JP5547120B2 - 流路構造体、流体の混合方法、抽出方法及び反応方法 - Google Patents
流路構造体、流体の混合方法、抽出方法及び反応方法 Download PDFInfo
- Publication number
- JP5547120B2 JP5547120B2 JP2011060717A JP2011060717A JP5547120B2 JP 5547120 B2 JP5547120 B2 JP 5547120B2 JP 2011060717 A JP2011060717 A JP 2011060717A JP 2011060717 A JP2011060717 A JP 2011060717A JP 5547120 B2 JP5547120 B2 JP 5547120B2
- Authority
- JP
- Japan
- Prior art keywords
- fluid
- sub
- flow
- substrate
- channel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000012530 fluid Substances 0.000 title claims description 376
- 238000000605 extraction Methods 0.000 title claims description 169
- 238000002156 mixing Methods 0.000 title claims description 64
- 238000000034 method Methods 0.000 title claims description 49
- 238000006243 chemical reaction Methods 0.000 title claims description 37
- 239000000758 substrate Substances 0.000 claims description 130
- 239000000376 reactant Substances 0.000 claims description 100
- 230000002093 peripheral effect Effects 0.000 claims description 5
- 230000000149 penetrating effect Effects 0.000 claims description 2
- 238000011144 upstream manufacturing Methods 0.000 claims description 2
- 239000002609 medium Substances 0.000 description 118
- 238000007789 sealing Methods 0.000 description 38
- 238000011084 recovery Methods 0.000 description 8
- 238000010438 heat treatment Methods 0.000 description 6
- 239000007788 liquid Substances 0.000 description 5
- 230000007423 decrease Effects 0.000 description 3
- 238000005530 etching Methods 0.000 description 3
- 239000002893 slag Substances 0.000 description 3
- 239000007795 chemical reaction product Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000005514 two-phase flow Effects 0.000 description 2
- 238000005452 bending Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 239000002612 dispersion medium Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/24—Stationary reactors without moving elements inside
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/028—Flow sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/30—Injector mixers
- B01F25/31—Injector mixers in conduits or tubes through which the main component flows
- B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
- B01F25/3142—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction
- B01F25/31422—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction with a plurality of perforations in the axial direction only
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
- B01F25/4331—Mixers with bended, curved, coiled, wounded mixing tubes or comprising elements for bending the flow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
- B01F33/81—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
