JP3976278B1 - Biological monitoring system and program - Google Patents

Abstract

An object of the present invention is to easily grasp a relationship among a blood pressure value, a pulse rate, and an autonomic nerve state.
In the HF-LF / HF display (FIG. 9A), the relationship between the sympathetic nerve activity index (LF / HF) and the parasympathetic nerve activity index (HF) is displayed in a two-dimensional manner. In the pulse rate-blood pressure value display (FIG. 9B), the relationship between the change in the maximum blood pressure value and the change in the pulse rate is two-dimensionally displayed. If the patient's condition is normal, the plots in the two displays move in the same direction. Therefore, the relationship between the pulse rate, the systolic blood pressure, and the state of the autonomic nerve can be easily grasped only by comparing the two displays and confirming that the plots are linked in the same direction.
[Selection] Figure 9

Description

  The present invention relates to a biological monitoring system for monitoring a biological state.

  In recent years, with the increase in the number of elderly people due to longevity and aging, cases of various treatments for patients with diseases such as hypertension and ischemic heart disease are increasing. When such a patient is treated with anesthesia or for a long time, the possibility of an unexpected situation increases.

  Therefore, for example, in dental treatment, when anesthesia is involved, a system for monitoring a patient's biological condition has been developed in order to ensure patient safety (for example, Non-Patent Document 1).

  There has also been proposed a monitoring system that determines whether or not a biological function is functioning normally by observing the state of an autonomic nerve (see, for example, Patent Document 1).

  This patent document 1 discloses a living body monitoring method that detects a change in the activity of the autonomic nerve over time during a medical action or the like, and warns the patient when an abnormal reaction of the patient is predicted, thereby stopping the treatment action. Has been.

  However, in such a conventional biological monitoring system, biological information such as a patient's pulse rate, blood pressure value, and autonomic nerve activity index is only measured and displayed at regular time intervals.

  In the above-mentioned Patent Document 1, the parasympathetic nerve is determined based on the magnitude of the parasympathetic nerve activity index and the sympathetic nerve activity index using a preset formula. It is disclosed to determine whether it is in a dominant state.

  Autonomic nerves include sympathetic nerves that function mainly in an active state and parasympathetic nerves that function mainly in a resting state. In other words, when the sympathetic nerve works predominantly, the living body can be considered to be in an active state, and when the parasympathetic nerve works predominantly, the living body can be considered to be in a resting state.

  Therefore, in general, when the living body is in a resting state, the blood pressure value and the pulse rate are lowered, the autonomic nerve is in a parasympathetic dominant state, and when the living body is in a tension / active state, the blood pressure value and the pulse rate are As a result, the state of the autonomic nerve becomes a sympathetic dominant state.

  However, when the patient's biological function is not working normally, the relationship between the blood pressure value, the pulse rate, and the state of the autonomic nerve may change out of the normal relationship as described above.

  However, in the method disclosed in Patent Document 1, although the relationship between the parasympathetic nerve activity index and the sympathetic nerve activity index is displayed as a graph, the parasympathetic nerve activity index and the sympathetic nerve activity index It is difficult to easily understand how the relationship changes. In particular, in order to grasp the relationship between changes in blood pressure value and pulse rate and changes in the state of the autonomic nerve, determination is performed based on the measurement values of these biological information and a graph created based on the measurement values. There is a need. Therefore, the conventional biological monitoring method cannot easily grasp the relationship between the blood pressure value, the pulse rate, and the state of the autonomic nerve.

JP 2005-261777 A Joe Kaneko et al., Edited by "Monitoring Guide for Measuring, Watching and Reading", Ishiyaku Shuppan Publishing Co., Ltd., October 20, 2004

  The above-described conventional biological monitoring system only displays the measured biological information, and thus has a problem that it is difficult to grasp the relationship between the blood pressure value, the pulse rate, and the state of the autonomic nerve.

