JP3455789B2 - Film for multi-chamber container and multi-chamber container - Google Patents
Film for multi-chamber container and multi-chamber containerInfo
- Publication number
- JP3455789B2 JP3455789B2 JP04010495A JP4010495A JP3455789B2 JP 3455789 B2 JP3455789 B2 JP 3455789B2 JP 04010495 A JP04010495 A JP 04010495A JP 4010495 A JP4010495 A JP 4010495A JP 3455789 B2 JP3455789 B2 JP 3455789B2
- Authority
- JP
- Japan
- Prior art keywords
- polyethylene
- film
- chamber container
- density polyethylene
- density
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Landscapes
- Package Specialized In Special Use (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Description
【０００１】[0001]
【産業上の利用分野】本発明は複室容器用フィルム、該
フィルムの製造方法及び複室容器に関する。FIELD OF THE INVENTION The present invention relates to a film for a multi-chamber container ,
The present invention relates to a film manufacturing method and a multi-chamber container.
【０００２】[0002]
【従来技術とその問題点】複室容器は同時に配合すると
経時変化を起こすような不安定な各種薬剤（液剤、粉末
剤もしくは固形剤）を個別に収容する複数の室を備え、
各室間を仕切っている容易に剥離開封できる弱シール部
を剥離開封することにより、各室内に収容されている薬
剤を混合できるような構成になっている。2. Description of the Related Art A multi-chamber container is provided with a plurality of chambers for individually accommodating various unstable drugs (liquids, powders or solids) that may change with time when mixed at the same time.
By peeling and opening a weak seal portion that partitions between the chambers and can be easily peeled and opened, the medicines contained in the respective chambers can be mixed.
【０００３】従来、このような複室容器をヒートシール
手段を適用して製造するためのフィルムとして、ポリエ
チレンとポリプロピレンとの混合樹脂からなるフィルム
が知られ、このフィルムはポリエチレンの最低ヒートシ
ール可能温度例えば１２０℃でヒートシールを行うとき
は弱シール部を、またポリプロピレンの最低ヒートシー
ル可能温度例えば１３５〜１４０℃でヒートシールを行
うときは強シール部をそれぞれ形成でき、所謂イージー
ピールシール性を備えている。Conventionally, a film made of a mixed resin of polyethylene and polypropylene is known as a film for producing such a multi-chamber container by applying a heat-sealing means. This film has a minimum heat-sealable temperature of polyethylene. For example, a weak seal portion can be formed when heat sealing is performed at 120 ° C., and a strong seal portion can be formed when heat sealing is performed at the minimum heat sealable temperature of polypropylene, for example, 135 to 140 ° C., and so-called easy peel sealing property is provided. ing.
【０００４】ところがポリエチレンとポリプロピレンと
は、あまり相溶性がよくないので、このような混合樹脂
からフィルムを成形すると、ポリエチレン中でのポリプ
ロピレンの分散が不均一となり、均質なフィルムを成形
することが難しい。However, since polyethylene and polypropylene are not so well compatible with each other, when a film is molded from such a mixed resin, the dispersion of polypropylene in polyethylene becomes uneven, and it is difficult to mold a homogeneous film. .
【０００５】而して、このような不均質なフィルムから
ヒートシール手段を適用して弱シール部と強シール部と
を形成すると、特に弱シール部において、部分的に所定
のシール強度に達しない部分が発生し、この部分が、運
搬時や保管時に落下などによる衝撃を受けた時に自然開
封する恐れがあり、特に、容量の大きい例えば７００〜
１０００ｍｌクラスの複室容器において問題になってい
た。When heat-sealing means is applied from such an inhomogeneous film to form the weak seal portion and the strong seal portion, the predetermined seal strength cannot be partially reached particularly in the weak seal portion. There is a possibility that a portion will be generated, and this portion may be opened naturally when it is shocked by being dropped during transportation or storage.
It was a problem in a multi-chamber container of 1000 ml class.