- B01F33/813—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles mixing simultaneously in two or more mixing receptacles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J4/00—Feed or outlet devices; Feed or outlet control devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/716—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00873—Heat exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00889—Mixing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00891—Feeding or evacuation
- B01J2219/00894—More than two inlets
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
- Y10T137/2224—Structure of body of device
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Hydrology & Water Resources (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Extraction Or Liquid Replacement (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Description
次に、本発明の第1実施例として、上記の流路構造体1を用いた抽出方法について説明する。
次に、本発明の第2実施例として、上記の流路構造体1を用いた反応方法について説明する。
2 流通路
4 基板
4a 表面
4b 裏面
12 主流路
14 第1副流路(副流路)
14b 第1副流路導入口(導入口)
16 第1合流部(合流部)
18 第2副流路(副流路)
18b 第2副流路導入口(導入口)
20 第2合流部(合流部)
22 第3副流路(副流路)
22b 第3副流路導入口(導入口)
24 第3合流部(合流部)
Claims (6)
- 第1流体と第2流体が互いに混合するようにそれらの流体を流通させるための流路構造体であって、
前記第1流体と前記第2流体を流通させるための複数の流通路が形成された基板を備え、
前記各流通路は、前記基板の表面に形成され、前記第1流体を当該基板の表面に沿って流すための主流路と、前記基板の前記表面と反対方向を向く面である当該基板の裏面に形成され、前記第2流体を前記基板の前記裏面に沿って流すための複数の副流路と、前記基板をその表面側から裏面側へ当該基板の厚み方向に貫通し、複数の前記副流路に流れる前記第2流体を前記主流路に流れる前記第1流体に合流させるための複数の合流部とを含み、
前記各流通路の前記各副流路は、前記第2流体をその副流路に導入するための導入口をそれぞれ有し、その各導入口は、互いに独立して設けられており、
前記各副流路の前記導入口と反対側の端部は、前記基板の前記表面に垂直な方向から見て、対応する前記主流路の延びる方向に沿って間隔を置いた各位置において当該主流路と重なるように配置され、
前記各合流部は、前記基板のうち前記主流路と前記各副流路の前記端部とが重なる位置に形成されてその主流路とその副流路の端部とを連通し、当該合流部と繋がる前記副流路に流れる前記第2流体の流通方向を前記基板の厚み方向に変化させてその第2流体を前記主流路に流れる前記第1流体に対して合流させ、
前記各流通路の前記主流路は、前記基板の前記表面において並列に配置され、
前記各流通路の複数の前記副流路のうちその流通路の上流側から下流側へ向かって同じ順番に位置する副流路同士は、前記基板の前記裏面において互いに並列に配置されている、流路構造体。 - 前記各副流路の前記導入口は、前記基板の周縁部に配置されている、請求項1に記載の流路構造体。
- 請求項1又は2に記載の流路構造体を用いて第1流体と第2流体とを混合する流体の混合方法であって、
前記基板の前記表面に沿って前記主流路に前記第1流体を流すとともに、その第1流体に前記各副流路及びその各副流路に繋がる前記合流部から前記第2流体をそれぞれ前記基板の厚み方向において合流させて混合する、流体の混合方法。 - 請求項1又は2に記載の流路構造体を用いて抽出対象物を含む被抽出流体とその被抽出流体から前記抽出対象物を抽出するための抽出媒体とを混合し、前記被抽出流体から前記抽出媒体へ前記抽出対象物を抽出させる抽出方法であって、
前記被抽出流体と前記抽出媒体とのうち一方の流体である一流体を前記基板の前記表面に沿って前記主流路に流すとともに、前記被抽出流体と前記抽出媒体とのうち他方の流体である他流体を前記各副流路及びその各副流路に繋がる前記合流部から前記主流路に流れる前記一流体にそれぞれ前記基板の厚み方向において合流させて混合し、
前記両流体の混合流体が前記主流路を下流側へ流れながら、その混合流体中で前記被流出流体から前記抽出媒体へ前記抽出対象物が抽出される、抽出方法。 - 前記一流体は、前記被抽出流体であり、
前記他流体は、前記抽出媒体である、請求項4に記載の抽出方法。 - 請求項1又は2に記載の流路構造体を用いて第1反応剤と第2反応剤とを混合し、それら両反応剤同士を化学反応させる反応方法であって、
前記第1反応剤を前記基板の前記表面に沿って前記主流路に流すとともに、前記第2反応剤を前記各副流路及びその各副流路に繋がる前記合流部から前記主流路に流れる前記第1反応剤にそれぞれ前記基板の厚み方向において合流させて混合し、
前記両反応剤の混合流体が前記主流路を下流側へ流れながら、それら両反応剤が互いに化学反応する、反応方法。
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011060717A JP5547120B2 (ja) | 2011-03-18 | 2011-03-18 | 流路構造体、流体の混合方法、抽出方法及び反応方法 |
US13/363,635 US8986546B2 (en) | 2011-03-18 | 2012-02-01 | Flow channel structure, and mixing method, extraction method, and reaction method for fluids |
