JP2014184963A - Connected container - Google Patents

Abstract

PROBLEM TO BE SOLVED: To easily switch a linear array state and a curved array state of a connected container formed of optically transparent and hard material.SOLUTION: A connected container 1 includes a plurality of container main bodies 2 each having a cylindrical side wall part 4 and a bottom surface part 5 which closes one end of the side wall part 4 and is optically transparent; and a connecting part 3 which connects the respective container main bodies 2 in an arrayed state approximately parallel to their longitudinal axes. The connecting part 3 has a cross section, of which a section modulus in a direction parallel to the longitudinal axis of the container main body 2 is larger than a section modulus in a direction orthogonal to the longitudinal axis, on at least a part between the adjacent respective container main bodies 2.

Description

  The present invention relates to a connection container.

  Conventionally, in order to perform high-sensitivity optical detection and measurement, a connection container integrally formed into a form in which a plurality of containers are linearly connected by a connecting portion using a material having high transmittance for visible light is known. ing. According to this connection container, nucleic acid amplification reaction and highly sensitive optical measurement can be easily performed using the same container.

JP 2012-196177 A

  However, in the connection container of Patent Document 1, a material having high permeability is limited to glass or a resin material having permeability comparable to glass. These are generally rigid and hard materials. Therefore, it is difficult to curve the connection container around an axis parallel to the longitudinal axis of each container.

  The present invention has been made in view of the above-described circumstances, and easily combines a state in which a plurality of containers are connected and arranged linearly and a state in which the container is curved around an axis parallel to the longitudinal axis of the container. It aims at providing the connection container which can be switched.

In order to achieve the above object, the present invention provides the following means.
In one embodiment of the present invention, a plurality of container main bodies each including a cylindrical side wall part and an optically transparent bottom surface part closing one end of the side wall part, and the container main bodies are substantially parallel to their longitudinal axes. A connecting portion connected in a state of being arranged in the at least one portion between the adjacent container bodies, the section coefficient in a direction parallel to the longitudinal axis of the container body being the longitudinal axis. Provided is a connecting container having a cross section larger than a section modulus in an orthogonal direction.

  According to this aspect, the connecting portion is more likely to bend with respect to a moment acting in a direction perpendicular to the longitudinal axis than to a moment acting in a direction parallel to the longitudinal axis of the container body because of the section modulus. It is possible to easily switch between a state in which a plurality of container bodies are arranged in a straight line and a state in which they are arranged in a curved line by bending the connecting portion while keeping the longitudinal axis of the container body in parallel.

In the said aspect, each said container main body may be equipped with the fitting part which fits the outer periphery of the said side wall part so that attachment or detachment is possible, and the said connection part may connect each said adjacent fitting part.
By doing in this way, by making the outer periphery of each side wall part fit into a fitting part, it will be in the state where several container main bodies were connected by making the longitudinal axis into parallel by the connection part. Since the connecting portion is not directly connected to the side wall portion, stress concentration generated at the base of the connecting portion when a moment is applied can be prevented from acting on the side wall portion, and the soundness of the container body can be maintained. .

In the said aspect, each said container main body is provided with the cover body attached to the opening of the other end of the said side wall part so that opening and closing is possible, and the said connection part may connect each said adjacent cover body. .
By doing in this way, a sample can be accommodated in a side wall part in the state which removed and opened the cover body from the opening of the other end of a side wall part. Further, by attaching lids to the respective side wall portions so as to close all the openings of the side wall portions with the lid bodies, the plurality of container main bodies are connected by the connecting portions with the longitudinal axes parallel to each other.

In this state, it is possible to easily switch between a state in which a plurality of container main bodies are arranged in a straight line and a state in which they are arranged in a curve by curving the connecting portion. Moreover, a side wall part can be replaced | exchanged by comprising so that a cover body may be attached or detached to a side wall part.
In the above aspect, each container body has a lid attached to the opening at the other end of the side wall portion so that the opening can be opened and closed, and a fitting portion for detachably fitting the outer periphery of the side surface of the lid. The connecting part may connect the adjacent fitting parts adjacent to each other.

