JP3072596B1 - Absorbent covering and protecting material for wounds consisting of cellulose sponge - Google Patents

Abstract

The present invention has excellent absorbability and liquid retention properties, does not generate falling fibers, hardly dries a wound part, and has a certain shape retention property to facilitate attachment to the wound part. The present invention provides an absorptive wound-covering and protecting material for wounds which can be applied directly to the wound without hindering the healing of the wound, and a method for protecting and covering the wound. SOLUTION: A sponge stock solution containing no reinforcing fibers, which is a mixture of viscose and crystalline sodium sulfate as main raw materials, is subjected to a heat treatment in a relatively low temperature range of 35 ° C to 70 ° C to solidify to a certain thickness. It is formed into a sheet having shape-retaining properties, and is directly applied so as to cover the wound, thereby absorbing the exudate at the wound and protecting the wound.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an absorbent covering and protecting material for a wound using a cellulose sponge which can be directly applied to the wound for the purpose of absorbing exudate at the wound and covering and protecting the wound. The present invention relates to a protection method, and more particularly to an absorptive wound-covering protective material that can be directly applied to a pin insertion portion or a drain-tube insertion portion of an external fixator into which a pin or a drain tube is inserted, and a method of protecting and covering the wound. .

[0002]

2. Description of the Related Art As an absorptive covering / protecting material for a wound, it is a soft woven fabric which is thin and soft and has excellent hygroscopicity. Later, gauze that has been refined, bleached, and disinfected is generally used for medical purposes. For example, in the pin insertion portion where the pin of the external fixator is inserted, epithelial cells appear on the wound surface 5 to 7 days after the operation, fibroblasts generate collagen and various substrates, and angiogenesis occurs. As it is said that it will become active, there is no infection as soon as possible after surgery,
It is good to keep the pinholes shrinking and no scab formation.At this time, there is no foreign matter, no necrotic tissue, no microorganisms, and an environment where the temperature, humidity, and oxygen concentration are maintained at appropriate levels. Therefore, a so-called split gauze having a cut in the pin insertion portion has been inserted.

As another absorptive covering / protecting material for wounds, the use of a polyurethane or polyester sponge has been studied. However, water absorption is poor, and in this case, blisters are formed on the skin, which is not preferable. So far, no absorbent absorbent covering for wounds has been found which is equivalent to or better than gauze.

[0004]

However, even with such a gauze which is currently the most desirable absorbent covering and protecting material for wounds, the gauze has poor absorbency and liquid retention property, and is not suitable for wounds. If the amount of leachate is too large, it will not be able to be properly absorbed, resulting in leakage, making clothes and sheets dirty and unsanitary, or having the inconvenience that must be replaced frequently to prevent leakage of leachate In addition, if the exudate is not absorbed by the gauze, a scab is formed, and the eschar is engulfed by the eschar, and self-sensitizing dermatitis is caused by the exudate, prolonging the healing of the wound with rash and itching. Sometimes.

In addition, since the above-mentioned gauze is liable to generate falling fibers (lint), if the wound is directly coated, the falling fibers easily adhere to the wound, which is not very desirable from a hygiene point of view. Since the wound is easily dried, for example, if the split gauze is inserted into the wound such as the insertion part of the external fixing pin or the insertion part of the drain tube, the falling fiber is dried with the attached fibers. In many cases, it is very difficult to remove the split gauze. In particular, when the wound is dried, the gauze body is peeled off from the wound because only the fallen fibers separated from the gauze body do not adhere to the wound and dry, but the gauze body adheres to the wound and dry. In some cases, the scabs remove new cells, causing pain to the patient and prolonging the wound healing.

Further, since the above-mentioned gauze is flexible and cannot be fixed as it is, in order to fix it to the pin of the external fixator, it is necessary to mount a compression fixing rubber plate thereon. In this case, if the wound portion is swollen, the compression-fixing rubber plate may leave an indentation and may cause rash around the wound portion, which is not desirable.

[0007]

DISCLOSURE OF THE INVENTION The present invention addresses these problems, and has excellent absorbability and liquid retention properties, does not cause falling fibers, and has a wound that is difficult to dry. It is an object of the present invention to provide an absorptive covering and protecting material for wounds which can be applied directly to the wound and has a certain shape-retaining property and which can be easily applied to the wound, and a method for protecting the covering. It is.

The inventor of the present application has made intensive studies to solve such a problem, and as a result, has found that Japanese Patent Application No. 9-538742 (W).
The three-dimensional cellulose sponge disclosed in O97 / 41169) disinfects wounds and abrasions, disinfects the affected area before surgery, absorbs fluid during surgery, disinfects wounds after surgery, disposes of eyes and cavities, etc. Not only is it suitable as a disinfectant / absorbent material with a relatively short contact time with the wound for the purpose of disinfecting mucous membranes, etc. To be applied as an absorptive covering and protecting material for wounds that protects the wound without generating fibers (lint), keeps appropriate wetness around the wound, and is easy to wear, and has a relatively long contact time with the wound. I found that it is possible.

That is, the invention of the present application is to provide a sponge stock solution containing no viscose and crystalline sodium sulfate as a main raw material, which does not contain reinforcing fibers, and is subjected to a heat treatment at a temperature in the range of 35 ° C. to 70 ° C. to be thinly solidified. Cellulose sponge formed into a sheet form from the above, or the sponge stock solution is coagulated until fluidity is lost by a first temperature holding step of performing a heat treatment at a temperature range of 35 ° C to 70 ° C, and subsequently from 90 ° C to It is a cellulose sponge that is formed into a sheet from the beginning by completely coagulating by a second temperature holding step of performing a heat treatment in a temperature range of 100 ° C., such that the wound is directly covered with such a cellulose sponge. By applying and fixing, it absorbs exudate from the wound and protects the wound A.

The absorptive covering / protecting material for a wound according to the present invention may be modified in form depending on the use (application site). For example, a wound site, a pressure wound, a burn site, a skin transplant site, etc. Absorption and protection of leachate in
When used for the purpose of absorbing intestinal fluid after the construction of a colostomy or urinary tract stoma, it may be a simple thin sheet type without incision, and the absorption and protection of exudate at the pin insertion part of the external fixator When used for the purpose of absorbing and protecting the leachate in the drain insertion part, use a cantilever type external fixator type (a thin sheet with a notch for inserting the external fixator pin or drain tube). ) Or a ring type external fixator type (in which a notch and an insertion hole for inserting a pin or a drain tube of the external fixator are formed in a thin sheet).

As shown in FIG. 2, the wound-shaped absorbent covering / protecting material in which the cut is formed is, for example, a linear cut (2) extending from one end (10a) of the cellulose sponge (10) to a substantially central portion. ) And an insertion hole (3) partially notched at the substantially central portion to form an absorbent covering / protecting material for wound (1) (see (a)) or a cellulose sponge (10). Forming a linear cut (2) from one end (10a) to a substantially central portion and a radial cut (4) extending in at least two directions at the substantially central portion; Or cellulose sponge (1)
0), an opening cutout (5) extending from the one end (10a) to the substantially central portion and an insertion hole (3 ') partially notching the substantially central portion to form an absorptive covering and protecting material for a wound ( 21) (see (c)), and further, an opening cut (5 ') extending from one end (10a) of the cellulose sponge (10) to a substantially central portion, and a radial cut extending in at least two directions at the substantially central portion. By forming (4 ′) and (4), an absorbent covering / protecting material for wound (31) can be considered (see (d)). When the V-shaped introduction notch (6) is formed on one end (10a) side of the cellulose sponge (10) provided with the linear notch (2), the pin or the drain tube of the external fixator is formed. In addition, the position, number and size of the cuts provided in the cellulose sponge can be appropriately changed as necessary, such as the application location.

The absorbent covering and protecting material for a wound having such a cut, for example, the absorbent covering and protecting material for a wound (1) having a cut shown in FIG.
As shown in FIG. 1, the notch (2) is easily opened by pushing the pin (P) of the external fixator fixed to the leg (A) so as to align the introduction notch (6) with the pin (P). The pin (P) is inserted into the hole (3), and the absorbent covering protective material for wound (1) is attached so as to cover the wound, so that the exudate from the wound is absorbed and the wound is absorbed. Covering and protection.