【０００６】ちなみに、医療分野で通常用いられている
ポリエチレンフィルムを用いるときは、シール強度に殆
どばらつきを生ずることはないが、このようなフィルム
では弱シール及び強シール部を形成するとき、ヒートシ
ール温度としてせいぜい０．５℃程度の温度差しかとれ
ず、金型は通常２℃程度の温度誤差を生ずることを考慮
すると、実質的に弱シール部を形成することはできな
い。By the way, when a polyethylene film which is usually used in the medical field is used, there is almost no variation in the sealing strength, but when such a film is used, a heat seal is formed when a weak seal and a strong seal are formed. Considering that the temperature of the mold is about 0.5 ° C. at most, and the mold usually causes a temperature error of about 2 ° C., the weak seal portion cannot be substantially formed.
【０００７】本発明はこのような従来の問題点を一掃す
ることを目的としてなされたものである。The present invention has been made for the purpose of eliminating such conventional problems.
【０００８】[0008]
【問題点を解決するための手段】本発明は、密度を異に
する少なくとも２種のポリエチレンを含み且つ之等ポリ
エチレン中の最高密度ポリエチレンと最低密度ポリエチ
レンとの間に０．０２ｇ／ｃｍ3 以上の密度差があるポ
リエチレン単一混合物から形成されていることを特徴と
する複室容器用フィルムに係る。The present invention contains at least two kinds of polyethylenes having different densities and has a density of 0.02 g / cm 3 or more between the highest density polyethylene and the lowest density polyethylene in the polyethylene. The present invention relates to a film for a multi-chamber container, which is characterized in that it is formed from a polyethylene single mixture having different density.
【０００９】本発明において、複室容器用フィルムは、
ポリエチレン単一混合物から形成されている。In the present invention, the film for a multi-chamber container is
Formed from a single blend of polyethylene.
【００１０】ポリエチレン単一混合物は密度を異にする
少なくとも２種のポリエチレンを含み、ポリエチレン以
外の樹脂は、これを一切含んでいない。A single polyethylene mixture contains at least two polyethylenes of different densities, and no resins other than polyethylene contain it.
【００１１】上記混合物の単一成分であるポリエチレン
としては、公知の各種のポリエチレン、例えば非晶性ポ
リエチレン、直鎖状低密度ポリエチレン、低密度ポリエ
チレン（高圧法）、高密度ポリエチレンなどをいずれも
使用できる。之等のポリエチレンは、いずれも０．８５
０〜０．９６５ｇ／ｃｍ3 の密度範囲内にあり、この密
度範囲から密度を異にする少なくとも２種を選択すれば
よい。As the polyethylene which is a single component of the above mixture, various known polyethylenes such as amorphous polyethylene, linear low density polyethylene, low density polyethylene (high pressure method), high density polyethylene are used. it can. 0.85 for each of these polyethylenes
It is within a density range of 0 to 0.965 g / cm 3 , and at least two kinds having different densities may be selected from this density range.
【００１２】上記混合物中に含まれる異密度の少なくと
も２種のポリエチレン中、最高密度のポリエチレンと最
低密度のポリエチレンとの間には、０．０２ｇ／ｃｍ3
以上の密度差を有していることが必要である。密度差が
０．０２ｇ／ｃｍ3 に達しない場合には、イージーピー
ルシール性が低下傾向となり、好ましくない。 最高
密度ポリエチレンと最低密度ポリエチレンとの間の密度
差が比較的小さい場合は、これら２成分の混合で充分で
あるが、上記密度差が比較的大きい場合には、成形性を
考慮し之等２成分に加え中間密度のポリエチレンの１種
又はそれ以上を第３成分として混合してもよい。Among at least two kinds of polyethylene having different densities contained in the above mixture, between the highest density polyethylene and the lowest density polyethylene is 0.02 g / cm 3.
It is necessary to have the above density difference. If the density difference does not reach 0.02 g / cm 3 , the easy peel sealing property tends to decrease, which is not preferable. When the density difference between the highest density polyethylene and the lowest density polyethylene is relatively small, mixing these two components is sufficient, but when the density difference is relatively large, moldability should be considered. In addition to the components, one or more intermediate density polyethylenes may be mixed as the third component.
【００１３】上記混合物として異密度２種の混合物を用
いる場合、最低密度ポリエチレンと最高密度ポリエチレ
ンとの混合割合は、重量比で前者：後者＝１〜９：９〜
１、好ましくは、３〜７：７〜３程度が適当であり、混
合割合が之よりはずれると、ヒートシール性が単一のポ
リエチレンフィルムと変わらなくなり、弱シール部の形
成が困難になるので好ましくない。When a mixture of two kinds of different densities is used as the above mixture, the mixing ratio of the lowest density polyethylene and the highest density polyethylene is the former: the latter = 1-9: 9-
1, preferably 3 to 7: 7 to 3 is suitable, and if the mixing ratio is out of proportion, the heat sealability is the same as that of a single polyethylene film, and it is difficult to form a weak seal portion, which is preferable. Absent.