  By doing in this way, a lid is attached to each side wall so that the opening at the other end of the side wall is closed with a lid, and the outer periphery of the lid is fitted to the fitting portion, so that a plurality of The container main body is connected by the connecting portion with the longitudinal axis parallel. In this state, it is possible to easily switch between a state in which a plurality of container main bodies are arranged in a straight line and a state in which they are arranged in a curve by curving the connecting portion.

Since the connecting portion is not directly connected to the side wall portion, stress concentration generated at the base of the connecting portion when a moment is applied can be prevented from acting on the side wall portion, and the soundness of the container body can be maintained. .
In the said aspect, each said container main body is provided with the cover body attached to the opening of the other end of the said side wall part so that opening and closing is possible, and the said connection part connects the said cover bodies which adjoin each other. And a container connecting portion that connects the adjacent side wall portions.

  By doing in this way, when all the openings of the side wall portions are closed with the lid, the plurality of container main bodies are provided with the lid connecting portion and the container connecting portion so that their longitudinal axes are substantially parallel to each other. Are double-connected. Thereby, the connection part which has a cross section larger than the section modulus of the direction orthogonal to the said longitudinal axis in the direction parallel to a longitudinal axis can be comprised easily.

  According to the present invention, it is possible to easily switch between a state in which a plurality of containers are connected and arranged in a straight line and a state in which the plurality of containers are curved around an axis parallel to the longitudinal axis of the container.

It is a perspective view which shows the connection container which concerns on the 1st Embodiment of this invention. It is the perspective view which fractured | ruptured a part which shows the cross section of the connection part of the connection container of FIG. It is a perspective view which shows the connection container which concerns on the 2nd Embodiment of this invention. It is a disassembled perspective view which shows the connection container of FIG. It is a perspective view which shows the connection container which concerns on the 3rd Embodiment of this invention. It is a disassembled perspective view which shows the connection container of FIG. It is a perspective view which shows the connection container which concerns on the 4th Embodiment of this invention. It is a disassembled perspective view which shows the connection container of FIG. It is a perspective view which shows the connection container which concerns on the 5th Embodiment of this invention. It is the perspective view which shows the 1st modification of the connection container of FIG. 1, (a) Perspective view, (b) The perspective view which shows one cross section of a connection part, (c) The other cross section of a connection part. FIG. 7A is a perspective view showing a second modification of the connection container of FIG. 1, FIG. 8B is a perspective view showing one transverse section of the connection portion, and FIG. 9C is a perspective view showing another cross section of the connection portion. It is a perspective view which shows the usage example of the connection container of FIG.

The connection container 1 which concerns on the 1st Embodiment of this invention is demonstrated below with reference to drawings.
The connection container 1 which concerns on this embodiment is provided with the some container main body 2 which has the opening which can insert / remove a sample, and the connection part 3 which connects between each container main body 2 as FIG. 1 shows. .
As shown in FIG. 1, the container body 2 includes a cylindrical side wall portion 4 and an optically transparent flat bottom surface portion 5 that closes one end of the side wall portion 4, and an opening 4 a at the other end. (See FIG. 2).

Further, the container body 2 is integrally formed of a hard material (for example, cycloolefin resin, acrylic resin, polycarbonate, etc.) having a sufficiently high transmittance with respect to visible light, preferably a transmittance of 70% or more. Molded.
The bottom surface portion 5 is formed substantially perpendicular to the longitudinal axis of the side wall portion 4.
As shown in FIG. 1, the connecting portion 3 is a beam-like portion arranged so as to span the adjacent side wall portions 4 of the plurality of container main bodies 2 arranged with the longitudinal axes in parallel.

  The connecting portion 3 is made of a material having an appropriate elasticity with a bending stress of 90 MPa or less (preferably, polypropyne, polyethylene, vinyl chloride, ABS resin, silicone, etc.). The connection part 3 may be comprised with the same material as the container main body 2, and the container main body 2 should just be integrally molded in that case. Moreover, what is necessary is just to carry out 2 color molding with the container main body 2, when it is comprised with the material different from the container main body 2. FIG.

