JP3018156B2 - Detergent composition - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a detergent composition, and more particularly, to a detergent composition which is excellent in detergency and foaming properties and has a high bactericidal effect. .

[0002]

BACKGROUND OF THE INVENTION Anionic surfactants, especially higher fatty acid salts, are often used in conventional detergent compositions for the purpose of obtaining excellent detergency and foaming power.

On the other hand, detergents, especially those for the body and hair, are required to have a bactericidal and antibacterial effect in addition to the rinsing effect. Therefore, many studies have been made on detergents having a bactericidal and antibacterial effect. Thus, a detergent composition using a cationic germicide as a germicide is known.

[0004] However, when an anionic surfactant and a cationic germicide are used in combination, these complexes are formed, resulting in a problem that not only the detergency is reduced but also the bactericidal effect is not sufficiently exhibited. On the other hand, in order to obtain a sufficient bactericidal effect using an antibacterial agent, it must be used in a large amount, or, as shown in U.S. Pat. No. 5,065,529, soap contains an antibacterial agent and an acyl isethionic acid in a specific ratio. There is a problem that it must be blended.

[0005]

SUMMARY OF THE INVENTION Accordingly, an object of the present invention is to provide excellent detergency and foaming properties as well as excellent bactericidal properties against a wide variety of fungi, and to effectively prevent Kayumi and odor from the body, and It is to provide an inexpensive cleaning composition.

[0006]

Means for Solving the Problems In view of such circumstances, the present invention has made intensive studies, and as a result, a higher fatty acid salt is formulated by combining a specific cationic bactericide and a specific antibacterial agent in a specific amount in combination. It has been found that the synergistic improvement of these bactericidal effects can reduce the amount of the bactericide and the antibacterial agent. Accordingly, the present inventors have found that a detergent composition excellent in all of the detergency, foaming properties and bactericidal properties, and as a result, is excellent in anti-kayumi and deodorant effects, has completed the present invention.

That is, the present invention provides the following component (A):
(B) and (C): (A) The following general formula (1)

[0008]

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[Wherein, R ¹ represents a linear or branched alkyl or alkenyl group having 7 to 21 carbon atoms, and X represents a potassium atom, a sodium atom, an ammonium or an alkanol ammonium]. 5 to 95% by weight of a salt, (B) one or more selected from cationic bactericides represented by the following general formulas (2), (3), (4) and (5) 0.2 to 5 weight%,

[0010]

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[R ² and R ³ each represent a long-chain alkyl group, long-chain alkenyl group or long-chain hydroxyalkyl group having 6 to 14 carbon atoms and a total of 16 to 26 carbon atoms. May be. R ⁴ and R ⁵ have 1 carbon atom
Represents an alkyl group, a hydroxyalkyl group or a polyoxyethylene group having an average number of moles of 10 or less, which may be the same or different. Z ¹ is a halogen atom, an amino acid, a fatty acid, an anionic residue of a phosphate ester, a phosphonate ester, a sulfonate ester or a sulfate ester having a linear or branched alkyl or alkenyl group having 1 to 30 carbon atoms, or polymerization Degree 3
An anionic oligomer or polymer containing a formalin condensate of a sulfonated polycyclic aromatic compound having styrene sulfonic acid or having a hydrocarbon group as a substituent is described. ]

[0012]

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Wherein R ⁶ is a hydrocarbon group having 8 to 14 carbon atoms or

[0014]

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Wherein Z ¹ represents a halogen atom, an amino acid, a fatty acid, a phosphoric acid ester, a phosphonic acid ester, or a sulfonic acid ester having a linear or branched alkyl or alkenyl group having 1 to 30 carbon atoms. Or an anionic residue containing an anionic residue of a sulfate ester or a formalin condensate of a sulfonated polycyclic aromatic compound having styrenesulfonic acid having a degree of polymerization of 3 or more or having a hydrocarbon group as a substituent Shows oligomer or polymer. ]

[0016]

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[Z ² represents gluconic acid, acetic acid or hydrochloric acid. ]

[0018]