【００１４】上記混合物が第３成分として中間密度のポ
リエチレンを含む場合には、最高密度及び最低密度ポリ
エチレンは、混合物全重量を基準にいずれも１０重量％
以上混合されていることが好ましい。When the mixture contains medium density polyethylene as the third component, the highest and lowest density polyethylenes are both 10% by weight based on the total weight of the mixture.
It is preferable that the above components are mixed.
【００１５】上記混合物において、最低密度ポリエチレ
ンとして、低密度領域例えば密度０．８５０〜０．８８
５ｇ／ｃｍ3（非晶性ポリエチレン ）を用いる場合に
は、成形性などを考慮し、その混合量は、混合物全重量
に対し８０重量％を越えない範囲にとどめるべきであ
る。In the above mixture, the lowest density polyethylene is used as a low density region such as a density of 0.850 to 0.88.
When 5 g / cm 3 (amorphous polyethylene) is used, its mixing amount should be kept within the range of not more than 80% by weight based on the total weight of the mixture in consideration of moldability and the like.
【００１６】またこの場合、他の密度のポリエチレンと
してはできるだけ高密度領域例えば０．９１５ｇ／ｃｍ
3以上、好ましくは０．９２０ｇ／ｃｍ3以上のものを用
いるのがよい。In this case, polyethylene having other densities has a density as high as possible, for example, 0.915 g / cm.
It is preferable to use one having a content of 3 or more, preferably 0.920 g / cm 3 or more.
【００１７】上記のポリエチレン単一混合物を成形原料
として用い、常法に従いフィルムを成形することによ
り、本発明複室容器用フィルムが得られる。The film for a multi-chamber container of the present invention is obtained by forming a film according to a conventional method using the above-mentioned polyethylene single mixture as a forming raw material.
【００１８】上記混合物は、密度を異にする２種又はそ
れ以上のポリエチレンを含んでいるが、密度を異にする
とはいえ相溶性のよいポリエチレン同士の混合物である
ので、密度を異にするポリエチレン同士が互いに均一に
混じりあった、均質なフィルムが得られる。The above-mentioned mixture contains two or more kinds of polyethylene having different densities, but since it is a mixture of polyethylenes having different densities but having good compatibility, polyethylene having different densities is used. A homogeneous film is obtained in which the two are evenly mixed with each other.
【００１９】上記フィルムを構成している、密度の異な
る各種ポリエチレン中、最高密度ポリエチレンは主とし
て強シール部の形成に、また最低密度ポリエチレンは弱
シール部の形成に、それぞれ寄与する。Among various polyethylenes having different densities which compose the film, the highest density polyethylene mainly contributes to the formation of a strong seal portion, and the lowest density polyethylene contributes to the formation of a weak seal portion.
【００２０】強シール部の形成は、最高密度ポリエチレ
ンの最低ヒートシール可能温度を適用して、また弱シー
ル部の形成は、最低密度ポリエチレンの最低ヒートシー
ル可能温度を適用して、それぞれ行うことができる。The strong seal portion can be formed by applying the lowest heat sealable temperature of the highest density polyethylene, and the weak seal portion can be formed by applying the lowest heat sealable temperature of the lowest density polyethylene. it can.
【００２１】本発明では、最高密度ポリエチレンと最低
密度ポリエチレンとの間に、０．０２ｇ／ｃｍ3 以上の
密度差を設けているので、この密度差を最低ヒートシー
ル可能温度の温度差に置き換えると、少なくとも５℃程
度の温度差となる。In the present invention, since a density difference of 0.02 g / cm 3 or more is provided between the highest density polyethylene and the lowest density polyethylene, if this density difference is replaced with the temperature difference of the lowest heat sealable temperature. The temperature difference is at least about 5 ° C.