  In the present embodiment, the double-supported beam-like connecting portion 3 has a certain cross-sectional shape along its length direction. That is, as shown in FIG. 2, the cross section 6 of the connecting portion 3 has a long side with a dimension A in a direction parallel to the longitudinal axis of the container body 2 and a short side with a dimension B in a direction perpendicular to the long side. The section modulus in the direction parallel to the longitudinal axis of the container body 2 is formed larger than the section modulus in the direction orthogonal to the longitudinal axis.

Next, the operation of the connection container 1 according to this embodiment configured as described above will be described.
In order to perform a nucleic acid amplification reaction using a PCR apparatus for a sample such as ultrapure water using the connection container 1 according to the present embodiment, a plurality of connection containers 1 are accommodated in an accommodation unit provided in the PCR apparatus. . The accommodation unit of the PCR device usually includes a plurality of recesses arranged in a matrix, and the pitch of these recesses matches the pitch of the container body of the connection container 1. Therefore, as a form in which a plurality of container main bodies 2 are arranged in a straight line, the connection containers 1 can be accommodated in the recesses for each row only by matching the container main bodies 2 with the respective recesses of the accommodating portion.

In this case, according to the connection container 1 which concerns on this embodiment, the connection part 3 has high rigidity with respect to the moment of the direction in alignment with the longitudinal axis of the container main body 2, and the weight of the container main body 2 is also the same. Because it is small, it is hard to bend. Therefore, the connection container 1 maintains the linear form irrespective of gravity, and can be easily accommodated in the accommodation portion.
Each container main body 2 accommodated in the recess is supplied with a sample and a fluorescent dye that can emit light by binding to the amplified nucleic acid, and a nucleic acid amplification reaction is performed.

  Next, the sample after the nucleic acid amplification reaction is irradiated with excitation light to perform optical measurement. In this case, it is necessary to sequentially irradiate the sample contained in each container body 2 with excitation light, and it is preferable to perform measurement continuously. For continuous measurement, as shown in FIG. 12, the container body 2 is arranged along a hole 31 arranged in a circumferential direction on a disk-shaped measurement stage 30, and the measurement stage 30 is rotated. The method of irradiating excitation light from the bottom face part 5 side of the container main body 2 can be mentioned.

  In this case, according to the connection container 1 which concerns on this embodiment, the connection part 3 has low rigidity with respect to the moment of the direction orthogonal to the longitudinal axis of the container main body 2. FIG. Therefore, the connecting portion 3 can be bent relatively easily in this direction. And the container main body 2 can be arranged in the curve shape along the circumferential direction on the measurement stage 30 by making the connection part 3 bend.

  Thus, according to the connection container 1 which concerns on this embodiment, it is easy to make the several container main body 2 into the state arranged in the linear form and the state arranged in the curve form only by curving the connection part 3. FIG. There is an advantage that it can be switched. In this case, since the longitudinal axis of the container body 2 is maintained in a substantially parallel state, the position of the bottom surface portion 5 can be maintained at a constant height position, and optical measurement for irradiating excitation light can be easily performed. There is an advantage that can be done.

Next, the connection container 7 which concerns on the 2nd Embodiment of this invention is demonstrated below with reference to drawings.
In description of this embodiment, the same code | symbol is attached | subjected to the location which shares a structure with the connection container 1 which concerns on 1st Embodiment mentioned above, and description is abbreviate | omitted.
As shown in FIGS. 3 and 4, the connection container 7 according to the present embodiment includes the container body 2 including the side wall part 4 and the fitting part 8 for fitting the side wall part 4, and the connection part 9 is In the point which has connected between the adjacent fitting parts 8, it differs from the connection container 1 which concerns on 1st Embodiment.