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[In the formula, R ⁷ represents a linear or branched alkyl group having 6 to 18 carbon atoms, and Z ³ represents a halogen atom, an amino acid, a fatty acid, a linear or branched alkyl group having 1 to 30 carbon atoms. May have an anionic residue of a phosphoric acid ester, a phosphonic acid ester, a sulfonic acid ester or a sulfuric acid ester having a carboxylic acid group or an alkenyl group, or a styrenesulfonic acid having a degree of polymerization of 3 or more, or may have a hydrocarbon group as a substituent. An anionic oligomer or polymer containing a formalin condensate of a sulfonated cyclic aromatic compound is shown. (C) triclosan, triclocarban, DMDM bidantin, pyrocton auramine, zinc pyrithione,
It contains one or more antibacterial agents selected from the group consisting of selenium disulfide and 3-methyl-4- (1-methylethyl) phenol, and a cationic bactericide of component (B) and (C) It is intended to provide a detergent composition characterized in that the compounding weight ratio (B) / (C) of the component to the antibacterial agent is 0.1 to 25 and does not contain a clay mineral.

[0020]

BEST MODE FOR CARRYING OUT THE INVENTION As the higher fatty acid salt used in the present invention, those having 7 to 21 carbon atoms, particularly preferably 9 to 17 carbon atoms, in the alkyl or alkenyl group of R ^{1 in} the general formula (1) are preferred. X in the general formula (1) is preferably a potassium atom, a sodium atom, ammonium or triethanolammonium.

Component (A) accounts for 5 to 95% by weight of the total composition.
When the composition is in the form of a liquid, the content is preferably 5 to 50% by weight, particularly 8 to 40% by weight, and when the composition is in the form of paste, it is 10 to 80% by weight, particularly 1
The content is preferably 5 to 70% by weight, and when solid, 60 to 98% by weight, particularly preferably 70 to 95% by weight.

The cationic bactericide of the component (B) used in the present invention includes a quaternary ammonium salt represented by the general formula (2), a benzalkonium salt represented by the general formula (3), a benzethonium salt, One or more selected from a chlorhexidine salt represented by the formula (4) and a pyridinium salt represented by the general formula (5). As Z ¹ in the general formulas (2) and (3), a halogen atom is particularly preferable.

Specific examples of the component (B) include benzalkonium chloride, benzethonium chloride, cetylpyridinium chloride, chlorhexidine gluconate, chlorhexidine acetate, and chlorhexidine hydrochloride. For example, benzalkonium chloride and benzethonium chloride are preferable, and further, general formula (3a)

[0024]

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[In the formula, R ^6a represents a linear or branched alkyl or alkenyl group having 8 to 14 carbon atoms.]

A benzalkonium-type fungicide represented by the formula:
For example, benzalkonium chloride is preferred.

The cationic bactericide of the component (B) can be used alone or in combination of two or more kinds. From the viewpoint of bactericidal effect and irritation, 0.2 to 5% by weight is incorporated in the whole composition. , And preferably 0.3 to 4% by weight. Particularly, it is preferable to add 0.4 to 3% by weight.

As the antibacterial agent of the component (C) used in the present invention, triclosan, triclocarban, pyrocton auramine, DMDM hydantoin, zinc pyrithione,
Selenium disulfide, 3-methyl-4- (1-methylethyl)
Phenols may be used alone or in combination of two or more. Among them, preferred are triclosan, triclocarban, DMDM hydantoin, 3-methyl-4.
-(1-methylethyl) phenol.

The blending amount of the component (C) is preferably determined by the ratio with the component (B), and the blending ratio (B) / (C) of the component (B) and the component (C) is 0.1. It is preferable to set it in the range of 25 to 25, especially 0.1 to 20 in order to obtain a synergistic effect of antibacterial properties.