  The objective of this invention is providing the biological monitoring system which can grasp | ascertain easily the relationship between a blood-pressure value, a pulse rate, and the state of an autonomic nerve.

[Biological monitoring system]
In order to achieve the above object, the living body monitoring system of the present invention comprises a blood pressure measuring means for measuring a blood pressure value of a living body,
A pulse measuring means for measuring the pulse rate of a living body;
An electrocardiogram measuring means for measuring the electrocardiogram of a living body;
Autonomic nerve activity calculation means for calculating a sympathetic nerve activity index indicating the degree of sympathetic nerve activity and a parasympathetic nerve activity index indicating the degree of activity of the parasympathetic nerve based on the electrocardiographic data measured by the electrocardiogram measurement means When,
Display means for displaying biological information;
A blood pressure value measured before and after the start of treatment measured by the blood pressure measuring means and the pulse rate measuring means, and a change from the reference value of the blood pressure value measured during the treatment by the blood pressure measuring means. A means for calculating a rate and a rate of change from the reference value of the pulse rate measured during treatment by the pulse measuring means, and a relationship between the calculated rate of change of the blood pressure value and the rate of change of the pulse rate in the display means. A control unit configured to display two-dimensionally and display a relationship between the sympathetic nerve activity index and the parasympathetic nerve activity index calculated by the autonomic nerve activity calculating unit with respect to the display unit. Means.

  According to the present invention, since the relationship between the change in blood pressure value and the change in pulse rate and the relationship between the sympathetic nerve activity index and the parasympathetic nerve activity index are respectively displayed, the blood pressure value, the pulse rate, The effect that the relationship of the state of an autonomic nerve can be grasped | ascertained easily can be acquired.

The living body monitoring system of the present invention includes a receiving means for receiving the blood pressure value of the living body measured by the blood pressure measuring means, the pulse rate of the living body measured by the pulse measuring means, and the electrocardiographic data measured by the electrocardiographic measuring means. ,
Autonomic nerve activity calculation means for calculating a sympathetic nerve activity index indicating the activity level of the sympathetic nerve and a parasympathetic nerve activity index indicating the activity level of the parasympathetic nerve based on the electrocardiogram data received by the receiving means;
Display means for displaying biological information;
A blood pressure value measured before and after the start of treatment measured by the blood pressure measuring means and the pulse rate measuring means, and a change from the reference value of the blood pressure value measured during the treatment by the blood pressure measuring means. A means for calculating a rate and a rate of change from the reference value of the pulse rate measured during treatment by the pulse measuring means, and a relationship between the calculated rate of change of the blood pressure value and the rate of change of the pulse rate in the display means. A control unit configured to display two-dimensionally and display a relationship between the sympathetic nerve activity index and the parasympathetic nerve activity index calculated by the autonomic nerve activity calculating unit with respect to the display unit. Means.

[program]
Further, the program of the present invention includes a step in which the blood pressure value and the pulse rate of the living body before the start of treatment measured by the blood pressure measurement unit and the pulse measurement unit are respectively set as reference values ;
Measuring the electrocardiogram of a living body by means of electrocardiogram measuring means;
Based on the electrocardiogram data measured by the electrocardiogram measurement means, calculating a sympathetic nerve activity index indicating the degree of sympathetic nerve activity and a parasympathetic nerve activity index indicating the degree of parasympathetic nerve activity;
Calculating a rate of change from the reference value of the blood pressure value measured during treatment by the blood pressure measuring means and a rate of change from the reference value of the pulse rate measured during treatment by the pulse measuring means;
The relationship between the calculated change rate of the blood pressure value and the change rate of the pulse rate is displayed two-dimensionally on the display means, and the relationship between the calculated sympathetic nerve activity index and the parasympathetic nerve activity index is displayed on the display means. And causing the computer to execute a two-dimensional display step .