In the connection container 7 according to the present embodiment, the fitting portion 8 is formed in an annular shape as shown in FIG. 3, and the inner diameter dimension of the inner hole 8 a is substantially equal to or slightly smaller than the outer diameter dimension of the side wall portion 4. Is formed.
Moreover, the connection part 9 is a beam-shaped part which connects the two fitting parts 8 so that it may span over the adjacent position of the some fitting parts 8 arranged in a straight line. The cross-sectional shape of the connecting portion 9 is the same as that in the first embodiment.

The operation of the connection container 7 according to this embodiment configured as described above will be described below.
According to the connection container 7 which concerns on this embodiment, while the container main body 2 is comprised by fitting the outer periphery of the side wall part 4 to the inner hole 8a of the fitting part 8, these container main bodies 2 are the longitudinal axis. Are connected by the connecting portion 9 in parallel. Therefore, it is possible to easily switch between a configuration in which the connecting portions 9 are straight and arranged in a straight line and a configuration in which the connecting portions 9 are curved and arranged in a curved shape.

  In this case, since the connecting portions 9 are connected to the respective fitting portions 8 and are not directly connected to the side wall portions 4, stress concentration generated at the base of the connecting portion 9 is applied to the side wall portions when a moment is applied. There is an advantage that the side wall portion 4 can be maintained in a healthy state by preventing acting on the side wall 4. Moreover, there also exists an advantage that the side wall part 4 can be replaced | exchanged by removing the fitting to the fitting part 8 of the side wall part 4. FIG.

Next, the connection container 10 which concerns on the 3rd Embodiment of this invention is demonstrated below with reference to drawings.
In description of this embodiment, the same code | symbol is attached | subjected to the location which shares a structure with the connection container 1 which concerns on 1st Embodiment mentioned above, and description is abbreviate | omitted.
As shown in FIGS. 5 and 6, the connection container 10 according to the present embodiment includes a lid body 11 in which the container body 2 can open and close the opening 4 a at the other end, and the connection portion 14 is adjacent to the lid body 11. The connection container 1 is different from the connection container 1 according to the first embodiment.

  In the connection container 10 according to the present embodiment, the lid body 11 has a shape that fits into the opening 4a of the container body 2, as shown in FIG. It can be closed in a dense state.

  Moreover, the connection part 14 is a beam-shaped part arrange | positioned so that it may span over the adjacent outer peripheral surface of the several cover body 11 arranged with the longitudinal axis parallel. The cross-sectional shape of the connecting portion 14 is the same as that in the first embodiment.

The operation of the connection container 10 according to this embodiment configured as described above will be described below.
According to the connection container 10 which concerns on this embodiment, while the container main body 2 is comprised by making the cover body 11 fit to opening 4a of the other end of the side wall part 4, these container main bodies 2 have the longitudinal axis. They are connected in parallel by the connecting part 14. Therefore, it is possible to easily switch between a configuration in which the connecting portions 14 are straight and arranged in a straight line and a configuration in which the connecting portions 14 are curved and arranged in a curved shape. Moreover, the side wall part 4 can be replaced | exchanged by comprising so that the cover body 11 may be attached or detached to the opening 4a of the side wall part 4. FIG.

Next, the connection container 15 which concerns on the 4th Embodiment of this invention is demonstrated below with reference to drawings.
In description of this embodiment, the same code | symbol is attached | subjected to the location which shares a structure with the connection container 1 which concerns on 1st Embodiment mentioned above, and description is abbreviate | omitted.

  As shown in FIGS. 7 and 8, the connection container 15 according to the present embodiment includes a side wall 4 and a lid 11 detachably fitted to the opening 4 a of the side wall 4. The connecting container 1 according to the first embodiment is provided with a fitting portion 16 for fitting the outer peripheral portion 13 of the lid body 11, and the connecting portion 17 connects the adjacent fitting portions 16. Is different.

