part. The perspective view seen from another angle which shows the internal structure example of a clamp cover part, and the internal structure example of a housing | casing side clamp part. The perspective view which expands and shows the internal structure of the clamp cover part shown in FIG. 7, and the internal structure of a housing | casing side clamp part. The perspective view which expands and shows the internal structure of the housing | casing side clamp part shown in FIG. 7 from another angle. The perspective view which shows the example of schematic arrangement | positioning of the component arrange | positioned in the housing | casing of an aseptic joining apparatus. The figure which shows the electric block of an aseptic joining apparatus. The perspective view which shows the vicinity of the wafer cassette insertion part of a housing | casing, the wafer cassette taking-out button, and a wafer cassette. The figure which shows a wafer cassette insertion part, a wafer cassette extraction button, and a wafer cassette. The perspective view which shows the bottom face part and upper surface part of a wafer cassette. 16A is a side view of the wafer cassette WC, and FIG. 16B is a plan view of the wafer cassette WC of FIG. The side view which shows the example of the positional relationship of a fan, the two tubes in a housing | casing side clamp part, and a wafer. The figure which shows a mode that the tube T1 and the tube T2 are inserted in the housing | casing side clamp part side. The figure which shows a mode that the previous junction part of tube T2 is pushed in according to the front-end | tip of the protrusion for positioning. The figure which shows the aseptic joining procedure of the two tubes T1 and T2. The flowchart which shows the flow of the operation | work which melts | fuses and joins two tubes using the aseptic joining apparatus 1. FIG.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the drawings.
The embodiments described below are preferred specific examples of the present invention, and thus various technically preferable limitations are given. However, the scope of the present invention is particularly limited in the following description. Unless otherwise stated, the present invention is not limited to these embodiments.
FIG. 1 is a perspective view showing an embodiment of an aseptic joining apparatus of the present invention. 2A is a side view of the aseptic joining apparatus 1 shown in FIG. 1 viewed from the J1 direction, and FIG. 2B is a side view of the aseptic joining apparatus 1 shown in FIG. 1 viewed from the J2 direction. is there. FIG. 3 is a perspective view showing the bottom surface side of the aseptic joining apparatus 1 shown in FIG.
The aseptic joining device 1 shown in FIG. 1 and FIG. 2 heats and melts two tubes for a peritoneal perfusion circuit in an environment of use at an environmental temperature of 10 to 40 ° C. and a relative humidity of 30 to 85%, This is an apparatus for pressure bonding. This aseptic joining apparatus 1 includes, for example, a dialysate tube (hereinafter also referred to as a first tube) of a peritoneal dialysate bag and a tube (hereinafter referred to as a second tube) on a patient's peritoneal catheter side used when performing peritoneal dialysis. Is used for fusing and pressurizing and joining in aseptic conditions.

The aseptic joining apparatus 1 shown in FIG. 1 and FIG. 2 has a size of 135 mm (width) × 99 mm (height) × 268 mm (depth), a weight 2 of 2.4 kg, and a tube setting auxiliary tool 4. have. The housing 2 has a clamp lid 3, and is configured by combining an upper housing portion 2W and a lower housing portion 2V. The housing 2 including the clamp lid 3 and the tube setting auxiliary tool 4 are preferably made of plastic.
The housing 2 accommodates each component described later, and the clamp lid portion 3 is disposed on the upper portion of the housing 2. As will be described later, the tube set auxiliary tool 4 is detachably attached to the housing 2. The housing 2 and the clamp lid 3 are, for example, bright color, cream color, or white, but the user (patient) clearly defines the tube set auxiliary tool 4, the housing 2 and the clamp lid 3 with colors. For example, the tube set auxiliary tool 4 is orange. However, the color of each part is not particularly limited and can be arbitrarily selected.

The housing 2 shown in FIGS. 1 and 2 has a bottom surface portion 2A, a front surface portion 2B, a right side surface portion 2C, a left side surface portion 2D, a back surface portion 2E, and a top surface portion 2F. It is a shape case. As shown in FIG. 3, installation members 2G are respectively attached to the four corner positions of the bottom surface portion 2A. These installation members 2G are, for example, circular anti-slip members made of plastic or rubber. The aseptic joining apparatus 1 having a relatively large weight can be reliably placed by using these installation members 2G so as not to slide with respect to the installation surface, for example, a desk surface. Thereby, the aseptic joining apparatus 1 can be prevented from being displaced, and the work of joining the two tubes by sandwiching and fixing them can be performed.
As shown in FIG. 3, a battery replacement lid 2H is detachably attached to the bottom surface 2A with screws 2I. When the screw 2I is removed and the lid 2H is removed, the battery BA indicated by the broken line inside the housing 2 can be replaced. The lid portion 2H is disposed closer to the back surface portion 2E than the front surface portion 2B, and the lid portion 2H is separated from the exhaust opening 6 of the fan FN.

As shown in FIG. 3, a voice opening 5 and an exhaust opening 6 are formed on the bottom surface 2 </ b> A between the battery replacement lid member 2 </ b> H and the front surface 2 </ b> B. The sound opening 5 is composed of a plurality of elongated through holes 5A, and the exhaust opening 6 has a plurality of elongated through holes 6A arranged in two rows. Inside the bottom surface 2A, a speaker SP and a fan FN as an exhaust device are arranged as indicated by a broken line. The fan FN also serves to cool the wafer WF that has finished the bonding operation.
The voice opening 5 is provided for outputting voice guidance, warning sound, or the like generated by the speaker SP to the outside of the housing 2. Thereby, the user can hear clearly the voice guidance, warning sound, etc. which the speaker SP generate | occur | produces.
The exhaust opening 6 is provided to forcibly exhaust heat generated inside the casing 2 and gas passing through the casing 2 when the cooling fan FN is operated. Yes. Thereby, the heat | fever in the housing | casing 2 or the gas which passes the inside can be discharged | emitted from the bottom face part 2A side to the exterior of the housing | casing 2 instead of the side parts 2C and 2D.
In addition, a plurality of ribs 2J are formed on the bottom surface portion 2A in parallel to the Y direction. These ribs 2J serve as guide portions when a tube setting auxiliary tool 4 to be described later is detachably attached to the housing 2.

Next, the operation panel unit 7 and the display unit 8 will be described with reference to FIG.
FIG. 4A shows an example of the operation panel unit 7 provided on the front surface 2B side of the housing 2 shown in FIG. FIG. 4B shows an example of the display portion 8 provided on the upper surface portion 2F of the housing 2 shown in FIG.
4A includes a [Power] switch button 7B, a [Power] lamp 7C, a [Charging] lamp 7D, a [Join] button 7E, and a [Join] lamp 7F. [Wafer removal] lamp 7G is provided. [Power] lamp 7C, [Charging] lamp 7D, [Joint] lamp 7F, and [Wafer removal] lamp 7G are various display lamps in operation unit 7, for example, a green LED (light emitting diode) lamp. I use it. [Power] switch button 7B is a button that is pressed to turn on the power first when the user tries to join two tubes, which will be described later, using aseptic joining apparatus 1.