  As described above, according to the present invention, the relationship between the change in blood pressure value and the change in pulse rate and the relationship between the sympathetic nerve activity index and the parasympathetic nerve activity index are each displayed in two dimensions. Therefore, it is possible to obtain an effect that the relationship between the blood pressure value, the pulse rate, and the state of the autonomic nerve can be easily grasped.

  Next, embodiments of the present invention will be described in detail with reference to the drawings. FIG. 1 is a block diagram showing a configuration of a living body monitoring system according to an embodiment of the present invention.

  As shown in FIG. 1, the living body monitoring system of the present embodiment measures a manchette (or cuff) 8, a pressure sensor 9, a blood pressure measuring device 12 that measures a blood pressure value of the living body, and a pulse rate of the living body. The pulse measuring device 13, an electrocardiogram monitor 14, a control device 18, a storage device 20, a display device 22 for displaying biological information, and an autonomic nerve activity calculation unit 24 are configured.

  The blood pressure measuring device 12 automatically measures the systolic blood pressure (SYS) and the systolic blood pressure by pressurizing and depressurizing the manchette 8 wound around the upper arm of the living body. The pulse measuring device 13 measures the pulse rate (PR) with the pressure sensor 9 applied to the radial artery of a living body, for example. The pulse can also be measured by using a pulse oximeter instead of the pressure sensor 9.

  The electrocardiogram monitor 14 attaches a minus electrode, for example, to the measurement subject's throat, a plus electrode on the left flank, and a body ground on the right flank, obtains heart movement as an electrical signal and records it as electrocardiographic data.

  The autonomic nerve activity degree calculation unit 24 is based on the electrocardiogram data measured by the electrocardiogram monitor 14 and has a parasympathetic nerve activity index (HF) indicating the degree of parasympathetic nerve activity and the parasympathetic nerve activity degree indicating the degree of sympathetic nerve activity. An index (LF / HF) is calculated. A specific method for calculating LF and LF / HF will be described later.

  The control device 18 includes, for example, a computer, processes the biological information obtained by the blood pressure measuring device 12, the pulse measuring device 13, and the autonomic nerve activity calculating unit 24, and stores the processed information in the storage device 20, or It is displayed on the display device 22. For example, the control device 18 measures the biological information at a constant interval of about 2.5 minutes to 5 minutes and displays it on the display device 22.

  In addition, the control device 18 has reception means for receiving the blood pressure value and pulse rate of the patient measured by the blood pressure measuring device 12 and the pulse measuring device 13, and the blood pressure before the start of treatment by the blood pressure measuring device 12 and the pulse measuring device 13. The value and the pulse rate are measured and stored in the storage device 20 as reference values. Then, the control device 18 calculates the rate of change from the reference value of the blood pressure value measured during treatment by the blood pressure measuring device 12 and the rate of change from the reference value of the pulse rate measured during treatment by the pulse measuring device 13. The calculated relationship between the change rate of the blood pressure value and the change rate of the pulse rate is two-dimensionally displayed on the display device 22.

  Further, the control device 18 two-dimensionally displays the relationship between the sympathetic nerve activity index (LF / HF) calculated by the autonomic nerve activity calculation unit 24 and the parasympathetic nerve activity index (HF) on the display device 22. To do.

  In the display device 22, when the rate of change of the pulse rate and the rate of change of the blood pressure value are two-dimensionally displayed, a dangerous region such as a yellow zone or a red zone in the relationship between the pulse rate and the blood pressure value is displayed. By displaying such a dangerous area, a person who performs treatment can visually determine that the biological state is in a dangerous state.

  Further, the control device 18 may set the dangerous area according to a preset value, or automatically sets the dangerous area according to the patient information input in advance such as the patient's past history, age, and sex. You may make it do.

  Further, the control device 18 does not display the measurement value measured this time on the display device 22, but displays the change from the measurement value previously measured by the blood pressure measurement device 12 and the pulse measurement device 13 on the display device 22. Let's make it.

