JP2551755B2 - Method for producing solubilized liquid - Google Patents
Method for producing solubilized liquidInfo
- Publication number
- JP2551755B2 JP2551755B2 JP61094141A JP9414186A JP2551755B2 JP 2551755 B2 JP2551755 B2 JP 2551755B2 JP 61094141 A JP61094141 A JP 61094141A JP 9414186 A JP9414186 A JP 9414186A JP 2551755 B2 JP2551755 B2 JP 2551755B2
- Authority
- JP
- Japan
- Prior art keywords
- fatty acid
- water
- weight
- acid ester
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Colloid Chemistry (AREA)
- General Preparation And Processing Of Foods (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Description
【発明の詳細な説明】 本発明は可溶化液の製造法に関する。詳しくは非水溶
性物質にポリグリセリン脂肪酸エステルと水および多価
アルコールを混合し、可溶化することを特徴とする可溶
化液の製造法に関する。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a method for producing a solubilizing solution. More specifically, the present invention relates to a method for producing a solubilizing solution, which comprises solubilizing a water-insoluble substance by mixing polyglycerin fatty acid ester, water and a polyhydric alcohol.
（産業上の利用分野） 本発明の可溶化液は、飲料、食品、化粧品、医薬品に
添加し、非水溶性物質を均一に可溶化する場合に有用な
ものである。ポリグリセリン脂肪酸エステルは食品添加
物として認可されており、食品工業においては非常に重
要な乳化剤である。(Field of Industrial Application) The solubilizing liquid of the present invention is useful when added to beverages, foods, cosmetics, and pharmaceuticals to uniformly solubilize non-water-soluble substances. Polyglycerin fatty acid ester is approved as a food additive and is a very important emulsifier in the food industry.
（従来の技術） 非水溶性物質は、油類に溶解し水に溶解しないために
非水溶性物質を飲料、食品に添加した場合非水溶性物質
が分離してその利用範囲が限定されている。特に、飲
料、食品類は水を主成分とする製品形態が食しやすいた
め数多く製品化されているが、非水溶性物質を利用する
際はその分離の問題がある。このため非水溶性物質を、
食品用乳化剤を用いて水に乳化、分散させることが検討
されており一部実用化もなされているが、長期保存する
と非水溶性物質の分離の多、非水溶性物質が十分乳化、
分散しないなどの問題がある。(Prior art) Since water-insoluble substances dissolve in oils but not in water, when water-insoluble substances are added to beverages and foods, the water-insoluble substances separate and their use range is limited. . In particular, beverages and foods are produced in many products because the product form containing water as a main component is easy to eat, but there is a problem of separation when a water-insoluble substance is used. Therefore, water-insoluble substances
It has been studied to emulsify and disperse in water using a food-grade emulsifier, and it has been partially put into practical use, but when stored for a long time, many water-insoluble substances are separated, and the water-insoluble substance is sufficiently emulsified.
There are problems such as not distributing.
（発明が解決しようとする問題点） このようなことから、非水溶性物質を可溶化し、製品
に添加し長期にわたって可溶化安定性が良い方法の開発
が望まれていた。(Problems to be Solved by the Invention) Under these circumstances, it has been desired to develop a method of solubilizing a non-water-soluble substance and adding it to a product and having good solubilization stability over a long period of time.
（問題を解決するための手段） 本発明者らは、非水溶性物質を可溶化し、製品に添加
した場合、長期にわたって可溶化安定性の良い可溶化液
を、開発する目的で鋭意研究を行なった結果、非水溶性
物質にポリグリセリン脂肪酸エステルと水および多価ア
ルコールを混合し、可溶化する方法を発明した。(Means for Solving the Problem) The present inventors have earnestly studied for the purpose of developing a solubilized solution having good solubilization stability for a long period of time when a water-insoluble substance is solubilized and added to a product. As a result, the inventors invented a method of solubilizing a water-insoluble substance by mixing a polyglycerin fatty acid ester, water and a polyhydric alcohol.
すなわち、本発明は安全性の高く食品添加物に認可さ
れているポリグリセリン脂肪酸エステルを用い、非水溶
性物質を水および多価アルコールと混合し、可溶化する
方法である。That is, the present invention is a method of solubilizing a water-insoluble substance by mixing it with water and a polyhydric alcohol using a polyglycerol fatty acid ester which is highly safe and is approved as a food additive.
本発明に用いられるポリグリセリン脂肪酸エステル
は、水酸基価が970以下のポリグリセリンの脂肪酸エス
テルである。ポリグリセリン脂肪酸エステルに用いられ
る脂肪酸は、ラウリン酸、ミリスチン酸、パルミチン
酸、ステアリン酸、ベヘニン酸、オレイン酸などの炭素
数12〜22の飽和または不飽和の直鎖脂肪酸であり、これ
らの脂肪酸は、単独またはその混合物でもよい。The polyglycerin fatty acid ester used in the present invention is a polyglycerin fatty acid ester having a hydroxyl value of 970 or less. Fatty acids used for polyglycerin fatty acid esters are saturated or unsaturated straight chain fatty acids having 12 to 22 carbon atoms such as lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, and oleic acid. , Or a mixture thereof.
本発明のポリグリセリン脂肪酸エステルは、水酸基価
が970以下のポリグリセリンのモノ、ジトリの脂肪酸エ
ステルであり、なかでもモノ、ジの脂肪酸エステルが望
ましく、これらは単独またはその混合物で用いることが
できる。The polyglycerin fatty acid ester of the present invention is a monoglyceride fatty acid ester of polyglycerin having a hydroxyl value of 970 or less, and among them, a monoglyceride fatty acid ester and a diglyceride fatty acid ester are preferable, and these can be used alone or in a mixture thereof.
本発明に用いられる非水溶性物質は、オレンジ油、レ
モン油、アンブレット種子油、オリス根油、カナンガ
油、カラシ油、キャラウエイ油、キャロット種子油、グ
レープフルーツ油、ジンジャー油、ホップ油、ミルトル
油、ローズ油、ローズマリー油などの天然香料の他、オ
イゲノール、カプリル酸エチル、ゲラニオール、メント
ール、シトラール、シトロネラール、ボルネオールなど
の合成又は天然の着香料があげられる。又、アナトー色
素、カロチン、オレオレジンなどの油性着色料、ビタミ
ンＡ、ビタミンＥ、ビタミンＤ、ビタミンＫなどの油溶
性ビタミン、オレイン酸、リノール酸、リノレン酸、ア
ラキドン酸、エイコサペンタエン酸、ドコサペンタエン
酸、プロスタグランジンなどの油性物質、オリーブ油、
コーン油、ベニバナ油、魚油などの油脂、ミツロウ、ラ
イスワックス、プロポリスなどのワックスなどがあげら
れる。The water-insoluble substances used in the present invention include orange oil, lemon oil, amblet seed oil, orris root oil, cananga oil, mustard oil, caraway oil, carrot seed oil, grapefruit oil, ginger oil, hop oil, and milltor. In addition to natural flavors such as oil, rose oil and rosemary oil, synthetic or natural flavorings such as eugenol, ethyl caprylate, geraniol, menthol, citral, citronellal and borneol can be mentioned. Also, oily colorants such as annatto pigment, carotene and oleoresin, oil-soluble vitamins such as vitamin A, vitamin E, vitamin D and vitamin K, oleic acid, linoleic acid, linolenic acid, arachidonic acid, eicosapentaenoic acid, docosapenta. Oily substances such as enoic acid and prostaglandins, olive oil,
Examples include oils and fats such as corn oil, safflower oil, and fish oil, and waxes such as beeswax, rice wax, and propolis.
本発明に用いられる多価アルコールは、プロピレング
リコール、グリセリン、ソルビトール、キシリトール、
アラビトール、マルチトール、ラクチトール、ソルビタ
ン、キシロース、アラビノース、マンノース、乳糖、砂
糖、カップリングシュガー、ブドウ糖、酵素水飴、酸糖
化水飴、麦芽糖水飴、麦芽糖、異性化糖、果糖、還元麦
芽糖水飴、還元澱粉糖水飴、蜂蜜などがあげられる。The polyhydric alcohol used in the present invention includes propylene glycol, glycerin, sorbitol, xylitol,
Arabitol, maltitol, lactitol, sorbitan, xylose, arabinose, mannose, lactose, sugar, coupling sugar, glucose, enzyme starch syrup, acid saccharified starch syrup, maltose starch syrup, maltose, isomerized sugar, fructose, reduced maltose starch syrup, reduced starch sugar Examples include starch syrup and honey.
本発明の非水溶性物質は１〜70重量部使用され望まし
くは10〜50重量部使用される。本発明のポリグリセリン
脂肪酸エステルは１〜90重量部使用され、望ましくは10
〜60重量部使用される。The water-insoluble substance of the present invention is used in an amount of 1 to 70 parts by weight, preferably 10 to 50 parts by weight. The polyglycerin fatty acid ester of the present invention is used in an amount of 1 to 90 parts by weight, preferably 10
Used up to 60 parts by weight.
本発明の多価アルコールは１〜90重量部使用され望ま
いくは20〜70重量部使用される。本発明に用いられる水
は、0.1〜50重量部使用され、望ましくは１〜40重量部
使用される。The polyhydric alcohol of the present invention is used in an amount of 1 to 90 parts by weight, preferably 20 to 70 parts by weight. The water used in the present invention is used in an amount of 0.1 to 50 parts by weight, preferably 1 to 40 parts by weight.
本発明に用いられる非水溶性物質、ポリグリセリン脂
肪酸エステル、水、多価アルコールの比率は、可溶化液
の製造および可溶化液の長期安定性を保つのに必要な条
件であり、本発明の比率以外では満足する可溶化液は製
造できず、また可溶化液の長期安定性も悪い。The ratio of the water-insoluble substance, the polyglycerin fatty acid ester, water, and the polyhydric alcohol used in the present invention is a condition necessary for producing the solubilized liquid and maintaining the long-term stability of the solubilized liquid. Except for the ratio, a solubilized solution that is satisfactory cannot be produced, and the long-term stability of the solubilized solution is poor.
本発明のポリグリセリン脂肪酸エステルと共に可溶化
液にグリセリン脂肪酸エステル、ショ糖脂肪酸エステ
ル、プロピレングリコール脂肪酸エステル、レシチン、
ソルビタン脂肪酸エステルを配合しても良い。Glycerin fatty acid ester, sucrose fatty acid ester, propylene glycol fatty acid ester, lecithin, in the solubilized liquid together with the polyglycerin fatty acid ester of the present invention,
You may mix | blend a sorbitan fatty acid ester.
（作用） 本発明のポリグリセリン脂肪酸エステルは非常に親水
性が強く、HLB値が大きい界面活性剤であるために、非
水溶性物質を乳化、可溶化する力が大きいと推定され
る。(Function) Since the polyglycerin fatty acid ester of the present invention is a surfactant having a very strong hydrophilicity and a large HLB value, it is presumed that it has a large ability to emulsify and solubilize a water-insoluble substance.
次に本発明を実施例によって説明する。 Next, the present invention will be described with reference to examples.
実施例１ オレンジオイル20gにデカグリセリンモノステアレー
ト（ポリグリセリンの水酸基価＝890）20g、ソルビット
50g、水10gを加えてホモミキサーで70℃、７分間、撹拌
して均一な溶液を得た。この可溶化液を0.1gをクエン酸
でpH＝3.5に調製した13％グラニュー糖水溶液100mlに添
加したところ、オレンジオイルは簡単に可溶化した。そ
の後、３ケ月放置して油滴や浮遊物の発生の有無とpHの
変化を測定した。その結果、油滴や浮遊物の発生は認め
られず、またpHも変化しなかった。Example 1 20 g of orange oil, 20 g of decaglycerin monostearate (hydroxyl value of polyglycerin = 890), sorbit
50 g and 10 g of water were added, and the mixture was stirred with a homomixer at 70 ° C. for 7 minutes to obtain a uniform solution. When 0.1 g of this solubilized solution was added to 100 ml of a 13% granulated sugar aqueous solution adjusted to pH = 3.5 with citric acid, orange oil was easily solubilized. After that, the mixture was left for 3 months, and the presence or absence of oil droplets and floating substances and the change in pH were measured. As a result, no oil droplets or floating substances were observed, and the pH did not change.
実施例２ 80％トコフェロール液10gにデカグリセリンモノラウ
レート20g、70％マルチトール69g、ソルビタンモノオレ
ート1gを加えてホモミキサーで70℃、７分間、撹拌して
均一な溶液を得た。この可溶化液を0.1gをクエン酸でpH
＝3.5に調製した13％グラニュー糖水溶液100mlに添加し
たところ、トコフェロールは簡単に可溶化した。その
後、３ケ月放置して油滴や浮遊物の発生の有無とpHの変
化を測定した。その結果、油滴や浮遊物の発生は認めら
れず、またpHも変化しなかった。Example 2 To 10 g of 80% tocopherol solution, 20 g of decaglycerin monolaurate, 69 g of 70% maltitol and 1 g of sorbitan monooleate were added, and stirred with a homomixer at 70 ° C. for 7 minutes to obtain a uniform solution. 0.1 g of this solubilized solution was added with citric acid.
When added to 100 ml of 13% granulated sugar aqueous solution prepared to = 3.5, tocopherol was easily solubilized. After that, the mixture was left for 3 months, and the presence or absence of oil droplets and floating substances and the change in pH were measured. As a result, no oil droplets or floating substances were observed, and the pH did not change.
比較例１ 実施例１において、デカグリセリンモノステアリン酸
エステルの代わりにモノステアリン酸グリセリドを使用
した以外は全く同様に行なった。その結果、オレンジオ
イルの少量の油滴とネックリングが観察された。Comparative Example 1 The procedure of Example 1 was repeated except that monostearic acid glyceride was used instead of decaglycerin monostearate. As a result, a small amount of orange oil droplets and a neck ring were observed.
（本発明の効果） 本発明のポリグリセリン脂肪酸エステルを用いた可溶
化液は実施例の結果から明らかな様に、飲料、食品、化
粧品、医薬品に応用すると良好な可溶化液となり、しか
も長期安定性を示す。そのため、今まで応用範囲が限ら
れていた非水溶性物質を利用するに際して、特別の処理
を必要とせずに、簡単に利用することができるためその
応用範囲は拡大する。(Effect of the present invention) As is clear from the results of the examples, the solubilizing solution using the polyglycerin fatty acid ester of the present invention becomes a good solubilizing solution when applied to beverages, foods, cosmetics, and pharmaceuticals, and has long-term stability. Shows sex. Therefore, when a water-insoluble substance which has a limited application range is used, it can be easily used without requiring a special treatment, so that the application range is expanded.
───────────────────────────────────────────────────── フロントページの続き (56)参考文献 特開 昭56−37040（ＪＰ，Ａ) 特開 昭61−37710（ＪＰ，Ａ) 特開 昭60−118164（ＪＰ，Ａ) 特開 昭62−419（ＪＰ，Ａ) 特開 昭62−106837（ＪＰ，Ａ) 特公 平６−36862（ＪＰ，Ｂ２) ─────────────────────────────────────────────────── --Continued from the front page (56) References JP-A-56-37040 (JP, A) JP-A-61-37710 (JP, A) JP-A-60-118164 (JP, A) JP-A-62- 419 (JP, A) JP 62-106837 (JP, A) JP-B 6-36862 (JP, B2)
Claims (2)
料より選ばれる１種又は２種以上よりなる非水溶性物質
１〜70重量部に水酸基価970以下のポリグリセリンをモ
ノ、ジ、トリエステル化して得られるポリグリセリン脂
肪酸エステル１〜90重量部と水0.1〜50重量部および多
価アルコール１〜90重量部を混合し可溶化することを特
徴とする可溶化液の製造法（但し、使用するポリグリセ
リン脂肪酸エステルの構成脂肪酸が全て不飽和脂肪酸の
場合、使用する多価アルコールの割合が可溶化液中にお
いて０〜40重量％の場合を除く）。1. A mono-, di-, or tri-glycerin having a hydroxyl value of 970 or less in 1 to 70 parts by weight of a water-insoluble substance consisting of one or more selected from natural or synthetic essential oils, pigments, vitamins, and flavors. 1 to 90 parts by weight of polyglycerin fatty acid ester obtained by esterification, 0.1 to 50 parts by weight of water, and 1 to 90 parts by weight of polyhydric alcohol are mixed and solubilized to prepare a solubilizing solution (however, Except when the constituent fatty acids of the polyglycerin fatty acid ester used are all unsaturated fatty acids, the proportion of the polyhydric alcohol used is 0-40% by weight in the solubilized liquid).
炭素数12〜22の直鎖脂肪酸である特許請求の範囲第１項
記載の可溶化液の製造法。2. The method for producing a solubilized solution according to claim 1, wherein the fatty acid of the polyglycerin fatty acid ester is a straight chain fatty acid having 12 to 22 carbon atoms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61094141A JP2551755B2 (en) | 1986-04-23 | 1986-04-23 | Method for producing solubilized liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61094141A JP2551755B2 (en) | 1986-04-23 | 1986-04-23 | Method for producing solubilized liquid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62250941A JPS62250941A (en) | 1987-10-31 |
| JP2551755B2 true JP2551755B2 (en) | 1996-11-06 |
Family
ID=14102104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61094141A Expired - Lifetime JP2551755B2 (en) | 1986-04-23 | 1986-04-23 | Method for producing solubilized liquid |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2551755B2 (en) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01221307A (en) * | 1988-02-27 | 1989-09-04 | Pentel Kk | Liquid cosmetic |
| JP2848830B2 (en) * | 1988-09-02 | 1999-01-20 | 旭電化工業株式会社 | Method of solubilizing fatty acid esters that are hardly soluble in water |
| JPH0398549A (en) * | 1989-09-11 | 1991-04-24 | Sumitomo Seika Chem Co Ltd | Aqueous composition for aromatizing and seasoning food |
| JPH10504291A (en) | 1994-07-22 | 1998-04-28 | ジー．ディー．サール アンド カンパニー | Self-emulsifying drug delivery system |
| US5990180A (en) * | 1995-03-29 | 1999-11-23 | Mitsubishi Chemical Corporation | Aqueous composition containing solubilized or dispersed oil-soluble substance |
| JP4142742B2 (en) * | 1996-05-23 | 2008-09-03 | 大正製薬株式会社 | Microemulsion |
| JPH11140482A (en) * | 1997-11-13 | 1999-05-25 | T Hasegawa Co Ltd | Rapidly releasing spice powder preparation |
| ATE357155T1 (en) * | 2001-03-22 | 2007-04-15 | Firmenich & Cie | TRANSPARENT MICROEMULSIONS WITH HIGH OIL CONTENT |
| JP4615814B2 (en) * | 2002-10-11 | 2011-01-19 | 小林製薬株式会社 | Liquid external preparation for cold medicine and method for producing the same |
| EP1623694B1 (en) | 2003-05-09 | 2009-11-18 | The Nisshin Oillio Group, Ltd. | Selfemulsifying oily liquid cosmetic |
| KR100953241B1 (en) | 2003-10-10 | 2010-04-16 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | Novel Liquid Preparation Composition |
| JP4397286B2 (en) | 2003-11-28 | 2010-01-13 | 日清オイリオグループ株式会社 | Oil-in-water emulsified cosmetic and method for producing the same |
| WO2006018992A1 (en) * | 2004-08-06 | 2006-02-23 | National Food Research Institute | Aqueous mixture containing higher aliphatic compound |
| JP2006129841A (en) * | 2004-11-09 | 2006-05-25 | Nof Corp | alpha-LIPOIC ACID-CONTAINING AQUEOUS COMPOSITION |
| JP5043588B2 (en) * | 2007-10-12 | 2012-10-10 | 花王株式会社 | Liquid oral composition |
| WO2009078245A1 (en) * | 2007-12-19 | 2009-06-25 | Foodtech Trading Co., Ltd. | Transparent emulsified composition and cosmetic and food containing the same |
| JP4979143B2 (en) * | 2009-03-11 | 2012-07-18 | 日本製粉株式会社 | High oil emulsified oil / fat composition for pregelatinized noodles, production method thereof, sauce for pregelatinized noodles using the composition, and pregelatinized noodles |
| JP4958937B2 (en) * | 2009-04-16 | 2012-06-20 | 日本製粉株式会社 | High oil emulsified oil and fat composition for thawing cooked noodles in microwave oven, method for producing the same, sauce for thawing cooked noodles using the same, and microwave thawing cooked noodles |
| WO2012167900A2 (en) * | 2011-06-07 | 2012-12-13 | Beiersdorf Ag | Cosmetic and dermatological emulsion preparations with improved perfume release |
| CN113243456A (en) * | 2021-06-04 | 2021-08-13 | 优佰特生命科学研究院(广州)有限公司 | Compound stabilizer and application thereof in animal beverage |
| CN118765163A (en) | 2022-02-28 | 2024-10-11 | 不二制油集团控股株式会社 | Oil-in-water emulsion and method for producing same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5637040A (en) * | 1979-08-31 | 1981-04-10 | Nippon Saafuakutanto Kogyo Kk | Oil-in-polyhydric alcohol type emulsifying composition |
| JPS58185537A (en) * | 1982-04-23 | 1983-10-29 | Pola Chem Ind Inc | Polyglycerol ester type compound and cosmetic blended with it |
| JPS60118164A (en) * | 1983-11-30 | 1985-06-25 | Sakamoto Yakuhin Kogyo Kk | Acidic o/w-type emulsion composition |
| JPS60166676A (en) * | 1984-02-09 | 1985-08-29 | Riken Vitamin Co Ltd | Vitamin e solubilized composition |
| JPS6112632A (en) * | 1984-06-27 | 1986-01-21 | Eisai Co Ltd | Composition containing fat-soluble drug |
| JPS6137710A (en) * | 1984-07-31 | 1986-02-22 | Pola Chem Ind Inc | Emulsified composition |
| JPS61113781A (en) * | 1984-11-08 | 1986-05-31 | Tokuyama Soda Co Ltd | Cathode for generating hydrogen |
| JPH0693996B2 (en) * | 1984-12-03 | 1994-11-24 | 武田薬品工業株式会社 | Emulsified composition |
| JPS62419A (en) * | 1985-06-26 | 1987-01-06 | Shiseido Co Ltd | Water-soluble agent containing fat-soluble vitamin |
| JPH0636862A (en) * | 1992-07-14 | 1994-02-10 | Kurabe Ind Co Ltd | Manufacture of heating device |
-
1986
- 1986-04-23 JP JP61094141A patent/JP2551755B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS62250941A (en) | 1987-10-31 |
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