[Power] lamp 7C is turned on when [Power] switch button 7B is pressed. The [Join] button 7E is used when the user melts the two tubes to form the end portions of the two tubes, and then replaces the end portions of the two tubes to start pressure bonding. It is a button to be pressed. [Join] lamp 7F is turned on when [Join] button 7E is pressed. In addition, the [Join] lamp 7F may blink to warn the user when a failure occurs. [During charging] The lamp 7D is lit when the battery BA shown in FIG. 3 is charged from the commercial AC power supply side. [Wafer take-out] lamp 7G lights up or blinks when the joining of the two tubes is completed and the user can take out a used wafer, which will be described later, from the housing 2 and discharge it. To do.
In the example of the display unit 8 shown in FIG. 4B, a [close cover] lamp 8B, a [wafer cassette replacement] lamp 8C, a [wafer defect] lamp 8D, a [required charge] lamp 8E, and a [room temperature inappropriate] ] Lamp 8F and [device failure] lamp 8G. [Device failure] The lamp 8G is an important warning lamp for notifying that the device has failed. The red LED lamp is used, but the other lamps are alarm display lamps, for example, a yellow LED lamp. I am using it.

Returning to FIG. 1 and FIG. 2A, the side surface 2 </ b> C of the housing 2 is provided with a wafer cassette insertion portion 20 and a wafer cassette removal button 21. Wafer cassette insertion portion 20 is a rectangular opening for removably inserting wafer cassette WC shown in FIG. In a state where the wafer cassette WC is inserted into the housing 2 through the wafer cassette insertion unit 20, the user presses the wafer cassette eject button 21 with a finger, so that the wafer cassette WC is inserted into the housing 2 through the wafer cassette insertion unit 20. Can be taken out.
As shown in FIG. 2B, a volume adjustment volume 22 and a voice message changeover switch 23 are provided on the side surface 2D of the housing 2. The user can adjust the volume of the voice message according to his / her preference by sliding the volume adjustment volume 22. For example, when the user slides the voice message changeover switch 23 from the “no” state to the “present” state, the voice message can be output from the speaker SP shown in FIG. If the user sets the voice message changeover switch 23 to, for example, a “no” state, for example, a buzzer sound can be output from the speaker SP.

FIG. 5 shows an example of two tubes T1 and T2 to be joined by the aseptic joining apparatus 1 shown in FIGS. The tube T1 is also referred to as a first tube, and the tube T2 is also referred to as a second tube, for example, a tube made of vinyl chloride. However, the material of these tubes is not particularly limited.
In the example shown in FIG. 5, the tube T1 has a connector CT at its distal end, is connected to the dialysate tube TBL of the dialysate bag BL via the branch pipe 9, and is drained from the drain bag HL. The liquid tube THL is connected via a branch pipe 9. The tube T2 includes, for example, an extension tube 10 and a protection tube 11, and the extension tube 10 is connected to a peritoneal catheter 15 via a connecting tube 12, a silicone tube 13, and a catheter joint 14. The peritoneal catheter 15 is inserted into the abdominal cavity of the user M.
As shown in FIG. 5, the aseptic joining apparatus 1 includes a joining part C1 of the tube T1 and a joining part of the tube T2 in a state where the joining part C1 indicated by the oblique line of the tube T1 and the joining part C2 indicated by the oblique line of the tube T2 are stacked. C2 is melted using a heated wafer, which will be described later, so that the melted end of the tube T1 and the melted end of the tube T2 are switched and pressed to join.

Next, the clamp lid part 3 shown in FIG. 1 will be described.
The clamp lid part 3 is provided between the operation panel part 7 and the display part 8 in order to sandwich and hold the two tubes T1 and T2.
FIG. 6 is a perspective view showing a state where the clamp lid 3 shown in FIG. 1 is opened from the housing 2 in the RT direction. FIG. 7 is a perspective view showing an example of the internal structure of the clamp lid part 3 and an example of the internal structure of the housing side clamp part 50 as seen from the direction of the arrow SS in FIG.

As shown in FIGS. 1 and 2, the clamp lid portion 3 includes a clamp plate 30, a clamp operation portion 31, and a covering cover 32. The clamp plate 30 and the covering cover 32 are, for example, cream color or the like so that the user can easily distinguish the clamping operation unit 31 that the user holds with the finger and the clamping plate 30 and the covering cover 32 by visual observation. While it is white, the clamp operation unit 31 is green.
As shown in FIG. 1, a confirmation seal 30 </ b> S is attached to the surface of the clamp plate 30 so that the user can confirm the state of insertion of the two tubes 1 and T <b> 2. Thereby, when the user views the confirmation seal 30 </ b> S, the user can correctly sandwich and join the two tubes 1 and T <b> 2 between the clamp lid portion 3 and the housing-side clamp portion 50.

As shown in FIGS. 1 and 6, the clamp plate 30 is attached to the housing 2 so that it can be opened from the closed state shown in FIG. 1 to the angle exceeding 90 degrees shown in FIG. It is attached to. The covering cover 32 is attached to the housing 2 so as to be rotatable about the central axis CL1. The protrusion 32T of the covering cover 32 is fitted in the guide groove 30R of the clamp plate 30, and the clamp plate 30 is shown in FIG. 6 from the closed state shown in FIG. When the cover cover 32 is opened to an angle exceeding 90 degrees, the covering cover 32 is lifted up following the movement of the clamp plate 30.
The clamp operation part 31 shown in FIGS. 1 and 6 is attached to the tip part 30D of the clamp plate 30 so as to be rotatable around the central axis CL2 using a pin. As shown in FIG. 6, the clamp operation unit 31 has two engagement claws 31M. On the other hand, two protrusions 33 protrude from the housing 2 side. The two protrusions 33 of the clamp operation unit 31 are portions that are fixed by hanging the two engagement claws 31M.

  As shown in FIG. 6, with the clamp lid portion 3 opened from the housing 2, the user holds the clamp operation portion 31 with his finger and rotates about the central axis CL in the direction of the arrow RS. As shown in FIG. 1, the clamp plate 30 can cover the housing side clamp portion 50 from above. Then, as shown in FIG. 1, the user holds the clamp operation unit 31 with his / her finger and rotates it around the central axis CL2 in the direction of the arrow RG, so that the two engaging claws 31M shown in FIG. It is possible to engage with the protruding portion 33 at the position where it is to be engaged. Thereby, the clamp lid part 3 can be reliably fixed mechanically so as not to open during the joining of the two tubes in a state in which the casing side clamp part 50 on the casing 2 side is closed from above. it can.

Next, an example of elements arranged inside the clamp plate 30 and an example of elements arranged inside the casing-side clamp unit 50 will be described with reference to FIGS.
Inside the clamp plate 30, a first tube pressing member 35, a storage member 36, and a storage member 37 are arranged. The first tube pressing member 35, the housing member 36 and the housing member 37 are made of plastic, and a gap 38 is provided between the first tube pressing member 35 and the housing member 36. The housing member 36 has a recess 36A and a recess 36B. Similarly, the housing member 37 has a recess 37A and a recess 37B.