Next, the operation of the biological monitoring system of this embodiment will be described in detail with reference to FIGS. FIG. 2 is a flowchart showing the operation of the living body monitoring system of this embodiment before treatment, and FIG. 3 is a flowchart showing the operation of the living body monitoring system of this embodiment during treatment.
First, the operation of the biological monitoring system of this embodiment before treatment will be described with reference to FIG.

  Before the treatment is disclosed, patient information such as the patient's name, age, ID number, sex, and past history (diabetes, vascular disorder, etc.) is input to the control device 18 by the person performing the treatment (S101).

  Then, the blood pressure value and the pulse rate during deep breathing are measured by the blood pressure measuring device 12 and the pulse measuring device 13, respectively, and the control device 18 uses the measured blood pressure value and pulse rate as the blood pressure value reference value and the pulse rate reference value, respectively. The value is stored in the storage device 20 (S102).

  The blood pressure value and pulse rate during deep breathing are used as reference values because it is possible to measure a stable value as the value during calmness by measuring the blood pressure value and pulse rate during deep breathing. It is not necessary to take a deep breath as long as the value at the time of calming can be measured.

  Then, the control device 18 sets dangerous areas such as a yellow zone and a red zone based on the input patient information (S103). Here, the control device 18 may simply set ± 20% or more of the reference value as a yellow zone that requires attention and ± 40% or more as a red zone that requires some processing. It is not necessary to make the same setting in the + direction and the − direction. If the blood pressure value during deep breathing is high, the setting is small in the + direction. If the blood pressure value during deep breathing is low, the setting is small in the − direction. You may do it. Further, the control device 18 may automatically set a dangerous area corresponding to each patient according to age, past history, value during deep breathing, and the like.

  And the control apparatus 18 memorize | stores the measured value at the time of the deep breath measured, the setting value of a dangerous area, etc. in the memory | storage device 20, and complete | finishes the process before a treatment (S104).

  Next, the operation of the biological monitoring system of the present embodiment during treatment will be described with reference to FIG.

  During the treatment, the blood pressure value and the pulse rate of the living body are measured by the blood pressure measuring device 12 and the pulse measuring device 13, and the electrocardiographic data is measured by the electrocardiogram monitor 14 (S201). Then, the autonomic nerve activity degree calculation unit 24 performs LF / HF calculation, and performs a sympathetic nerve activity index (LF / HF) indicating the degree of sympathetic nerve activity and a parasympathetic nerve activity index (ie, the degree of parasympathetic nerve activity). HF) is calculated (S202). The measurement results measured by the blood pressure measuring device 12 and the pulse measuring device 13 and the calculation results calculated by the autonomic nerve activity calculating unit 24 are stored in the storage device 20 by the control device 18 and displayed on the display device 22. (S203).

  Then, a timer count for setting a measurement interval is performed (S204), and when a predetermined time has elapsed (S205), the next biological state is measured (S201).

  Then, when such measurement and display are repeated and the safe treatment is completed (S206), the control device 18 ends the process.

  FIG. 3 described above is a flowchart showing the operation of the living body monitoring system of the present embodiment in the case of monitoring the state of the patient during treatment. However, the living body monitoring system of this embodiment can also be used when confirming that the patient's biological functions are working normally by monitoring the state before and after the load is applied to the patient.

  For example, when a standing test is performed from a resting state, the balance of autonomic nerves (balance between sympathetic and parasympathetic nerves) works normally, but if blood pressure does not change, cardio-cerebral vascular ischemia Probability is high and abnormal hemodynamics are predicted. In addition, when the standing test is performed from a resting state, if the autonomic nerve balance does not work normally and the blood pressure does not change, a nerve abnormality is predicted.

  The operation of the living body monitoring system according to the present embodiment in the case where it is determined whether or not the patient's biological function is operating normally by applying some load to the patient will be described with reference to the flowchart of FIG.

