JP2017193525A - Mollusk control technique using natural compound having aldehyde group - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an agent having excellent control effect on mollusk while having low toxicity on humans and animals.SOLUTION: A mollusk control technique uses, as an active ingredient, a compound that is used as a food additive, classified as a terpene or a phenylpropanoid, and has an aldehyde group.SELECTED DRAWING: None

Description

  The present invention relates to mollusk control techniques.

  Mollusks are pests in the agricultural and horticultural scenes, and slugs and maimai associates eat many plants such as rice, vegetables, fruit trees and flower buds. Slugs and maimai associates prefer plant shoots and young leaves to cause damage, so the effects of food damage during the seedling stage are large, and the traces of food damage in the flower buds and the mucus produced during the movement are factors of quality degradation. Sukuringingai is breeding in a wide range of areas in the northern limit of Ibaraki Prefecture, and has been designated as an exotic pest in the Plant Protection Law because of its large intake, mainly paddy field crops. In addition, African Maimai, which is also designated as an exotic harmful animal, has been confirmed to breed mainly in Okinawa, and it can be a host of Cantonese schistosomiasis that can cause death as well as eating damage. Control is needed.

  As for the control of these molluscs, the control method using metaaldehyde is generally known. Methaldehyde wettable powder (trade name: My Killer Sankei Chemical Co., Ltd.), metaaldehyde granule (trade name: Jumbo Tanikun) Lonza Japan Co., Ltd., product name: Name Clean 3 Sankei Chemical Co., Ltd., product name: Namenite Lonza Japan Co., Ltd.) are sold as agricultural chemicals. In the case of killing slugs with 30% wettable powder, pesticides containing metaldehyde as an active ingredient are sprayed with 300 L of 10-fold diluted solution (3000 ppm) per 10a. In the case of granules, it is adjusted to 3 to 10% and sprayed around the strain so as not to be directly applied to the crop. In the case of Sukurimingaigai, 4 kg of 10% granule per 10a is sprayed. Moreover, about the contact effect with the metaaldehyde which eluted in water, it has been reported that half of shellfish whose metal height concentration is 13 ppm and whose shell height is 30 mm or more will die, and will not die in shellfish which is 25 mm or less (non-) Patent Document 1).

  In addition, the home center has a metaaldehyde-inducing insecticide as a pest control agent in accordance with the standards of the Living Pest Control Council (trade name: slug cadang-inducing insecticide Fumakilla Co., Ltd., trade name: Nametox House Sumitomo Chemical Gardening Co., Ltd.) Is sold.

  On the other hand, precautions that restrict the direct application of metaaldehyde to crops were added in 2010 in the pesticide registration in 2010, and most of them were restricted to the usage methods that are placed around the plant stock and crops. As a result, metaaldehyde granules (trade name: Namemeil Daiichi Agricultural Chemicals Co., Ltd.), metaaldehyde / NAC granules (trade name: Greenbait Sankei Chemical Co., Ltd.), metaaldehyde wettable powder (tradename: Nametox Liquid Fuji Green) Co., Ltd. has a pesticide registration but is no longer selling it.

  As the use in pesticides is restricted, the toxicity of metaaldehyde is classified as Category 3 for the evaluation of acute toxicity and Category 2 for evaluation of inhalation toxicity in the classification of Globally Harmonized System of Classification and Labeling of Chemicals (GHS). There are concerns about the impact. In addition, pets accidentally eat processed granules, causing accidents that cause poisoning. Especially in home centers that sell products for general consumers who are not farmers, metaldehyde There is a need for highly safe products that can replace

  A technique that is classified into a terpene type or a phenylpropanoid type known as a natural fragrance and that shows an attracting effect on a mollusk of a compound having an aldehyde group has been proposed. However, there is no known extermination effect other than those describing benzaldehyde derivatives (Patent Documents 1, 2, and 3). Moreover, the extermination effect with respect to the mollusk of the thymol, eugenol, and linalool which are the phenolic compounds classified into a terpene type or a phenylpropanoid type | system | group is already known (nonpatent literature 2, 3).

  In addition, cinnamaldehyde, which is classified as a phenylpropanoid compound and has an aldehyde group, is approved as a bactericidal insecticide component in the United States Environmental Protection Agency (EPA), and at the same time, a technique that has shown a repellent effect on animals. It has been proposed (Patent Document 4).