  On the other hand, the housing side clamp part 50 has a first tube sandwiching part 51 and a second tube sandwiching part 52 inside. The first tube sandwiching portion 51 has a first protrusion 51A and a second protrusion 51B. The first protrusion 51A and the second protrusion 51B are arranged to face each other with a sandwiching interval SD shown in FIG. 6 for sandwiching the first tube T1 and the second tube T2 shown in FIG. . Similarly, the second tube sandwiching portion 52 has a first protrusion 52A and a second protrusion 52B. The first protrusion 52A and the second protrusion 52B are arranged to face each other with a sandwiching interval SD shown in FIG. 6 for sandwiching the first tube T1 and the second tube T2 shown in FIG. 5 without being crushed. .

When the clamp lid 3 is closed as shown in FIG. 1, the first protrusion 51 </ b> A and the second protrusion 51 </ b> B of the first tube sandwiching portion 51 shown in FIG. 7 respectively correspond to the corresponding recesses 37 </ b> A and 37 </ b> B shown in FIG. 7. Stored. Similarly, the first protrusion 52A and the second protrusion 52B of the second tube sandwiching portion 52 shown in FIG. 7 are housed in the corresponding recesses 36A and 36B shown in FIG. 7, respectively.
Between the 1st tube clamping part 51 and the 2nd tube clamping part 52, the 2nd tube pressing member 53 is arrange | positioned. The second tube pressing member 53 is in a position corresponding to the first tube pressing member 35 on the clamp plate 30 side. Each of the first tube pressing member 35 and the second tube pressing member 53 has a semi-cylindrical shape. As shown in FIG. 1, when the clamp lid 3 is closed, the second tube pressing member 53 shown in FIG. 7 and the first tube pressing member 35 on the clamp plate 30 side overlap. For this reason, the 1st tube pressing member 35 and the 2nd tube pressing member 53 can comprise the cylindrical member which can accommodate 1st tube T1 and 2nd tube T2. The first tube pressing member 35 and the housing member 37 are integrated members. Similarly, the second tube pressing member 53 and the first tube sandwiching portion 51 are integrated members.

As shown in FIG. 7, for example, a gear 55 is formed around the first tube pressing member 35 and the second tube pressing member 53, and meshes with the gear 56 </ b> G of the clamp motor 56. As a result, when the clamp motor 56 is actuated by a command from the control unit 100 to rotate the gear 56G, the first tube pressing member 35 and the second tube pressing member 53 are integrated with the housing member 37 and the first tube sandwiching portion 51. Thus, the first tube T1 and the second tube T2 after being melted can be kept rotating 180 degrees forward and 180 degrees reverse.
For this reason, the position of the end portion of the first tube T1 after the fusing and the position of the end portion of the second tube T2 can be reversed up and down by 180 degrees. As a result, the melted end of the first tube T1 is located on the upper side after the second tube T2 is located on the upper side and the first tube T1 is located on the lower side before the fusing. The melted end of the second tube T2 can be changed to a lower position.

As shown in FIG. 7, a wafer insertion gap 57 into which the wafer W can be inserted is formed between the second tube pressing member 53 and the second tube sandwiching portion 52.
FIG. 8 is a perspective view showing another example of the internal structure of the clamp lid part 3 and another example of the internal structure of the housing side clamp part 50 as seen from another angle. The housing member 36 of the clamp lid part 3 and the second tube sandwiching part 52 of the housing side clamp part 50 constitute a fixed clamp unit 71 for sandwiching and fixing the two tubes T1 and T2.
With respect to the fixed clamp unit 71, the first tube pressing member 35 and the accommodating member 37 of the clamp lid portion 3, the second tube pressing member 53 of the housing side clamp portion 50, and the first tube sandwiching portion 51 are movable clamp units. 72 is constituted. After the movable clamp unit 72 and the fixed clamp unit 71 are fixed by sandwiching the two tubes T1 and T2, the movable clamp unit 72 has two tubes with respect to the fixed clamp unit 71 which is a fixed portion. It is a movable part for rotating T1 and T2 by 180 degrees.

As shown in FIG. 8, the upper surface portion 2F of the housing 2 has left and right slope portions 2P, 2R. On the inclined surface portion 2P, the side into which the first tube T1 on the dialysate bag side is inserted is indicated by a display label 2X. In the slope portion 2R, the side into which the second tube T2 inside the abdominal cavity is inserted is displayed by a display label 2Y. The second tube T2 on the inner side of the abdominal cavity is disposed so as to overlap the first tube T1.
As shown in FIGS. 6 and 8, a wafer take-out portion 58 for taking out a used wafer WF is provided in the vicinity of the operation panel portion 7 and at an extended position of the gap 57 shown in FIG. ing. By providing the used wafer WF take-out portion 58 on an extension line of the gap 57 through which the wafer WF passes, the user picks up the used wafer WF guided by the wafer take-out portion 58 with a finger. It can be easily taken out.

  As shown in FIG. 8, a circular hole 59 is formed in the vicinity of the take-out portion 58 of the used wafer WF, and a bar-shaped interlock pin 60 is disposed in the hole 59. The interlock pin 60 is a rod of an electromagnetically driven solenoid 61, for example, and the solenoid 61 is raised in the Z1 direction from a state indicated by a broken line to a state indicated by a solid line in response to a command from the control unit 100. Accordingly, the interlock pin 60 holds the front end portion of the clamp operation portion 31 so that the clamp lid portion 3 is not opened while, for example, two tubes are melted and joined. The closed state shown in FIG.

FIG. 9 is an enlarged perspective view showing the internal structure of the clamp lid part 3 and the internal structure of the housing side clamp part 50 shown in FIG. FIG. 10 is a perspective view showing the internal structure of the housing side clamp part 50 in an enlarged manner from another angle.
As shown in FIGS. 9 and 10, a circular hole 74 is formed at the bottom between the first protrusion 52 </ b> A and the second protrusion 52 </ b> B of the second tube sandwiching part 52. The tube detection pin 75 is exposed. When the two tubes T1 and T2 are fitted into the fitting groove 51C between the first protrusion 51A and the second protrusion 51B and the fitting groove 52C between the first protrusion 52A and the second protrusion 52B, this tube detection pin 75 is provided in order to be able to detect that the two tubes T1 and T2 have been fitted correctly, since 75 is pushed down in the direction of the page of FIG. 9 and FIG.

FIG. 11 is a perspective view showing a schematic arrangement example of components arranged in the housing 2 of the aseptic joining apparatus 1.
As shown in FIG. 11, in the housing 2, a main substrate 80, a DC input substrate 81, a wafer cassette storage unit 82, a wafer feed unit 83, a fixed clamp unit 71, a movable clamp unit 72, A solenoid 61, a speaker SP, a fan FN, and a battery BA are accommodated. The DC input board 81 is arranged as far as possible from the main board 80, so that noise from the DC input board 81 does not affect circuit elements mounted on the main board 80. .