  In this case, abdominal breathing is used as an operation to load the patient, and shallow breathing (shallow mouth breathing) is used as an operation not to load the patient. May be any action. For example, an upright test may be used as an operation for applying a load to the patient.

  First, the control device 18 performs abdominal breathing display that prompts the patient to perform abdominal breathing (S301). When this abdominal breathing is completed, measurement of the living body condition (S302), LF / HF calculation (S303), and measurement result display (S304) are performed. The operations in steps S302 to S304 are the same as those in steps S201 to S203 in FIG.

  Then, the control device 18 performs a shallow mouth breath display for prompting the patient to breathe shallowly in the mouth (S305). When this shallow mouth breathing is completed, measurement of the living body condition (S306), LF / HF calculation (S307), and measurement result display (S308) are performed. The operations in steps S306 to S308 are the same as those in steps S201 to S203 in FIG.

  This operation is performed until the determination as to whether the patient's biological function is working normally is completed (S309).

  In this way, it is possible to determine whether or not the patient's biological functions are operating normally by applying a load to the patient and displaying the blood pressure value, pulse rate, and autonomic state before and after that.

  Next, details of the LF / HF calculation method shown in steps S202 of FIG. 3 and steps S303 and S307 of FIG. 4 are shown in FIGS.

  First, in step S <b> 401, the autonomic nerve activity calculation unit 24 calculates heart rate variability from the electrocardiographic data input from the electrocardiogram monitor 14. As shown in FIGS. 6A and B, the heart rate variability was calculated by measuring the RR interval by taking an interval between the R wave and the next R wave, and then measuring as shown in FIGS. 6C and D. The R-R interval data is plotted at the time position of the backward R wave, and after interpolation, data is resampled at equal intervals (dotted line in FIG. 6C). In the next step S402, spectrum analysis (frequency conversion) is performed on the data obtained in step S401. An example of spectrum analysis in step S402 is shown in FIG. In the next step S403, a low frequency component LF is obtained. Here, the low frequency component LF is an integral value of the power spectrum component of 0.04 to 0.15 Hz. In the next step S404, a high frequency component HF is obtained. Here, the high frequency component HF is an integral value of the power spectrum component of 0.15 to 0.40 Hz. In step S405, the ratio obtained in step S403 and the ratio obtained in step S404 are calculated to obtain LF / HF.

  In this way, the autonomic nerve activity calculation unit 24 calculates the parasympathetic nerve activity index (HF) and the sympathetic nerve activity index (LF / HF) from the electrocardiogram data measured by the electrocardiogram monitor 14.

  Next, an example of the display of the display device 22 in the biological monitoring system of the present embodiment is shown in FIG.

  In the display example shown in FIG. 8, the HF-LF / HF display is shown together with the pulse rate, sympathetic activity index (LF / HF), parasympathetic activity index (HF), systolic blood pressure, mean blood pressure, and diastolic blood pressure. 81 and a pulse rate-blood pressure value display 82 are displayed.

  An enlarged view of the HF-LF / HF display 81 and the pulse rate-blood pressure value display 82 shown in FIG. 8 is shown in FIG. FIG. 9A is an enlarged view of the HF-LF / HF display 81, and FIG. 9B is an enlarged view of the pulse rate-blood pressure value display 82. FIG.

  In the display example of the HF-LF / HF display 81 shown in FIG. 9A, the sympathetic nerve activity index (LF / HF) calculated by the autonomic nerve activity calculation unit 24 and the parasympathetic nerve activity index (HF) ) And are displayed two-dimensionally.

  The measured values when HF is the X coordinate and LF / HF is the Y coordinate are plotted and displayed with a circular icon. Here, not only the current measurement value but also the previous measurement value, the previous measurement value, and the previous measurement value are displayed together, and the amount of change between them is indicated by the length of the arrow.