By adding a chelating agent to the detergent composition of the present invention, the sterilizing and antibacterial effects can be further enhanced. The metal chelating agent used in the present invention is not particularly limited as long as it has the ability to chelate metal ions, but aminopolycarboxylic acid chelating agents, aromatic and aliphatic carboxylic acid chelating agents, amino acid chelating agents Agent, ether polycarboxylic acid chelating agent, iminodimethylphosphonic acid (IDP), alkyl diphosphonic acid (ADPA), 1-hydroxyethane-1,
Phosphonic acid chelating agents such as 1-diphosphonic acid (DEQUEST ^™ 2010), hydroxycarboxylic acid chelating agents, phosphoric acid chelating agents, polymer electrolyte (including oligomer electrolyte) chelating agents and dimethylglyoxime (DG) No. Each of these chelating agents may be in a free acid form or in a salt form such as a sodium salt, a potassium salt, and an ammonium salt. In addition, they may be in the form of their hydrolyzable ester derivatives.

Specific examples of the aminopolycarboxylic acid chelating agent include: a) a compound represented by the chemical formula R ⁸ N (Y) ₂ , b) a compound represented by the chemical formula N (Y) ₃ , c) a chemical formula R ^8- A compound represented by N (Y) —CH ₂ CH ₂ —N (Y) —R ⁸ , d) a compound represented by the chemical formula R ⁸ —N (Y) —CH ₂ CH ₂ —N (Y) ₂ , e) A compound represented by the chemical formula (Y) ₂ NR ⁹ -N (Y) ₂ , and f) a compound similar to the compound of e) and containing 4 or more Y, for example, a compound represented by the formula

[0032]

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The compound represented by the following formula:

In the above formula, Y is -CH ₂ COOH or -CH ₂ CH ₂ COOH
R ⁸ represents a group constituting a known chelating agent such as a hydrogen atom, an alkyl group, a hydroxyl group, a hydroxyalkyl group, and R ⁹ represents a known chelating agent of this kind such as an alkylene group or a cycloalkylene group. A group to be used.

A typical example of the aminopolycarboxylic acid chelating agent is ethylenediaminetetraacetic acid (EDT).
A), cyclohexanediaminetetraacetic acid (CDT
A), nitrilotriacetic acid (NTA), iminodiacetic acid (I
DA), N- (2-hydroxyethyl) iminodiacetic acid (HIMDA), diethylenetriaminepentaacetic acid (D
TPA), N- (2-hydroxyethyl) ethylenediaminetriacetic acid (EDTA-OH) and glycol etherdiaminetetraacetic acid (GEDTA), and salts thereof.

Examples of the aromatic or aliphatic carboxylic acid chelating agents used in the present invention include oxalic acid, malonic acid, succinic acid, glutaric acid, adipic acid, itaconic acid, aconitic acid, pyruvic acid, salicylic acid, Examples include acetylsalicylic acid, hydroxybenzoic acid, aminobenzoic acid (including anthranilic acid), phthalic acid, trimellitic acid and gallic acid, and salts, methyl esters and ethyl esters thereof. Examples of the amino acid chelating agent used in the present invention include glycine, serine, alanine, lysine, cystine, cysteine, ethionine, tyrosine, methionine, and salts and derivatives thereof.

Further, examples of the ether polycarboxylic acid-based chelating agent used in the present invention include diglycolic acid, compounds represented by the following formula, analogous compounds thereof, and salts thereof (for example, sodium salts).

[0038]

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Examples of the hydroxycarboxylic acid chelating agent used in the present invention include malic acid, citric acid, glycolic acid, gluconic acid, heptonic acid, tartaric acid, lactic acid and salts thereof. Examples of the phosphate chelating agent used in the present invention include orthophosphoric acid, pyrophosphoric acid, triphosphoric acid and polyphosphoric acid. Examples of the polymer electrolyte (including oligomer electrolyte) chelating agent used in the present invention include acrylic acid polymer, maleic anhydride polymer, α-hydroxyacrylic acid polymer, itaconic acid polymer, Copolymers composed of two or more kinds of constituent monomers of the union and epoxy succinic acid polymers are exemplified. Furthermore, in the present invention, ascorbic acid, thioglycolic acid, phytic acid, glyoxylic acid and glyoxalic acid, and salts thereof can also be suitably used as a chelating agent. Preferred chelating agents include
Ethylenediaminetetraacetic acid (EDTA), succinic acid,
Salicylic acid, oxalic acid, lactic acid, fumaric acid, tartaric acid, 1-
Hydroxyethane-1,1-diphosphonic acid and salts thereof. The metal chelating agent contained 0.1% in the total composition.
-10% by weight, preferably 0.2-5% by weight.