EP20120155296 EP2500086B1 (en) | 2011-03-18 | 2012-02-14 | Flow channel structure, and mixing method, extraction method, and reaction method for fluids |
CN201210069949.8A CN102671592B (zh) | 2011-03-18 | 2012-03-16 | 流路构造体、流体的混合方法、提取方法以及反应方法 |
KR1020120027222A KR101369077B1 (ko) | 2011-03-18 | 2012-03-16 | 유로 구조체, 유체의 혼합 방법, 추출 방법 및 반응 방법 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011060717A JP5547120B2 (ja) | 2011-03-18 | 2011-03-18 | 流路構造体、流体の混合方法、抽出方法及び反応方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2012196599A JP2012196599A (ja) | 2012-10-18 |
JP5547120B2 true JP5547120B2 (ja) | 2014-07-09 |
Family
ID=45655696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011060717A Active JP5547120B2 (ja) | 2011-03-18 | 2011-03-18 | 流路構造体、流体の混合方法、抽出方法及び反応方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US8986546B2 (ja) |
EP (1) | EP2500086B1 (ja) |
JP (1) | JP5547120B2 (ja) |
KR (1) | KR101369077B1 (ja) |
CN (1) | CN102671592B (ja) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5642488B2 (ja) | 2010-10-04 | 2014-12-17 | 株式会社神戸製鋼所 | 流路構造体 |
JP5749987B2 (ja) | 2011-06-22 | 2015-07-15 | 株式会社神戸製鋼所 | 液体混合方法及び装置 |
JP6128932B2 (ja) * | 2013-04-22 | 2017-05-17 | 株式会社神戸製鋼所 | 処理装置及び処理方法 |
JP5988504B2 (ja) * | 2013-11-21 | 2016-09-07 | 株式会社神戸製鋼所 | 抽出分離方法 |
JP6036666B2 (ja) * | 2013-11-29 | 2016-11-30 | ブラザー工業株式会社 | 検査チップ |
JP6205317B2 (ja) | 2014-07-14 | 2017-09-27 | 株式会社神戸製鋼所 | 抽出方法 |
JP6190352B2 (ja) * | 2014-12-19 | 2017-08-30 | 株式会社神戸製鋼所 | 流体流通装置及びその運転方法 |
JP6449099B2 (ja) * | 2015-05-25 | 2019-01-09 | 株式会社神戸製鋼所 | 放出処理装置及び放出処理方法 |
JP6912161B2 (ja) * | 2016-02-25 | 2021-07-28 | 株式会社神戸製鋼所 | 流路装置及び液滴形成方法 |
JP6757150B2 (ja) * | 2016-03-17 | 2020-09-16 | 株式会社神戸製鋼所 | 積層型流体加温器及び積層型流体加温器による流体の加温方法 |
JP6342542B1 (ja) * | 2017-04-06 | 2018-06-13 | 株式会社神戸製鋼所 | 流体流路装置 |
GB201804929D0 (en) * | 2018-03-27 | 2018-05-09 | Biome Bioplastics Ltd | Process for oxidising a substrate |
JP7307010B2 (ja) * | 2020-02-28 | 2023-07-11 | トヨタ自動車株式会社 | 冷却器 |
JP2022175476A (ja) * | 2021-05-13 | 2022-11-25 | 株式会社神戸製鋼所 | 流路装置 |
CN115178168B (zh) * | 2022-07-11 | 2024-02-09 | 兖矿鲁南化工有限公司 | 一种羰基化浆态气液混合器及使用方法 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5585069A (en) * | 1994-11-10 | 1996-12-17 | David Sarnoff Research Center, Inc. | Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis |
US6454945B1 (en) * | 1995-06-16 | 2002-09-24 | University Of Washington | Microfabricated devices and methods |
AU6541596A (en) * | 1995-06-16 | 1997-01-15 | University Of Washington | Microfabricated differential extraction device and method |
US6825047B1 (en) * | 1996-04-03 | 2004-11-30 | Applera Corporation | Device and method for multiple analyte detection |
US20020092767A1 (en) * | 1997-09-19 | 2002-07-18 | Aclara Biosciences, Inc. | Multiple array microfluidic device units |
US6136272A (en) * | 1997-09-26 | 2000-10-24 | University Of Washington | Device for rapidly joining and splitting fluid layers |