  Assuming from various measurement data, when the sympathetic nerve activity index (LF / HF) is 5.0 abnormal, it is determined that the state of the autonomic nerve is dominant and the parasympathetic nerve activity index ( When HF) is 150 or more, it can be determined that the parasympathetic nerve is dominant. And when the balance function of an autonomic nerve is working normally, when LF / HF becomes large, HF will become small, and when HF becomes large, LF / HF will become small. Therefore, in a normal case, the displayed circular plot should move between the upper right region and the lower left region of the two-dimensional display. In other words, when the displayed circular plot moves to another area, it is presumed that there is some abnormality in the state of the autonomic nerve.

  In the display example of the pulse rate-blood pressure value display 82 shown in FIG. 9B, the rate of change of the blood pressure value and the pulse rate with respect to the reference value during deep breathing is two-dimensionally displayed along with broken lines in increments of ± 10%. A range of ± 20% or more is displayed as a yellow zone, and a range of ± 30% or more is displayed as a red zone danger region. Here, for the convenience of display, the display is performed using the broken lines in increments of ± 10%. However, in order to understand the finer fluctuation, the broken lines in increments of about ± 5% are displayed. Also good.

  Furthermore, the measured values when the pulse rate is the X coordinate and the maximum blood pressure is the Y coordinate are plotted and displayed with a circular icon. Here, not only the current measurement value but also the previous measurement value, the previous measurement value, and the previous measurement value are displayed together, and the amount of change between them is indicated by the length of the arrow. By displaying the past measurement values in this way, the person who performs the treatment can easily grasp how the patient's biological condition is changing.

  On the two-dimensional display screen, if both the pulse rate and systolic blood pressure are high, a message indicating that the state is “tension / pain” is displayed. If both the pulse rate, pulse rate and systolic blood pressure are low, , “Relaxing, cerebral anemia” is displayed. If the pulse rate is high and the systolic blood pressure is low, a message indicating that the state is “shock” is displayed. If the pulse rate is low and the systolic blood pressure is high, a message indicating that the state is “cerebral blood flow disorder”. Has been done.

  In general, the higher the pulse rate, the higher the systolic blood pressure, and the lower the pulse rate, the lower the systolic blood pressure. For this reason, the measured value usually moves on a straight line connecting the “tension / pain” direction and the “relaxation, cerebral anemia” direction. Therefore, when the measurement deviates from the straight line, it is possible to estimate that a serious disorder such as “cerebral blood flow disorder” or “shock state” has occurred in the patient.

  In other words, if the pulse rate fluctuates in a direction lower than the reference value but the systolic blood pressure value fluctuates in a direction higher than the reference value, cerebral blood flow disorder may have occurred. It can be judged.

  If the pulse rate fluctuates higher than the reference value but the systolic blood pressure value fluctuates below the reference value, the patient may be in shock. Judgment can be made.

  In FIG. 9B, the systolic blood pressure measured by the blood pressure measuring device 12 and the rate of change from the reference value of the systolic blood pressure are displayed. The pulse rate measured by the pulse measuring device 13 and the pulse rate The rate of change from the reference value is displayed.

  For example, it is assumed that the maximum blood pressure value and the pulse rate before treatment are 122 mmHg and the pulse rate is 89 bpm. Then, it is assumed that the maximum blood pressure value measured by the blood pressure measuring device 12 is 136 mmHg and the pulse rate measured by the pulse measuring device 13 is 82 bpm at a certain point in time during treatment.

  Then, the blood pressure fluctuation (change rate) is calculated to be + 11% by the following equation.

136mmHg / 122mmHg ≒ 1.114
The pulse fluctuation (rate of change) is calculated to be -8% by the following formula.

82 bpm / 89 bpm ≒ 0.9213
Thus, in the pulse rate-blood pressure value display 82, the relationship between the rate of change between the pulse rate and the blood pressure value is displayed two-dimensionally.