FIG. 12 shows an electric block of the aseptic joining apparatus 1.
In the example of the electric block shown in FIG. 12, a CPU such as a microcomputer, a ROM for storing a control program for the entire apparatus executed by the CPU and various data, a RAM for temporarily storing measurement data and various data as a work area, and the like And has a control unit 100 that controls the operation and determination of the entire aseptic joining apparatus 1. The control unit 100 receives power from the battery BA on the DC input board 81 side. The DC input board 81 has a jack 84 and a changeover switch 85. The jack 84 connects a connection pin 86P of the charger 86, thereby allowing a predetermined DC power source obtained by AC / DC conversion from a commercial AC power source. Can receive. The charger 86 and jack 84 are also shown in FIG. The change-over switch 85 in FIG. 12 can connect the jack 84 and the battery BA, and the DC power source from the charger 86 is used for charging the battery BA. The DC power charged in the battery BA is supplied to the control unit 100.
As shown in FIG. 12, a temperature sensor 87 such as a thermistor is electrically connected to the control unit 100, and this temperature sensor 87 detects the ambient temperature (outside air temperature) around the housing 2, and controls the control unit 100. The outside air temperature information TF is supplied to 100. As a result, when the two tubes are heated based on the outside air temperature information TF and the outside air temperature is lower than a predetermined temperature, the control unit 100 lengthens the heating time of the two tubes. There is an advantage that can be processed.
Further, the environmental temperature is notified to the patient by the speaker SP.

As shown in FIG. 12, the [Power switch] button 7B, [Join] button 7E, [Power] lamp 7C, [Charging] lamp 7D and [Join] on the operation panel unit 7 shown in FIG. The lamp 7F and the [wafer removal] lamp 7G are electrically connected to the control unit 100.
The speaker SP shown in FIG. 12 is electrically connected to the control unit 100 via the voice synthesis unit 88, and the speaker SP generates a voice guidance or the like that is determined in advance by a command from the control unit 100. The volume adjustment volume 22 and the voice message changeover switch 23 are electrically connected to the control unit 100. When the voice message selector switch 23 is “present”, voice guidance can be issued from the speaker SP, and when the voice message selector switch 23 is “none”, a buzzer (not shown) can be sounded.
[Close cover] lamp 8B, [Wafer cassette replacement] lamp 8C, [Wafer defective] lamp 8D, [Charge required] lamp 8E, [Inappropriate room temperature] lamp 8F, The apparatus failure] lamp 8G is lit or blinks according to a command from the control unit 100.

  The solenoid 61 of the interlock 60 shown in FIG. 12 is illustrated in FIG. As illustrated in FIG. 8, for example, a photocoupler can be used as the solenoid detection sensor 89, and light 89L from the light emitting unit 89A is received by the light receiving unit 89B. When the interlock 60 of the solenoid 61 is at the lower end position 60L, the light receiving unit 89B prevents the light 89A from the light emitting unit 89A from blocking as shown by a broken line. A signal that the part 3 is not interlocked is supplied. On the other hand, when the interlock 60 of the solenoid 61 is at the upper end position 60H, the interlock 60 does not block the light 89L from the light emitting unit 89A as indicated by the solid line, so that the light receiving unit 89B includes the control unit 100. Is supplied with a “signal that the clamp lid 3 is interlocked”. Thereby, the control part 100 can grasp | ascertain the locked state or non-locking state of the clamp cover part 3. FIG.

The hall sensor 90 of the housing side clamp unit 50 illustrated in FIG. 12 is electrically connected to the control unit 100. As illustrated in FIG. 10, the distal end portion 75A of the tube detection pin 75 is a portion that receives two tubes T1 and T2, and a magnet 91 is attached to the rear end portion 75B of the tube detection pin 75. Between the rear end portion 75B of the tube detection pin 75 and the housing 2, a spring 92 for pushing up the tube detection pin 75 in the Z1 direction is disposed. When the tube T1 and the tube T2 are fitted in the fitting groove 52C between the first projection 52A and the second projection 52B in the order of the tube T1 and the tube T2, the tube T1 and the tube T2 resist the force of the spring 92 in the Z2 direction against the force of the spring 92. Since the tube detection pin 75 is lowered by pushing in, the Hall sensor 90 detects the magnetic force of the magnet 91.
Thereby, the Hall sensor 90 notifies the control unit 100 that “the two tubes T1 and T2 have been properly fitted”. If the tubes T1 and T2 are not sufficiently fitted in the fitting groove 52C, or if only one of the tubes is fitted, the Hall sensor 90 cannot detect the magnetic force of the magnet 91, The hall sensor 90 notifies the control unit 100 that “the two tubes T1 and T2 are not properly fitted”.

As illustrated in FIG. 12, the housing-side clamp unit 50 includes a micro switch 93, and the micro switch 93 is a sensor that detects the closed state of the clamp lid unit 3. As shown in FIG. 1, the micro switch 93 holds the clamp operation part 31 of the clamp lid part 3 with a finger as shown in FIG. 6 and rotates around the central axis CL in the direction of the arrow RS. 30 detects that the housing side clamp part 50 has been closed.
A wafer cassette storage unit 82 shown in FIG. 12 includes a wafer presence / absence sensor 101 and a wafer remaining amount detection sensor 102. The wafer presence / absence sensor 101 is a sensor that detects whether or not the wafer WF remains or remains in the wafer cassette WC shown in FIG. The remaining wafer detection sensor 102 is a sensor that detects how many wafers WF are left in the wafer cassette WC shown in FIG. 1, that is, the remaining number of wafers WF. For example, a photo sensor or the like can be adopted as the wafer presence / absence sensor 101 and the wafer remaining amount detection sensor 102. The wafer WF is an example of a heating plate member for fusing the tubes T1 and T2.

  The wafer feed unit 83 shown in FIG. 12 is a unit for linearly moving the wafer WF in the wafer cassette WC shown in FIG. 1 from the wafer cassette WC to the standby position PS1 shown in FIG. The wafer feed unit 83 shown in FIG. 12 includes a motor 103, a motor drive 104, a forward end sensor 105, an intermediate sensor 106, and a reverse end sensor 107. When the motor drive 102 receives a command from the control unit 100, the motor drive 102 drives the motor 103, so that the wafer WF moves linearly from the wafer cassette WC to the standby position PS1 shown in FIG. The forward end sensor 105, the intermediate sensor 106, and the reverse end sensor 107 detect the forward end position, the intermediate position, and the reverse end position of the wafer WF that moves linearly, and notify the control unit 100 of them.

As shown in FIG. 12, the control unit 100 includes a wafer heater 110, a motor drive 111, a cam motor sensor 112, a clamp motor sensor 113, a micro switch 114, a wafer current detection unit 115, a wafer voltage detection unit 116, and a fan FN. Electrically connected. When the motor drive 111 receives a command from the control unit 100, the motor drive 111 drives the cam motor 117 and the clamp motor 56.
Wafer heater 110 heats the wafer by energization from control unit 100. During this energization, the wafer current detection unit 115 detects the wafer current value supplied to the wafer, and the wafer voltage detection unit 116 detects the wafer voltage value supplied to the wafer.