US20080277007A1 (en) * | 1999-06-28 | 2008-11-13 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
US6454954B1 (en) * | 2000-05-22 | 2002-09-24 | Shipley Company, L.L.C. | Desmear etchant and use thereof |
US6482064B1 (en) * | 2000-08-02 | 2002-11-19 | Interlego Ag | Electronic toy system and an electronic ball |
US6880576B2 (en) * | 2001-06-07 | 2005-04-19 | Nanostream, Inc. | Microfluidic devices for methods development |
US7318912B2 (en) | 2001-06-07 | 2008-01-15 | Nanostream, Inc. | Microfluidic systems and methods for combining discrete fluid volumes |
WO2003015890A1 (en) | 2001-08-20 | 2003-02-27 | President And Fellows Of Harvard College | Fluidic arrays and method of using |
US7691333B2 (en) * | 2001-11-30 | 2010-04-06 | Fluidigm Corporation | Microfluidic device and methods of using same |
CA2480728A1 (en) * | 2002-04-01 | 2003-10-16 | Fluidigm Corporation | Microfluidic particle-analysis systems |
US7718099B2 (en) | 2002-04-25 | 2010-05-18 | Tosoh Corporation | Fine channel device, fine particle producing method and solvent extraction method |
JP4193561B2 (ja) * | 2002-04-25 | 2008-12-10 | 東ソー株式会社 | 微小流路構造体、これを用いた微小粒子製造方法及び微小流路構造体による溶媒抽出方法 |
JP3725109B2 (ja) | 2002-09-19 | 2005-12-07 | 財団法人生産技術研究奨励会 | マイクロ流体デバイス |
WO2004076056A2 (en) * | 2003-02-26 | 2004-09-10 | Lake Shore Cryotronics Inc. | Microfluidic chemical reactor for the manufacture of chemically-produced nanoparticles |
DE10317451A1 (de) | 2003-04-16 | 2004-11-18 | Degussa Ag | Reaktor für heterogen katalysierte Reaktionen |
KR100552706B1 (ko) | 2004-03-12 | 2006-02-20 | 삼성전자주식회사 | 핵산 증폭 방법 및 장치 |
US20050272144A1 (en) * | 2004-06-08 | 2005-12-08 | Konica Minolta Medical & Graphic, Inc. | Micro-reactor for improving efficiency of liquid mixing and reaction |
JP2006075680A (ja) | 2004-09-07 | 2006-03-23 | Shimadzu Corp | 多段階抽出チップ |
JP2006346671A (ja) * | 2005-05-16 | 2006-12-28 | Dainippon Screen Mfg Co Ltd | 液液界面反応装置 |
KR100695151B1 (ko) | 2005-05-18 | 2007-03-14 | 삼성전자주식회사 | 교차 채널을 이용한 유체 혼합 장치 |
TW200733622A (en) * | 2006-01-17 | 2007-09-01 | Interdigital Tech Corp | Method and apparatus for mapping an uplink control channel to a physical channel in a single carrier frequency division multiple access system |
JP4970959B2 (ja) * | 2007-01-09 | 2012-07-11 | 株式会社神戸製鋼所 | 反応装置及び反応方法 |
JP4466682B2 (ja) * | 2007-05-28 | 2010-05-26 | 株式会社日立プラントテクノロジー | 流体混合装置 |
JP4509167B2 (ja) * | 2007-11-05 | 2010-07-21 | ソニー株式会社 | 流路構造、これを備えた流路基板及び流体制御方法 |
US8222049B2 (en) * | 2008-04-25 | 2012-07-17 | Opko Diagnostics, Llc | Flow control in microfluidic systems |
JP4777383B2 (ja) * | 2008-04-28 | 2011-09-21 | 株式会社日立製作所 | マイクロリアクタ |
JP4515521B2 (ja) | 2009-01-13 | 2010-08-04 | 株式会社神戸製鋼所 | 反応装置及び反応装置の製造方法 |
EP2377605B1 (en) | 2009-01-13 | 2015-03-11 | Kabushiki Kaisha Kobe Seiko Sho | Fluid path structure, reactor, and reaction method using the reactor |