  In the HF-LF / HF display 81, the sympathetic nerve activity index (LF / HF) increases and the parasympathetic nerve activity index (HF) decreases, and in the pulse rate-blood pressure display 82, the pulse The direction in which the number increases and the blood pressure value increases is set to be the same. In the HF-LF / HF display 81, the sympathetic nerve activity index (LF / HF) decreases and the parasympathetic nerve activity index (HF) increases, and the pulse rate-blood pressure value display 82 displays the pulse. The direction in which the number decreases and the blood pressure value decreases is set to be the same.

  Therefore, in the two displays of the HF-LF / HF display 81 and the pulse rate-blood pressure value display 82 shown in FIGS. 9A and 9B, the coordinate axes are devised so that the patient When the state is a resting state, the plot moves to the lower left, and when in the active state or the tension state, the plot moves to the upper right. That is, when the patient's condition is normal, the plot of the HF-LF / HF display 81 and the plot of the pulse rate-blood pressure value display 82 should move in the same direction. Therefore, the person who performs treatment can easily grasp the relationship between the pulse rate, the systolic blood pressure, and the state of the autonomic nerve only by comparing the two displays and confirming that the plots are linked in the same direction. be able to.

  For example, the plot displayed on the HF-LF / HF display 81 is moving normally before and after the test for applying a load to the patient, but the position of the plot displayed on the pulse rate-blood pressure display 82 is changed. If there is no error, it can be easily determined that the probability of cardiac / cerebral vascular ischemia is high.

  As described above, according to the living body monitoring system of the present embodiment, the change in the maximum blood pressure value and the pulse rate are compared with the case where only the maximum blood pressure value, the pulse rate, and the numbers of LF / HF and HF are monitored. Therefore, it is possible to easily grasp the patient's biological state.

[Modification]
In the above embodiment, the pulse rate is measured as the biological information. However, the heart rate of the patient may be measured using a heart rate monitor instead of the pulse meter. In principle, since the heart rate and the pulse rate are the same value, the same effect can be obtained even if the heart rate is used instead of the pulse rate. Furthermore, since the electrocardiogram is measured by the electrocardiogram monitor 14 in the present embodiment, if the heart rate is calculated using this electrocardiogram and used instead of the pulse rate, the pulse meter 13 is used. The present embodiment can be realized.

It is a block diagram which shows the structure of the biological monitoring system of one Embodiment of this invention. It is a flowchart which shows the operation | movement before the treatment of the biological monitoring system of one Embodiment of this invention. It is a flowchart which shows the operation | movement in the treatment of the biological monitoring system of one Embodiment of this invention. It is a flowchart which shows operation | movement of the biological monitoring system of one Embodiment of this invention in the case of determining whether a patient's biological function is working normally by giving a patient some load. It is a flowchart for demonstrating the LF / HF calculation method in the biological monitoring system of one Embodiment of this invention. It is a figure which shows the heart rate fluctuation | variation measuring method in the case of LF / HF calculation. It is a figure which shows an example which spectrum-analyzed in the case of LF / HF calculation. It is a figure which shows an example of the display shown by the display apparatus 22 in FIG. FIG. 9 is an enlarged view of an HF-LF / HF display 81 and a pulse rate-blood pressure value display 82 in FIG. 8.

Explanation of symbols

8 Manchette 9 Pressure sensor 12 Blood pressure measuring device 13 Pulse measuring device 14 ECG monitor 18 Control device 20 Storage device 22 Display device 24 Autonomic nerve activity calculation unit 81 HF-LF / HF display 82 Pulse rate-blood pressure value display S101 to S104 steps S201 to S206 Step S301 to S309 Step S401 to S405 Step

Claims (4)