【００２２】例えば最高密度ポリエチレンを０．９４０
〜０．９６５ｇ／ｃｍ3 に選択し、最低密度を０．９０
５〜０．９４０ｇ／ｃｍ3 に選択するときは、強シー
ル部を１４５〜２００℃、また弱シール部を１１５〜１
４５℃の温度条件で形成することができる。For example, the highest density polyethylene is 0.940.
~ 0.965g / cm 3 selected, minimum density 0.90
When selecting 5 to 0.940 g / cm 3 , the strong seal portion is 145 to 200 ° C., and the weak seal portion is 115 to 1
It can be formed under a temperature condition of 45 ° C.
【００２３】このように強シール部の形成温度と弱シー
ル部の形成温度の間に、充分な温度差をとることができ
るので、弱シール部の形成を容易に安定確実におこなう
ことができる。Since a sufficient temperature difference can be obtained between the formation temperature of the strong seal portion and the formation temperature of the weak seal portion in this way, the formation of the weak seal portion can be performed easily and reliably.
【００２４】またこのようにして形成されたシール部に
おいては、先に述べたように、最高密度ポリエチレンと
最低密度ポリエチレンが均一分散状態に混じり合ってい
るため、シール強度にむらを生ずることがなく、強シー
ル部並びに弱シール部を設定通りのシール強度の持つよ
うに形成することが可能になる。Further, in the seal portion thus formed, as described above, since the highest density polyethylene and the lowest density polyethylene are mixed in a uniformly dispersed state, there is no unevenness in the seal strength. It is possible to form the strong seal portion and the weak seal portion so as to have the seal strength as set.
【００２５】本発明フィルムはこのようにイージーピー
ルシール性を備えているので、従来のフィルムと同様に
ヒートシール手段を適用することにより容易に複室容器
を成形できる。Since the film of the present invention has such an easy peel sealing property, the multi-chamber container can be easily formed by applying the heat sealing means as in the conventional film.
【００２６】本発明フィルムを用いて複室容器を成形す
る場合、単層フィルムの状態で用いる場合と、他のフィ
ルムと組合わせた多層フィルムの状態で用いられる場合
とがあり、後者の場合、本発明フィルムは多層フィルム
の最内層を構成している。When a multi-chamber container is formed using the film of the present invention, it may be used in the state of a single layer film or in the state of a multilayer film in combination with another film. In the latter case, The film of the present invention constitutes the innermost layer of the multilayer film.
【００２７】[0027]
【発明の効果】本発明によれば、最高密度ポリエチレン
と最低密度ポリエチレンとが均一に混じり合った均質な
イージーピールシール性フィルムを提供でき、該フィル
ムを用いることにより、弱シール部の自然開封の恐れの
ない複室容器が得られる。以下に本発明の実施例及び試
験例を掲げる。According to the present invention, it is possible to provide a homogeneous easy peel seal film in which the highest density polyethylene and the lowest density polyethylene are uniformly mixed, and by using the film, the weak seal portion can be naturally opened. A fearless multi-chamber container is obtained. Examples and test examples of the present invention will be listed below.
【００２８】[0028]
実施例１
直鎖状低密度ポリエチレン〔商品名：ウルトゼックス、
三井石油化学工業（株）製、密度：０．９４０ｇ／ｃｍ
3 、ＭＩ＝２（１９０℃）〕（以下、Ｌ−ＬＤＰＥと
する）と高密度ポリエチレン〔商品名：ネオゼックス、
三井石油化学工業（株）製、密度：０．９６５ｇ／ｃｍ
3 、ＭＩ＝１５（１９０℃）〕（以下、ＨＤＰＥとす
る）を重量比５：５で混合し、成形温度１３０〜１５０
℃でＴダイ法にて幅２４０ｍｍ、厚さ１８４μｍの単層
フィルムを製造した。このフィルムを引き取り方向に各
々約５５０ｍｍの長さにカットした。このフィルムを二
つ折りにし、シール幅１０ｍｍとなるように折った部分
を含めた三箇所を上下の金型の温度条件約１７０℃でヒ
ートシールした。これによって、三方向が溶着した外寸
横方向１００ｍｍ、縦方向２５０ｍｍの袋（バッグ）を
作製した。そして、開口部分に密度：０．９４５ｇ／ｃ
ｍ3 のポリエチレン で作製したポート部を熱溶着する
と共に、バッグの開口部をヒートシールした。 このバッ
グのポート部溶着基部より１００ｍｍの部分に、バッグ
を二分するように幅１０ｍｍの弱シール部（以下、ＥＰ
Ｓ，温度条件約１４０℃）を設け目標とする複室容器を
成形した。Example 1 Linear low-density polyethylene [trade name: Ultozex,
Mitsui Petrochemical Industry Co., Ltd., density: 0.940 g / cm
3 , MI = 2 (190 ° C.)] (hereinafter referred to as L-LDPE) and high density polyethylene [trade name: Neozex,
Mitsui Petrochemical Industry Co., Ltd., density: 0.965 g / cm
3 , MI = 15 (190 ° C.)] (hereinafter referred to as HDPE) at a weight ratio of 5: 5, and the molding temperature is 130 to 150.