Antibacterial agents other than the above-mentioned antibacterial agents can be added to the composition of the present invention as long as the present invention is not impaired. Examples of such antibacterial agents include those described in the science of preservatives and bactericides for cosmetics and pharmaceuticals (Fragrance Journal, edited by John J. Kabbalah).

Further, an anti-inflammatory agent may be added within a range not to impair the present invention. Such anti-inflammatory agents include glycyrrhizic acid, dihydrocholesterine, allantoin and the like. The detergent composition of the present invention further includes a commonly used amphoteric surfactant such as carbobetaine, sulfobetaine, or hydroxysulfobetaine, or an amine oxide surfactant, an alkanolamide surfactant, or an amide amino acid surfactant. An activator can be added within a range that does not impair the effects of the present invention.

The cleaning composition of the present invention further comprises (A)
Anionic surfactants other than the components can be blended within a range that does not impair the effects of the present invention. Examples of such anionic surfactants include polyoxyalkylene alkyl ether carboxylic acids or salts thereof, alkyl sulfates, and alkyl sulfates. Sulfonic acid or salt thereof, alkylbenzene sulfonic acid or salt thereof, polyoxyalkylene alkyl ether sulfate, alkyl phosphoric acid or salt thereof, polyoxyalkylene alkyl ether phosphoric acid or salt thereof, polyoxyalkylene alkyl amide ether carboxylic acid or salt thereof An alkyl sulfosuccinate, a polyoxyalkylene alkyl ether sulfosuccinate, an N-acyl-N-methyltaurate, an N-acyl sarcosine salt, an α-olefin sulfonic acid or a salt thereof, Silylated isethionate, acylated glutamic acid or a salt thereof, and the like, among which alkyl sulfate, polyoxyalkylene alkyl ether sulfate, alkyl phosphate, polyoxyalkylene alkylamide ether carboxylic acid, Acylated isethionate, polyoxyalkylene alkyl ether carboxylic acid, and polyoxyalkylene alkyl ether sulfosuccinate.

The detergent composition of the present invention can be produced according to a usual method, and can be in the form of a solid, paste, gel, liquid or the like. It is also suitable as a body cleanser.

[0044]

EFFECTS OF THE INVENTION The detergent composition of the present invention has excellent detergency and foaming properties, and has a higher bactericidal effect and a broader germicidal spectrum when used in combination with an antibacterial agent and a bactericide. It can provide itching prevention and deodorant effects.

[0045]

EXAMPLES Hereinafter, the present invention will be described in more detail with reference to examples, but the present invention is not limited to these examples. In addition, the compounding amount of each component in the following examples was shown on the basis of the effective component. “%” Indicates “% by weight”.

Example 1 A cleaning agent having the following composition was prepared and subjected to a sterilization test.

[0047]

TABLE 1 Potassium coconut oil fatty acid 10% ^* Benzalkonium chloride 0, 0.2, 0.6, 0.8, 0.9, 0.95, 1.0% Triclosan 0,0.05,0. 1,0.2,0.4, 0.8, 1.0% water balance _{*: C 12 / C 14 =} 50/50 ( weight ratio), hereinafter the same

In the above composition, the total amount of benzalkonium chloride and triclosan was blended so as to be 1.0% by weight, and the bactericidal effect against Escherichia coli at that time is shown in Table 2. (Disinfection test method) Test bacteria (Escherichia coli IFO3
972) used was a culture solution pre-cultured in an SCD medium (manufactured by Nippon Pharmaceutical Co., Ltd.). 0.1 ml of culture solution (10 ⁹ -1
0 ¹⁰ cell / ml) in sterile water at a predetermined concentration (composition dilution × 1, × 2, × 4, × 8, × 16, × 32, × 64,
(× 128, × 256, × 512) were inoculated into 10 ml of each detergent composition. After a certain time (2.
Every 5, 5, 10, 15 minutes), one loopful of loop was taken, inoculated into a growth medium, and cultured at 30 ° C. for 3 days to determine the presence or absence of bacterial growth. In the sterilization test method, when growth was not observed at all dilution concentrations and all reaction times, the number of sterilization areas was expressed as 40.