Application number PCT / JP2014 / 076287 JP2009-161560 US Patent 3 459 771 US Patent 4940583

Agricultural Research Result Information No. 355 classification code 04-01 Journal of the Egyptian Society of Parasitology, vol. 36, no. 2,2006 Rev. Inst. Med. Top. Sao Paulo (5): 281-286, September-October, 2012

  Safe and effective mollusk control technology.

  The present inventors studied the control effect on mollusks of compounds that are classified as naturally occurring terpene or phenylpropanoid and have an aldehyde group, and found not only a repellent effect but also a high control effect. .

  That is, the present invention relates to a mollusc control agent that is classified as a terpene type or a phenylpropanoid type and contains at least one compound having an aldehyde group as an active ingredient. The present invention also provides an effective control technique for mollusks that uses a compound classified as a terpene or phenylpropanoid group and having an aldehyde group as an active ingredient. Here, “control” is a concept that combines both killing and repelling molluscs.

  More specifically, a mollusc control agent containing, as an active ingredient, at least one compound selected from perylaldehyde, citral, and citronellal, which is classified as a terpene group and has an aldehyde group. Alternatively, the present invention relates to a mollusc control agent that contains at least one compound selected from anisaldehyde, cinnamaldehyde, vanillin, and benzaldehyde as an active ingredient, which is classified into a phenylpropanoid type and has an aldehyde group. In addition, these compounds are used on a daily basis and are globally approved as food additives.

  When these aldehydes are formulated and used, polyoxyethylene sugar fatty acid esters, glycerin mono fatty acid esters, sugar fatty acid esters, polyglycerin fatty acid esters, etc., or anions are used as long as they are nonionic surfactants. For surfactants, it is desirable to use surfactants that are approved as food additives such as phospholipids and fatty acid salts. In using these surfactants, it is common to use a mixture of at least one of a nonionic surfactant and an anionic surfactant.

  Provided is an effective control technique for mollusks that uses a compound that is classified as a terpene type or a phenylpropanoid type that is used daily and has an aldehyde group as an active ingredient.

  The molluscicide of the present invention is classified into a terpene type or a phenylpropanoid type and contains at least one selected from compounds having an aldehyde group. Specific examples of the active ingredient include perylaldehyde, citral, citronellal, anisaldehyde, cinnamaldehyde, vanillin, and benzaldehyde, but are not limited thereto.

  As the terpene type or phenylpropanoid type compound selected as an active ingredient and having an aldehyde group, an extract derived from a living organism containing the compound can be used in addition to the compound itself. The concentration used for killing molluscs using these active ingredients is several tens to several hundreds of ppm when continuously contacted with molluscs such as scallops that live in water. When spraying and exterminating molluscs living on the ground directly, it is several hundred ppm to several thousand ppm, and when used as a repellent, it is about one-tenth of these.

  Although the control agent of the present invention can be used directly, it is classified as a terpene type or a phenylpropanoid type and the physical properties of the compound having an aldehyde group are generally fat-soluble. It can be mixed with an agent or the like and further diluted with water for use. As the solvent used at this time, for example, a water-soluble solvent such as alcohols, polyalkylene glycol, dimethyl sulfoxide or the like, or a highly safe solvent such as vegetable oil, fatty acid ester, organic acid ester, intermediate fatty acid dimethylamide, etc. should be used. Is desirable. Moreover, it is common to use surfactant with a solvent, and it is possible to use various existing surfactants. For example, if it is a nonionic surfactant, polyoxyethylene alkyl ether, polyoxyalkylene alkyl ether, polyoxyethylene alkyl ester, polyoxyethylene arylphenyl ether, polyoxyethylene alkylamine, sugar fatty acid ester, glycerin fatty acid ester, Polyoxyethylene sugar fatty acid ester, polyoxyethylene fatty acid ester, polyoxyethylene hydrogenated castor oil, etc., or anionic surfactants such as alkyl sulfonate, alkyl benzene sulfonate, dialkyl sulfosuccinate, polyoxy Ethylene allyl phenyl ether sulfonate and the like can be used. Especially non-ionic surfactant polyoxyethylene sugar fatty acid ester, glycerin mono fatty acid ester, sugar fatty acid ester, polyglycerin fatty acid ester, anionic surfactant phospholipid, fatty acid salt that can be anionic surfactant Is approved as a food additive and should be used. These surfactants can be used alone or in combination.