A monolayer film having a width of 240 mm and a thickness of 184 μm was manufactured by a T-die method at a temperature of ℃. The film was cut into a length of about 550 mm in the take-up direction. This film was folded in two and heat-sealed at three locations including the folded portion so that the seal width was 10 mm under the temperature conditions of the upper and lower molds of about 170 ° C. As a result, a bag having an outer dimension of 100 mm in the lateral direction and 250 mm in the longitudinal direction, which was welded in three directions, was produced. And the density at the opening is 0.945 g / c
The port made of m 3 polyethylene was heat-welded and the opening of the bag was heat-sealed. This bag has a weak seal part (hereinafter referred to as EP) with a width of 10 mm that divides the bag into 100 mm from the welded base of the port part.
S, a temperature condition of about 140 ° C.) was provided to form a target multi-chamber container.
【００２９】実施例２
Ｌ−ＬＤＰＥとＨＤＰＥを重量比５：５で混合した
混合樹脂からなる層３０μｍを内層に有し、Ｌ−ＬＤＰ
Ｅと非晶性ポリエチレン〔商品名：タフマーＡ、三井
石油化学工業（株）製、密度：０．８８５ｇ／ｃｍ3、
ＭＩ＝０．５（１９０℃）〕を重量比３：７で混合した
混合樹脂からなる層１１５μｍを中間層に有し、Ｌ−Ｌ
ＤＰＥからなる層３０μｍを外層に有する三層フィル
ムを成形温度１３０〜１６０℃で共押出Ｔダイ法にて製
造した。Example 2 L-LDP has an inner layer of 30 μm made of a mixed resin in which L-LDPE and HDPE are mixed at a weight ratio of 5: 5.
E and amorphous polyethylene [trade name: Toughmer A, manufactured by Mitsui Petrochemical Industry Co., Ltd., density: 0.885 g / cm 3 ,
MI = 0.5 (190 ° C.)] in a weight ratio of 3: 7 and having a layer 115 μm made of a mixed resin as an intermediate layer.
A three-layer film having a DPE layer of 30 μm as an outer layer was produced at a molding temperature of 130 to 160 ° C. by a coextrusion T-die method.
【００３０】また、実施例１と同様の方法により幅２４
０ｍｍのフィルムを製造しこのフィルムを用い、実施例
１と同様の操作で複室容器を成形した。Further, the width 24 is obtained by the same method as in the first embodiment.
A 0 mm film was produced, and a multi-chamber container was molded by the same operation as in Example 1 using this film.
【００３１】[0031]
【試験例】実施例１及び２で成形した複室容器を用いて
以下の実験を行った。まず、複室容器のポート部より注
射用水１００ｍｌを充填し、日本薬局方（第１２改正）
に合格したゴム栓を嵌め込んだポリエチレン製キャップ
（密度：０．９４５ｇ／ｃｍ3 ）をポート部に熱溶着し
た。この複室容器を高圧蒸気滅菌後ポート部を有しない
側の室を開封し、セファゾリンナトリウム１ｇ力価相当
を無菌充填した。充填後ヒートシール手段によって再度
密封した複室容器を２４時間室温に放置して、以下の実
験１、２に供し、成形した複室容器の適格性を判定し
た。その結果、本条件で成形したＥＰＳ付き複室容器の
性能が十分実用に耐えられる性能を有しているのが明ら
かとなった。[Test Example] The following experiment was conducted using the multi-chamber container molded in Examples 1 and 2. First, fill 100 ml of water for injection from the port of the multi-chamber container, and then take the Japanese Pharmacopoeia (12th revision).