Blood pressure measuring means for measuring a blood pressure value of a living body;
A pulse measuring means for measuring the pulse rate of a living body;
An electrocardiogram measuring means for measuring the electrocardiogram of a living body;
Autonomic nerve activity calculation means for calculating a sympathetic nerve activity index indicating the degree of sympathetic nerve activity and a parasympathetic nerve activity index indicating the degree of activity of the parasympathetic nerve based on the electrocardiographic data measured by the electrocardiogram measurement means When,
Display means for displaying biological information;
A blood pressure value measured before and after the start of treatment measured by the blood pressure measuring means and the pulse rate measuring means, and a change from the reference value of the blood pressure value measured during the treatment by the blood pressure measuring means. A means for calculating a rate and a rate of change from the reference value of the pulse rate measured during treatment by the pulse measuring means, and a relationship between the calculated rate of change of the blood pressure value and the rate of change of the pulse rate in the display means. A control unit configured to display two-dimensionally and display a relationship between the sympathetic nerve activity index and the parasympathetic nerve activity index calculated by the autonomic nerve activity calculating unit with respect to the display unit. Means,
A biological monitoring system. Receiving means for receiving the blood pressure value of the living body measured by the blood pressure measuring means, the pulse rate of the living body measured by the pulse measuring means, and the electrocardiographic data measured by the electrocardiographic measuring means;
Autonomic nerve activity calculation means for calculating a sympathetic nerve activity index indicating the activity level of the sympathetic nerve and a parasympathetic nerve activity index indicating the activity level of the parasympathetic nerve based on the electrocardiogram data received by the receiving means;
Display means for displaying biological information;
A blood pressure value measured before and after the start of treatment measured by the blood pressure measuring means and the pulse rate measuring means, and a change from the reference value of the blood pressure value measured during the treatment by the blood pressure measuring means. A means for calculating a rate and a rate of change from the reference value of the pulse rate measured during treatment by the pulse measuring means, and a relationship between the calculated rate of change of the blood pressure value and the rate of change of the pulse rate in the display means. A control unit configured to display two-dimensionally and display a relationship between the sympathetic nerve activity index and the parasympathetic nerve activity index calculated by the autonomic nerve activity calculating unit with respect to the display unit. Means,
A biological monitoring system. A step of setting the blood pressure value and the pulse rate of the living body before the start of treatment measured by the blood pressure measuring means and the pulse measuring means as reference values , respectively ;
Measuring the electrocardiogram of a living body by means of electrocardiogram measuring means;
Based on the electrocardiogram data measured by the electrocardiogram measurement means, calculating a sympathetic nerve activity index indicating the degree of sympathetic nerve activity and a parasympathetic nerve activity index indicating the degree of parasympathetic nerve activity;
Calculating a rate of change from the reference value of the blood pressure value measured during treatment by the blood pressure measuring means and a rate of change from the reference value of the pulse rate measured during treatment by the pulse measuring means;
The relationship between the calculated change rate of the blood pressure value and the change rate of the pulse rate is displayed two-dimensionally on the display means, and the relationship between the calculated sympathetic nerve activity index and the parasympathetic nerve activity index is displayed on the display means. A two-dimensional display step,
A program that causes a computer to execute. Receiving a blood pressure value of the living body measured by the blood pressure measuring means, a pulse rate of the living body measured by the pulse measuring means, and electrocardiographic data measured by the electrocardiographic measuring means;
A step of setting the blood pressure value and the pulse rate of the living body before the start of treatment measured by the blood pressure measuring means and the pulse measuring means as reference values, respectively;
Calculating, based on the received electrocardiographic data, the parasympathetic activity indicator of activity the degree of sympathetic activity indicator and the parasympathetic shows the activity degree of sympathetic,
Calculating a rate of change from the reference value of the blood pressure value measured during treatment by the blood pressure measuring means and a rate of change from the reference value of the pulse rate measured during treatment by the pulse measuring means;
The relationship between the calculated change rate of the blood pressure value and the change rate of the pulse rate is displayed two-dimensionally on the display means, and the relationship between the calculated sympathetic nerve activity index and the parasympathetic nerve activity index is displayed on the display means. A two-dimensional display step,
A program that causes a computer to execute.

Images