  The cam motor 117 performs an operation for moving the wafer up and down and an operation for bringing the two tubes together. The operation of moving the wafer up and down by the cam motor 117 is to raise the wafer WF shown in FIG. 7 from the standby position PS1 to the fusing position PS2 above it, and conversely lower the wafer WF from the fusing position PS2 to the standby position PS1. Is the action. Also, the operation of the cam motor 117 to move the two tubes refers to lowering the wafer from the fusing position PS2 to the standby position PS1 and waiting, and then cutting the fusing end of the tube T1 and the fusing end of the tube T2. In this operation, the melted end portion of the counterpart tube T2 and the melted end portion of the counterpart tube T1 are respectively pressed and joined together. The clamp motor 56 performs a 180 degree rotation of the movable clamp unit 72 illustrated in FIG. 7 and a return rotation after the 180 degree rotation. The cam motor sensor 112 is, for example, a photo sensor that detects a cam position and an origin. The clamp motor sensor 113 is, for example, a photo sensor that detects an origin when the movable clamp unit 72 is rotated.

FIG. 13 shows the vicinity of the wafer cassette insertion portion 20 and the wafer cassette takeout button 21 of the housing 2 and the wafer cassette WC. The wafer cassette insertion portion 20 and the wafer cassette takeout button 21 are arranged in the wafer cassette storage unit 82 shown in FIG.
FIG. 14 is a diagram showing the wafer cassette insertion portion 20, the wafer cassette takeout button 21, and the wafer cassette WC. FIG. 15A shows the lower surface of the wafer cassette WC, and FIG. 15B is a perspective view showing the upper surface side of the wafer cassette WC.

  As shown in FIG. 13A, the upper surface 120 of the wafer cassette WC is provided with an arrow 21Y indicating the insertion direction. The user inserts the wafer cassette WC into the wafer cassette insertion portion 20 as shown in FIG. 13B according to the arrow 21Y. After that, when the wafers are used up and there are no more wafers in the wafer cassette WC, the user presses the wafer cassette take-out button 21 with a finger as shown in FIG. 13C, so that the empty wafer cassette WC is removed. It can be taken out from the insertion portion 20.

A structure example of the wafer cassette WC will be described with reference to FIGS. 16A is a side view of the wafer cassette WC, and FIG. 16B is a plan view of the wafer cassette WC of FIG.
Wafer cassette WC is a container for accommodating a plurality of wafers WF, and is preferably made of a transparent plastic so that the internal wafers WF can be visually confirmed. Wafer cassette WC includes upper surface portion 120, bottom surface portion 121, front surface portion 122, side surface portions 123 and 124, and back surface portion 125. As shown in FIG. 16, the front wafer WF (indicated by WF1) is positioned on the inner surface 122N of the front portion 122. As shown in FIG. By pushing the pushing member 126 in the Y1 direction, one wafer WF1 at the tip can be pushed one by one from the inside of the wafer cassette WC along the Y1 direction toward the standby position PS1 shown in FIG. It can be done.

As shown in FIGS. 14 and 15A, two springs 128 and a spring receiving member 129 are accommodated in the wafer cassette WC. One end portions of the two springs are supported by the inner surface 125N of the back surface portion 125, and the other end portions of the two springs are supported by the spring receiving member 129. The spring receiving member 129 is formed with a misalignment prevention unit 130 for preventing the springs 128 from shifting.
Accordingly, the two springs 128 can press the plurality of wafers WC against the inner surface 122N of the front portion 122 via the spring receiving member 129. Therefore, by pressing the pushing member 126 against the leading wafer WF1 in the Y1 direction, only one leading wafer WF can be reliably taken out from the wafer cassette WC along the Y1 direction.
As shown in FIG. 14, the wafer WF is a rectangular metal plate heated by the wafer heater 110 shown in FIG. 12 and has two contact points 131.

Next, the tube setting auxiliary tool 4 will be described with reference to FIGS. 1 to 3.
The tube set auxiliary tool 4 can be attached to the housing 2 as needed by the user. As will be described later, the tube set auxiliary tool 4 reliably performs the work of sandwiching and fixing the two tubes T1 and T2 in the housing side clamp portion 50 as illustrated in FIG. 13C. Act as a guide so you can do it. Accordingly, as shown in FIG. 13C, when the user sandwiches and fixes the two tubes T1 and T2, the user can reliably perform the work without hesitation.

As shown in FIGS. 2 and 3, the tube setting assisting tool 4 has a first side portion 135, a second side portion 136, and a back surface connecting portion 137.
As shown in FIG. 2A, the first side portion 135 has a claw portion 135A and branch portions 135B and 135C. The claw portion 135A meshes with the vicinity of the operation panel portion 7 of the housing 2. As shown in FIG. 2B, the second side portion 136 has a claw portion 136A, branch portions 136B and 136C, and a U-shaped receiving portion 138 for receiving a tube. The claw portion 136 </ b> A is engaged with the vicinity of the operation panel portion 7 of the housing 2. The receiving part 138 receives two tubes T1 and T2 as shown in FIG. As shown in FIG. 2B, by providing a space between the branch portions 136B and 136C, the volume adjustment volume 22 can be exposed, and the user can easily operate the volume adjustment volume 22.

As shown in FIG. 3, the back surface connection part 137 has the 1st connection part 137A and the 2nd connection part 137B. An opening 137C through which the installation member 2G is passed is formed in the first connection portion 137A. The second connecting portion 137B is provided with a protrusion 137D that matches the height of the installation member 2G. Thereby, the housing | casing 2 can be installed in the state which floated only the predetermined space | interval, for example with respect to the desk surface etc. with the four installation members 2G and the two protrusion parts 137D.
Moreover, in order to expose the exhaust opening 5 and the sound opening 6 between the first connecting portion 137A and the second connecting portion 137B, the tube set auxiliary tool 4 includes a fan FN that is an exhaust device. An opening portion 144 that opens the exhaust opening 6 and the sound opening 5 for the speaker SP is formed. Thereby, the fan FN can reliably release the gas and heat inside the housing 2 to the outside of the housing 2 through the opening 6. Also, since the voice guidance, warning sound, etc. generated by the speaker SP can be reliably output to the outside of the housing 2 through the opening 5, it is easy to hear without voice guidance, warning sound, etc.

Next, with reference to FIG. 17, an example of the positional relationship between the fan FN and the two tubes T1, T2 and the wafer WF in the housing side clamp unit 50 will be described. FIG. 17 is a side view schematically illustrating an example of the positional relationship between the fan FN, the two tubes T1 and T2 in the housing-side clamp unit 50, and the wafer WF.
As shown in FIG. 17, the wafer WF in the wafer cassette WC is sent in the Y1 direction from the wafer cassette WC shown in FIG. 17 by operating the wafer feed unit 83 shown in FIG. It can be located at position PS1. When the wafer WF is positioned at the standby position PS1, the two contact points 131 of the wafer WF are connected to the wafer heater 110, and the wafer heater 110 generates heat when energized by a command from the control unit 100. WF is heated.