  The control agent of the present invention can be mixed with starch, dextrin, sugars such as sugar, vegetable oil, animal oil, cereal powder, animal powder, biscuit powder, etc. to prepare a solid preparation based on food. .

  In addition, an antioxidant can be used in combination in a preparation containing a compound that is susceptible to oxidation.

  Specific examples of the present invention are shown below, but the technical scope of the present invention is not limited to the examples.

(Preparation Example 1)
Perylaldehyde (product of Wako Pure Chemical Industries, Ltd.), 95% Citral (product of Sigma Aldrich Japan Co., Ltd.), Citronellal (product of Wako Pure Chemical Industries, Ltd.), 99% Anisaldehyde (product of Tokyo Chemical Industry Co., Ltd.), 98% Cinnamaldehyde (product of Tokyo Chemical Industry Co., Ltd.), 98% vanillin (product of Tokyo Chemical Industry Co., Ltd.), 98% benzaldehyde (product of Wako Pure Chemical Industries, Ltd.), each of the above 7 aldehydes is an anionic surfactant 80% polyoxyethylene styryl phenyl ether sulfate (product of Toho Chemical Co., Ltd., Solpol T-10SPG, hereinafter referred to as T-10SPG) and ethanol (product of Kishida Chemical Co., Ltd.) were added to prepare an emulsion having the weight ratio shown in Table 1 below. did. As a control, a white sample containing no aldehyde was also prepared as shown in Table 2 below.

(Preparation Example 2)
98% cinnamaldehyde, T-10SPG as an anionic surfactant, or diethanolamine laurate as a fatty acid salt (98% lauric acid, Tokyo Chemical Industry Co., Ltd. product, 99% diethanolamine, Tokyo Chemical Industry Co., Ltd. product, hereinafter lauric acid DEA), or polyoxyethylene sorbitan monolaurate (a product of Kao Corporation, Rheodor Super TW-L120, hereinafter referred to as TW-L120), which is a nonionic surfactant, and ethanol or dimethyl sulfoxide (xida) as a solvent Chemical products (hereinafter referred to as DMS0) were added to prepare emulsions having the weight ratios shown in Table 3 below. As a control, a white sample containing no aldehyde was prepared as shown in Table 4 below.

(Preparation Example 3)
98% cinnamaldehyde, T-10SPG which is an anionic surfactant, or triethanolamine laurate which is a fatty acid salt (product of 98% triethanolamine Tokyo Chemical Industry Co., Ltd., hereinafter referred to as TEA laurate), or TW-L120, a nonionic surfactant, was added to prepare emulsions having the weight ratios shown in Table 5 below. As a control, a white sample containing no aldehyde was also prepared as shown in Table 5 below.

(Biological test example 1)
In order to test the effect on Sukuri apple mussel, Preparation Example 1, Formula No. The drugs 1 to 7 were filled with a chemical solution diluted with water to a concentration of 100 ppm. In addition, Preparation Example 1, Formula No. Fill the white sample from B1 to B3 with a solution diluted in the same manner as the above-mentioned 100 ppm dilution of the drug, release 5 Sukuringingaigai (shell mouth long diameter 15 to 25 mm), leave a gap in the upper part and close the lid. Observation and investigation were conducted in a constant temperature room for 7 days. A chemical solution obtained by diluting metaaldehyde (product of Wako Pure Chemical Industries, Ltd.) with water to a concentration of 100 ppm as a comparative control drug was used. The test results are shown in Table 6 below.

(Biological test example 2)
In order to test the effect on Sukuri apple mussel, Preparation Example 1, Formula No. The chemicals according to 1 and 5 were filled with a chemical diluted with water to a concentration of 10, 30, and 100 ppm. In addition, Preparation Example 1, Formula No. Fill the white sample from B1 to B3 with a solution diluted in the same manner as the above-mentioned 100 ppm dilution of the drug, release 5 Sukuringingaigai (shell mouth long diameter 15 to 25 mm), leave a gap in the upper part and close the lid. Observation and investigation were conducted in a constant temperature room for 7 days. A chemical solution obtained by diluting metaaldehyde (product of Wako Pure Chemical Industries, Ltd.) with water to a concentration of 10, 30, or 100 ppm as a comparative control drug was used. The test results are shown in Table 7 below.