US8142741B2 (en) | 2009-01-13 | 2012-03-27 | Kobe Steel, Ltd. | Reactor and method for manufacturing reactor |
JP4515520B2 (ja) | 2009-01-13 | 2010-08-04 | 株式会社神戸製鋼所 | 反応装置及び反応装置の製造方法 |
RU2013114747A (ru) * | 2010-10-18 | 2014-11-27 | Велосис Инк. | Микроканальное технологическое устройство |
-
2011
- 2011-03-18 JP JP2011060717A patent/JP5547120B2/ja active Active
-
2012
- 2012-02-01 US US13/363,635 patent/US8986546B2/en active Active
- 2012-02-14 EP EP20120155296 patent/EP2500086B1/en active Active
- 2012-03-16 CN CN201210069949.8A patent/CN102671592B/zh not_active Expired - Fee Related
- 2012-03-16 KR KR1020120027222A patent/KR101369077B1/ko active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
US20120234755A1 (en) | 2012-09-20 |
KR20120106649A (ko) | 2012-09-26 |
EP2500086A2 (en) | 2012-09-19 |
KR101369077B1 (ko) | 2014-02-28 |
CN102671592B (zh) | 2017-04-26 |
US8986546B2 (en) | 2015-03-24 |
EP2500086A3 (en) | 2013-05-08 |
CN102671592A (zh) | 2012-09-19 |
EP2500086B1 (en) | 2015-04-08 |
JP2012196599A (ja) | 2012-10-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5547120B2 (ja) | 流路構造体、流体の混合方法、抽出方法及び反応方法 | |
JP3088462B2 (ja) | 静的マイクロ混合器 | |
EP1997553B1 (en) | Fluid mixer and method for forming mixed fluid | |
JP4855471B2 (ja) | 積層反応装置 | |
JP6718806B2 (ja) | 流体流通装置 | |
US20140166137A1 (en) | Flow passage structure and flow passage structure manufacturing method | |
CN108495707A (zh) | 空腔x型混合器热交换器 | |
JP2006043617A (ja) | マイクロ流体チップ | |
JP4931065B2 (ja) | 衝突型マイクロミキサー | |
JP5340443B2 (ja) | 多流路機器の運転方法 | |
JP3810778B2 (ja) | 平板静止型混合器 | |
JP2009018311A (ja) | マイクロ流体チップ | |
KR101280642B1 (ko) | 반응 장치 및 반응 장치의 제조 방법 | |
JP5642488B2 (ja) | 流路構造体 | |
JP2006523523A (ja) | 混合装置 | |
JP6046465B2 (ja) | 静止型流体混合装置 | |
JP5885548B2 (ja) | 多流路機器の運転方法及び多流路機器 | |
JP2013103155A (ja) | 流路構造体、分離方法、抽出方法及び反応方法 | |
US20130118588A1 (en) | Fluid treatment method | |
CN116550245A (zh) | 含立体阶梯通道的双层复合微反应通道板、微通道反应器 | |
JP2012120962A (ja) | 流路構造体 | |
JP5808662B2 (ja) | 流体流通装置、抽出方法及び反応方法 | |
CN222490010U (zh) | 一种微反应器 | |
CN221514278U (zh) | 一种错位型三维微混合器 | |
JP4983664B2 (ja) | 冷却装置 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20130822 |
|
A871 | Explanation of circumstances concerning accelerated examination |
Free format text: JAPANESE INTERMEDIATE CODE: A871 Effective date: 20130911 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20131213 |
|
A975 | Report on accelerated examination |
Free format text: JAPANESE INTERMEDIATE CODE: A971005 Effective date: 20131213 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20140107 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140310 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20140430 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20140514 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5547120 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |