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JP2015513557A5 - - Google Patents

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Publication number
JP2015513557A5
JP2015513557A5 JP2014561064A JP2014561064A JP2015513557A5 JP 2015513557 A5 JP2015513557 A5 JP 2015513557A5 JP 2014561064 A JP2014561064 A JP 2014561064A JP 2014561064 A JP2014561064 A JP 2014561064A JP 2015513557 A5 JP2015513557 A5 JP 2015513557A5
Authority
JP
Japan
Prior art keywords
agent according
therapeutic agent
pain
peripheral neuropathy
neuropathic pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014561064A
Other languages
Japanese (ja)
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JP2015513557A (en
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/029258 external-priority patent/WO2013134336A2/en
Publication of JP2015513557A publication Critical patent/JP2015513557A/en
Publication of JP2015513557A5 publication Critical patent/JP2015513557A5/ja
Pending legal-status Critical Current

Links

Claims (4)

ダプター関連キナーゼ1(AAK1)阻を含む、疼痛を治療又は管理するための治療剤 Adapter including associated kinase 1 (AAK1) INHIBITOR, therapeutic agents for treating or managing pain. 前記疼痛が神経因性疼痛である、請求項1に記載の治療剤The therapeutic agent according to claim 1, wherein the pain is neuropathic pain. 前記神経因性疼痛が線維筋痛又は末梢神経障害である、請求項2に記載の治療剤The therapeutic agent according to claim 2, wherein the neuropathic pain is fibromyalgia or peripheral neuropathy. 前記末梢神経障害が糖尿病性神経障害である、請求項3に記載の治療剤The therapeutic agent according to claim 3, wherein the peripheral neuropathy is diabetic neuropathy.
JP2014561064A 2012-03-09 2013-03-06 Inhibition of adapter-related kinase 1 for the treatment of pain Pending JP2015513557A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261608849P 2012-03-09 2012-03-09
US61/608,849 2012-03-09
PCT/US2013/029258 WO2013134336A2 (en) 2012-03-09 2013-03-06 Inhibition of adaptor associated kinase 1 for the treatment of pain

Publications (2)

Publication Number Publication Date
JP2015513557A JP2015513557A (en) 2015-05-14
JP2015513557A5 true JP2015513557A5 (en) 2016-04-21

Family

ID=47884616

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014561064A Pending JP2015513557A (en) 2012-03-09 2013-03-06 Inhibition of adapter-related kinase 1 for the treatment of pain

Country Status (14)

Country Link
US (4) US20140080834A1 (en)
EP (2) EP3235499A3 (en)
JP (1) JP2015513557A (en)
CN (1) CN104220071A (en)
AU (1) AU2013230066A1 (en)
CA (1) CA2866145A1 (en)
DK (1) DK2822555T3 (en)
ES (1) ES2657061T3 (en)
HK (1) HK1199814A1 (en)
HU (1) HUE036040T2 (en)
NO (1) NO2935475T3 (en)
PL (1) PL2822555T3 (en)
PT (1) PT2822555T (en)
WO (1) WO2013134336A2 (en)

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US8901305B2 (en) 2012-07-31 2014-12-02 Bristol-Myers Squibb Company Aryl lactam kinase inhibitors
WO2014130258A1 (en) 2013-02-22 2014-08-28 Bristol-Myers Squibb Company 5h-chromeno[3,4-c]pyridines as inhibitors of adaptor associated kinase 1 (aak1)
WO2014175370A1 (en) * 2013-04-25 2014-10-30 塩野義製薬株式会社 Pyrrolidine derivative and pharmaceutical composition containing same
ES2633987T3 (en) * 2013-07-02 2017-09-26 Bristol-Myers Squibb Company Tricyclic pyrido-carboxamide derivatives as ROCK inhibitors
US10253027B2 (en) 2013-07-08 2019-04-09 Bristol-Myers Squibb Company Aryl lactam kinase inhibitors
AR097543A1 (en) * 2013-09-06 2016-03-23 Lexicon Pharmaceuticals Inc COMPOUNDS BASED ON IMIDAZO [1,2-b] PIRIDAZINE, COMPOSITIONS THAT INCLUDE THEM AND THEIR METHODS OF USE
TW201542550A (en) 2013-09-06 2015-11-16 Lexicon Pharmaceuticals Inc Pyrazolo[1,5-a]pyrimidinyl compound, composition comprising the same, and method of using the same
EA029744B1 (en) * 2013-09-11 2018-05-31 Бристол-Майерс Сквибб Компани Aryl ether-base kinase inhibitors
CN105979950A (en) * 2013-10-11 2016-09-28 百时美施贵宝公司 Pyrrolotriazine kinase inhibitors
US9932320B2 (en) * 2014-01-31 2018-04-03 Bristol-Myers Squibb Company Quinoline-based kinase inhibitors
TW201620911A (en) * 2014-03-17 2016-06-16 雷西肯製藥股份有限公司 Inhibitors of adapter associated kinase 1, compositions comprising them, and methods of their use
SG11201608195QA (en) 2014-04-02 2016-10-28 Bristol Myers Squibb Co Biaryl kinase inhibitors
CN107108552A (en) * 2014-08-05 2017-08-29 百时美施贵宝公司 Heterocyclic kinase inhibitors
AU2015342887B2 (en) 2014-11-06 2020-09-10 Bial - R&D Investments, S.A. Substituted pyrazolo(1,5-a)pyrimidines and their use in the treatment of medical disorders
US10174044B2 (en) 2015-04-10 2019-01-08 Bristol-Myers Squibb Company Fused pyridines as kinase inhibitors
CN108290843B (en) 2015-10-01 2021-08-24 百时美施贵宝公司 Biaryl kinase inhibitors
ES2765730T3 (en) 2015-10-01 2020-06-10 Bristol Myers Squibb Co Biaryl kinase inhibitors
WO2017176961A1 (en) 2016-04-06 2017-10-12 Lysosomal Therapeutics Inc. Imidazo [1,5-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders
JP7038063B2 (en) 2016-04-06 2022-03-17 リソソーマル・セラピューティクス・インコーポレイテッド Pyrazolo [1,5-a] pyrimidinylcarboxamide compounds and their use in the treatment of medical disorders
EP3452481A4 (en) * 2016-05-05 2020-02-26 Lysosomal Therapeutics Inc. SUBSTITUTED IMIDAZO[1,2-b
US11352328B2 (en) 2016-07-12 2022-06-07 Arisan Therapeutics Inc. Heterocyclic compounds for the treatment of arenavirus
KR102590438B1 (en) * 2020-10-16 2023-10-18 김홍렬 Composition for preventing or disinfecting coronavirus infection or infectious disease comprising a PMCA inhibitor
KR102590444B1 (en) * 2020-10-16 2023-10-18 김홍렬 Composition for treating coronavirus infection or disease casued by coronavirus infection comprising PMCA inhibitor
WO2023196584A2 (en) * 2022-04-08 2023-10-12 New York University Endocytosis inhibitors and their use for pain treatment

Family Cites Families (6)

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US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
AU2515992A (en) 1991-08-20 1993-03-16 Genpharm International, Inc. Gene targeting in animal cells using isogenic dna constructs
US20070049591A1 (en) * 2005-08-25 2007-03-01 Kalypsys, Inc. Inhibitors of MAPK/Erk Kinase
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KR101324804B1 (en) * 2008-05-13 2013-11-01 아이알엠 엘엘씨 Fused nitrogen containing heterocycles and compositions thereof as kinase inhibitors
US8461336B2 (en) * 2008-09-04 2013-06-11 Anacor Pharmaceuticals, Inc. Boron-containing small molecules

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