A polyethylene cap (density: 0.945 g / cm 3 ) fitted with a rubber plug that passed the above criteria was heat-welded to the port. This multi-chamber container was sterilized by high-pressure steam, and then the chamber on the side having no port was opened and aseptically filled with 1 g of cefazolin sodium titer. The multi-chamber container, which was resealed by the heat-sealing means after the filling, was left at room temperature for 24 hours and subjected to the following Experiments 1 and 2 to determine the suitability of the molded multi-chamber container. As a result, it became clear that the performance of the EPS-equipped multi-chamber container molded under these conditions was sufficiently high enough for practical use.
【００３２】実験１「加圧試験」
上記のようにして製造した複室容器を注射用水を充填し
た部分が上になるようにＥＰＳ部分で二つ折りにし、東
洋精機製作所製ＳＴＲＯＧＲＡＰＨ−Ｍ２試験機（加圧
モード、１００ｋｇ加圧）のワーク受け台中央に置い
た。そして、ヘッド下降スピード５０ｍ／ｍｉｎで複室
容器を加圧（加圧保持５秒）し、複室容器のシール部分
等の破損を調べた。Experiment 1 "Pressurization test" The multi-chamber container manufactured as described above was folded in two at the EPS part so that the part filled with water for injection was on the top, and a STROGRAPH-M2 tester manufactured by Toyo Seiki Seisakusho ( It was placed in the center of the work cradle in the pressure mode, 100 kg pressure). Then, the multi-chamber container was pressed at a head descending speed of 50 m / min (pressurizing and holding for 5 seconds), and damage to the seal portion of the multi-chamber container was examined.
【００３３】なお、複室容器をＥＰＳ部分で二つ折りす
るのは、ＥＰＳ部分が１００ｋｇの加圧によっても開封
しないようにするためである。The multi-chamber container is folded in two at the EPS portion so that the EPS portion will not be opened even when a pressure of 100 kg is applied.
【００３４】その結果を表１にしめす。The results are shown in Table 1.
【００３５】[0035]
【表１】 [Table 1]
【００３６】実験１の結果により強シール部が充分なシ
ール強度を有していることが判る。From the results of Experiment 1, it can be seen that the strong seal portion has sufficient seal strength.
【００３７】[0037]
【実験２】「ＥＰＳ開通試験」
実験１に供した二つ折りとなった試験検体（複室容器）
を広げ、液部を実験１と同じ試験機のワーク受け台中央
に置き、ヘッド下降スピード５０ｍ／ｍｉｎで、液部を
加圧させＥＰＳの開通時の圧力値を記録紙より読みとる
と共に、複室容器並びにＥＰＳを含めたシール部の異常
有無を目視確認した。その結果を表２に示す。尚、表２
に記載のＳＤは標準偏差を示す。[Experiment 2] "EPS Opening Test" The test specimen folded in two (multi-chamber container) used in Experiment 1
Spread the liquid part, place the liquid part in the center of the work cradle of the same tester as in Experiment 1, press the liquid part at a head descending speed of 50 m / min, read the pressure value at the time of EPS opening, from the recording paper, and double chamber. The presence or absence of abnormality in the seal part including the container and EPS was visually confirmed. The results are shown in Table 2. Table 2
SD described in (1) indicates standard deviation.
【００３８】[0038]
【表２】 [Table 2]
【００３９】実験２の結果によりＥＰＳ部にシール強度
のばらつきがほとんどないことが判る。From the results of Experiment 2, it can be seen that there is almost no variation in seal strength in the EPS part.