Here, a general method for producing a cellulose sponge used in the present invention will be described. The cellulose sponge of the present invention is obtained by mixing viscose with crystalline sodium sulfate and a polyol compound, and, if necessary, a surfactant, and pouring the obtained sponge stock solution thinly in a mold, followed by heat treatment at a relatively low temperature. Or by performing a heat treatment in a first temperature holding step at a relatively low temperature and a second temperature holding step at a higher temperature than the first temperature holding step. In addition, the cellulose sponge of the present invention is manufactured by providing cuts as needed (location to be applied).

As for viscose, it is usually industrially advantageous to use viscose for viscose rayon.
Can be used effectively. As the viscose for viscose rayon, ordinary viscose, viscose for strong rayon and the like can be used, and there is no particular limitation. The degree of polymerization of the cellulose component of viscose is from 200 to 400, particularly preferably from 250 to 350. Cellulose having a degree of polymerization higher than 400 is not preferable because the obtained sponge becomes hard, and cellulose lower than 200 is not preferable because the obtained sponge becomes weak. Specifically, the cellulose concentration is 5 to 10% by weight, the alkali concentration is 3 to 8%, the Hotten-roth value is 5 to 12, the falling ball viscosity is 20 to 300 sec / 20.
And those having a γ value in the range of 45 to 70 are preferably used.

When viscose having a cellulose concentration of less than 5% by weight is used, the viscosity of the viscose becomes low, and sedimentation of crystalline sodium sulfate occurs in the sponge stock solution, resulting in non-uniform pores of the sponge. Conversely, when viscose having a cellulose concentration higher than 10% by weight is used, the viscosity of the viscose increases, making it difficult to uniformly mix the crystalline sodium sulfate. As a result, the pores of the resulting cellulose sponge become non-uniform and uniform. A cellulose sponge having high flexibility and uniform strength cannot be obtained, which is not preferable.

In the case of viscose having an alkali concentration of less than 3%, viscose having a γ value of less than 45, or viscose having a Hotten-roth value of less than 5, the sponge stock solution is liable to solidify. Solidification occurs during the operation of kneading crystal sodium sulfate and filling in a mold, which is not preferable. On the other hand, in the case of viscose having an alkali concentration higher than 10%, in the case of viscose having a γ value higher than 70, or in the case of viscose having a Hottenroth value higher than 12, the sponge stock solution hardly solidifies, and the coagulation step It takes time and is not preferable.

Further, when the falling ball viscosity is lower than 20 sec, the viscose viscosity becomes too low, and sedimentation of crystalline sodium sulfate occurs in the sponge stock solution, resulting in non-uniform pores of the sponge, which is not preferable for the same reason as described above. . On the other hand, if it is higher than 300 sec, the viscose viscosity is too high,
Uniform mixing of the crystalline sodium sulfate becomes difficult, resulting in non-uniform pores of the sponge, which is not preferable for the same reason as described above.

The crystalline sodium sulfate is suitably one having an average particle diameter of 0.2 mm or less, particularly preferably in the range of 0.01 mm to 0.2 mm. If the average particle size of the crystalline sodium sulfate is larger than 0.2 mm, the diameter of the pores (cells) constituting the cellulose sponge becomes large, which adversely affects the shrinkage during drying and the swelling recovery rate. Further, the strength of the obtained cellulose sponge varies.

The amount of crystalline sodium sulfate added is 50 to 100 times the amount of cellulose in viscose, preferably 60 to 100 times.
It is preferable that the amount be up to 80 times (weight ratio). When the added amount of the crystalline sodium sulfate is less than 50 times the weight of the cellulose in the viscose, the apparent density when dried becomes too high,
The pore walls are thicker, and the resulting sponge is less flexible. Further, when the addition amount is more than 100 times, the viscosity of the sponge stock solution increases in the mixing operation,
The strength of the sponge obtained is too low, which is not good.

By adding a surfactant to viscose, the flowability of the sponge stock solution can be improved, that is, the viscosity can be appropriately reduced. , The workability can be improved, and a cellulose sponge having a stable quality such as strength and flexibility can be obtained. Addition of surfactant to viscose is performed as needed, alkali concentration, γ value, and hotten Roth value In the case of a sponge stock solution using a relatively high viscose,
The flowability is high enough that no surfactant needs to be added.

As the surfactant, an anionic surfactant and / or a nonionic surfactant can be used. Cationic surfactants are not preferred because they modify the viscose. Particularly preferred surfactants are sodium dodecyl sulfate, sorbitan monooleate, and ethylene oxide adducts of these surfactants [eg, sorbitan monooleate + 20 (C ₂ H ₄ O)].
At least one selected from the group consisting of: If any surfactant is added to viscose in advance, it is easy to use.