In the fitting groove 52C between the first protrusion 52A and the second protrusion 52B shown in FIG. 7, two tubes T1 and T2 are stacked and fitted in the Z2 direction, and the position is substantially below the wafer WF that generates heat. Is provided with a fan FN.
When the wafer WF shown in FIG. 17 is raised from the standby position PS1 to the fusing position PS2, and the wafer WF is fusing and joining the two tubes T1 and T2, the gas of the plasticizer is supplied from the two tubes T1 and T2. Occurs.
Even if the plasticizer gas is generated in this way, the plasticizer gas is opened from the exhaust opening 6 of the bottom surface portion 2A as indicated by the discharge path indicated by the thick arrow MY by the rotational drive of the fan FN. It can be reliably discharged to the outside of the body 2. The cam motor 117 shown in FIG. 12 performs an operation for raising the wafer WF from the standby position PS1 to the fusing position PS2 along the Z1 direction, and conversely, an operation for lowering the wafer WF from the fusing position PS2 to the standby position PS1 in the Z2 direction. . Moreover, the cam motor 117 lowers the wafer from the fusing position PS2 to the standby position PS1, and then waits for the fusing end of the tube T1 and the fusing end of the tube T2 to be fused with the fusing end of the other tube T2. An operation is performed in which the melted ends of the opposite tube T1 are pressed and joined together.

Next, the operation of heating and melting the two tubes T1 and T2 shown in FIG. 5 by using the above-described aseptic joining apparatus 1 will be described with reference to FIGS. FIG. 18 is a diagram showing how the tube T1 and the tube T2 are fitted to the housing side clamp portion 50 side, and FIG. 19 shows the joint portion formed by the previous joining of the tube T2 at the tip of the positioning projection 140. It is a figure which shows a mode that it pushes together. FIG. 20 is a diagram showing a procedure of aseptic heating joining of the two tubes T1 and T2.
As shown in FIG. 1, the interlock 60 has already been retracted into the housing 2. When the user grasps the clamp operation part 31 of the aseptic joining apparatus 1 shown in FIG. 1 and lifts it in the direction of the arrow R, the clamp lid part 3 moves away from the case side clamp part 50 as shown in FIG. The clamp part 50 can be opened.

Next, a tube T1 shown in FIG. 18A is prepared, and a joining portion C1 of the tube T1 is a portion to be joined. As shown in FIG. 18B, the tube T1 is fitted in the fitting groove 51C of the first tube sandwiching portion 51 and is fitted in the fitting groove 52C of the second tube sandwiching portion 52 in the X1 direction. In this case, the portion of the tube T1 on the connector CT side is disposed on the U-shaped receiving portion 138 of the tube setting auxiliary tool 4, and the connector CT is positioned outside the receiving portion 138.
In FIG. 18C, the tubes T2 are arranged in the X2 direction in a state where they are stacked on the upper side of the tubes T1. The tube T2 has a joint portion 141 formed at the time of the previous joint, and the cross section of the joint portion 141 is circular.
In FIG. 19A, the tube T2 is fitted in the fitting groove 51C of the first tube sandwiching portion 51 in the X2 direction so that the previous joining portion 141 of the tube T2 is aligned with the tip of the protrusion 140. The second tube sandwiching portion 52 is fitted into the fitting groove 52C. Accordingly, as shown in FIG. 19B, the tube T2 is stacked on the tube T1 along the Z1 direction, and the tubes T1 and T2 are securely fitted in the fitting grooves 51C and 52C in the direction of the arrow RZ. Press to secure.

  Next, the user grasps the clamp operation part 31 shown in FIG. 6, rotates the clamp lid part 3 in the closing direction along the RS direction, and closes the casing-side clamp part 50 by the clamp lid part 3. As a result, as shown in FIG. 20A, the first tube sandwiching portion 51 and the housing member 37 are sandwiched, and the second tube sandwiching portion 52 and the housing member 36 are sandwiched. Moreover, the wafer WF is moved from the wafer cassette WC to the standby position PS1 below the two tubes T1 and T2 having the same thickness as shown in FIG. 20B. For this reason, the wafer WF shown in FIG. 17 is heated to, for example, about 300 ° C. by the heating of the wafer heater 110. The heated wafer WF is raised along the Z1 direction from the standby position PS1 indicated by the broken line to the fusing position PS2 indicated by the solid line, as shown in FIG. 20B, by the operation of the cam motor 117 shown in FIG. Therefore, this wafer WF can melt two tubes T1 and T2 having the same thickness.

Subsequently, as shown in FIG. 20 (C), when the clamp motor 56 shown in FIG. 7 is operated according to a command from the control unit 100, when the clamp motor 56 rotates the gear 56G, the first tube holding member 35 and the second tube. The pressing member 53 is integrated with the housing member 37 and the first tube sandwiching portion 51 and rotates 180 degrees while holding the first tube T1 and the second tube T2. Thereafter, as shown in FIG. 20D, the wafer WF is lowered from the fusing position PS2 to the standby position PS1 along the Z2 direction, and the portions of the tubes T1 and T2 on the side rotated 180 degrees are pushed in the X2 direction. .
As a result, one end of the tube T1 on the side melted by the wafer WF and rotated 180 degrees and one end of the tube T2 are connected to the other end of the tube T2 on the non-rotated side and the other end of the tube T1. Each of the end portions is pressed and joined. Thereafter, when the tubes T1 and T2 are cooled, the aseptic joining is completed.
The used wafer WF is discharged to the used wafer W take-out section 58 as shown in FIG. 1 by the operation of the wafer feeding unit 83 shown in FIG. Thereby, the user can pick up the used wafer WF with a finger and take it out.

After that, when the user grasps the clamp operation unit 31 shown in FIG. 1 again and lifts it in the direction of the arrow RT, the clamp lid 3 is separated from the housing side clamp unit 50 as shown in FIG. The user removes and separates the tubes T1 and T2 after being joined as shown in FIGS. 20E and 20F from the housing-side clamp 50. As described above, as shown in FIG. 20 (F), the tube T1 on the dialysate bag BL side shown in FIG. 5 and the tube T2 on the user M side can be joined aseptically and simply. it can.
As described above, when the wafer WF in the wafer cassette WC shown in FIG. 1 moves in the Y1 direction from the wafer cassette WC as shown in FIG. 17 and is positioned at the standby position PS1 shown in FIG. The two contact points 131 of the WF are connected to the wafer heater 110, and the wafer WF generates heat when the wafer heater 110 generates heat according to a command from the control unit 100.

  As shown in FIG. 10, two tubes T1 and T2 are fitted in the fitting groove 52C between the first protrusion 52A and the second protrusion 52B, and a fan FN is formed below the heat generating wafer WF. Has been placed. When the wafer WF shown in FIG. 17 is raised from the standby position PS1 to the fusing position PS2, and the wafer WF is fusing and joining the two tubes T1 and T2, the gas of the plasticizer is supplied from the two tubes T1 and T2. Will occur. This plasticizer gas can be reliably discharged from the opening 6 of the bottom surface 2A to the outside of the housing 2 by the rotation of the fan FN, as indicated by the thick arrow MY. Since the fan FN and the opening portion 6 for the fan FN are arranged not on the side surface portion of the housing 2 but on the bottom surface portion of the housing 2, the fan FN and the opening portion on the side surface portion of the housing 2 are provided. Thus, the plasticizer gas is not directly ejected to the side. For this reason, even if a plastic product is placed in the vicinity of the casing 2, the plasticizer gas is not directly blown against the plastic product, so that the plastic product is not adversely affected such that a part of the plastic product is melted.