In the connection container 15 according to the present embodiment, the fitting portion 16 is formed in an annular shape as shown in FIG. 8, and the inner diameter dimension of the inner hole 16 a is substantially equal to or slightly equal to the outer diameter dimension of the upper side surface portion 4. It is formed small.
Moreover, the connection part 17 is a beam-shaped part which connects the two fitting parts 16 so that it may span over the adjacent position of the some fitting parts 16 arranged in a straight line. The cross-sectional shape of the connecting portion 17 is the same as that in the first embodiment.

The operation of the connection container 15 according to this embodiment configured as described above will be described below.
According to the connection container 15 according to the present embodiment, the outer periphery of the lid body 11 is fitted into the inner hole 16 a of the fitting portion 16, and the lid body 11 is fitted into the opening 4 a of the side wall portion 4, thereby making the container body 2. Is configured. These container main bodies 2 are connected by a connecting portion 17 with their longitudinal axes parallel. Therefore, it is possible to easily switch between a configuration in which the connecting portions 17 are straight and arranged in a straight line and a configuration in which the connecting portions 17 are curved and arranged in a curved shape.

  In this case, the connecting portions 17 are connected to the respective fitting portions 16, and the plurality of container main bodies 2 are not directly connected to the side wall portions 4, so that they are generated at the base of the connecting portions 4 when a moment is applied. Thus, there is an advantage that the stress concentration can be prevented from acting on the side wall portion 4 and the side wall portion 4 can be maintained in a healthy state. Moreover, there also exists an advantage that the side wall part 4 can be replaced | exchanged by removing the fitting to the fitting part 16 of the side wall part 4. FIG.

Next, a connection container 18 according to a fifth embodiment of the present invention will be described below with reference to the drawings.
In description of this embodiment, the same code | symbol is attached | subjected to the location which shares a structure with the connection container 1 which concerns on 1st Embodiment mentioned above, and description is abbreviate | omitted.

  As shown in FIG. 9, the connection container 18 according to the present embodiment includes a side wall 4 and a lid 11 detachably fitted to the opening 4 a of the side wall 4, It differs from the connection container 1 which concerns on 1st Embodiment in the part 19 connecting between the adjacent side wall parts 4, and the cover body connection part 20 connecting between the adjacent cover bodies 11. FIG. .

  In the connection container 18 according to the present embodiment, the container connection part 19 is arranged so as to span the adjacent side wall parts 4 of the plurality of container main bodies 2 arranged with the longitudinal axes parallel to each other, as shown in FIG. This is a beam-shaped part. Further, the lid connecting portion 20 is a beam-like portion arranged so as to span the adjacent outer peripheral portions 13 of the plurality of lids 11 arranged with the longitudinal axes in parallel.

  In the present embodiment, in a state where the lid 11 is fitted to the opening 4a of the side wall portion 4 and the opening 4a is closed, the cross-sectional shape of the connecting portion 21 including the container connecting portion 19 and the lid connecting portion 20 is In the cross section obtained by combining the cross sections of the connecting portions 19 and 20, the cross section coefficient in the direction parallel to the longitudinal axis of the container body 2 is configured to be larger than the cross section coefficient in the direction orthogonal to the longitudinal axis.

The operation of the connection container 18 according to this embodiment configured as described above will be described below.
According to the connection container 18 which concerns on this embodiment, while attaching the cover body 11 to the opening 4a of all the side wall parts 4, the container main body 2 is comprised, and these container main bodies 2 have the longitudinal axis parallel. Thus, the container connecting portion 19 and the lid connecting portion 20 are double connected.

  And in the cross section of the whole connection part which consists of two connection parts 19 and 20, the section modulus of the direction parallel to the longitudinal axis of the container main body 2 is comprised larger than the section coefficient of the direction orthogonal to a longitudinal axis. Therefore, it is possible to easily switch between a form in which a plurality of container bodies 2 are arranged in a straight line and a form in which a plurality of container bodies 2 are arranged in a curved line.

  In each of the above embodiments, the connecting portions 3, 9, 14, 17, and 20 have been described as having a uniform cross section, but instead, this is shown in FIGS. As shown in the drawing, the connecting portion 21 may have one or more cuts 22a and 22b, and the conditions of the section modulus may be satisfied at the positions of the cuts 22a and 22b.

  In other words, in the example shown in FIG. 10A, two V-shaped cuts 22a are provided at intervals on one side surface in the longitudinal direction of the connecting portion 21 having the cross section shown in FIG. 10B. It is provided one by one. The cross section of the connecting portion 21 is at the position of the notch 22a, and as shown in FIG. 10C, the section modulus in the direction parallel to the longitudinal axis of the container body 2 is larger than the section modulus in the direction perpendicular to the longitudinal axis. It is configured. Thereby, the connection part 21 can be easily curved in the position of the notch 22a, and the container main body 2 can be arranged in the shape of a curve.

  Moreover, in the example shown to Fig.11 (a), the slit-shaped notch 22b is provided in the one side surface of the middle part of the longitudinal direction of the connection part 21 which has a cross section shown by FIG.11 (b) at intervals. Yes. The cross section of the connecting portion 21 is at the position of the notch 22b, and as shown in FIG. 11C, the section modulus in the direction parallel to the longitudinal axis of the container body 2 is larger than the section modulus in the direction perpendicular to the longitudinal axis. It is configured. Thereby, the connection part 21 can be easily curved only in the direction of opening the cut 22b at the position of the cut 22b, and the container body 2 can be arranged in a curved shape.

  As specific dimensions, in the case of the connecting containers 1, 7, 10, 15, and 18 in which common 0.2 ml microtubes as the container body 2 are connected at a pitch of 9 mm, the longitudinal direction of the cross section of the connecting portion 21 The dimension of A is 1.5 mm or more, and it is preferable that the dimension of A is twice or more the dimension in the direction B perpendicular to the dimension. Furthermore, the dimension in the direction B is preferably 2 mm or less.

The method for configuring the cross section of the connecting portion 21 so as to satisfy the above-described conditions is not limited to providing the cuts 22a and 22b, and the connecting portion 21 may be provided with a recess or a cavity, or the connecting portion. The material of 21 may be partially different.
Moreover, in embodiment mentioned above, the arrangement | sequence at the time of connecting each container main body 2 by the connection part 3, 9, 14, 17, 19, 20, 21 is not limited to linear form. It may be arranged in a curved line without applying a moment, and may be arranged in a straight line by applying a moment.

DESCRIPTION OF SYMBOLS 1, 7, 10, 15, 18 Connection container 2 Container main body 3, 9, 14, 17, 21 Connection part 4 Side wall part 5 Bottom face part 8, 16 Fitting part 11 Lid body 19 Container connection part 20 Lid body connection part

Claims (5)

A plurality of container main bodies each including a cylindrical side wall and an optically transparent bottom that closes one end of the side wall;
A connecting portion for connecting each container body in a state of being arranged substantially parallel to the longitudinal axis thereof,
The connecting container has a cross-section in which at least a portion between adjacent container bodies has a cross section whose section modulus in a direction parallel to the longitudinal axis of the container body is larger than a section coefficient in a direction perpendicular to the longitudinal axis . Each said container main body is equipped with the fitting part which fits the outer periphery of the said side wall part so that attachment or detachment is possible,
The connection container according to claim 1, wherein the connection part connects the adjacent fitting parts. Each container body includes a lid attached to the opening at the other end of the side wall so that the opening can be opened and closed.
The connection container according to claim 1, wherein the connection portion connects the adjacent lid bodies. Each of the container main bodies includes a lid body that is attached to the opening at the other end of the side wall portion so that the opening can be opened and closed, and a fitting portion that detachably fits the outer periphery of the side surface of the lid body,
The connection container according to claim 1, wherein the connection part connects the adjacent fitting parts. Each container body includes a lid attached to the opening at the other end of the side wall so that the opening can be opened and closed.
The said connection part is equipped with the cover body connection part which connects each said adjacent cover body, and the container connection part which connects each said adjacent said side wall part. Linked container.

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