The addition amount is 1.0% by weight based on the viscose.
The following is preferred. It is more preferably 0.02 to 1.0% by weight, particularly preferably 0.1 to 1.0% by weight. If the amount is less than 0.02% by weight, there is no addition effect.
It is wasteful to add 1.0% by weight or more because the addition effect does not change. When the surfactant is solid, it is preferable to add the surfactant by mixing it with polyethylene glycol described below in advance.

Among the known polyol compounds as an additive to viscose, glycerin and the like cannot be used because the sponge becomes hard, but the cause is unknown. In addition, when adding polyethylene glycol to viscose, it is preferable to add a part first and then adjust the amount of addition by adding the remaining polyethylene glycol together with the surfactant.

The mixing of each of the above raw materials is based on viscose,
It is common practice to mix the polyalkylene glycol, then the surfactant if necessary, and finally mix the sodium sulfate. Further, if necessary, a pigment, an X-ray non-transparent material such as barium sulfate, or the like can be mixed in this mixing step. The mixing device is not particularly limited as long as it has a cooling mechanism that can be adjusted so that the viscose temperature does not become 20 ° C. or higher. When the viscose temperature exceeds 20 ° C., the solidification of the viscose starts, and it is difficult to form uniform pores. Crystalline sodium sulfate, polyalkylene glycol and a surfactant can be added and mixed at the same time to viscose. These three types can be mixed simultaneously. However, crystal sodium sulfate is added to viscose to which polyalkylene glycol and a surfactant have been added in advance. Is preferred.

The filling step of filling the mold with the sponge stock solution obtained by the mixing step may include heating the sponge stock solution thinly filled in the forming mold at a relatively low temperature, or The heat treatment is performed in a first temperature holding step at a relatively low temperature and a second temperature holding step at a higher temperature than the first temperature holding step.

The material of the molding die is essentially a heat resistant temperature of 9
If it is 0 ° C. or higher, it can be used. For example, a material made of plastic, glass, or coated with ceramic plastic may be used. Specifically, as the plastics, for example, PTFE, polypropylene, heat-resistant vinyl chloride, high-density polyethylene and the like are preferable because they are relatively inexpensive and easy to remove. These molding materials have a good sponge release property compared to those made of metal, and therefore, without having to apply a release agent in advance, it is possible to remove a sponge having a good appearance, There is no worry about the release agent remaining.

The sponge stock solution filled in the mold was 35%.
30 minutes or more at 24 degrees C or more and 70 degrees C or less (first temperature range)
It is important in the present invention to perform the temperature holding step within a period of time. Particularly preferably, at 35 to 45 ° C for 60 minutes to 5 minutes.
It is better to keep the time. Specifically, the sponge stock solution is maintained at the first temperature range until the fluidity of the sponge solution disappears. If the first temperature range is lower than 35 ° C., it takes too much time and is not industrial. Further, when a heat treatment exceeding 70 ° C. in the coagulation step performed in the conventional production of cellulose sponge is performed in the first temperature holding step, bubbles of carbon disulfide are generated rapidly, and the pores of the obtained sponge are uneven. , Resulting in non-uniform flexibility. Further, if the first temperature range is higher than 70 ° C., since solidification proceeds from the surroundings, an ear is generated in a portion in contact with the molding die, and the strength of the obtained cellulose sponge is different from the surroundings and the inside thereof. It is no longer suitable for use.

Although the sponge stock solution can be completely coagulated in the first temperature holding step, it is industrially disadvantageous because coagulation requires a long time. Therefore, after the first temperature holding step, a second temperature holding step consisting of maintaining the temperature within a range of 30 minutes to 5 hours by a high-temperature heat treatment of 90 ° C. or more (second temperature range) is not added. This is an industrially advantageous means because the coagulation time can be shortened. More preferably, the temperature is in a range of 1 hour to 4 hours at a temperature of 90 ° C. or more and 100 ° C. or less. When the second temperature range is less than 90 ° C., it is difficult to have a fixed shape after demolding. As a result, the dispersion of the liquid absorption rate and the wet strength are increased, and the performance of the cellulose sponge for medical use is reduced as a whole. In addition, if the heat treatment in the second temperature holding step is incomplete, an uncoagulated sponge stock solution is eluted during washing with water, resulting in insufficient sponge formation.