[0049]

[Table 2]

As can be seen from Table 2, when the total blending weight of benzalkonium chloride and triclosan was set to 1.0%, a clear synergistic effect was observed when both of them were used in combination as compared with the bactericidal effect of each.

Example 2 Evaluation of the bactericidal effect was carried out in accordance with the bactericidal test method of Example 1 using the detergents having the composition shown in Tables 3 and 4.
However, the test bacteria were Staphylococcus aureus IFO 12732 and Es
This was performed using cherichia coli IFO 3972. Further, foaming and deodorant effects were evaluated by the following methods and criteria. The results are shown in Tables 3 and 4.

(Evaluation Method and Evaluation Criteria for Deodorant Effect) For each cleaning composition, a usage test was conducted once a day for 2 weeks by panelists of 5 men and women. The deodorant effect was evaluated by a professional evaluator based on the following criteria for body odor 24 hours after the final washing.

(Evaluation method) 5: No smell 4: Slight smell 3: Smell 2: Very smell 1: Very strong smell

The results were expressed as an average value of 10 panelists as a deodorant effect according to the following criteria. ◎: Good for 4.0 or more ○: Somewhat good for 3.2 to 3.9 △: Normal for 2.5 to 3.1 ×: Poor for 2.4 or less

(Method for Evaluating Foaming and Evaluation Criteria) At the same time, foaming when the panel was washed with each detergent composition was evaluated according to the following criteria.

(Evaluation Criteria) 5: Foaming felt good 4: Foaming felt somewhat good 3: Foaming felt normal 2: Foaming felt not very good 1: Foaming not good I felt

The results were expressed as the average of 10 panelists according to the following criteria. ◎: 4.5 or more good ○: 3.5 to 4.4 slightly good △: 2.5 to 3.4 normal ×: 2.4 or less bad

[0058]

[Table 3]

[0059]

[Table 4]

As shown in Tables 3 and 4, the product of the present invention in which the cationic bactericide (B) and the antibacterial agent (C) were used in combination was excellent in foaming, and had good bactericidal and body odor suppressing effects. Was.

Example 3 (Body shampoo) A body shampoo having the following composition was produced by a conventional method.

[0062]

[Table 5] Coconut oil fatty acid potassium 21% Lauroyl diethanolamide 1% ^* Benzalkonium chloride 0.5% Triclocarban 0.1% Disodium succinate 0.4% Fragrance 0.5% Purified water Balance

The obtained body shampoo was excellent in washing performance and foaming property, and had a high deodorant effect.

Example 4 (Body shampoo) A body shampoo having the following composition was produced by a conventional method.

[0065]

TABLE 6 Potassium laurate 16% Potassium palmitate 2% Polyoxyethylene (2) sodium lauryl ether sulfate 1.5% Lauroyl diethanolamide 1% ^* Benzalkonium chloride 1% Triclosan 0.1% Disodium ethylenediamine tetraacetate 1.0% Fragrance 0.5% Purified water Balance

The obtained body shampoo was excellent in washing performance and foaming property, and had a high sterilizing effect.

Example 5 (paste soap) A paste soap having the following composition was produced by a conventional method.

[0068]

[Table 7] Coconut oil fatty acid sodium 60% Lauroyl diethanolamide 1% ^* Benzalkonium chloride 0.8% Triclocarban 0.4% Ethylenediaminetetraacetic acid disodium 0.8% Fragrance 0.5% Purified water Balance

The obtained paste soap was excellent in cleaning performance and foaming property, and had a high deodorant effect.

Example 6 (Solid soap) A solid soap having the following composition was produced by a conventional method.

[0071]

Table 8 Sodium laurate 85% Coconut oil fatty acid sodium 8% Lauroyl monoethanolamide 1% Benzethonium chloride 0.5% Triclosan 0.1% Triclocarban 0.1% Disodium ethylenediaminetetraacetate 0.5% Fragrance 0. 5% purified water balance

The obtained solid soap was excellent in washing performance and foaming property, and had a high deodorant effect.