───────────────────────────────────────────────────── フロントページの続き (56)参考文献 特開 平６−246886（ＪＰ，Ａ) 特開 平５−193160（ＪＰ，Ａ) 特開 平６−142160（ＪＰ，Ａ) 特開 平２−4671（ＪＰ，Ａ) 特開 平５−49673（ＪＰ，Ａ) 特開 平４−266759（ＪＰ，Ａ) 特開 平６−209981（ＪＰ，Ａ) 特開 平６−47878（ＪＰ，Ａ) 特開 平６−14975（ＪＰ，Ａ) 特開 平４−40956（ＪＰ，Ａ) (58)調査した分野(Int.Cl.7，ＤＢ名) A61J 1/05 B65D 81/32 ─────────────────────────────────────────────────── ─── Continuation of the front page (56) Reference JP-A-6-246886 (JP, A) JP-A-5-193160 (JP, A) JP-A-6-142160 (JP, A) JP-A-2- 4671 (JP, A) JP 5-49673 (JP, A) JP 4-266759 (JP, A) JP 6-209981 (JP, A) JP 6-47878 (JP, A) JP-A-6-14975 (JP, A) JP-A-4-40956 (JP, A) (58) Fields investigated (Int.Cl. 7 , DB name) A61J 1/05 B65D 81/32
Claims (6)
チレンを含み且つ之等ポリエチレン中の最高密度ポリエ
チレンと最低密度ポリエチレンとの間に０．０２ｇ／ｃ
ｍ3 以上の密度差があるポリエチレン単一混合物から形
成されていることを特徴とする弱シール部形成機能を伴
った複室容器用フィルム。1. 0.02 g / c between at least two polyethylenes of different densities and between the highest density polyethylene and the lowest density polyethylene in the equal polyethylene.
With a weak seal forming function, characterized in that it is formed from a polyethylene single mixture having a density difference of m 3 or more.
Multi-chamber container for the film Tsu.
チレンと最低密度ポリエチレンとの２種混合物であり、
且つ前者対後者の混合割合が重量比で１〜９対９〜１で
ある請求項１記載の複室容器用フィルム。2. A polyethylene single mixture is a mixture of two types of highest density polyethylene and lowest density polyethylene,
The film for a multi-chamber container according to claim 1, wherein the mixing ratio of the former to the latter is 1 to 9: 9 to 1 by weight.
エチレンと、最低密度ポリエチレンと、中間密度ポリエ
チレンの少なくとも１種との混合物であり、該混合物
は、最高密度ポリエチレンと最低密度ポリエチレンと
を、混合物全重量に対し、それぞれ１０重量％以上、含
んでいることを特徴とする請求項１記載の複室容器用フ
ィルム。3. A single polyethylene mixture is a mixture of highest density polyethylene, lowest density polyethylene and at least one of medium density polyethylene, the mixture comprising highest density polyethylene and lowest density polyethylene. The film for a multi-chamber container according to claim 1, wherein the film contains 10% by weight or more, respectively, relative to the weight.
９６５ｇ／ｃｍ3 の密度範囲から選択されていることを
特徴とする請求項１〜３のいずれか１つに記載の複室容
器用フィルム。4. The density of polyethylene is 0.850 to 0.
The film for a multi-chamber container according to any one of claims 1 to 3, which is selected from a density range of 965 g / cm 3 .
からヒートシール手段を適用して成形された複室容器。5. A multi-chamber container molded by applying heat-sealing means from the film according to claim 1.
レンを含み且つ之等ポリエチレン中の最高密度ポリエチ
レンと最低密度ポリエチレンとの間に０．０２ｇ／ｃｍ
3 以上の密度差があるポリエチレン単一混合物を、成形
原料として用いることを特徴とする弱シール部形成機能
を伴った複室容器用フィルムの製造方法。 6. At least two kinds of polyethylene having different densities.