The first temperature holding step and the second temperature holding step are not particularly limited as long as the temperature can be maintained uniformly. However, the step of pouring the undiluted sponge solution into a mold placed in warm water is performed uniformly in the heat treatment. It is convenient to perform it.

Demolding can be easily performed because the sponge stock solution contracts when it solidifies, but care must be taken when stenosis or deformation occurs at this stage because the shape at that time is memorized.

The molded product obtained by the demolding step is subjected to a post-treatment comprising a water washing step, an acid regeneration step, a desulfurization step, a bleaching step and a neutralization step. The washing process is
It is preferable to wash with high-temperature water until the crystalline sodium sulfate added to the sponge stock solution is completely eluted, and then perform normal-temperature water washing. This washing removes the surfactant together with the sodium sulfate. If the sodium sulfate and the surfactant remain, the material becomes unsuitable for medical use.

Next, the acid regenerating step (cellulose regenerating step) is carried out in substantially the same manner as the usual viscose rayon producing step, for example, at a concentration of about 40 to 100 g.
This is carried out by immersing the molded body after the water-washing treatment in a 1 / L aqueous sulfuric acid solution. By this step, the viscose is completely regenerated into cellulose. A particularly preferred range of the aqueous sulfuric acid solution used is 50 to 90 g / L. When the concentration of the aqueous sulfuric acid solution is higher than 100 g / L, the surface of the sponge may be roughened. If the amount is less than 40 g / L, the reproduction becomes slow. The immersion time is preferably 2 to 30 minutes. If it is shorter than 2 minutes, complete regeneration will not be achieved. Even if it is performed for 30 minutes or more, since the reproduction has been completed by that time, no further progress is made. The temperature is preferably 20 to 50 ° C. If the temperature is lower than 20 ° C., the regeneration becomes slow, which is not preferable. If the temperature is higher than 50 ° C., the surface of the obtained sponge may be unfavorably roughened.

The desulfurization step (alkali washing step)
The molded body that has undergone the acid regeneration step is treated with an aqueous sodium hydroxide solution or an aqueous sodium sulfide solution. By this treatment, the residual sulfur content in the sponge can be reduced. It is carried out by immersing in a mixed solution of an aqueous solution of sodium hydroxide having a concentration of 1 to 4 g / L and an aqueous solution of sodium sulfide having a concentration of 0.5 to 2 g / L. 1 g of sodium hydroxide aqueous solution
When the concentration is lower than the L concentration or when the aqueous solution of sodium sulfide is lower than the concentration of 0.5 g / L, no curing can be obtained. When the concentration of the aqueous sodium hydroxide solution is higher than 4 g / L or the concentration of the aqueous sodium sulfide solution is higher than 2 g / L, the sponge surface may be roughened. The temperature of the immersion liquid is preferably from 40 to 80C. The immersion time is preferably from 10 to 60 minutes. When the temperature is lower than 40 ° C. or when the immersion time is shorter than 10 minutes, the effect is hardly obtained. on the other hand,
When the temperature is higher than 80 ° C. or when the immersion time is longer than 60 minutes, the sponge surface may be roughened. Specifically, it is immersed in a mixed solution of an aqueous solution of sodium hydroxide having a concentration of 1 to 4 g / L and an aqueous solution of sodium sulfide having a concentration of 0.5 to 2 g / L at 40 ° C. to 80 ° C. for 10 to 60 minutes for treatment.

Further, in the bleaching step, it may be immersed in an aqueous solution of sodium hypochlorite or an aqueous solution of hydrogen peroxide having a concentration of 0.1 to 3 g / L at room temperature for 10 to 30 minutes. If the concentration of sodium hypochlorite or the concentration of hydrogen peroxide is lower than 0.1 g / L, the bleaching effect cannot be obtained. Further, when the concentration of sodium hypochlorite or the concentration of hydrogen peroxide is 3 g /
If it is higher than L, the sponge surface may be rough. The temperature of the immersion liquid is preferably 20 to 50C. Immersion time is 10
-30 minutes are preferred. When the temperature is lower than 20 ° C. or when the immersion time is shorter than 10 minutes, it is difficult to obtain the bleaching effect. On the other hand, when the temperature is higher than 50 ° C. or when the immersion time is longer than 30 minutes, the sponge surface may be roughened.