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification code FI C11D 3/26 C11D 3/26 3/34 3/34 3/36 3/36 9/28 9/28 9/30 9/30 9/32 9/32 9/34 9/34 9/36 9/36 10/06 10/06 (72) Inventor Yasuhiro Doi 1334 Minato, Wakayama City, Wakayama Prefecture Kao Corporation Research Laboratory (56) References JP Akira 63-139998 (JP, A) (58) Fields investigated (Int. Cl. ⁷ , DB name) C11D 9/26 A61K 7/50 C11D 1/04 C11D 3/20 C11D 3/24 C11D 3/26 C11D 3 / 34 C11D 3/36 C11D 9/28 C11D 9/30 C11D 9/32 C11D 9/34 C11D 9/36 C11D 10/06

Claims (2)

(57) [Claims] 1. The following components (A), (B) and (C): (A) the following general formula (1): [Wherein, R ¹ represents a linear or branched alkyl or alkenyl group having 7 to 21 carbon atoms, and X represents a potassium atom, a sodium atom, ammonium or an alkanol ammonium]. 95% by weight, (B) one or more selected from the cationic fungicides represented by the following general formulas (2), (3), (4) and (5): 0.2 to 5% by weight; Embedded image [R ² and R ³ each have 6 to 14 carbon atoms and a total of 16 to
26 represents a long-chain alkyl group, a long-chain alkenyl group, or a long-chain hydroxyalkyl group, which may be the same or different. R ⁴ and R ⁵ are alkyl groups having 1 to 3 carbon atoms, shows a hydroxyalkyl group or an average addition mole number of 10 or less polyoxyethylene groups, or different phases the same as each other. Z ¹ is a halogen atom, an amino acid, a fatty acid, an anionic residue of a phosphate ester, a phosphonate ester, a sulfonate ester or a sulfate ester having a linear or branched alkyl or alkenyl group having 1 to 30 carbon atoms, or polymerization An anionic oligomer or polymer containing a formalin condensate of a sulfonated polycyclic aromatic compound having styrene sulfonic acid having a degree of 3 or more or having a hydrocarbon group as a substituent is shown. [Chemical formula 3] [Wherein, R ⁶ is a hydrocarbon group having 8 to 14 carbon atoms or Wherein Z ¹ represents a halogen atom, an amino acid, a fatty acid, a phosphoric ester, a phosphonate, a sulfonate or a sulfate having a linear or branched alkyl or alkenyl group having 1 to 30 carbon atoms. Oligomer or polymer containing a formalin condensate of a sulfonated polycyclic aromatic compound having styrenesulfonic acid having a polymerization degree of 3 or more or having a hydrocarbon group as a substituent Is shown. [Chemical formula 5] [Z ² represents gluconic acid, acetic acid or hydrochloric acid. [Formula 6] [Wherein, R ⁷ represents a linear or branched alkyl group having 6 to 18 carbon atoms, and Z ³ represents a halogen atom, an amino acid, a fatty acid, a linear or branched alkyl group or alkenyl having 1 to 30 carbon atoms. Anionic residue of a phosphoric acid ester, a phosphonic acid ester, a sulfonic acid ester or a sulfuric acid ester, or a polycyclic aromatic compound having styrenesulfonic acid having a degree of polymerization of 3 or more or having a hydrocarbon group as a substituent An anionic oligomer or polymer containing a formalin condensate of a sulfonated group compound is shown. (C) triclosan, triclocarban, DMDM bidantin, pyrocton auramine, zinc pyrithione,
It contains one or more antibacterial agents selected from the group consisting of selenium disulfide and 3-methyl-4- (1-methylethyl) phenol, and a cationic bactericide of component (B) and (C) A detergent composition characterized in that the compounding weight ratio (B) / (C) of the component to the antibacterial agent is 0.1 to 25 and does not contain a clay mineral. 2. The cleaning composition according to claim 1, further comprising a metal chelating agent.