Highest density polyethylene containing polyethylene
0.02g / cm between Ren and the lowest density polyethylene
Mold polyethylene single mixture, with density difference of 3 or more
Weak seal part formation function characterized by being used as a raw material
And a method for producing a film for a multi-chamber container.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP04010495A JP3455789B2 (en) | 1995-02-28 | 1995-02-28 | Film for multi-chamber container and multi-chamber container |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP04010495A JP3455789B2 (en) | 1995-02-28 | 1995-02-28 | Film for multi-chamber container and multi-chamber container |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH08229101A JPH08229101A (en) | 1996-09-10 |
| JP3455789B2 true JP3455789B2 (en) | 2003-10-14 |
Family
ID=12571561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP04010495A Expired - Lifetime JP3455789B2 (en) | 1995-02-28 | 1995-02-28 | Film for multi-chamber container and multi-chamber container |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3455789B2 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19835346A1 (en) | 1998-08-05 | 2000-02-10 | Boehringer Ingelheim Pharma | Two-part capsule for pharmaceutical preparations for powder inhalers |
| EP1080711B1 (en) | 1999-03-02 | 2008-06-18 | Hosokawa Yoko Co., Ltd. | Multi-chamber medical container |
| WO2004080370A1 (en) | 2003-03-12 | 2004-09-23 | Fujimori Kogyo Co., Ltd. | Multiple compartment container |
| JP4644480B2 (en) * | 2004-07-13 | 2011-03-02 | ベスパック株式会社 | Polyolefin resin multi-chamber bag |
| DE102005001332A1 (en) | 2005-01-11 | 2006-07-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Two-piece capsule with pre-closure for holding pharmaceutical preparations for powder inhalers |
| US9004761B2 (en) | 2006-05-01 | 2015-04-14 | Baxter International Inc. | Multiple chamber container with mistake proof administration system |
| WO2012026520A1 (en) * | 2010-08-27 | 2012-03-01 | 株式会社細川洋行 | Medical drug solution container |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2675075B2 (en) * | 1988-06-10 | 1997-11-12 | 株式会社新素材総合研究所 | Container with contents |
| JP3054426B2 (en) * | 1990-06-06 | 2000-06-19 | 昭和電工株式会社 | Medical bag |
| JP3052398B2 (en) * | 1991-02-21 | 2000-06-12 | 昭和電工株式会社 | Medical bag |
| JPH0549673A (en) * | 1991-08-23 | 1993-03-02 | Terumo Corp | Container for liquid drug |
| JPH05193160A (en) * | 1992-01-20 | 1993-08-03 | Seiko Epson Corp | Impact dot head |
| JP3079403B2 (en) * | 1992-05-03 | 2000-08-21 | 株式会社大塚製薬工場 | Double chamber container |
| JP3250016B2 (en) * | 1992-05-29 | 2002-01-28 | キョーラク株式会社 | Blow container for chemical solution |
| JPH0647878A (en) * | 1992-07-31 | 1994-02-22 | Tonen Chem Corp | Easy peel multilayered film for polyethylenic packing material |
| JP3091069B2 (en) * | 1992-12-28 | 2000-09-25 | 三井化学株式会社 | Resin laminate and its use |
| JPH06209981A (en) * | 1993-01-19 | 1994-08-02 | Terumo Corp | Basic member for medical container |
-
1995
- 1995-02-28 JP JP04010495A patent/JP3455789B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08229101A (en) | 1996-09-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3419139B2 (en) | Flexible multi-chamber container | |
| JP3016348B2 (en) | Double chamber container | |
| US4805767A (en) | Package system | |
| JP2890143B2 (en) | Medical multilayer film and multi-chamber container | |
| JPH06246886A (en) | Resin laminate and use application thereof | |
| US6063503A (en) | Oxygen-absorbing multi-layer film and method for preparing same | |
| KR20010031996A (en) | Flexible multiple compartment medical container with preferentially rupturable seals | |
| HU216406B (en) | Vessel having a plurality of chambers | |
| JP2002507955A (en) | Containers for anaerobic products | |
| JP3455789B2 (en) | Film for multi-chamber container and multi-chamber container | |
| US5755081A (en) | Heat-sealable, multilayer film containing therein a colorant and method for making a package with such film | |
| JP3815866B2 (en) | Plastic pouch | |
| JPS63179741A (en) | Composite film simultaneously having easily peelable property and heat sealing property | |
| JP2004189307A (en) | Pleated bag | |
| JP2000007050A (en) | Multi-room container | |
| JPH085708Y2 (en) | Infusion bag | |
| JP3853417B2 (en) | Retort pouch | |
| JP3543456B2 (en) | Easy peel seal film and container | |
| JP5088004B2 (en) | Multi-chamber plastic pouch with peelable seal | |
| JP2004501808A (en) | Heat sealable polyolefins | |
| JP3309191B2 (en) | Medical multilayer film and multi-chamber container | |
| JP3019153B2 (en) | Oxygen absorbing multilayer film | |
| KR20120097373A (en) | Vessel incorporating film with enhanced anti-static properties and related methods | |
| JP2004121751A (en) | Double-chamber container and heating seal metal mold used for manufacture of the same | |
| JP2005162292A (en) | Partitioned packaging bag |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20090801 Year of fee payment: 6 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120801 Year of fee payment: 9 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120801 Year of fee payment: 9 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20150801 Year of fee payment: 12 |
|
| EXPY | Cancellation because of completion of term |