Then, after performing a neutralization step of washing and removing the chemicals in the bleaching step so that the chemicals do not remain, drying is performed, and FIG.
And as shown in FIG. 3, if necessary, a cut suitable for the application point (for example, a cut matched between the pins of the external fixator) is made.

[0036]

EXAMPLES Hereinafter, specific production examples of the absorbent covering and protecting material for wounds comprising the cellulose sponge of the present invention and a method for protecting and covering wounds will be described. Examples of the production of the absorptive covering and protecting material for wounds include cellulose 7 having a degree of polymerization of 320.
% Viscose containing 6% by weight of alkali and 6% by weight of alkali, polyethylene glycol having an average molecular weight of 400 with respect to 3% by weight of viscose, sodium dodecyl sulfate with 0.4% by weight of viscose, and an average particle size of 0.12 mm. A certain amount of crystalline sodium sulfate was added to 65 times the weight of cellulose and mixed to prepare a sponge stock solution. This sponge stock solution was made of heat-resistant polyvinyl chloride and had an inner size of 200 mm × 200 mm × 2.
Fill into a mm dish. And 6 in a water bath at 40 ° C.
The mixture is held for 0 minutes, then solidified by performing a heat treatment consisting of holding it in a water bath at 90 ° C. for 120 minutes, and then extracted from the mold.

Next, deblunting is performed with boiling water at 90 ° C. or higher, and the resulting sponge intermediate is placed in a 50 g / L aqueous sulfuric acid solution.
The cellulose was immersed for 0 minutes to regenerate the cellulose.
It was immersed in a mixed solution of an aqueous L sodium hydroxide solution and a 1.3 g / L aqueous sodium sulfide solution at 50 ° C. for 10 minutes to perform a desulfurization treatment. Then, after being immersed in a 0.2 g / L aqueous solution of sodium hypochlorite at room temperature for 10 minutes to perform desulfurization and bleaching treatment, washed and dried, cut into a size suitable for the application, and applied to an application point. Accordingly, a cut was made in accordance with the pin or drain tube of the external fixator to obtain a rectangular sheet-shaped absorbent covering and protecting material for a wound made of cellulose sponge.

Next, as a comparative example, in order to confirm the effect when each of the rectangular sheet-shaped absorbent covering and protecting materials formed as described above was applied to the wound, the adhesion of the dropped fibers and the leaching solution were examined. The quality of each item of absorbency, wound condition, itching, and time required for replacement was evaluated by comparing and evaluating with the conventional gauze or polyurethane sponge. As for the judgment method, ○
The evaluation was made in three stages, marked with a mark, marked as unsatisfactory but not problematic, and marked as x, marked as problematic. The results are shown in Table 1 below.

[0039]

[Table 1]

As shown in Table 1 above, the absorbent covering-protecting material for wounds according to the present invention has no adherence of fallen fibers to wounds, good absorbability of exudate, and no itching.
In addition, the replacement of the coating protective material requires little effort, and compared to the conventional gauze, which is an absorbent coating protective material for wounds, the attachment of falling fibers, the absorption of exudate, the state of wounds, Itching and labor required for replacement are excellent in all items, and even in comparison with the conventional polyurethane sponge which is an absorbent covering protective material for wounds, it is excellent in all items except for the labor required for replacement. You can see that there is.

[0041]

As described above, the absorbent covering protective material for wounds according to the present invention is excellent in absorbency and liquid retention, and thus is particularly effective for cases with a large amount of exudate. It can eliminate the hassle of polluting sheets and making them unsanitary or having to replace them frequently to prevent leakage of leachate,
Self-sensitizing dermatitis due to exudate is prevented, crust formation is suppressed, epithelialization is not hindered, and there is no fear that new cells are caught with the crust, and healing of the wound is not hindered.

In addition, the absorbent covering protective material for wounds of the present invention is a material in which falling-off fibers are hardly generated (lint-free).
Even if the wound is directly covered, it can prevent the falling fibers from adhering to the wound, and since it has a sheet-like shape, it is easy to adhere to the wound, and also maintains an appropriate humidity at the wound, , With the wound being dried, the blood and the like absorbed by the wound-absorbent coating protective material are dried,
Even if the wound-portion absorbent covering and protecting material adheres to the skin, the wound-portion absorbing covering and protecting material becomes flexible and easily peeled off by including physiological saline, and does not peel off the neoplastic cells. It can be replaced without causing pain to the patient.