Next, the usage example of the aseptic joining apparatus 1 mentioned above is demonstrated.
FIG. 21 is a flowchart showing the flow of work for fusing and joining two tubes using the aseptic joining apparatus 1.
In step ST1 shown in FIG. 21, as shown in FIG. 9, the two tubes T1 and T2 are inserted into the fitting groove 51C between the first protrusion 51A and the second protrusion 51B, and the first protrusion 52A and the second protrusion 52B. It is fixed by being fitted in the fitting groove 52C. The state where the two tubes T1 and T2 are sandwiched between the fitting groove 51C and the fitting groove 52C is also shown in FIG.
In step ST2 of FIG. 21, as shown in FIG. 17, the tube detection pin 75 is pushed in the Z2 direction by the two tubes T1 and T2, so the Hall sensor 90 detects the magnetic force of the magnet 91, The controller 100 is notified that the two tubes T1 and T2 are correctly fitted and fixed.

In step ST3 of FIG. 21, the user holds the clamp operation part 31 with his / her finger with the clamp lid 3 opened from the housing 2 as shown in FIG. 1, the clamp plate 30 of the clamp lid 3 covers the housing-side clamp 50 from above as shown in FIG. 1. In FIG. 1, the user holds the clamp operation part 31 with his / her finger and rotates it around the center axis CL2 in the direction of the arrow RG, so that the two engaging claws 31M shown in FIG. The protrusion 33 can be engaged with each other. Thereby, the clamp lid part 3 can be reliably fixed mechanically so as not to open during the joining of the two tubes in a state in which the casing side clamp part 50 on the casing 2 side is closed from above. it can.
In step ST4 of FIG. 21, when the two engaging claws 31M of the clamp operation unit 31 are engaged with the protrusions 33 at the corresponding positions, the micro switch 93 is turned on as shown in FIG. To do. When the micro switch 93 is turned on, the closed state of the clamp lid 3 is detected and notified to the control unit 100.

Next, in step ST5 of FIG. 21, when the user depresses the [Join] button 7E, the interlock pin 60 rises in the Z1 direction in step ST6 of FIG. Is mechanically locked. As a result, during the work of fusing the tube and pressurizing and joining, the clamp operation part 31 cannot be operated immediately after this work so that the clamp lid part 3 is not opened carelessly. Thereby, although the part of the housing | casing side clamp part 50 which melts | fuses the tube and pressurizes and joins is high temperature, a user does not touch this high temperature part.
21, the temperature sensor 87 shown in FIG. 12 supplies the outside air temperature information TF to the control unit 100. This outside air temperature information TF is information on the temperature of the environment in which the casing 2 of the aseptic joining apparatus 1 is placed, for example, information on the room temperature of the room in which the casing 2 is placed.

In step ST8 of FIG. 21, when the control unit 100 receives the outside air temperature information TF, the control unit 100 sets the heating time values of the two tubes T1 and T2 by the wafer WF based on the outside air temperature information TF. Set as follows.
The control unit 100 compares the temperature of the outside air temperature information TF with a predetermined threshold temperature TSH. For example, when the temperature TT of the outside air temperature information TF is higher than the predetermined threshold temperature TSH (TT> TSH), in step ST9, the control unit 100 energizes the wafer heater 110 shown in FIG. To do. By energizing the wafer heater 110, the wafer heater 110 heats the wafer WF for a predetermined reference heating time TM1. The threshold temperature TSH and the predetermined reference heating time TM1 are determined as table data stored in advance in the storage unit 100M of the control unit 100. Thereby, the wafer WF is melted by heating the two tubes T1 and T2 for a predetermined reference heating time TM1 (for example, 12 seconds), and the ends of the two melted tubes T1 and T2 are They are replaced with each other and pressurized to be joined.

  Otherwise, when the temperature TT of the outside air temperature information TF is equal to or lower than a predetermined threshold temperature TSH (TT ≦ TSH), in step ST9, the control unit 100 energizes the wafer heater 110 shown in FIG. To do. By energizing the wafer heater 110, the wafer heater 110 heats the wafer WF for an extended heating time TM2 (TM1 <TM2) longer than a predetermined reference heating time TM1. Thereby, the wafer WF was melted by heating the two tubes T1 and T2 for an extended heating time TM2 (for example, 15 seconds) longer than a predetermined reference heating time TM1 (for example, 12 seconds). The ends of the two tubes T1 and T2 are joined to each other by applying pressure to each other.

  Next, in step ST10 of FIG. 21, the control unit 100 sandwiches and fixes the two tubes T1 and T2 that are fused and joined based on the outside temperature information TF that has already been measured and the tubes T1 and T2. In consideration of the time required for heat dissipation of the portion being operated, the interlock pin 60 is retracted in the Z2 direction to release the mechanically locked state of the clamp operation unit 31. That is, in step ST10, the controller 100 sandwiches and fixes the two tubes T1 and T2 that have been joined and the tubes T1 and T2 in accordance with the heating time by the wafer WF described above. Considering the time required for heat dissipation of the clamp part 50, the interlock pin 60 is lowered in the Z2 direction to determine the timing for releasing the lock.

To explain a specific example, when the wafer WF heats the tube for a predetermined reference heating time TM1, the control unit 100 lowers the interlock pin 60 in the Z2 direction to mechanically clamp the clamp lid unit 3. The time for releasing the locked state is set to 20 seconds as, for example, a predetermined reference lock state releasing time TK1.
Alternatively, when the wafer WF heats the tube for an extended heating time TM2 that is longer than a predetermined reference heating time TM1, the control unit 100 sets the time for releasing the lock by lowering the interlock pin 60 in the Z2 direction. For example, the extended lock state release time TK2 longer than a predetermined reference lock state release time TK1 is set to 30 seconds.
As described above, when the tube is heated for a long extended heating time TM2 as compared with the case where the tube is heated with a predetermined reference heating time TM1, the casing-side clamp portion sandwiching and fixing the tubes T1 and T2 is held. Considering the time required for heat dissipation of 50, the longer locked state is held.

In step ST11 of FIG. 21, after the reference lock state release time TK1 predetermined in step ST10 has elapsed, or after the extended lock state release time TK2 has elapsed, the control unit 100 instructs the solenoid 61 to operate the interlock pin 60. Therefore, the user can open the clamp lid 3 by holding the clamp operation part 31 by releasing the mechanical lock state of the clamp operation part 31.
As described above, the unlocking time by the interlock pin 60 is changed according to the length of the heating time by the wafer WF. As a result, while the temperature of the joined portion of the two tubes T1 and T2 and the housing side clamp portion 50 shown in FIG. This prevents the user from touching the remaining heat. Therefore, it is possible to prevent the user from directly touching the joint portion of the two tubes T1 and T2 in a high temperature state and the housing side clamp portion 50 shown in FIG.