(Biological test example 3)
In order to test the effect on Sukuri apple mussel, Preparation Example 1, Formula No. 1 was placed in a 500 ml plastic container. 5, Preparation Example 2, Formulation No. 8 to 10 drugs were filled with a chemical solution diluted with water to a concentration of 100 ppm. In addition, the formulation No. Fill the white sample from B1 to B9 with a solution diluted as in the case of the above-mentioned 100 ppm dilution of the drug, release 5 Sukuringingaigai (shell mouth long diameter 15 to 25 mm), leave a gap at the top, cover with 20 Observation and investigation were conducted in a constant temperature room for 7 days. A chemical solution obtained by diluting metaaldehyde (product of Wako Pure Chemical Industries, Ltd.) with water to a concentration of 100 ppm as a comparative control drug was used. The test results are shown in Table 8 below.

(Biological test example 4)
Formulation No. 1 according to Preparation Example 1 and Preparation Example 2 was tested for the effect on slugs. The chemical | medical solution which diluted 1-10 chemical | medical agents with water to 2500 ppm was adjusted. Further, the formulation No. 1 according to Preparation Example 1 and Preparation Example 2 was used. The white samples of B1 to B9 were diluted and adjusted in the same manner as in the case of the aforementioned 2500 ppm drug dilution. Place one teacup 4 to 5 cm long in a plastic petri dish (9 cm in diameter x 1 cm in height), and spray each adjusted solution on the entire petri dish with the chakoura slug once using a small glass spray. did. The spray amount was 1.2 ml per petri dish. After spraying, the lid was covered and observation was conducted in a constant temperature room at 20 ° C. for 7 days. Each drug was performed in triplicate. As a control drug, methaaldehyde wettable powder (metaaldehyde 0.3%, trade name: Nametox solution undiluted solution spray) and mixed liquid of natural substituted phenol and copper compound (trade name: sludge extermination shower Sumitomo Chemical Gardening) A spray test was conducted in the same manner. The test results are shown in Table 9 below.

(Biological Test Example 5)
In order to test the effect on slugs, the formulation no. The chemical | medical solution which diluted the chemical | medical agent of 11-13 with water to 250, 500, 1000, 1500, 3000 ppm was adjusted. In addition, the formulation No. 1 according to Preparation Example 1 and Preparation Example 3. The white samples of B1 and B10 to B12 were diluted and adjusted in the same manner as in the above-described dilution of 3000 ppm of the drug. Place one teacup 4 to 5 cm long in a plastic petri dish (9 cm in diameter x 1 cm in height), and spray each adjusted solution on the entire petri dish with the chakoura slug once using a small glass spray. did. The spray amount was 1.2 ml per petri dish. After spraying, the lid was covered and observation was conducted in a constant temperature room at 20 ° C. for 7 days. Each drug was performed in triplicate. As a control agent, a spray test was conducted in the same manner using a metaaldehyde wettable powder and a mixed liquid of a natural substituted phenol and a copper compound in the same manner as in Biological Test Example 4. The test results are shown in Table 10 below.

  As a result, the control effect on molluscs of terpene-based or phenylpropanoid-based compounds having an aldehyde group was revealed.

Claims (6)

  A mollusc control agent containing at least one compound classified as a terpene or phenylpropanoid compound and having an aldehyde group as an active ingredient.   A mollusc control agent containing, as an active ingredient, at least one compound selected from the group consisting of perylaldehyde, citral and citronellal, which is classified as a terpene group and has an aldehyde group.   A molluscicidal control agent comprising at least one compound selected from anisaldehyde, cinnamaldehyde, vanillin and benzaldehyde as an active ingredient, which is classified into a phenylpropanoid system and has an aldehyde group.   The at least 1 sort (s) selected from polyoxyethylene sugar fatty acid ester, glycerol mono-fatty acid ester, sugar fatty acid ester, and polyglycerol fatty acid ester is used as a nonionic surfactant. A mollusc control agent as described in 1.   The mollusc control agent according to claim 1, 2 or 3, wherein at least one selected from phospholipids and fatty acid salts is used as an anionic surfactant.   A method for controlling mollusks using a compound classified as a terpene or phenylpropanoid and having an aldehyde group as an active ingredient.