Further, since the absorbent covering protective material for wounds of the present invention is a thin sheet having shape-retaining properties, it can be easily attached to the wounds. For example, it can be inserted into the pins of the external fixator. Even in the case of mounting, it can be easily fixed by mounting so that the absorbent covering protective material for a wound in which a cut is formed is inserted toward the pin. In addition, according to such a mounting method, even if the wound is swollen, it can be easily mounted and fixed without causing pain or forming indentations.

[Brief description of the drawings]

FIGS. 1A and 1B are explanatory views showing a method of applying an absorptive covering and protecting material for wounds according to the present invention.

FIG. 2 is a front view showing (a) an absorptive wound-covering and protecting material having a cut according to the present invention; (b) a front view showing another absorptive absorptive covering-protecting material having a cut according to the present invention;
(C) A front view showing another absorbent covering protective material for wounds having a cut of the present invention.

[Explanation of symbols]

 A: Legs P: Pins of external fixator 1, 11, 21, 31 ... Absorbent covering protection for wound Material 2 ··· Linear cut 3,3 '······· Insertion hole 4,4' ······ Radial cut 5,5 ′ ······· Opening cut 6 ··· Introduction cut 10 ··· Cellulose sponge 10a ···· ····edge

────────────────────────────────────────────────── ─── Continuing on the front page (72) Inventor Yurie Koyama 7-3-1 Hongo, Bunkyo-ku, Tokyo, inside the University of Tokyo Hospital (72) Inventor Kumiko Taniguchi 1-14-2 Yushima, Bunkyo-ku, Tokyo (72) Inventor Shuichiro Yamaguchi Inventor Shuichiro Yamaguchi 8 Tokojima, Kitajima-cho, Itano-gun, Tokushima Prefecture, Toho Rayon Tokushima Co., Ltd. (58) Field surveyed (Int.Cl. ⁷ , DB name) ) A61L 15/00-15/64

Claims (7)

(57) [Claims] 1. A cellulose sponge produced by subjecting a sponge stock solution containing no viscose and crystalline sodium sulfate to a main raw material and containing no reinforcing fibers to a heat treatment in a temperature range of 35 ° C. to 70 ° C. to coagulate. An absorbent covering and protecting material for a wound, comprising a cellulose sponge, wherein the sponge stock solution is formed into a sheet by coagulating the sponge stock solution to a small thickness. 2. A sponge stock solution containing no viscose and crystalline sodium sulfate as a main raw material and containing no reinforcing fibers is subjected to a heat treatment in a temperature range of 35 ° C. to 70 ° C. until the fluidity is lost by a first temperature holding step. Solidify, then 90 ° C
A cellulose sponge produced by completely coagulating in a second temperature holding step of performing a heat treatment in a temperature range of from about 100 ° C. to 100 ° C., which is formed into a sheet by coagulating the sponge stock solution to a small thickness. An absorbent covering / protecting material for wounds, comprising a cellulose sponge. 3. The absorbent covering / protecting material for wounds comprising a cellulose sponge according to claim 1 or 2, wherein a cutout for inserting a pin or a drain tube of the external fixator is formed. 4. The notch is formed by a linear cut from one end of the cellulose sponge to a substantially central portion and an insertion hole partially notched at the substantially central portion. Item 4. An absorbent covering and protecting material for wounds, comprising the cellulose sponge according to Item 3. 5. The incision is formed by a linear incision from one end of the cellulose sponge to a substantially central portion and a radial incision extending in at least two directions at the substantially central portion. Item 4. An absorbent covering and protecting material for wounds, comprising the cellulose sponge according to Item 3. 6. The notch is formed by an opening notch extending from one end of the cellulose sponge to a substantially central portion and an insertion hole partially notching the substantially central portion. An absorbent covering / protecting material for a wound, comprising the cellulose sponge according to 3. 7. The notch is formed of an opening notch extending from one end of the cellulose sponge to a substantially central portion and a radial notch extending in at least two directions at the substantially central portion. An absorbent covering / protecting material for a wound, comprising the cellulose sponge according to 3.