  By the way, in order to prevent the interlock pin 60 from popping out of the hole 59 when the aseptic joining apparatus 1 shown in FIG. 1 is transported after manufacture, as shown in FIG. The member 60 </ b> K can be detachably disposed on the operation panel unit 7 of the housing 2. The pop-out preventing member 60K is, for example, a transparent plastic plate and has an L-shaped cross section. The pop-out preventing member 60K can prevent the interlock pin 60 from popping out of the hole 59 due to vibration or the like when, for example, the aseptic joining apparatus 1 is packaged and transported after manufacture. Thereby, after a user opens a package, the situation where the interlock pin 60 jumps out and the clamp cover part 3 cannot be opened can be prevented. And when a user uses the aseptic joining apparatus 1, what is necessary is just to remove this protrusion prevention member 60K from the housing | casing 2. FIG.

  In the aseptic joining apparatus 1 according to the embodiment of the present invention, the housing 2 that fixes the first tube T1 and the second tube T2 and the first tube T1 and the second tube T2 are closed by closing the housing 2. The clamp lid 3 to be fixed and the clamp lid 3 closed by contacting the clamp lid 3 are fixed so as not to be opened, and the clamp lid 3 is opened by releasing the contact with the clamp lid 3. Interlock pin 60 as a fixing member that can be used, wafer WF as a heating plate member for heating and fusing first tube T1 and second tube T2, and heater 110 for heating wafer WF And a temperature sensor 87 that measures the temperature of the environment in which the housing is placed, and the time during which the heater 110 is energized is changed based on the temperature of the environment measured by the temperature sensor 87. And a control unit 100 for changing the time over WF heats the first tube T1 and the second tube T2.

  Thereby, when fusing and joining a tube, according to the temperature of the environment where the aseptic joining apparatus 1 is placed, the two tubes T1 and T2 can be surely melted and joined. That is, the control unit 100 can change the time during which the wafer WF heats the first tube T1 and the second tube T2 by changing the time during which the heater 110 is energized based on the temperature of the environment measured by the temperature sensor 87. . For example, when the temperature of the environment is low, it is possible to prevent the heating of the two tubes from becoming insufficient by increasing the time for the heating plate member to heat the first tube and the second tube. The tube can be surely fused and joined. For this reason, the user can perform peritoneal dialysis.

  The control unit 100 shown in FIG. 12 is provided with a threshold for the temperature of the environment measured by the temperature sensor 87. When the measured temperature of the environment is higher than the threshold, the control unit 100 has a predetermined reference. The first tube T1 and the second tube T2 are heated by the wafer WF for the heating time. When the measured environmental temperature is equal to or lower than the threshold value, the first tube is set by the wafer WF for the predetermined heating time exceeding a predetermined reference heating time. T1 and the second tube T2 are heated. Thereby, when the environmental temperature is higher than the threshold value, the first tube T1 and the second tube T2 are heated by the wafer WF for a predetermined reference heating time. On the other hand, when the environmental temperature is lower than the threshold value, the predetermined temperature is predetermined. The first tube T1 and the second tube T2 are heated by the wafer WF for a predetermined heating time exceeding the reference heating time. For this reason, when the temperature of the environment is equal to or lower than the threshold, that is, for example, in a cold district and the environment temperature is low even in a room, the time for the wafer WF to heat the first tube and the second tube is lengthened. It is possible to prevent the two tubes from being insufficiently heated.

The controller 100 shown in FIG. 12 releases the contact from the state in which the interlock pin 60 contacts the clamp lid 3 as the heating time of the first tube and the second tube by the wafer WF becomes longer. The unlocking time of the interlock pin 60 until it is set is set longer. Thereby, even if the heating time of the first tube and the second tube by the wafer WF becomes longer, the unlocking time of the interlock pin 60 from the state of contact with the clamp lid 3 until the contact is released is lengthened. Therefore, it is possible to prevent the user from inadvertently opening the clamp lid portion 3 inadvertently and touching a portion where heat remains.
The interlock pin 60 of the electromagnetic solenoid 61 protrudes from the hole 59 formed on the upper surface of the housing 2 in accordance with a command from the control unit 100, thereby mechanically contacting the clamp lid 3 and clamping. The lid 3 is brought into a locked state. As a result, the interlock pin 60 can be reliably brought into contact with the clamp lid 3 simply by causing the interlock pin 60 to protrude from the hole 59 of the housing 2. Can hold closed state.

The present invention is not limited to the above embodiment, and various modifications can be made without departing from the scope of the claims.
The aseptic joining device of the present invention is not only used for aseptic joining of two equal-sized tubes for exchanging peritoneal dialysate. The aseptic joining apparatus of the present invention can also be used to automatically join two tubes of the same diameter used for blood transfusion in aseptic conditions, for example, and contaminate bacteria when joining the two tubes. Therefore, the sterility of the blood components in the tube and bag can be maintained.
A part of each configuration of the above embodiment can be omitted, or can be arbitrarily combined so as to be different from the above.

  DESCRIPTION OF SYMBOLS 1 ... Aseptic joining apparatus, 2 ... Housing, 3 ... Clamp lid part, 4 ... Tube set auxiliary tool, 31 ... Clamp operation part, 50 ... Housing side clamp part, 59 ... Housing hole, 60 ... Interlock pin (fixing member), 61 ... Electromagnetic solenoid, 82 ... Wafer cassette storage unit (cassette storage unit), 87 ... Temperature sensor WC ... wafer cassette, WF ... wafer (plate member for heating), T1 ... first tube, T2 ... second tube, TF ... outside air temperature information (environment temperature information), TT: temperature of outside air temperature information, TSH: threshold temperature (threshold of environmental temperature), TK1: predetermined reference lock state release time (release time), TK2: extended lock state release time (Release time)

Claims (4)

Aseptic technique in which the first tube and the second tube are fused while the first tube and the second tube are fixed, and the melted end of the first tube and the melted end of the second tube are replaced and joined. A joining device,
A housing for fixing the first tube and the second tube;
A lid fixed on the first tube and the second tube by being closed with respect to the housing;
A fixing member that fixes the closed lid portion so as not to open by contacting the lid portion, and opens the lid portion by releasing contact with the lid portion; and
A heating plate member for heating and fusing the first tube and the second tube;
A heater for heating the heating plate member;
A temperature sensor for measuring the temperature of the environment in which the housing is placed;
A control unit that changes a time during which the heating plate member heats the first tube and the second tube by changing a time during which the heater is energized based on the temperature of the environment measured by the temperature sensor; An aseptic joining apparatus characterized by comprising:   The control unit is provided with a threshold for the temperature of the environment measured by the temperature sensor, and the control unit performs a predetermined reference heating when the measured temperature of the environment is higher than the threshold. The first tube and the second tube are heated by the heating plate member for a time, and when the measured temperature of the environment is equal to or lower than the threshold, the predetermined heating time exceeding the predetermined reference heating time is used. The aseptic joining apparatus according to claim 1, wherein the first tube and the second tube are heated by a heating plate member.   The control unit releases the contacted state from the state of contact with the lid as the heating time of the first tube and the second tube by the heating plate member becomes longer. The aseptic joining apparatus according to claim 1, wherein a release time of the fixing member is set to be long.   The fixing member is a lock pin of an electromagnetic solenoid, and the lock pin protrudes from a hole formed in the upper surface of the housing according to a command from the control unit, and is brought into contact with the lid unit. The aseptic joining apparatus according to any one of claims 1 to 3.

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